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as I revisit caffeine connections - a couple links (below) that have

related info I found interesting. Histamine connections. I plan to

look into some of the ideas found in these. Adding in what I have

somewhat absorbed about possible toxic contributing factors made me go

" hmmm... " a few times, yk? Regardless, these helped to connect a few

dots, if nothing else, lolol...(btw, opinions welcome, if you actually

read these ;)

http://edmsllc.com/research_professional.htm

http://raypeat.com/articles/articles/caffeine.shtml

And questions - Can theophylline be metabolized to caffeine? Is this a

normal regular path for theophylline to take, or only under certain

circumstances??? Does anyone know more about this connection - I have

only come across one small blurb, with no references for the statement

- it is one of my " follow-up " things to check out. big sigh - make

that a blurb that I " noticed " this time around, at any rate ;) If

anyone here has a quick, or not so quick, answer, it would be much

appreciated.

wishing all the best

elizabeth

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The first link is over my head. I might try to slog through more of

it sometime though, because I do drink caffeine regularly and have for

years. My son would like me off of it. I do drink a lot less than I

used to. I don't have a specific goal to get off the caffeine but if

I figure out how to get well enough to not crave it regularly, I think

that would be a good thing.

I know for a fact that I drink more diet coke when I am exposed to

something I am allergic to. If I am really sucking down the sodas at

work, the odds are very good that when I go to the bathroom my face

will be all blotchy and red. I cannot tolerate coffee because it's so

acidifying. It tears up my stomach and gives me heartburn. (This is

undoubtedly related to my genetic disorder.)

Anyway, please share if you find anymore stuff on caffeine.

Michele

http://www.healthgazelle.org

http://www.kidslikemine.org

http://www.solanorail.org

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>

> The first link is over my head.

You know that Saturday Night Live skit where Farley and his

sports fan friends are in a bar talking, Jordan starts

talking and they all daze off and are thinking, " Da bears. bears.

Ditka. bears... " Anyway, that was exactly what I thought of when I

started reading the first link LOL :)

http://www.youtube.com/watch?v=JPP3aTB6nLo

I might try to slog through more of

> it sometime though, because I do drink caffeine regularly and have

for

> years. My son would like me off of it. I do drink a lot less than

I

> used to. I don't have a specific goal to get off the caffeine but

if

> I figure out how to get well enough to not crave it regularly, I

think

> that would be a good thing.

>

> I know for a fact that I drink more diet coke when I am exposed to

> something I am allergic to. If I am really sucking down the sodas

at

> work, the odds are very good that when I go to the bathroom my face

> will be all blotchy and red. I cannot tolerate coffee because it's

so

> acidifying. It tears up my stomach and gives me heartburn. (This

is

> undoubtedly related to my genetic disorder.)

>

> Anyway, please share if you find anymore stuff on caffeine.

>

> Michele

> http://www.healthgazelle.org

> http://www.kidslikemine.org

> http://www.solanorail.org

>

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thanks for the replies & the smiles :) The first link has enough

relatively familiar terms for me to try to muddle with it, but I do

struggle each time I read thru it. (yes, I really do read, reread,

reread & then rearead again, and again, and again ;) The one " real

life " thing I am trying, is adding sugar back to coffee & see if I

notice any difference. Twentyish yrs ago ;) I had switched from diet

coke to coffee, as a better (and cheaper :) thing to drink - I was

going thru about two cases a week, mostly at work, at that time. Then,

a couple years later, I switched from creamed/sugared coffee to black

coffee when trying to deal with arthritic issues, and sugar/salt were

recommended " get rid of's. " Since it was not a personal preference,

drinking coffee black, decided to see if makes a difference. and, I

would say that my " craving " for coffee goes down, only when I life &

supps & sleep & all that collide and I can feel that I am feeling

better, yk? For the most part, I don't try to curb my coffee ways,

tho I do experiment with alot of ideas - some with cause an increase &

some have turned out to be overall helpful...Most mainstream ideas

about coffee do not mesh with my own personal experience.

