Re: Starting LDN - side effects with Chron's?

[Guest guest]

Hi Crystal:

Hope all is going well with you. I last wrote to you early last week regarding the list of doctors in Florida. I did call all the doctors in South Florida. Last Thurs. I went to Palm Beach Gardens and saw a very nice doctor there. Was given a prescription for LDN and now have 1.5 mg capsules. Then I will bring it up to 3.mg. then 4.5mg. Skip's in Boca Raton filled the prescription.

Since I've had a bad cold I haven't started yet. I wanted to wait to get rid of the cold and get extra sleep etc. Since you wrote about side effects for MS what side effects might I expect having Chron's? Will I see any response to the drug at 1.5mg or 3.0mg. or have to wait to get to 4.5 mg to get any response? Any info you or people from the group that have experienced first hand using LDN for Chron's will be much appreciated.

Best,

From: Crystals MS TM LDN Website <angelindisguise67@...>Subject: Re: [low dose naltrexone] Starting LDN - side effects - what to do?low dose naltrexone Date: Tuesday, November 25, 2008, 5:34 PM

Introductory Side-effects: There may be some initial transient, though temporary, increase in MS symptoms during the adaptive period when the LDN is first introduced. This usually lasts no more than one week but if symptoms are severe, or more prolonged, then the initial dose of 1.5 for a month, 3 for a month, then 4.5 until the anticipated improvements begin to develop.

Introductory symptoms, on starting this treatment, may include such as disturbed sleep, occasionally with vivid, bizarre and disturbing dreams, tiredness, fatigue, spasm and pain.

Symptoms related to increased endorphins: These may include such as nausea or constipation. These symptoms diminish naturally as the body adjusts to the increased endorphin level.

Symptoms related to previous Opiate use: On starting LDN the recent use of opiate analgesics will result in an opiate withdrawal syndrome, with increased pain, spasm, vomiting and diarrhea. These symptoms may be prevented by stopping all opiate analgesics at least two weeks before starting the LDN.

Introductory LDN Symptoms

For those of you in the first 3 months of LDN therapy Dr. Bob Lawrence from the UK who has MS & uses LDN himself explains why the temporary increase in MS symptoms.When starting this LDN (Low Dose Naltrexone) therapy in the treatment of MS, there may also be some initial transient, though temporary, increase in MS symptoms. Experience in using this method has demonstrated most commonly, such as disturbed sleep, occasionally with vivid, bizarre and disturbing dreams, tiredness, fatigue, spasm and pain. These increased symptoms would not normally be expected to last more than seven to ten days.Rarely, other transient symptoms have included more severe pain and spasm, headache, diarrhea or vomiting. These additional symptoms would appear to be associated with the previous frequent use of strong analgesics, which effectively create an addiction and dependency, thus increasing

the body's sensitivity to pain. This temporary increase in symptoms may also perhaps be explained when we consider the manner in which this drug is expected to work.Initially, MS occurs due to a reduction in the activity of the controlling influence of the suppressor T-cells within the immune system. During an acute relapse, the overall number of T-cells is reduced, the normal balance of helper T-cells and suppressor T-cells is disrupted and the damaging helper (CD-4) T-cells tend to predominate. This is the situation most pronounced during an acute relapse but occurs similarly, but to a lesser extent, in chronic progressive MS. Under the influence of LDN there will be an expected increase in the overall numbers of T-cells but, because the CD-4, helper T-cells tend to predominate at this time, an increase in their numbers will expectedly tend to increase MS symptoms. It is only when the numbers of

suppressor T-cells effectively "catch up" that the normal balance is restored and symptoms once again diminish and improve. In addition, because LDN stimulates the immune system and many of the drugs routinely used by the NHS in the treatment of MS further suppress the immune system, LDN cannot be used in company with steroids, beta interferon, methotrexate, azathioprine or mitozantrone or any other immune suppressant drug. If there is any doubt, please submit a full list of the drugs you are presently taking so that their compatibility may be assessed. In addition, because LDN will also block the analgesic effects of any opiate drugs (includes codeine, dihydrocodeine, morphine, pethidine or diamorphine) presently being taken, the use of LDN will initially greatly increase the level of pain experienced. It is therefore advisable that any opiate-like drugs be discontinued at least two weeks before

this treatment is initiated. When starting the treatment it is essential that any untoward or adverse side-effects are reported immediately so that the treatment process can be further assessed and, if necessary, modified. Dr. M R Lawrence

May there be a miracle in YOUR life today and may you have the EYES to see it.From My Heart to Yours Love, Hugs & Blessings, CrystalLDN_Users Group OwnerDiagnosed November 2004 with Secondary Progressive MS, Transverse Myelitis and an Advocate for LDN!! 3 years on LDN with Skip's Pharmacy.... .No Relapses.... .Crystal's MS,TM & LDN Websitehttp://www.freewebs .com/crystalange l6267/index. htm LDN Website http://ww.ldninfo.

org/Crystal's LDN Support Grouphttp://health. groups.. com/group/ LDN_Users/ Crystal's LDN Gift Shophttp://www.cafepres s.com/crystalldn gifts Skip's Compounding Pharmacyhttp://www.skipspha rmacy.com/

From: renatatrawinski <rtrawinskitelus (DOT) net>low dose naltrexoneSent: Tuesday, November 25, 2008 1:37:11 PMSubject: [low dose naltrexone] Starting LDN - side effects - what to do?

