Question about Italy study for PPMS

[Guest guest]

I picked up a copy of this study [Multiple Sclerosis 2008; 14: 1076-1083 A pilot trial of low-dose naltrexone in primary progressive multiple sclerosis] last night at the medical library at the University of Utah. I have a few questions that someone here may provide insight about:

In the study, they report a mean age of onset as 40.8 (SD 8.9) and a mean age at enrollment of 53.4 (SD 8.0). This seems rather old for MS. I had thought that the mean age for diagnosis with RRMS is closer to 31. I could understand a more advanced age better if the study had been done on people with SPMS. Are these ages typical of people diagnosed with PPMS?

I found it interesting that the study seemed to add some evidence to the theory that LDN boosts ß-endorphins (BE)

Kennard1319 Buccaneer DrSalt Lake City, UT 84116(801)951-1392www.nathankennard.com

[Guest guest]

They are more typical of people with my condition: PRMS.

But if LDN worked for older people, you can be sure it will work even

better for younger people.

It's the most important study to date done on LDN & MS. I recommend

all MS patients to bring a copy of the abstract to their doctor when

requesting a prescription.

>

> I picked up a copy of this study [Multiple Sclerosis 2008; 14:

1076-1083 A pilot trial of low-dose naltrexone

> in primary progressive multiple sclerosis] last night at the medical

library at the University of Utah. I have a few questions that someone

here may provide insight about:

>

> In the study, they report a mean age of onset as 40.8 (SD 8.9) and a

mean age at enrollment of 53.4 (SD 8.0). This seems rather old for MS.

I had thought that the mean age for diagnosis with RRMS is closer to

31. I could understand a more advanced age better if the study had

been done on people with SPMS. Are these ages typical of people

diagnosed with PPMS?

>

> I found it interesting that the study seemed to add some evidence to

the theory that LDN boosts ß-endorphins (BE)

>

> Kennard

> 1319 Buccaneer Dr

> Salt Lake City, UT 84116

> (801)951-1392

> www.nathankennard.com

>