Another note - I did learn that the creamers are the worst, while

switching to black coffee. I tried drinking just coffee with creamer,

off & on - instant arthritic hand issues every time...

- chuckling, the " da bears... " analogy made me laugh - This is my

problem with the arginine/lysine/etc connections..every time I try to

work with the ideas, I come across waayyy too many unfamiliar terms &

everything that I " just " read, that I thought I was understanding,

turns into gobbledygook...and ends up being too much " wasted " energy

for that moment. erg.

wishing you the best, elizabeth

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requisite ps..thinking over the past ;) I inhaled coffee, at warp

speed - I will not ever admit to anyone, quite how much I was drinking

- I knew it was helping - at the very least, to it kept me moving when

nothing else would...while getting a lot of flak, that it was the

" underlying problem " ...this was the year directly following being

exposed to malathion - one of the key ideas, imo, is that this would

have been haphazardly stored & very casually used, which is not

cool...very much regarded as " safe " by my then dh...big sigh. I can

also note a definite pattern, as I am able to tag other definite

exposures - cleaning up insane amounts of (leftover) roach goo/powder,

a few years later, comes to mind..arg. Having a roller-coasterish type

of life, does mean it is somewhat easier to tag such fun things as

these. ig. wishing all the best, elizabeth

>

> thanks for the replies & the smiles :) The first link has enough

> relatively familiar terms for me to try to muddle with it, but I do

> struggle each time I read thru it. (yes, I really do read, reread,

> reread & then rearead again, and again, and again ;) The one " real

> life " thing I am trying, is adding sugar back to coffee & see if I

> notice any difference. Twentyish yrs ago ;) I had switched from diet

> coke to coffee, as a better (and cheaper :) thing to drink - I was

> going thru about two cases a week, mostly at work, at that time. Then,

> a couple years later, I switched from creamed/sugared coffee to black

> coffee when trying to deal with arthritic issues, and sugar/salt were

> recommended " get rid of's. " Since it was not a personal preference,

> drinking coffee black, decided to see if makes a difference. and, I

> would say that my " craving " for coffee goes down, only when I life &

> supps & sleep & all that collide and I can feel that I am feeling

> better, yk? For the most part, I don't try to curb my coffee ways,

> tho I do experiment with alot of ideas - some with cause an increase &

> some have turned out to be overall helpful...Most mainstream ideas

> about coffee do not mesh with my own personal experience.

> Another note - I did learn that the creamers are the worst, while

> switching to black coffee. I tried drinking just coffee with creamer,

> off & on - instant arthritic hand issues every time...

>

> - chuckling, the " da bears... " analogy made me laugh - This is my

> problem with the arginine/lysine/etc connections..every time I try to

> work with the ideas, I come across waayyy too many unfamiliar terms &

> everything that I " just " read, that I thought I was understanding,

> turns into gobbledygook...and ends up being too much " wasted " energy

> for that moment. erg.

>

> wishing you the best, elizabeth

>

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The coffee is restricting GABA utilisation in your brain. GABA is the

main inhibitory neurotransmitter in the brain.

Hence people get " fired up " on coffee.

eli8591 wrote:

