Guest guest Posted October 28, 2008 Report Share Posted October 28, 2008 Lactose based fillers. If you are lactose intolerant. D Bergy Quoting Maarit <mervi111@...>: > I cannot find the info about what fillings are not good for LDN > capsules???? Can anyone help, please? I got the rx from my doctor > today!!!!!!!!!!!!! > > Maarit > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 28, 2008 Report Share Posted October 28, 2008 Calcium carbonate is not so good, they say it is not absorbed as quickly..... Celia Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 28, 2008 Report Share Posted October 28, 2008 In particular avoid slow release fillers like calcium carbonate. Apart from that it's just a matter of personal choice or where you get it from. For example Skip only uses Avicel so if you use Skip's you have no choice in the matter (which to 99.5% of people is not an issue). Message #71781 posted by Art only days ago says: LDN FILLERS If your Low Dose Naltrexone comes from a compounding pharmacy and arrives as a liquid, then you're getting pure naltrexone powder dissolved in distilled water. This is probably the " purest " way to ingest naltrexone. You don't need to worry about fillers. BUT -- If you get your LDN in any other form, you're swallowing filler. A " filler " is an inert, inactive ingredient that accompanies every dose of naltrexone you take. If you make your own LDN -- If you make LDN by crushing ReVia (pronounced REV-yah) or another commercially manufactured 50mg naltrexone tablet, you're still ingesting filler, because each tablet is comprised of about 16% Naltrexone and 84% filler. What kind of filler is in your tablet? This depends on the manufacturer. Here are the main manufacturers: Barr Labs – Barr manufactures naltrexone under the brand name ReVia for the US and Canadian markets. This tablet contains 50mg naltrexone and these inactive ingredients: lactose monohydrate, colloidal silicone dioxide, magnesium stearate, crospovidone, microcrystalline cellulose, purified water, Opadry beige (coloring). [information from Barr Labs phone representative.] Bristol Myers Squibb – BMS manufactures naltrexone under the brand name ReVia in markets other than the US and Canada. As of 2002, their 50 mg tablets contain 50 mg of naltrexone hydrochloride, plus these inactive ingredients (filler): lactose, microcrystalline cellulose, crospovidone, silicon dioxide, magnesium stearate, and pale yellow Opadry (colouring). [information from a 2002 leaflet by Australian Prescription Products Guide.] Mallinckrodt – makes a 50mg naltrexone pill called Depade. This tablet contains 50mg naltrexone, plus these inactive ingredients (filler): crospovidone, hydropropyl methylcellulose, lactose monohydrate, magnesium stearate, microcrystalline cellulose, polyethelene glycol, polysorbate 80, silicone dioxide, titanium dioxide, yellow iron oxide, and red iron oxide. [information from Mallinckrodt website.] [Historical Note: The original ReVia was made by Dupont. The inactive ingredients were: lactose, microcrystalline cellulose, crospovidone, silicon dioxide, magnesium stearate, and pale yellow Opadry (colouring). In 2001, Bristol Myers Squibb acquired DuPont Pharmaceuticals. In April 2002, BMS sold the ReVia brand-name rights in the US and Canada to Barr Laboratories. BMS continues to market ReVia outside of the US and Canada.] If your LDN is made by a compounding pharmacy – Ask your pharmacist how it is made. 1. Some compounders make LDN by crushing commercially manufactured 50mg tablets and putting the powder into capsules. Because the amount of powder that goes into each capsule is not enough to fill the capsule, most pharmacies add additional filler. If this is how you get your LDN, you can find out which commercially manufactured tablet is being used and what kind of additional filler is being added. 2. Other compounders don't crush 50mg tablets; instead, they use pure naltrexone powder (purchased in bulk from pharmaceutical companies), which they mix with filler. From these pharmacists, you can learn what kind of filler you are taking. Here are some of the most common fillers used by compounding pharmacists: LACTOSE: Lactose is a naturally-occurring simple carbohydrate, or sugar, found only in the milk of mammals. For this reason, it is also commonly referred to as " milk sugar. " Lactose has long been used as a soluble filler in the manufacture of orally administered pharmaceuticals. It is safe, stable, inexpensive, and has a fast dissolution rate. Pharmaceutical- grade lactose powder is highly pure, and specifically produced to meet government standards of safety and purity. Lactose is easily tolerated by most patients. However, if you are lactose-intolerant (that is, if milk products give you nausea, diarrhea, abdominal cramping, bloating, or flatulence), you might want to try another filler. Note: Dr Bihari asks his patients to use lactose, unless they have an adverse reaction… not because he believes lactose is better than other fillers, but because he began his study of LDN with lactose, and he wants his records to be consistent. ACIDOPHILOUS – (pronounced Ah-SID-uh-FILL-us) – is lactic bacteria, or one-celled micro-organisms, used by the body to promote immunity and proper nutrition. Sold over the counter as a nutritional supplement and digestive aid, Acidophilus is sometimes used as a