Hello,I am new to this group and see a wealth of wisdom, so I am hoping you can help me a little as I journey into the LDN treatment. Thank you in advance for your time. I have undiagnosed neurological symptoms (4 years) with a high possibility of them to be MS. My neurologist wants to wait and see, but the symptoms are increasing and I would like to take an active approach and help myself asap. With that I have attended an LDN Conference in L.A. on October 11 and immediately following this conference, on Oct. 17 I have started with 1.5 mg of LDN. Had no side effects and no improvements. A month later, on Nov. 16, I have gone to 3 mg of LDN and four days after increasing my dose I began experiencing some symptoms which are not listed in the common side effects. I have had three nights of abdominal pain, nausea and cramps followed by a very loose stool and a great urgency to go to

the bathroom. Also some blood spotting and great urgency to urinate. Now my bowel is getting better, but the urgency to urinate is increasing. The abdominal pain, slight nausea and crapms come and go. I am not sure what to do. i get my LDN from Skip's Pharmacy with Avicel filler. Any advice would be greatly appreciated. Have you heard of these type of symptoms while starting LDN? Should I keep taking 3 mg and see what happens? Please help.Warmly,RT

[Guest guest]

Hi Crystal:

Hope all is going well with you. I last wrote to you early last week

regarding the list of doctors in Florida. I did call all the doctors

in South Florida. Last Thurs. I went to Palm Beach Gardens and saw a

very nice doctor there. Was given a prescription for LDN and now

have 1.5 mg capsules. Then I will bring it up to 3.mg. then 4.5mg.

Skip's in Boca Raton filled the prescription.

Since I've had a bad cold I haven't started yet. I wanted to wait to

get rid of the cold and get extra sleep etc. Since you wrote about

side effects for MS what side effects might I expect having Chron's?

Will I see any response to the drug at 1.5mg or 3.0mg. or have to

wait to get to 4.5 mg to get any response? Any info you or people

from the group that have experienced first hand using LDN for

Chron's will be much appreciated.

Best,

>

> Introductory Side-effects:There may be some initial transient,

though temporary, increase in MS symptoms during the adaptive period

when the LDN is first introduced.  This usually lasts no more than

one week but if symptoms are severe, or more prolonged, then the

initial dose of 1.5 for a month, 3 for a month, then 4.5until the

anticipated improvements begin to develop.

>  

> Introductory symptoms, on starting this treatment, may include such

as disturbed sleep, occasionally with vivid, bizarre and disturbing

dreams, tiredness, fatigue, spasm and pain. 

>  

> Symptoms related to increased endorphins:These may include such as

nausea or constipation.  These symptoms diminish naturally as the

body adjusts to the increased endorphin level.

>  

> Symptoms related to previous Opiate use:On starting LDN the recent

use of opiate analgesics will result in an opiate withdrawal

syndrome, with increased pain, spasm, vomiting and diarrhea.  These

symptoms may be prevented by stopping all opiate analgesics at least

two weeks before starting the LDN.

>  

>  

>  

>  

> Introductory LDN Symptoms

>  

>  

> For those of you in the first 3 months of LDN therapy Dr. Bob

> Lawrence from the UK who has MS & uses LDN himself explains why the

temporary increase in MS symptoms.

>

> When starting this LDN (Low Dose Naltrexone) therapy in the

treatment of MS, there may also be some initial transient, though

temporary, increase in MS symptoms.

>

> Experience in using this method has demonstrated most commonly,

such as disturbed sleep, occasionally with vivid, bizarre and

disturbing

> dreams, tiredness, fatigue, spasm and pain. These increased

symptoms

> would not normally be expected to last more than seven to ten days.

>

> Rarely, other transient symptoms have included more severe pain and

> spasm, headache, diarrhea or vomiting. These additional symptoms

> would appear to be associated with the previous frequent use of

> strong analgesics, which effectively create an addiction and

> dependency, thus increasing the body's sensitivity to pain. This

> temporary increase in symptoms may also perhaps be explained when

we consider the manner in which this drug is expected to work.