>

> requisite ps..thinking over the past ;) I inhaled coffee, at warp

> speed - I will not ever admit to anyone, quite how much I was drinking

> - I knew it was helping - at the very least, to it kept me moving when

> nothing else would...while getting a lot of flak, that it was the

> " underlying problem " ...this was the year directly following being

> exposed to malathion - one of the key ideas, imo, is that this would

> have been haphazardly stored & very casually used, which is not

> cool...very much regarded as " safe " by my then dh...big sigh. I can

> also note a definite pattern, as I am able to tag other definite

> exposures - cleaning up insane amounts of (leftover) roach goo/powder,

> a few years later, comes to mind..arg. Having a roller-coasterish type

> of life, does mean it is somewhat easier to tag such fun things as

> these. ig. wishing all the best, elizabeth

>

>

> >

> > thanks for the replies & the smiles :) The first link has enough

> > relatively familiar terms for me to try to muddle with it, but I do

> > struggle each time I read thru it. (yes, I really do read, reread,

> > reread & then rearead again, and again, and again ;) The one " real

> > life " thing I am trying, is adding sugar back to coffee & see if I

> > notice any difference. Twentyish yrs ago ;) I had switched from diet

> > coke to coffee, as a better (and cheaper :) thing to drink - I was

> > going thru about two cases a week, mostly at work, at that time. Then,

> > a couple years later, I switched from creamed/sugared coffee to black

> > coffee when trying to deal with arthritic issues, and sugar/salt were

> > recommended " get rid of's. " Since it was not a personal preference,

> > drinking coffee black, decided to see if makes a difference. and, I

> > would say that my " craving " for coffee goes down, only when I life &

> > supps & sleep & all that collide and I can feel that I am feeling

> > better, yk? For the most part, I don't try to curb my coffee ways,

> > tho I do experiment with alot of ideas - some with cause an increase &

> > some have turned out to be overall helpful...Most mainstream ideas

> > about coffee do not mesh with my own personal experience.

> > Another note - I did learn that the creamers are the worst, while

> > switching to black coffee. I tried drinking just coffee with creamer,

> > off & on - instant arthritic hand issues every time...

> >

> > - chuckling, the " da bears... " analogy made me laugh - This is my

> > problem with the arginine/lysine/etc connections..every time I try to

> > work with the ideas, I come across waayyy too many unfamiliar terms &

> > everything that I " just " read, that I thought I was understanding,

> > turns into gobbledygook...and ends up being too much " wasted " energy

> > for that moment. erg.

> >

> > wishing you the best, elizabeth

> >

>

>

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I have had problems understanding gaba connections - can you

elaborate? Tho I understand the inhibiting neurotransmitters part well

enough ;) Am I right that coffee could be counteracting something

that is inhibiting " cells firing. " or is it a different thing? hmmm,

thinking receptor type issues might be a different thing vs. energy to

" fire. " make sense?

I will be looking into how this fits with what I think I understand so

far, thanks, wishing you the best, elizabeth

> > >

> > > thanks for the replies & the smiles :) The first link has enough

> > > relatively familiar terms for me to try to muddle with it, but I do

> > > struggle each time I read thru it. (yes, I really do read, reread,

> > > reread & then rearead again, and again, and again ;) The one " real

> > > life " thing I am trying, is adding sugar back to coffee & see if I

> > > notice any difference. Twentyish yrs ago ;) I had switched from diet

> > > coke to coffee, as a better (and cheaper :) thing to drink - I was

> > > going thru about two cases a week, mostly at work, at that time.

Then,

> > > a couple years later, I switched from creamed/sugared coffee to

black

> > > coffee when trying to deal with arthritic issues, and sugar/salt

were

> > > recommended " get rid of's. " Since it was not a personal preference,

> > > drinking coffee black, decided to see if makes a difference. and, I

> > > would say that my " craving " for coffee goes down, only when I life &

> > > supps & sleep & all that collide and I can feel that I am feeling

> > > better, yk? For the most part, I don't try to curb my coffee ways,

> > > tho I do experiment with alot of ideas - some with cause an

increase &

> > > some have turned out to be overall helpful...Most mainstream ideas

> > > about coffee do not mesh with my own personal experience.

> > > Another note - I did learn that the creamers are the worst, while

> > > switching to black coffee. I tried drinking just coffee with

creamer,

> > > off & on - instant arthritic hand issues every time...

> > >

> > > - chuckling, the " da bears... " analogy made me laugh - This is my

> > > problem with the arginine/lysine/etc connections..every time I

try to

> > > work with the ideas, I come across waayyy too many unfamiliar

terms &

> > > everything that I " just " read, that I thought I was understanding,

> > > turns into gobbledygook...and ends up being too much " wasted " energy

> > > for that moment. erg.

