Gel to block HIV like a condom

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Dear Forum,

Scientists have created a gel that could prevent the transmission of HIV by

physically stopping the virus in its tracks.

The 'molecular condom' was designed by scientists at the University of Utah in

the United States. If it passes clinical trials, it will enable women to protect

themselves against HIV without approval from their partners.

Kiser, assistant professor of bioengineering at the University of Utah,

says the gel would act in a similar way to a condom. Women would insert it

before intercourse and the acidic conditions of the vagina would ensure it

remained liquid, allowing it to coat the vaginal walls and therefore the cells

vulnerable to HIV infection.

The presence of semen makes the vagina less acidic, and it is expected that this

change in pH will cause the molecules within the gel to interact and turn

semisolid. The resulting mesh would be so small, virus particles would be unable

to penetrate.

Unlike existing microbicides, Kiser's molecular condom appears not to be

affected by high temperatures, making it potentially suitable for use in hot

developing countries.

A paper describing the HIV-blocking properties of the gel was published in

Advanced Functional Materials on 10 August 2009.

Dr. Anil Pratap Singh,

HIV/AIDS Consultant &

Secretary & CEO,

Global Science Academy,

Satyawanpury,

Block Road, Basti-272 001(Uttar Pradesh) INDIA,

Tel.Nos.:+91 5542 287060, 247186

Fax No.: +91 5542 247186

Mobile No.: 9336785696,

Email: globalaps@... / global_aps@...

Websites: www.gsaindia.org.in, www.ngogateway.org/gsa