Medical Hypotheses Article - LDN for disease prevention and quality of life

[Guest guest]

Hello everyone,

The below is an excellent summary of a recently published article in Medical Hypothesis. If you are having trouble with a doctor understanding LDN, you may want to consider getting the full text of the article and giving it to your doctor. The article is 3 pages long (which is not too long and gets to the point, while still providing the necessary medical documentation). The article discusses the following topics and also provides 63 referenced materials to support its conclusions:

Introduction

Hypotheses

The Immune and Endorphin Systems,

The beta-endorphin pathway in immune regulation,

Naltrexone modulation of immune regulation and treatment in autoimmune disease,

LDN may work through methione-enkephalin as well

Naltrexone's potential for cancer prevention and treatment

Conclusion

Enjoy ~~ Joyce

Here's the link to the NIH/National Library of Medicine/PUBMed abstract: http://www.ncbi.nlm.nih.gov/pubmed/19041189

Med Hypotheses. 2008 Nov 26. [Epub ahead of print] Links

Low-dose naltrexone for disease prevention and quality of life.

Brown N, Panksepp J.

Department of Humanities and Social Sciences, Embry-Riddle Aeronautical University, Daytona Beach, FL 32114, United States.

The use of low-dose naltrexone (LDN) for the treatment and prophylaxis of various bodily disorders is discussed. Accumulating evidence suggests that LDN can promote health supporting immune-modulation which may reduce various oncogenic and inflammatory autoimmune processes. Since LDN can upregulate endogenous opioid activity, it may also have a role in promoting stress resilience, exercise, social bonding, and emotional well-being, as well as amelioration of psychiatric problems such a autism and depression. It is proposed that LDN can be used effectively as a buffer for a large variety of bodily and mental ailments through its ability to beneficially modulate both the immune system and the brain neurochemistries that regulate positive affect.

PMID: 19041189 [PubMed - as supplied by publisher]

[Guest guest]

That's superb!!

Does any one here have access to the original article? It should go

into the appendix and everyone should bring it to recalcitrant MDs.

Well done, Joyce!

>

>

> Hello everyone,

>

> The below is an excellent summary of a recently published article

> in Medical Hypothesis. If you are having trouble with a doctor

> understanding LDN, you may want to consider getting the full text of the

> article and giving it to your doctor. The article is 3 pages long

> (which is not too long and gets to the point, while still providing the

> necessary medical documentation). The article discusses the following

> topics and also provides 63 referenced materials to support its

> conclusions:

>

> * Introduction * Hypotheses * The Immune and Endorphin

Systems,

> * The beta-endorphin pathway in immune regulation, * Naltrexone

> modulation of immune regulation and treatment in autoimmune disease,

> * LDN may work through methione-enkephalin as well * Naltrexone's

> potential for cancer prevention and treatment * Conclusion

>

> Enjoy ~~ Joyce

>

>

>

> Here's the link to the NIH/National Library of Medicine/PUBMed

> abstract: http://www.ncbi.nlm.nih.gov/pubmed/19041189

> <http://www.ncbi.nlm.nih.gov/pubmed/19041189>

>

>

>

> Med Hypotheses. 2008 Nov 26. [Epub ahead of print] [Click here to read]

>

<http://www.ncbi.nlm.nih.gov/entrez/utils/fref.fcgi?PrId=3048 & itool=Abst\

>

ractPlus-def & uid=19041189 & db=pubmed & url=http://linkinghub.elsevier.com/r\

> etrieve/pii/S0306-9877(08)00507-0> Links

> Low-dose naltrexone for disease prevention and quality of life. Brown N

>

<http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed & Cmd=Search & Term=%22B\

>

rown%20N%22%5BAuthor%5D & itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_Result\

> sPanel.Pubmed_DiscoveryPanel.Pubmed_RVAbstractPlus> , Panksepp J

>

<http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed & Cmd=Search & Term=%22P\

>

anksepp%20J%22%5BAuthor%5D & itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_Res\

> ultsPanel.Pubmed_DiscoveryPanel.Pubmed_RVAbstractPlus> .

> Department of Humanities and Social Sciences, Embry-Riddle Aeronautical

> University, Daytona Beach, FL 32114, United States.

>

> The use of low-dose naltrexone (LDN) for the treatment and prophylaxis

> of various bodily disorders is discussed. Accumulating evidence suggests

> that LDN can promote health supporting immune-modulation which may

> reduce various oncogenic and inflammatory autoimmune processes. Since

> LDN can upregulate endogenous opioid activity, it may also have a role

> in promoting stress resilience, exercise, social bonding, and emotional

> well-being, as well as amelioration of psychiatric problems such a

> autism and depression. It is proposed that LDN can be used effectively

> as a buffer for a large variety of bodily and mental ailments through

> its ability to beneficially modulate both the immune system and the

> brain neurochemistries that regulate positive affect.