> > >

> > > wishing you the best, elizabeth

> > >

> >

> >

>

>

>

>

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(re question to ) Doing a search & did find your ginkgo post -

looks like that will help connect some dots ;) ...thanks, wishing you

the best, elizabeth

> > > >

> > > > thanks for the replies & the smiles :) The first link has enough

> > > > relatively familiar terms for me to try to muddle with it, but

I do

> > > > struggle each time I read thru it. (yes, I really do read, reread,

> > > > reread & then rearead again, and again, and again ;) The one " real

> > > > life " thing I am trying, is adding sugar back to coffee & see if I

> > > > notice any difference. Twentyish yrs ago ;) I had switched

from diet

> > > > coke to coffee, as a better (and cheaper :) thing to drink - I was

> > > > going thru about two cases a week, mostly at work, at that time.

> Then,

> > > > a couple years later, I switched from creamed/sugared coffee to

> black

> > > > coffee when trying to deal with arthritic issues, and sugar/salt

> were

> > > > recommended " get rid of's. " Since it was not a personal

preference,

> > > > drinking coffee black, decided to see if makes a difference.

and, I

> > > > would say that my " craving " for coffee goes down, only when I

life &

> > > > supps & sleep & all that collide and I can feel that I am feeling

> > > > better, yk? For the most part, I don't try to curb my coffee ways,

> > > > tho I do experiment with alot of ideas - some with cause an

> increase &

> > > > some have turned out to be overall helpful...Most mainstream ideas

> > > > about coffee do not mesh with my own personal experience.

> > > > Another note - I did learn that the creamers are the worst, while

> > > > switching to black coffee. I tried drinking just coffee with

> creamer,

> > > > off & on - instant arthritic hand issues every time...

> > > >

> > > > - chuckling, the " da bears... " analogy made me laugh - This is my

> > > > problem with the arginine/lysine/etc connections..every time I

> try to

> > > > work with the ideas, I come across waayyy too many unfamiliar

> terms &

> > > > everything that I " just " read, that I thought I was understanding,

> > > > turns into gobbledygook...and ends up being too much " wasted "

energy

> > > > for that moment. erg.

> > > >

> > > > wishing you the best, elizabeth

> > > >

> > >

> > >

> >

> >

> >

> >

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I don't have enough science background (except a few years of

physiology classes), to intelligently comment on these, but I do

understand the basics of nerve transmission and will share a thought

I had.

I will say, I know I'm not giving up my caffeine from coffee or tea,

anytime soon.

The first link I found particularly interesting. Maybe someone with

more chemistry/science knowledge can shed some light. This is what

got my attention: I believe histamine levels rise in an allergic

response (if not, I don't have a point). If histamine levels effect

the Na+ - K pump, which in turn effects transmission of nerve

impulses, wouldn't an allergic reaction effect sensation, and not

just in the brain? If my interpretation has any basis than it would

make sense to me why sensory issues in kids can improve with dietary

changes or removing other allergens, or even NAET. ??

>

> as I revisit caffeine connections - a couple links (below) that have

> related info I found interesting. Histamine connections. I plan to

> look into some of the ideas found in these. Adding in what I have

> somewhat absorbed about possible toxic contributing factors made me

go

> " hmmm... " a few times, yk? Regardless, these helped to connect a few

> dots, if nothing else, lolol...(btw, opinions welcome, if you

actually

> read these ;)

>

> http://edmsllc.com/research_professional.htm

>

> http://raypeat.com/articles/articles/caffeine.shtml

>

> And questions - Can theophylline be metabolized to caffeine? Is

this a

> normal regular path for theophylline to take, or only under certain

> circumstances??? Does anyone know more about this connection - I

have

> only come across one small blurb, with no references for the

statement

> - it is one of my " follow-up " things to check out. big sigh - make

> that a blurb that I " noticed " this time around, at any rate ;) If

> anyone here has a quick, or not so quick, answer, it would be much

> appreciated.

