Guest guest Posted December 11, 2008 Report Share Posted December 11, 2008 as I revisit caffeine connections - a couple links (below) that have related info I found interesting. Histamine connections. I plan to look into some of the ideas found in these. Adding in what I have somewhat absorbed about possible toxic contributing factors made me go " hmmm... " a few times, yk? Regardless, these helped to connect a few dots, if nothing else, lolol...(btw, opinions welcome, if you actually read these http://edmsllc.com/research_professional.htm http://raypeat.com/articles/articles/caffeine.shtml And questions - Can theophylline be metabolized to caffeine? Is this a normal regular path for theophylline to take, or only under certain circumstances??? Does anyone know more about this connection - I have only come across one small blurb, with no references for the statement - it is one of my " follow-up " things to check out. big sigh - make that a blurb that I " noticed " this time around, at any rate If anyone here has a quick, or not so quick, answer, it would be much appreciated. wishing all the best elizabeth Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 11, 2008 Report Share Posted December 11, 2008 The first link is over my head. I might try to slog through more of it sometime though, because I do drink caffeine regularly and have for years. My son would like me off of it. I do drink a lot less than I used to. I don't have a specific goal to get off the caffeine but if I figure out how to get well enough to not crave it regularly, I think that would be a good thing. I know for a fact that I drink more diet coke when I am exposed to something I am allergic to. If I am really sucking down the sodas at work, the odds are very good that when I go to the bathroom my face will be all blotchy and red. I cannot tolerate coffee because it's so acidifying. It tears up my stomach and gives me heartburn. (This is undoubtedly related to my genetic disorder.) Anyway, please share if you find anymore stuff on caffeine. Michele http://www.healthgazelle.org http://www.kidslikemine.org http://www.solanorail.org Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 11, 2008 Report Share Posted December 11, 2008 > > The first link is over my head. You know that Saturday Night Live skit where Farley and his sports fan friends are in a bar talking, Jordan starts talking and they all daze off and are thinking, " Da bears. bears. Ditka. bears... " Anyway, that was exactly what I thought of when I started reading the first link LOL http://www.youtube.com/watch?v=JPP3aTB6nLo I might try to slog through more of > it sometime though, because I do drink caffeine regularly and have for > years. My son would like me off of it. I do drink a lot less than I > used to. I don't have a specific goal to get off the caffeine but if > I figure out how to get well enough to not crave it regularly, I think > that would be a good thing. > > I know for a fact that I drink more diet coke when I am exposed to > something I am allergic to. If I am really sucking down the sodas at > work, the odds are very good that when I go to the bathroom my face > will be all blotchy and red. I cannot tolerate coffee because it's so > acidifying. It tears up my stomach and gives me heartburn. (This is > undoubtedly related to my genetic disorder.) > > Anyway, please share if you find anymore stuff on caffeine. > > Michele > http://www.healthgazelle.org > http://www.kidslikemine.org > http://www.solanorail.org > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 12, 2008 Report Share Posted December 12, 2008 thanks for the replies & the smiles The first link has enough relatively familiar terms for me to try to muddle with it, but I do struggle each time I read thru it. (yes, I really do read, reread, reread & then rearead again, and again, and again The one " real life " thing I am trying, is adding sugar back to coffee & see if I notice any difference. Twentyish yrs ago I had switched from diet coke to coffee, as a better (and cheaper thing to drink - I was going thru about two cases a week, mostly at work, at that time. Then, a couple years later, I switched from creamed/sugared coffee to black coffee when trying to deal with arthritic issues, and sugar/salt were recommended " get rid of's. " Since it was not a personal preference, drinking coffee black, decided to see if makes a difference. and, I would say that my " craving " for coffee goes down, only when I life & supps & sleep & all that collide and I can feel that I am feeling better, yk? For the most part, I don't try to curb my coffee ways, tho I do experiment with alot of ideas - some with