Guest guest Posted December 4, 2008 Report Share Posted December 4, 2008 Hi all, I bought some Ginkgo Biloba today, 2000mg. I had previously read that it increases blood flow to the brain?..I've no idea how much to give though, and how many times through day to give? Ds is 17kg(37lbs). Is this one of those supps that needs to be increased to watch for side effects? Donna. Start your day with 7 and win a Sony Bravia TV. Enter now http://au.docs./homepageset/?p1=other & p2=au & p3=tagline Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 4, 2008 Report Share Posted December 4, 2008 > > > Hi all, > I bought some Ginkgo Biloba today, 2000mg. > I had previously read that it increases blood flow to the brain?..I've no idea how much to give though, and how many times through day to give? > Ds is 17kg(37lbs). Is this one of those supps that needs to be increased to watch for side effects? > Donna. > > > Start your day with 7 and win a Sony Bravia TV. Enter now http://au.docs./homepageset/?p1=other & p2=au & p3=tagline > Hi Donna I'm not an expert on Ginkgo but it is something that I have taken myself for a while. I give my 40lb son 75mg ginkgo per day. 2000mg sounds alot but the labelling of ginkgo biloba seems to be much more confusing than it use to be. It might be worth checking the label to see if it says that the whole 2000mg are made up of active ingredients. When I first started taking Ginkgo for myself it used to state the concentration of the herb which was more important than the weight. Ginkgo is basically a blood thinner so I suppose in theory it could cause headaches and might not be very good for people whose blood does not clot very well. I believe that it is tissue building meaning that it could take a few weeks of dosing before there are any effects, I don't think that it is something that you ramp up, basically you stay at a maintenance dose. Some sources recommend a break from it now and then if taking long term and not to take too high a dose over a long period of time. I also believe that it is quite popular in Germany for Alzhiemers, strokes and for improved memory in the general population. I use it myself for tinnitus it helps a bit but to be honest nothing major. Kenny Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 5, 2008 Report Share Posted December 5, 2008 Yep, well I could only find the 2000mg tabs(equiv' to dry leaf 2g) standard' flavonglycosides 10.7mg, ginkgolides and bilobalide 2.7mg. Bit hard to get this down to 75mg. What I did today was give 1/8 tab (250mg) crushed and given 3 times during the day...sounds like he shouldn't even be getting this much though. Donna.  ________________________________ From: k.ozbo <k.ozbo@...> Sent: Friday, 5 December, 2008 5:22:01 PM Subject: [ ] Re: Ginkgo Biloba > > > Hi all, > I bought some Ginkgo Biloba today, 2000mg. > I had previously read that it increases blood flow to the brain?..I've no idea how much to give though, and how many times through day to give? > Ds is 17kg(37lbs). Is this one of those supps that needs to be increased to watch for side effects? > Donna. > > > Start your day with 7 and win a Sony Bravia TV. Enter now http://au.docs. / homepageset/ ?p1=other & p2=au & p3= tagline > Hi Donna I'm not an expert on Ginkgo but it is something that I have taken myself for a while. I give my 40lb son 75mg ginkgo per day. 2000mg sounds alot but the labelling of ginkgo biloba seems to be much more confusing than it use to be. It might be worth checking the label to see if it says that the whole 2000mg are made up of active ingredients. When I first started taking Ginkgo for myself it used to state the concentration of the herb which was more important than the weight. Ginkgo is basically a blood thinner so I suppose in theory it could cause headaches and might not be very good for people whose blood does not clot very well. I believe that it is tissue building meaning that it could take a few weeks of dosing before there are any effects, I don't think that it is something that you ramp up, basically you stay at a maintenance dose. Some sources recommend a break from it now and then if taking long term and not to take too high a dose over a long period of time. I also believe that it is quite popular in Germany for Alzhiemers, strokes and for improved memory in the general population. I use it myself for tinnitus it helps a bit but to be honest nothing major. Kenny Start your day with 7 and win a Sony Bravia TV. Enter now http://au.docs./homepageset/?p1=other & p2=au & p3=tagline Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 5, 2008 Report Share Posted December 5, 2008 > > > > > > Hi all, > > I bought some Ginkgo Biloba today, 2000mg. > > I had previously read that it increases blood flow to the > brain?..I've no idea how much to give though, and how many times > through day to give? > > Ds is 17kg(37lbs). Is this one of those supps that needs to be > increased to watch for side effects? > > Donna. > > > > > > Start your day with 7 and win a Sony Bravia TV. Enter > now http://au.docs. / homepageset/ ?p1=other & p2=au & p3= tagline > > > Hi Donna > I'm not an expert on Ginkgo but it is something that I have taken > myself for a while. > I give my 40lb son 75mg ginkgo per day. > 2000mg sounds alot but the labelling of ginkgo biloba seems to be > much more confusing than it use to be. It might be worth checking the > label to see if it says that the whole 2000mg are made up of active > ingredients. When I first started taking Ginkgo for myself it used to > state the concentration of the herb which was more important than the > weight. > Ginkgo is basically a blood thinner so I suppose in theory it could > cause headaches and might not be very good for people whose blood > does not clot very well. I believe that it is tissue building meaning > that it could take a few weeks of dosing before there are any effects, > I don't think that it is something that you ramp up, basically you > stay at a maintenance dose. Some sources recommend a break from it > now and then if taking long term and not to take too high a dose over > a long period of time. > I also believe that it is quite popular in Germany for Alzhiemers, > strokes and for improved memory in the general population. > I use it myself for tinnitus it helps a bit but to be honest nothing > major. > > Kenny > > > > > Start your day with 7 and win a Sony Bravia TV. Enter now http://au.docs./homepageset/?p1=other & p2=au & p3=tagline > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 6, 2008 Report Share Posted December 6, 2008 Well then, I 'should' be safe with using a full tablet, instead of an eighth, working up of course. Think this is one to ask my naturopath, to be on the safe side, seeing as I'm not getting much of a response elsewhere. Thanks,...Donna. ________________________________ From: k.ozbo <k.ozbo@...> Sent: Friday, 5 December, 2008 11:25:01 PM Subject: [ ] Re: Ginkgo Biloba > > > > > > Hi all, > > I bought some Ginkgo Biloba today, 2000mg. > > I had previously read that it increases blood flow to the > brain?..I've no idea how much to give though, and how many times > through day to give? > > Ds is 17kg(37lbs). Is this one of those supps that needs to be > increased to watch for side effects? > > Donna. > > > > > > Start your day with 7 and win a Sony Bravia TV. Enter > now http://au.docs. / homepageset/ ?p1=other & p2=au & p3= tagline > > > Hi Donna > I'm not an expert on Ginkgo but it is something that I have taken > myself for a while. > I give my 40lb son 75mg ginkgo per day. > 2000mg sounds alot but the labelling of ginkgo biloba seems to be > much more confusing than it use to be. It might be worth checking the > label to see if it says that the whole 2000mg are made up of active > ingredients. When I first started taking Ginkgo for myself it used to > state the concentration of the herb which was more important than the > weight. > Ginkgo is basically a blood thinner so I suppose in theory it could > cause headaches and might not be very good for people whose blood > does not clot very well. I believe that it is tissue building meaning > that it could take a few weeks of dosing before there are any effects, > I don't think that it is something that you ramp up, basically you > stay at a maintenance dose. Some sources recommend a break from it > now and then if taking long term and not to take too high a dose over > a long period of time. > I also believe that it is quite popular in Germany for Alzhiemers, > strokes and for improved memory in the general population. > I use it myself for tinnitus it helps a bit but to be honest nothing > major. > > Kenny > > > > > Start your day with 7 and win a Sony Bravia TV. Enter now http://au.docs. / homepageset/ ?p1=other & p2=au & p3= tagline > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 6, 2008 Report Share Posted December 6, 2008 This should spark some interest....... We've been giving Ginkgo biloba for a couple of years now. 75mg, three times a day. While I believe it has been beneficial, with many of these herbal remedies there is always the question of what constitutes a therapeutic dose and what is the best timing of the dose? For example, low dose biotin is excellent for long term anti yeast in the gut, however for people who have a biotin deficiency in the basal ganglia, then a short term high dose of biotin will give a result not seen with the low dose biotin. So basically I have a list of things we are doing and I am reviewing them one by one to see if there is better ways to administer some supplements for different therapeutic effect. I was due to review Ginkgo biloba over Christmas, but given all the questions I thought I might as well start the process earlier. So I would not say I have definite conclusions yet, however after plowing through hundreds of abstracts on ginkgo studies so far I have found some very interesting observations from both animal and human studies. As I look into it further there will be some studies where I will obviously need to read the complete study. So far I have not read any studies that find any serious toxic issues with high dose Ginkgo for the patient themselves, HOWEVER, from what I have read someone who is pregnant should NOT take HIGH DOSE ginkgo because of potential issues with bleeding and there have also been observable delays to growth of the fetus in animal studies. Though even here, there were an number of studies testing for bleeding issues and still found Ginkgo to be safe. But I still think better to be safe than sorry when it comes to pregnancy. The myriad of different problems where Ginkgo can help is quite astounding. The most common mechanism in which it does so seems to be its antioxidant properties. What was also interesting was of the few studies I found that basically tried to imply that Ginkgo does nothing at all (about 3% of what I have read), in each case the study