Re: LDN & RT3 - finding ANY scientific info on rT3?

November 14, 2008

On Nov 14, 2008, at 12:40 PM, free2ridejones wrote:

> Is LDN any good for those with high RT3?

>

Not specifically related to LDN and rT3 (I assume reverse-T3

dominant thyroid problems?), but does anyone know where I can find

scientific backing for the phenomenon on rT3 dominance? It's

generally accepted as a " factoid " that rT3 will compete with T3 for

the T3 receptor, but all the scientific papers I've found

specifically say that rT3 is biologically inactive (implying non-

binding as well). The Wikipedia article states that it binds the

T3r, but doesn't cite anything. 's temperature syndrome is

based on this, as well as I assume interactions between high rT3 and

the de-iodinase enzyme family, but doesn't cite anything..

A related thing to this is the fact that people actually feel

better when their temperature is at 98.6 for most of the day (basal

98.0+-0.1 per ). Someone asked a question the the WTS email

letter about the idea that " actual " body temperature isn't 98.6, but

actually 98.2 - and that 98.6 was measured 100 years ago on an

inaccurate thermometer, etc - a story I've heard (I don't know what

to think). Dr. 's response was that " most people feel better

at 98.6. " That's fine, *if you believe anecdotal evidence*. I can't

find ANYTHING speaking to multiple enzyme dysfunction. I do have

' 1942 JAMA article on basal temperature and basal metabolism,

but it again it essentially a collection of " anecdotes " (this alone

shows how much medicine has changed in the past 60 years - I don't

think an article like that would even get published today in JAMA!)

Meanwhile, all of us are seemingly surrounded by relative idiots

who won't believe *people's experiences*, but only that Oh-So-Holy

" clinical evidence " (on LDN, autism and vaccines, autism treatment,

low temperature, thyroid symptoms that still persist even when TSH is

'fine', etc, etc) It's absolutely maddening - and I wonder in the

long term how you possibly deal with people who won't listen to

empirical evidence - no matter how much of it there is?

Jim

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