cause an increase & some have turned out to be overall helpful...Most mainstream ideas about coffee do not mesh with my own personal experience. Another note - I did learn that the creamers are the worst, while switching to black coffee. I tried drinking just coffee with creamer, off & on - instant arthritic hand issues every time... - chuckling, the " da bears... " analogy made me laugh - This is my problem with the arginine/lysine/etc connections..every time I try to work with the ideas, I come across waayyy too many unfamiliar terms & everything that I " just " read, that I thought I was understanding, turns into gobbledygook...and ends up being too much " wasted " energy for that moment. erg. wishing you the best, elizabeth Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 12, 2008 Report Share Posted December 12, 2008 requisite ps..thinking over the past I inhaled coffee, at warp speed - I will not ever admit to anyone, quite how much I was drinking - I knew it was helping - at the very least, to it kept me moving when nothing else would...while getting a lot of flak, that it was the " underlying problem " ...this was the year directly following being exposed to malathion - one of the key ideas, imo, is that this would have been haphazardly stored & very casually used, which is not cool...very much regarded as " safe " by my then dh...big sigh. I can also note a definite pattern, as I am able to tag other definite exposures - cleaning up insane amounts of (leftover) roach goo/powder, a few years later, comes to mind..arg. Having a roller-coasterish type of life, does mean it is somewhat easier to tag such fun things as these. ig. wishing all the best, elizabeth > > thanks for the replies & the smiles The first link has enough > relatively familiar terms for me to try to muddle with it, but I do > struggle each time I read thru it. (yes, I really do read, reread, > reread & then rearead again, and again, and again The one " real > life " thing I am trying, is adding sugar back to coffee & see if I > notice any difference. Twentyish yrs ago I had switched from diet > coke to coffee, as a better (and cheaper thing to drink - I was > going thru about two cases a week, mostly at work, at that time. Then, > a couple years later, I switched from creamed/sugared coffee to black > coffee when trying to deal with arthritic issues, and sugar/salt were > recommended " get rid of's. " Since it was not a personal preference, > drinking coffee black, decided to see if makes a difference. and, I > would say that my " craving " for coffee goes down, only when I life & > supps & sleep & all that collide and I can feel that I am feeling > better, yk? For the most part, I don't try to curb my coffee ways, > tho I do experiment with alot of ideas - some with cause an increase & > some have turned out to be overall helpful...Most mainstream ideas > about coffee do not mesh with my own personal experience. > Another note - I did learn that the creamers are the worst, while > switching to black coffee. I tried drinking just coffee with creamer, > off & on - instant arthritic hand issues every time... > > - chuckling, the " da bears... " analogy made me laugh - This is my > problem with the arginine/lysine/etc connections..every time I try to > work with the ideas, I come across waayyy too many unfamiliar terms & > everything that I " just " read, that I thought I was understanding, > turns into gobbledygook...and ends up being too much " wasted " energy > for that moment. erg. > > wishing you the best, elizabeth > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 12, 2008 Report Share Posted December 12, 2008 The coffee is restricting GABA utilisation in your brain. GABA is the main inhibitory neurotransmitter in the brain. Hence people get " fired up " on coffee. eli8591 wrote: > > requisite ps..thinking over the past I inhaled coffee, at warp > speed - I will not ever admit to anyone, quite how much I was drinking > - I knew it was helping - at the very least, to it kept me moving when > nothing else would...while getting a lot of flak, that it was the > " underlying problem " ...this was the year directly following being > exposed to malathion - one of the key ideas, imo, is that this would > have been haphazardly stored & very casually used, which is not > cool...very much regarded as " safe " by my then dh...big sigh. I can > also note a definite pattern, as I am able to tag other definite > exposures - cleaning up insane amounts of (leftover) roach goo/powder, > a few years later, comes to mind..arg. Having a roller-coasterish type > of life, does mean it is somewhat easier to tag such fun things as > these. ig. wishing all the best, elizabeth > > > > > > thanks for the replies & the smiles The first link has enough > > relatively familiar terms for me to try to muddle with it, but I do > > struggle each time I read thru it. (yes, I really do read, reread, > > reread & then rearead again, and again, and again The one " real > > life " thing I am trying, is adding sugar back to coffee & see if I > > notice any difference. Twentyish yrs ago I had switched from diet > > coke to coffee, as a better (and cheaper thing to drink - I was > > going thru about two cases a week, mostly at work, at that time. Then, > > a couple years later, I switched from creamed/sugared coffee to black > > coffee when trying to deal with arthritic issues, and sugar/salt were > > recommended " get rid of's. " Since it was not a personal preference, > > drinking coffee black, decided to see if makes a difference. and, I > > would say that my " craving " for coffee goes down, only when I life & > > supps & sleep & all that collide and I can feel that I am feeling > > better, yk? For the most part, I don't try to curb my coffee ways, > > tho I do experiment with alot of ideas - some with cause an increase & > > some have turned out to be overall helpful...Most mainstream ideas > > about coffee do not mesh with my own personal experience. > > Another note - I did learn that the creamers are the worst, while > > switching to black coffee. I tried drinking just coffee with creamer, > > off & on - instant arthritic hand issues every time... > > > > - chuckling, the " da bears... " analogy made me laugh - This is my > > problem with the arginine/lysine/etc connections..every time I try to > > work with the ideas, I come across waayyy too many unfamiliar terms & > > everything that I " just " read, that I thought I was understanding, > > turns into gobbledygook...and ends up being too much " wasted " energy > > for that moment. erg. > > > > wishing you the best, elizabeth > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 12, 2008 Report Share Posted December 12, 2008 I have had problems understanding gaba connections - can you elaborate? Tho I understand the inhibiting neurotransmitters part well enough Am I right that coffee could be counteracting something that is inhibiting " cells firing. " or is it a different thing? hmmm, thinking receptor type issues might be a different thing vs. energy to " fire. " make sense? I will be looking into how this fits with what I think I understand so far, thanks, wishing you the best, elizabeth > > > > > > thanks for the replies & the smiles The first link has enough > > > relatively familiar terms for me to try to muddle with it, but I do > > > struggle each time I read thru it. (yes, I really do read, reread, > > > reread & then rearead again, and again, and again The one " real > > > life " thing I am trying, is adding sugar back to coffee & see if I > > > notice any difference. Twentyish yrs ago I had switched from diet > > > coke to coffee, as a better (and cheaper thing to drink - I was > > > going thru about two cases a week, mostly at work, at that time. Then, > > > a couple years later, I switched from creamed/sugared coffee to black > > > coffee when trying to deal with arthritic issues, and sugar/salt were > > > recommended " get rid of's. " Since it was not a personal preference, > > > drinking coffee black, decided to see if makes a difference. and, I > > > would say that my " craving " for coffee goes down, only when I life & > > > supps & sleep & all that collide and I can feel that I am feeling > > > better, yk? For the most part, I don't try to curb my coffee ways, > > > tho I do experiment with alot of ideas - some with cause an increase & > > > some have turned out to be overall helpful...Most mainstream ideas > > > about coffee do not mesh with my own personal experience. > > > Another note - I did learn that the creamers are the worst, while > > > switching to black coffee. I tried drinking just coffee with creamer, > > > off & on - instant arthritic hand issues every time... > > > > > > - chuckling, the " da bears... " analogy made me laugh - This is my > > > problem with the arginine/lysine/etc connections..every time I try to > > > work with the ideas, I come across waayyy too many unfamiliar terms & > > > everything that I " just " read, that I thought I was understanding, > > > turns into gobbledygook...and ends up being too much " wasted " energy > > > for that moment. erg. > > > > > > wishing you the best, elizabeth > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 12, 2008 Report Share Posted December 12, 2008 (re question to ) Doing a search & did find