>

> Initially, MS occurs due to a reduction in the activity of the

> controlling influence of the suppressor T-cells within the immune

> system. During an acute relapse, the overall number of T-cells is

> reduced, the normal balance of helper T-cells and suppressor T-

cells

> is disrupted and the damaging helper (CD-4) T-cells tend to

> predominate. This is the situation most pronounced during an acute

> relapse but occurs similarly, but to a lesser extent, in chronic

> progressive MS. Under the influence of LDN there will be an

expected

> increase in the overall numbers of T-cells but, because the CD-4,

> helper T-cells tend to predominate at this time, an increase in

their

> numbers will expectedly tend to increase MS symptoms. It is only

when the numbers of suppressor T-cells effectively " catch up " that

the

> normal balance is restored and symptoms once again diminish and

> improve.

>

> In addition, because LDN stimulates the immune system and many of

the drugs routinely used by the NHS in the treatment of MS further

> suppress the immune system, LDN cannot be used in company with

> steroids, beta interferon, methotrexate, azathioprine or

mitozantrone

> or any other immune suppressant drug. If there is any doubt, please

> submit a full list of the drugs you are presently taking so that

> their compatibility may be assessed. In addition, because LDN will

> also block the analgesic effects of any opiate drugs (includes

> codeine, dihydrocodeine, morphine, pethidine or diamorphine)

> presently being taken, the use of LDN will initially greatly

increase

> the level of pain experienced. It is therefore advisable that any

> opiate-like drugs be discontinued at least two weeks before this

> treatment is initiated. When starting the treatment it is essential

> that any untoward or adverse side-effects are reported immediately

so

> that the treatment process can be further assessed and, if

necessary,

> modified.

>

> Dr. M R Lawrence

>  

>

>  May there be a miracle in YOUR life today and may you have the

EYES to see it.

>

> From My Heart to Yours

> Love, Hugs & Blessings,

> Crystal

> LDN_Users Group Owner

>

> Diagnosed November 2004 with Secondary Progressive MS, Transverse

Myelitis and an Advocate for LDN!! 3 years on LDN with Skip's

Pharmacy.....No Relapses.....

>

>

> Crystal's MS,TM & LDN Website

> http://www.freewebs.com/crystalangel6267/index.htm

>

> LDN Website

> http://ww.ldninfo.org/

>

> Crystal's LDN Support Group

> LDN_Users/

>

> Crystal's LDN Gift Shop

> http://www.cafepress.com/crystalldngifts

>

> Skip's Compounding Pharmacy

> http://www.skipspharmacy.com/

>  

>

>

>

>

> ________________________________

> From: renatatrawinski <rtrawinski@...>

> low dose naltrexone

> Sent: Tuesday, November 25, 2008 1:37:11 PM

> Subject: [low dose naltrexone] Starting LDN - side effects - what to

do?

>

>

> Hello,

>

> I am new to this group and see a wealth of wisdom, so I am hoping

> you can help me a little as I journey into the LDN treatment. Thank

> you in advance for your time.

>

> I have undiagnosed neurological symptoms (4 years) with a high

> possibility of them to be MS. My neurologist wants to wait and see,

> but the symptoms are increasing and I would like to take an active

> approach and help myself asap. With that I have attended an LDN

> Conference in L.A. on October 11 and immediately following this

> conference, on Oct. 17 I have started with 1.5 mg of LDN.. Had no

> side effects and no improvements. A month later, on Nov. 16, I have

> gone to 3 mg of LDN and four days after increasing my dose I began

> experiencing some symptoms which are not listed in the common side

> effects. I have had three nights of abdominal pain, nausea and

> cramps followed by a very loose stool and a great urgency to go to

> the bathroom. Also some blood spotting and great urgency to

urinate.

> Now my bowel is getting better, but the urgency to urinate is

> increasing. The abdominal pain, slight nausea and crapms come and

> go. I am not sure what to do. i get my LDN from Skip's Pharmacy

with

> Avicel filler. Any advice would be greatly appreciated. Have you

> heard of these type of symptoms while starting LDN? Should I keep

> taking 3 mg and see what happens? Please help.

>

> Warmly,

> RT

>

[Guest guest]

Taking LDN now may help you get rid of your cold sooner.

You should start tonight.

Art

--

>

> Hi Crystal:

>

> Hope all is going well with you. I last wrote to you early last

week

> regarding the list of doctors in Florida. I did call all the

doctors

> in South Florida. Last Thurs. I went to Palm Beach Gardens and saw

a

> very nice doctor there. Was given a prescription for LDN and now

> have 1.5 mg capsules. Then I will bring it up to 3.mg. then 4.5mg.

> Skip's in Boca Raton filled the prescription.

>

> Since I've had a bad cold I haven't started yet. I wanted to wait

to

> get rid of the cold and get extra sleep etc. Since you wrote

about

> side effects for MS what side effects might I expect having

Chron's?

> Will I see any response to the drug at 1.5mg or 3.0mg. or have to

> wait to get to 4.5 mg to get any response? Any info you or people

> from the group that have experienced first hand using LDN for

> Chron's will be much appreciated.

>

> Best,

>

>