happened to be published in a pharmacology journal, AND in each case the study didn't actually study anything itself (no patients or animals) but simply did a " review of the literature " to determine that Ginkgo was still useless. Very interesting pattern of behaviour. They must have found a whole heap of different studies that I did not come across through pubmed. People can draw their own conclusions. There were of course some studies that were direct studies and showed Ginkgo did not address particular problems. Obviously no herb can fix everything... but Gingko sure seems to do a lot. Many of the studies show improvements for conditions where there has been a restriction in blood supply (and hence oxygen) for numerous reasons. Interestingly one study found this was effective at a dose of 45mg per kg per day, BUT that the effectiveness disappeared at 90mg per kg per day. Other areas where Ginkgo was helpful and interesting observations included: -neuroprotection against free radical damage (free radical scavenging activity) -neuroprotection against excitotoxicity -protecting neurons from specific synapse damage -neuroprotective effect in the hippocampus region -inhibiting oxidative stress -protective effects against induced cell death -improved blood circulation -improved memory (even at low dose) -improved learning -improved attention (better with higher doses) -cardioprotective (protects cardiovascular tissue) -inhibition of lipid preoxidation (ie protecting cell membranes from damage) -reduce inflammation -reduced cognitive impairments (ie increase cognition for a patient with damage) -decreasing intracellular calcium concentration -regulation of hippocampal acetylcholine -increased nerve regeneration (the higher the dose the better the result, at doses up to 200mg per kg per day) -may increase intracellular cAMP and cGMP production -may work well in conjunction with phosphatidylserine -as an antioxidant protected against mercury induced oxidative damage of brain, lung, lover and kidney tissue -prevents homocysteine induced vascular injury -through antioxidant activity is beneficial to the immune system General half life was 1.5 hours. Peak concentrations tended to occur at about 10 minutes from entering the blood stream (so you need to factor in time for digestion). However this did not include in brain and fat. Tissue concentrations declined significantly by 6 hours (though was still present). One paper made the point that Ginkgo's therapeutic potential is limited by its instability. I have not read enough to give a thorough and confident assessment of appropriate dosages. So even though it would seem Ginkgo is generally safe, even at higher doses, most of the studies done that have used higher doses are talking about periods of a few weeks or less. I have not yet come across any study that looks at prolonged use of Ginkgo at high doses. If anything else comes to light I will let the group know. Donna Bowerman wrote: > > > Hi all, > I bought some Ginkgo Biloba today, 2000mg. > I had previously read that it increases blood flow to the brain?..I've > no idea how much to give though, and how many times through day to give? > Ds is 17kg(37lbs). Is this one of those supps that needs to be > increased to watch for side effects? > Donna. > > Start your day with 7 and win a Sony Bravia TV. Enter now > http://au.docs./homepageset/?p1=other & p2=au & p3=tagline > <http://au.docs./homepageset/?p1=other & p2=au & p3=tagline> > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 6, 2008 Report Share Posted December 6, 2008 , I appreciate that research and will be watching for more of your posts. I stopped giving ginkgo biloba a few months ago but before that, my children were taking it for about 8 months. It's really hard to know if something that affects brain function/blood flow/attention span is working, in my opinion. All I can really say is that, in general, my children have both improved in all areas from what we are doing. I can only pinpoint a few supplements that resulted in specific improvements. I did quite a bit of research on Amla, and I am sold that it is a great supplement for autism. I am giving it in my children's chelators as well as off-round. I have one study that says it is as effective as Nystatin in yeast fighting/control. > > > > > > Hi all, > > I bought some Ginkgo Biloba today, 2000mg. > > I had previously read that it increases blood flow to the brain?..I've > > no idea how much to give though, and how many times through day to give? > > Ds is 17kg(37lbs). Is this one of those supps that needs to be > > increased to watch for side effects? > > Donna. > > > > Start your day with 7 and win a Sony Bravia TV. Enter now > > http://au.docs./homepageset/?p1=other & p2=au & p3=tagline > > <http://au.docs./homepageset/?p1=other & p2=au & p3=tagline> > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 7, 2008 Report Share Posted December 7, 2008 , was does the label say on your Ginkgo-mg? Mine says 2000mg..have been giving 1/8tab didvided up 3 times/day http://www.chemistaustralia.com.au/products/natures-own-ginkgo-biloba-2000mg-50.\ html Donna. ________________________________ From: Reynolds <peter@...