treatment for diarrhea and constipation. It is commercially available as powder, tablets, capsules or liquid. Lactose-intolerant patients sometimes switch to Acidophilus filler in their LDN capsules. AVICEL – a brand name for microcrystalline cellulose. Avicel has been used safely and effectively for 35 years in the food and pharmaceutical industries. Virtually inert, it is not absorbed into the system, and will not interfere or interact with other nutrients, vitamins or minerals. Avicel is made of wood which has been purified and powdered into extremely tiny particles -- between 0.000039 and 0.0001560 of an inch of pure fiber, with the consistency of a very fine face powder. Avicel is the filler used by Skip's Pharmacy in Boca Raton. For a fun history of Avicel, " Let Us Have Nothing To Eat, " CLICK HERE. CALCIUM CARBONATE – a mineral that occurs naturally in limestone, marble and coral. Crushed to a fine, flavorless, odourless powder, it is a natural food additive, and the most common ingredient in calcium supplements and antacids. Calcium is absorbed by the small intestine and is used by the body to build bone tissue. Calcium supplements are generally well tolerated, but in some patients may cause constipation, bloating, gas and flatulence. People with kidney stones, hypercalcemia, sarcoidosis, hyperparathyroidism, hypervitaminosis D or cancer should not take calcium carbonate. People taking calcium supplements are usually advised to take them with food. There has been some concern among LDN users that calcium carbonate is occasionally packed too tight in the capsule, which can cause a slow-release reaction, rather than the desired fast- release. IMPORTANT: Make sure to specify that you do NOT want LDN in a slow- release form. Reports have been received from patients that their pharmacies have been supplying a slow-release form of naltrexone. Pharmacies should be instructed NOT to provide LDN in an " SR " or slow-release or timed- release form. Unless the low dose of naltrexone is in an unaltered form, which permits it to reach a prompt " spike " in the blood stream, its therapeutic effects may be inhibited. Fillers. Capsules of LDN necessarily contain a substantial percentage of neutral inactive filler. Experiments by the compounding pharmacist, Dr. Skip Lenz, have demonstrated that the use of calcium carbonate as a filler will interfere with absorption of the LDN capsule. Therefore, it is suggested that calcium carbonate filler not be employed in compounding LDN capsules. He recommends either Avicel, lactose (if lactose intolerance is not a problem), or sucrose fillers as useful fast-release fillers. Any questions about filler should be referred to your doctor or your pharmacist. Maarit wrote: > I cannot find the info about what fillings are not good for LDN > capsules???? Can anyone help, please? I got the rx from my doctor > today!!!!!!!!!!!!! > > Maarit > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 28, 2008 Report Share Posted October 28, 2008 IMPORTANT: Make sure to specify that you do NOT want LDN in a slow- release form. Reports have been received from patients that their pharmacies have been supplying a slow-release form of naltrexone. Pharmacies should be instructed NOT to provide LDN in an " SR " or slow-release or timed- release form. Unless the low dose of naltrexone is in an unaltered form, which permits it to reach a prompt " spike " in the blood stream, its therapeutic effects may be inhibited. Fillers. Capsules of LDN necessarily contain a substantial percentage of neutral inactive filler. Experiments by the compounding pharmacist, Dr. Skip Lenz, have demonstrated that the use of calcium carbonate as a filler will interfere with absorption of the LDN capsule. Therefore, it is suggested that calcium carbonate filler not be employed in compounding LDN capsules. He recommends either Avicel, lactose (if lactose intolerance is not a problem), or sucrose fillers as useful fast-release fillers. http://www.low dose naltrexone.org/index.htm#What_is_low_dose_naltrexone > > I cannot find the info about what fillings are not good for LDN > capsules???? Can anyone help, please? I got the rx from my doctor > today!!!!!!!!!!!!! > > Maarit > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 28, 2008 Report Share Posted October 28, 2008 How soon they forget! Art -- > > In particular avoid slow release fillers like calcium carbonate. Apart > from that it's just a matter of personal choice or where you get it > from. For example Skip only uses Avicel so if you use Skip's you have no > choice in the matter (which to 99.5% of people is not an issue). > > Message #71781 posted by Art only days ago says: > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 28, 2008 Report Share Posted October 28, 2008 > > > > In particular avoid slow release fillers like calcium carbonate. > Apart > > from that it's just a matter of personal choice or where you get it > > from. For example Skip only uses Avicel so if you use Skip's you have > no > > choice in the matter (which to 99.5% of people is not an issue). > > > > Message #71781 posted by Art only days ago says: > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 28, 2008 Report Share Posted October 28, 2008 Say what?!! The subject was fillers NOT to be used in LDN capsules. CALCIUM CARBONATE must not be used as a filler as it may cause LDN to