4.5 ldn

[Guest guest]

Hi,

Went up to 4.5 LDN past 2 nights. My husband says I have been

screaming out loud in a concerned way while sleeping. I have

absolutely no recollection of this and I feel I am sleeping fine. He

is a little concerned but not too bothered. He just says he doesn't

know if he should wake me up.. This too shall pass, right?

I feel awful waking him up and him getting so concerned about me.

Thanks,

Jodi

[Guest guest]

Introductory Side-effects: There may be some initial transient, though temporary, increase in MS symptoms during the adaptive period when the LDN is first introduced. This usually lasts no more than one week but if symptoms are severe, or more prolonged, then the initial dose of 1.5 for a month, 3 for a month, then

4.5 until the anticipated improvements begin to develop.

Introductory symptoms, on starting this treatment, may include such as disturbed sleep, occasionally with vivid, bizarre and disturbing dreams, tiredness, fatigue, spasm and pain.

Symptoms related to increased endorphins: These may include such as nausea or constipation. These symptoms diminish naturally as the body adjusts to the increased endorphin level.

Symptoms related to previous Opiate use: On starting LDN the recent use of opiate analgesics will result in an opiate withdrawal syndrome, with increased pain, spasm, vomiting and diarrhea. These symptoms may be prevented by stopping all opiate analgesics at least two weeks before starting the LDN.

Introductory LDN Symptoms

For those of you in the first 3 months of LDN therapy Dr. Bob Lawrence from the UK who has MS & uses LDN himself explains why the temporary increase in MS symptoms.When starting this LDN (Low Dose Naltrexone) therapy in the treatment of MS, there may also be some initial transient, though temporary, increase in MS symptoms. Experience in using this method has demonstrated most commonly, such as disturbed sleep, occasionally with vivid, bizarre and disturbing dreams, tiredness, fatigue, spasm and pain. These increased symptoms would not normally be expected to last more than seven to ten days.Rarely, other transient

symptoms have included more severe pain and spasm, headache, diarrhea or vomiting. These additional symptoms would appear to be associated with the previous frequent use of strong analgesics, which effectively create an addiction and dependency, thus increasing the body's sensitivity to pain. This temporary increase in symptoms may also perhaps be explained when we consider the manner in which this drug is expected to work.Initially, MS occurs due to a reduction in the activity of the controlling influence of the suppressor T-cells within the immune system. During an acute relapse, the overall number of T-cells is reduced, the normal balance of helper T-cells and suppressor T-cells is disrupted and the damaging helper (CD-4) T-cells tend to predominate. This is the situation most pronounced during an acute relapse but occurs similarly, but to a lesser extent, in chronic progressive MS. Under the

influence of LDN there will be an expected increase in the overall numbers of T-cells but, because the CD-4, helper T-cells tend to predominate at this time, an increase in their numbers will expectedly tend to increase MS symptoms. It is only when the numbers of suppressor T-cells effectively "catch up" that the normal balance is restored and symptoms once again diminish and improve. In addition, because LDN stimulates the immune system and many of the drugs routinely used by the NHS in the treatment of MS further suppress the immune system, LDN cannot be used in company with steroids, beta interferon, methotrexate, azathioprine or mitozantrone or any other immune suppressant drug. If there is any doubt, please submit a full list of the drugs you are presently taking so that their compatibility may be assessed. In addition, because LDN will also block the analgesic effects of any opiate drugs

(includes codeine, dihydrocodeine, morphine, pethidine or diamorphine) presently being taken, the use of LDN will initially greatly increase the level of pain experienced. It is therefore advisable that any opiate-like drugs be discontinued at least two weeks before this treatment is initiated. When starting the treatment it is essential that any untoward or adverse side-effects are reported immediately so that the treatment process can be further assessed and, if necessary, modified. Dr. M R Lawrence

May there be a miracle in YOUR life today and may you have the EYES to see it.From My Heart to Yours Love, Hugs & Blessings, CrystalLDN_Users Group OwnerDiagnosed November 2004 with Secondary Progressive MS, Transverse Myelitis and an Advocate for LDN!! 3 years on LDN with Skip's Pharmacy.....No Relapses.....Crystal's MS,TM & LDN Websitehttp://www.freewebs.com/crystalangel6267/index.htm LDN Website http://ww.ldninfo.org/Crystal's LDN Support GroupLDN_Users/ Crystal's LDN Gift Shophttp://www.cafepress.com/crystalldngifts Skip's Compounding Pharmacyhttp://www.skipspharmacy.com/

From: jodah235 <jodah235@...>low dose naltrexone Sent: Saturday, December 6, 2008 12:45:54 PMSubject: [low dose naltrexone] 4.5 ldn

Hi,Went up to 4.5 LDN past 2 nights. My husband says I have beenscreaming out loud in a concerned way while sleeping. I haveabsolutely no recollection of this and I feel I am sleeping fine. Heis a little concerned but not too bothered. He just says he doesn'tknow if he should wake me up.. This too shall pass, right?I feel awful waking him up and him getting so concerned about me.Thanks,Jodi

[Guest guest]

I'm quite convinced that you have had one of the famous side effects "vivid dreams", but it has obviously not been too vivid to wake you up, but enough to wake your husband up.

As you say: This too shall pass :-)

Continue to have success with LDN, ok? ;-)

Ingrid

From: jodah235 <jodah235@...>low dose naltrexone Sent: Saturday, December 6, 2008 6:45:54 PMSubject: [low dose naltrexone] 4.5 ldnHi,Went up to 4.5 LDN past 2 nights. My husband says I have beenscreaming out loud in a concerned way while sleeping. I haveabsolutely no recollection of this and I feel I am sleeping fine. Heis a little concerned but not too bothered. He just says he doesn'tknow if he should wake me up.. This too shall pass, right?I feel awful waking him up and him getting so concerned about me.Thanks,Jodi------------------------------------