>

> wishing all the best

> elizabeth

>

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>

> The first link I found particularly interesting. Maybe someone with

> more chemistry/science knowledge can shed some light. This is what

> got my attention: I believe histamine levels rise in an allergic

> response (if not, I don't have a point). If histamine levels effect

> the Na+ - K pump, which in turn effects transmission of nerve

> impulses, wouldn't an allergic reaction effect sensation, and not

> just in the brain?

The Na pump is what is defective with my genetic disorder. I would

love to understand that piece of it better because it may be connected

to why I have so many allergies. I used to not be so severely

chemically sensitive. I have reason to believe that the nutrition and

lifestyle approach I have taken has helped improve the functioning of

the Na pump for me and my son with the same disorder.

One thing I have concluded is that bringing down the high acid levels

inside my cells has helped with that. I believe the mechanism for

this is that when the cell is screwed up enough, the high acid levels

(and being out of whack in other ways) " cook " the proteins so they

wind up as useless string instead of being folded into a useful tool

for the cell. Some proteins can be refolded correctly and become

useful if the cell atmosphere is corrected. Others cannot but

correcting the cell atmosphere means that when new proteins are

created they will be more likely to fold properly.

FWIW and all that.

Michele

http://www.healthgazelle.org

http://www.kidslikemine.org

http://www.solanorail.org

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OT but do you mind if I ask the name of the genetic disorder?

Just curious because I have one that involves defective sodium ion

channels too. Where as for me, the sodium/potassium ion channels of

the muscles don't function correctly, usually staying open to long and

allowing excessive potassium build up in the muscles and then causing

muscle disturbances.

> >

> > The first link I found particularly interesting. Maybe someone with

> > more chemistry/science knowledge can shed some light. This is what

> > got my attention: I believe histamine levels rise in an allergic

> > response (if not, I don't have a point). If histamine levels effect

> > the Na+ - K pump, which in turn effects transmission of nerve

> > impulses, wouldn't an allergic reaction effect sensation, and not

> > just in the brain?

>

>

> The Na pump is what is defective with my genetic disorder. I would

> love to understand that piece of it better because it may be connected

> to why I have so many allergies. I used to not be so severely

> chemically sensitive. I have reason to believe that the nutrition and

> lifestyle approach I have taken has helped improve the functioning of

> the Na pump for me and my son with the same disorder.

>

> One thing I have concluded is that bringing down the high acid levels

> inside my cells has helped with that. I believe the mechanism for

> this is that when the cell is screwed up enough, the high acid levels

> (and being out of whack in other ways) " cook " the proteins so they

> wind up as useless string instead of being folded into a useful tool

> for the cell. Some proteins can be refolded correctly and become

> useful if the cell atmosphere is corrected. Others cannot but

> correcting the cell atmosphere means that when new proteins are

> created they will be more likely to fold properly.

>

> FWIW and all that.

>

> Michele

> http://www.healthgazelle.org

> http://www.kidslikemine.org

> http://www.solanorail.org

>

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Hmmm.. this is interesting. About 15 yrs ago I was told I have a

disorder of muscle metabolism called myoadneylate deaminase deficency-

I think that's it. At the time I was in my early 20's suffering from

debilitating fatique, pain, muscle spasms, numbness. I was told it

was just a fluke thing, genetic, didn't really mean anything, learn

to manage. I changed diet and lifestyle and felt better, and haven't

even thought about it years. Now I wonder if this has something to do

with my son's issues.

-- In , " Michele " <talithamichele@...>

wrote:

>

>

> >

> > The first link I found particularly interesting. Maybe someone

with

> > more chemistry/science knowledge can shed some light. This is

what

> > got my attention: I believe histamine levels rise in an allergic

> > response (if not, I don't have a point). If histamine levels

effect

> > the Na+ - K pump, which in turn effects transmission of nerve

> > impulses, wouldn't an allergic reaction effect sensation, and not

> > just in the brain?

>

>

> The Na pump is what is defective with my genetic disorder. I would

> love to understand that piece of it better because it may be

connected

> to why I have so many allergies. I used to not be so severely

> chemically sensitive. I have reason to believe that the nutrition

and

> lifestyle approach I have taken has helped improve the functioning

of

> the Na pump for me and my son with the same disorder.