be released slowly in ones system. Art -- > > I have a neighbor who has a doctorate in Microbiology and has written > books on health and wellness, was Mr. Universe, has trained body > builders for many years and has done a lot of cancer research as well > as other research. I always consult with him when I have a question > about supplements, etc., and of course I trust him since he is so > qualified in such matters. He says to take Calcium Citrate (liquid). > It is more easily assimilated. -Biz > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 28, 2008 Report Share Posted October 28, 2008 ah, so that is Literally Apples & Oranges! LOL [low dose naltrexone] Re: Fillings!!! Say what?!!The subject was fillers NOT to be used in LDN capsules. CALCIUM CARBONATE must not be used as a filler as it may cause LDN to be released slowly in ones system. Art--> > I have a neighbor who has a doctorate in Microbiology and has written> books on health and wellness, was Mr. Universe, has trained body> builders for many years and has done a lot of cancer research as well> as other research. I always consult with him when I have a question> about supplements, etc., and of course I trust him since he is so> qualified in such matters. He says to take Calcium Citrate (liquid).> It is more easily assimilated. -Biz> > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 29, 2008 Report Share Posted October 29, 2008 > > > > I have a neighbor who has a doctorate in Microbiology and has > written > > books on health and wellness, was Mr. Universe, has trained body > > builders for many years and has done a lot of cancer research as > well > > as other research. I always consult with him when I have a question > > about supplements, etc., and of course I trust him since he is so > > qualified in such matters. He says to take Calcium Citrate (liquid). > > It is more easily assimilated. -Biz > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 29, 2008 Report Share Posted October 29, 2008 Oh dear! Then what about the 50mg naltrexone tablet (a small blue tablet, not capsule) from CCM Pharmaceutical? Have been making my own low dose naltrexone so far. Does that also contain fillings??? HP > > I cannot find the info about what fillings are not good for LDN > > capsules???? Can anyone help, please? I got the rx from my doctor > > today!!!!!!!!!!!!! > > > > Maarit > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 29, 2008 Report Share Posted October 29, 2008 Yes the 50 mg Naltrexone Tablets also contain filler but not sure what kind it has. May there be a miracle in YOUR life today and may you have the EYES to see it.From My Heart to Yours Love, Hugs & Blessings, CrystalLDN_Users Group OwnerDiagnosed November 2004 with Secondary Progressive MS, Transverse Myelitis and an Advocate for LDN!! 3 years on LDN with Skip's Pharmacy.....No Relapses......Crystal's MS,TM & LDN Websitehttp://www.freewebs.com/crystalangel6267/index.htm LDN Website http://ww.ldninfo.org/Crystal's LDN Support GroupLDN_Users/ Crystal's LDN Gift Shophttp://www.cafepress.com/crystalldngifts Skip's Compounding Pharmacyhttp://www.skipspharmacy.com/ From: chu_hui_ping <chu_hui_ping@...>low dose naltrexone Sent: Tuesday, October 28, 2008 8:12:22 PMSubject: [low dose naltrexone] Re: Fillings!!! Oh dear! Then what about the 50mg naltrexone tablet (a small blue tablet, not capsule) from CCM Pharmaceutical? Have been making my own low dose naltrexone so far. Does that also contain fillings???HP> > I cannot find the info about what fillings are not good for LDN> > capsules???? Can anyone help, please? I got the rx from my doctor> > today!!!!!!! !!!!!!> >> > Maarit> >> >> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 29, 2008 Report Share Posted October 29, 2008 The 50mg tablets like Revia apparently contain about 85% filler (composition unknown and probably varies). However, if you are making your own by dissolving the tablet in water the amount of filler you are ingesting each day is very minimal. chu_hui_ping wrote: > Oh dear! Then what about the 50mg naltrexone tablet (a small blue > tablet, not capsule) from CCM Pharmaceutical? Have been making my own > low dose naltrexone so far. Does that also contain fillings??? > > HP Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 29, 2008 Report Share Posted October 29, 2008 If you're making homemade liquid LDN, as this is a very fast release formula, then there's no need to worry about the filler unless you happen to be alergic to that particular filler. Not sure what's in the 50mg tablet. Art -- > > Oh dear! Then what about the 50mg naltrexone tablet (a small blue > tablet, not capsule) from CCM Pharmaceutical? Have been making my own > low dose naltrexone so far. Does that also contain fillings??? > > HP Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 29, 2008 Report Share Posted October 29, 2008 Huiping, good to see you here!:-)) I guess with the ready made tablets the filler will not be quite so important since you are making a dilution which I would say would be more easily absorbed, certainly the liquid Dickson's chemist supplies provides a quicker 'hit' than the capsules. You could though, ask the supplier what filler is in the tablets - out of curiosity..... Best Celia Quote Link to comment Share on other sites More sharing options...
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