>

> PMID: 19041189 [PubMed - as supplied by publisher]

>

[Guest guest]

Thank you, thank you, Thank you, Joyce, this is wonderful!

:-) (And a happy new year to you and your family! :-)Ingrid

From: hope4joyce <hope4joyce@...>low dose naltrexone Sent: Friday, December 19, 2008 5:12:01 AMSubject: [low dose naltrexone] Medical Hypotheses Article - LDN for disease prevention and quality of life

Hello everyone,

The below is an excellent summary of a recently published article in Medical Hypothesis. If you are having trouble with a doctor understanding LDN, you may want to consider getting the full text of the article and giving it to your doctor. The article is 3 pages long (which is not too long and gets to the point, while still providing the necessary medical documentation). The article discusses the following topics and also provides 63 referenced materials to support its conclusions:

Introduction Hypotheses The Immune and Endorphin Systems,

The beta-endorphin pathway in immune regulation, Naltrexone modulation of immune regulation and treatment in autoimmune disease, LDN may work through methione-enkephalin as well Naltrexone's potential for cancer prevention and treatment Conclusion

Enjoy ~~ Joyce

Here's the link to the NIH/National Library of Medicine/PUBMed abstract: http://www.ncbi.nlm.nih.gov/pubmed/19041189

Med Hypotheses. 2008 Nov 26. [Epub ahead of print] Links

Low-dose naltrexone for disease prevention and quality of life.

Brown N, Panksepp J.

Department of Humanities and Social Sciences, Embry-Riddle Aeronautical University, Daytona Beach, FL 32114, United States.

The use of low-dose naltrexone (LDN) for the treatment and prophylaxis of various bodily disorders is discussed. Accumulating evidence suggests that LDN can promote health supporting immune-modulation which may reduce various oncogenic and inflammatory autoimmune processes. Since LDN can upregulate endogenous opioid activity, it may also have a role in promoting stress resilience, exercise, social bonding, and emotional well-being, as well as amelioration of psychiatric problems such a autism and depression. It is proposed that LDN can be used effectively as a buffer for a large variety of bodily and mental ailments through its ability to beneficially modulate both the immune system and the brain neurochemistries that regulate positive affect.

PMID: 19041189 [PubMed - as supplied by publisher]

[Guest guest]

>

> Thank you, thank you, Thank you, Joyce, this is wonderful!

>

>  :-) (And a happy new year to you and your family! :-)Ingrid

>

>

> HI ;

I also thought this was a good summary, but I was not able to open

the 3 page detailed info to present to my Doctor.

Any suggestions would be helpful.I clicked on many of the links but

to no avail.

Marla

thank you

>

> ________________________________

> From: hope4joyce <hope4joyce@...>

> low dose naltrexone

> Sent: Friday, December 19, 2008 5:12:01 AM

> Subject: [low dose naltrexone] Medical Hypotheses Article - LDN for

disease prevention and quality of life

>

>

> Hello everyone,

>       The below is an excellent summary of a recently published

article in Medical Hypothesis.  If you are having trouble with a

doctor understanding LDN, you may want to consider getting the full

text of the article and giving it to your doctor.  The article is 3

pages long (which is not too long and gets to the point, while still

providing the necessary medical documentation).  The article

discusses the following topics and also provides 63 referenced

materials to support its conclusions:

> * Introduction

> * Hypotheses

> * The Immune and Endorphin Systems,

> * The beta-endorphin pathway in immune regulation,

> * Naltrexone modulation of immune regulation and treatment in

autoimmune disease,

> * LDN may work through methione-enkephalin as well

> * Naltrexone's potential for cancer prevention and treatment

> * Conclusion

>       Enjoy ~~ Joyce

>  

>      Here's the link to the NIH/National Library of Medicine/PUBMed

abstract: http://www.ncbi.nlm.nih.gov/pubmed/19041189

>  

> Med Hypotheses. 2008 Nov 26. [Epub ahead of print] Links

> Low-dose naltrexone for disease prevention and quality of life.

> Brown N, Panksepp J..

> Department of Humanities and Social Sciences, Embry-Riddle

Aeronautical University, Daytona Beach, FL 32114, United States.

> The use of low-dose naltrexone (LDN) for the treatment and

prophylaxis of various bodily disorders is discussed. Accumulating

evidence suggests that LDN can promote health supporting immune-

modulation which may reduce various oncogenic and inflammatory

autoimmune processes. Since LDN can upregulate endogenous opioid

activity, it may also have a role in promoting stress resilience,

exercise, social bonding, and emotional well-being, as well as

amelioration of psychiatric problems such a autism and depression. It

is proposed that LDN can be used effectively as a buffer for a large

variety of bodily and mental ailments through its ability to

beneficially modulate both the immune system and the brain

neurochemistries that regulate positive affect.

> PMID: 19041189 [PubMed - as supplied by publisher]

>        

>