> Sent: Sunday, 7 December, 2008 12:24:03 AM Subject: Re: [ ] Ginkgo Biloba This should spark some interest.... ... We've been giving Ginkgo biloba for a couple of years now. 75mg, three times a day. While I believe it has been beneficial, with many of these herbal remedies there is always the question of what constitutes a therapeutic dose and what is the best timing of the dose? For example, low dose biotin is excellent for long term anti yeast in the gut, however for people who have a biotin deficiency in the basal ganglia, then a short term high dose of biotin will give a result not seen with the low dose biotin. So basically I have a list of things we are doing and I am reviewing them one by one to see if there is better ways to administer some supplements for different therapeutic effect. I was due to review Ginkgo biloba over Christmas, but given all the questions I thought I might as well start the process earlier. So I would not say I have definite conclusions yet, however after plowing through hundreds of abstracts on ginkgo studies so far I have found some very interesting observations from both animal and human studies. As I look into it further there will be some studies where I will obviously need to read the complete study. So far I have not read any studies that find any serious toxic issues with high dose Ginkgo for the patient themselves, HOWEVER, from what I have read someone who is pregnant should NOT take HIGH DOSE ginkgo because of potential issues with bleeding and there have also been observable delays to growth of the fetus in animal studies. Though even here, there were an number of studies testing for bleeding issues and still found Ginkgo to be safe. But I still think better to be safe than sorry when it comes to pregnancy. The myriad of different problems where Ginkgo can help is quite astounding. The most common mechanism in which it does so seems to be its antioxidant properties. What was also interesting was of the few studies I found that basically tried to imply that Ginkgo does nothing at all (about 3% of what I have read), in each case the study happened to be published in a pharmacology journal, AND in each case the study didn't actually study anything itself (no patients or animals) but simply did a " review of the literature " to determine that Ginkgo was still useless. Very interesting pattern of behaviour. They must have found a whole heap of different studies that I did not come across through pubmed. People can draw their own conclusions. There were of course some studies that were direct studies and showed Ginkgo did not address particular problems. Obviously no herb can fix everything.. . but Gingko sure seems to do a lot. Many of the studies show improvements for conditions where there has been a restriction in blood supply (and hence oxygen) for numerous reasons. Interestingly one study found this was effective at a dose of 45mg per kg per day, BUT that the effectiveness disappeared at 90mg per kg per day. Other areas where Ginkgo was helpful and interesting observations included: -neuroprotection against free radical damage (free radical scavenging activity) -neuroprotection against excitotoxicity -protecting neurons from specific synapse damage -neuroprotective effect in the hippocampus region -inhibiting oxidative stress -protective effects against induced cell death -improved blood circulation -improved memory (even at low dose) -improved learning -improved attention (better with higher doses) -cardioprotective (protects cardiovascular tissue) -inhibition of lipid preoxidation (ie protecting cell membranes from damage) -reduce inflammation -reduced cognitive impairments (ie increase cognition for a patient with damage) -decreasing intracellular calcium concentration -regulation of hippocampal acetylcholine -increased nerve regeneration (the higher the dose the better the result, at doses up to 200mg per kg per day) -may increase intracellular cAMP and cGMP production -may work well in conjunction with phosphatidylserine -as an antioxidant protected against mercury induced oxidative damage of brain, lung, lover and kidney tissue -prevents homocysteine induced vascular injury -through antioxidant activity is beneficial to the immune system General half life was 1.5 hours. Peak concentrations tended to occur at about 10 minutes from entering the blood stream (so you need to factor in time for digestion). However this did not include in brain and fat. Tissue concentrations declined significantly by 6 hours (though was still present). One paper made the point that Ginkgo's therapeutic potential is limited by its instability. I have not read enough to give a thorough and confident assessment of appropriate dosages. So even though it would seem Ginkgo is generally safe, even at higher doses, most of the studies done that have used higher doses are talking about periods of a few weeks or less. I have not yet come across any study that looks at prolonged use of Ginkgo at high doses. If anything else comes to light I will let the group know. Donna Bowerman wrote: > > > Hi all, > I bought some Ginkgo Biloba today, 2000mg. > I had previously read that it increases blood flow to the brain?..I've > no idea how much to give though, and how many times through day to give? > Ds is 17kg(37lbs). Is this one of those supps that needs to be > increased to watch for side effects? > Donna. > > Start your day with 7 and win a Sony Bravia TV. Enter now > http://au.docs. / homepageset/ ?p1=other & p2=au & p3= tagline > <http://au.docs. / homepageset/ ?p1=other & p2=au & p3= tagline> > > Quote Link to comment Share on other sites More sharing options...
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