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Re: replacement for immodium

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hi marie i do not know if there is other meds,but your post put me in

doubt for this meaning,in this period i'm using immodium for a viral

intestinal infection and dissentery,i'm also getting each day 3 mg

ldn capsule for ms.i did not belive tha getting immodium could be

counterindicated with ldn,but reading your post i'm not so sure it's

wright.do you/or anybody know if it's possible to get immodium

together ldn

my best

emiliano

>

> hi everybody,

> i started ldn over two weeks ago for crohn's. apart from the cold

i

> have found it great. i have a resection where most of my colon is

> gone. the colonoscopy that i had before i started the ldn showed

some

> inflammation in the small intestine. my joints are much better

since i

> started the ldn.

> i stopped taking immodium a few days before i started ldn, and have

> tried Esdifan which i stopped because it has calcium carbonate, and

> now i'm taking zeolyte powder, three heaping teaspoons a day. i've

not

> been having as many fruits and vegetables as i like because it goes

> through me fairly quickly. it's a miracle that the zeolyte is as

good

> as it is. i used to need 3 - 4 immodium a day.

> my question is:Is there any medication, instead of the immodium,

that

> would work with ldn, and that i could use with the zeolyte?

> thank you very much, mary

>

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HI ALL,

REALLY I ALSO BELIVE THAT IMMODIUM IS NOT COUNTERINDICATED WITH LDN.

I WOULD LIKE TO KNOW WHAT'S THE REASON TO CONSIDER IT NOT COMPATIBLE

WITH LDN.

ANY INFORMATION IS WELLCOME.

MY BEST

EMILIANO

>

> HI GROUP - what is the problem with immodium used with LDN??

>

> _marshiris@..._ (mailto:marshiris@...)

>

>

> **************Life should be easier. So should your homepage. Try

the NEW

> AOL.com.

> (http://www.aol.com/?optin=new-

dp & icid=aolcom40vanity & ncid=emlcntaolcom00000002)

>

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Imodium is a brand of loperamide. Perhaps it does not interfere with

the action of LDN in the brain. Maybe the answer to the question of

using it with LDN is in this Wikipedia article:

Mode of action

Loperamide is an opioid receptor agonist and acts on the & #956;-opioid

receptors in the myenteric plexus large intestines; it does not affect

the central nervous system like other opioids.

It works by decreasing the activity of the myenteric plexus which

decreases the motility of the circular and longitudinal smooth muscles

of the intestinal wall. This increases the amount of time substances

stay in the intestine, allowing for more water to be absorbed out of

the fecal matter. Loperamide also decreases colonic mass movements and

suppresses the gastrocolic reflex.[4]

Loperamide molecules do not cross the blood-brain barrier in

significant amounts, and thus it has no analgesic properties. Any that

do cross the blood-brain barrier are quickly exported from the brain

by P-glycoprotein (Pgp), also known as multidrug resistance protein

(MDR1). Tolerance in response to long-term use has not been reported.

However, loperamide can cause physical dependence. Symptoms of opiate

withdrawal have been observed in patients abruptly discontinuing

long-term therapy with loperamide. For this reason, the drug was

briefly classified as a Schedule V controlled substance upon its

introduction.[

Konnie

> >

> > HI GROUP - what is the problem with immodium used with LDN??

> >

> > _marshiris@_ (mailto:marshiris@)

> >

> >

> > **************Life should be easier. So should your homepage. Try

> the NEW

> > AOL.com.

> > (http://www.aol.com/?optin=new-

> dp & icid=aolcom40vanity & ncid=emlcntaolcom00000002)

> >

>

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I asked both my regular pharmacist and my compounding pharmacist (for

LDN) and they both said that Imodium is fine with LDN but Lomotil is a

synthetic opioid and MIGHT cancel the effects of

LDN. If I am having a particularly bad day, I will resort to

Lomotil, only during the day time so that it is out of my system before I

take the LDN at 10:00 pm.

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