>

> One thing I have concluded is that bringing down the high acid

levels

> inside my cells has helped with that. I believe the mechanism for

> this is that when the cell is screwed up enough, the high acid

levels

> (and being out of whack in other ways) " cook " the proteins so they

> wind up as useless string instead of being folded into a useful tool

> for the cell. Some proteins can be refolded correctly and become

> useful if the cell atmosphere is corrected. Others cannot but

> correcting the cell atmosphere means that when new proteins are

> created they will be more likely to fold properly.

>

> FWIW and all that.

>

> Michele

> http://www.healthgazelle.org

> http://www.kidslikemine.org

> http://www.solanorail.org

>

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yes, that's different than what I have. Mine was verified with EMG

testing, and some of my relatives have it. Daughter does, but so far

we don't think my son does. Mine is a channelopathy. Yours a muscle

metabolism disorder. Mine gets severe if I eat potassium.

Did they verify with dna or some other test?

What I did learn was that mercury made mine worse than it should have

been. I had symptoms that were not supposed to be part of my disease.

Then I had fillings removed and many things improved. I now have the

least symptoms of my family...they still have their amalgams and

suffer a lot more than I do. But I did learn that I have to avoid

chemicals, junk foods, caffeine, etc. Definitely chemicals like sugar

substitutes because those affect the ion channels.

The doctor was dumbfounded when I reported what symptoms had gone away

and what I did to get rid of them. Even the neuropathy in my legs was

gone. I regained better muscle control of my hands and feet. They were

really amazed and then when I explained about mercury being a

neurotoxin, they said ironically I was not the first one to come into

the MDA clinic and say that I had taken out my fillings and was

improving. They had one guy cure himself of MS by removing his

fillings. Of course, they don't look any further into it.

I was also told no cure, deal with it.

It could affect him if it is genetic and he has it.

What makes this interesting is that according to what I am reading, if

my histamine levels were too high..my muscles would be hurting

worse....very interesting because my sister tested high on C reactive

for inflammation and she has way more symptoms and pain than I do. She

still has her amalgams, leaky gut and such.

Just a note that I got more chemically sensitive as I got older and it

got worse, then I had my amalgams removed and began liver

support/chelation. It has improved with that. It's not gone totally

yet, but a lot better than it used to be. I had read in Andy's book

that chemical sensitivity was due to liver issues.

> > >

> > > The first link I found particularly interesting. Maybe someone

> with

> > > more chemistry/science knowledge can shed some light. This is

> what

> > > got my attention: I believe histamine levels rise in an allergic

> > > response (if not, I don't have a point). If histamine levels

> effect

> > > the Na+ - K pump, which in turn effects transmission of nerve

> > > impulses, wouldn't an allergic reaction effect sensation, and not

> > > just in the brain?

> >

> >

> > The Na pump is what is defective with my genetic disorder. I would

> > love to understand that piece of it better because it may be

> connected

> > to why I have so many allergies. I used to not be so severely

> > chemically sensitive. I have reason to believe that the nutrition

> and

> > lifestyle approach I have taken has helped improve the functioning

> of

> > the Na pump for me and my son with the same disorder.

> >

> > One thing I have concluded is that bringing down the high acid

> levels

> > inside my cells has helped with that. I believe the mechanism for

> > this is that when the cell is screwed up enough, the high acid

> levels

> > (and being out of whack in other ways) " cook " the proteins so they

> > wind up as useless string instead of being folded into a useful tool

> > for the cell. Some proteins can be refolded correctly and become

> > useful if the cell atmosphere is corrected. Others cannot but

> > correcting the cell atmosphere means that when new proteins are

> > created they will be more likely to fold properly.

> >

> > FWIW and all that.

> >

> > Michele

> > http://www.healthgazelle.org

> > http://www.kidslikemine.org

> > http://www.solanorail.org

> >

>

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