your ginkgo post - looks like that will help connect some dots ...thanks, wishing you the best, elizabeth > > > > > > > > thanks for the replies & the smiles The first link has enough > > > > relatively familiar terms for me to try to muddle with it, but I do > > > > struggle each time I read thru it. (yes, I really do read, reread, > > > > reread & then rearead again, and again, and again The one " real > > > > life " thing I am trying, is adding sugar back to coffee & see if I > > > > notice any difference. Twentyish yrs ago I had switched from diet > > > > coke to coffee, as a better (and cheaper thing to drink - I was > > > > going thru about two cases a week, mostly at work, at that time. > Then, > > > > a couple years later, I switched from creamed/sugared coffee to > black > > > > coffee when trying to deal with arthritic issues, and sugar/salt > were > > > > recommended " get rid of's. " Since it was not a personal preference, > > > > drinking coffee black, decided to see if makes a difference. and, I > > > > would say that my " craving " for coffee goes down, only when I life & > > > > supps & sleep & all that collide and I can feel that I am feeling > > > > better, yk? For the most part, I don't try to curb my coffee ways, > > > > tho I do experiment with alot of ideas - some with cause an > increase & > > > > some have turned out to be overall helpful...Most mainstream ideas > > > > about coffee do not mesh with my own personal experience. > > > > Another note - I did learn that the creamers are the worst, while > > > > switching to black coffee. I tried drinking just coffee with > creamer, > > > > off & on - instant arthritic hand issues every time... > > > > > > > > - chuckling, the " da bears... " analogy made me laugh - This is my > > > > problem with the arginine/lysine/etc connections..every time I > try to > > > > work with the ideas, I come across waayyy too many unfamiliar > terms & > > > > everything that I " just " read, that I thought I was understanding, > > > > turns into gobbledygook...and ends up being too much " wasted " energy > > > > for that moment. erg. > > > > > > > > wishing you the best, elizabeth > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 12, 2008 Report Share Posted December 12, 2008 I don't have enough science background (except a few years of physiology classes), to intelligently comment on these, but I do understand the basics of nerve transmission and will share a thought I had. I will say, I know I'm not giving up my caffeine from coffee or tea, anytime soon. The first link I found particularly interesting. Maybe someone with more chemistry/science knowledge can shed some light. This is what got my attention: I believe histamine levels rise in an allergic response (if not, I don't have a point). If histamine levels effect the Na+ - K pump, which in turn effects transmission of nerve impulses, wouldn't an allergic reaction effect sensation, and not just in the brain? If my interpretation has any basis than it would make sense to me why sensory issues in kids can improve with dietary changes or removing other allergens, or even NAET. ?? > > as I revisit caffeine connections - a couple links (below) that have > related info I found interesting. Histamine connections. I plan to > look into some of the ideas found in these. Adding in what I have > somewhat absorbed about possible toxic contributing factors made me go > " hmmm... " a few times, yk? Regardless, these helped to connect a few > dots, if nothing else, lolol...(btw, opinions welcome, if you actually > read these > > http://edmsllc.com/research_professional.htm > > http://raypeat.com/articles/articles/caffeine.shtml > > And questions - Can theophylline be metabolized to caffeine? Is this a > normal regular path for theophylline to take, or only under certain > circumstances??? Does anyone know more about this connection - I have > only come across one small blurb, with no references for the statement > - it is one of my " follow-up " things to check out. big sigh - make > that a blurb that I " noticed " this time around, at any rate If > anyone here has a quick, or not so quick, answer, it would be much > appreciated. > > wishing all the best > elizabeth > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 12, 2008 Report Share Posted December 12, 2008 > > The first link I found particularly interesting. Maybe someone with > more chemistry/science knowledge can shed some light. This is what > got my attention: I believe histamine levels rise in an allergic > response (if not, I don't have a point). If histamine levels effect > the Na+ - K pump, which in turn effects transmission of nerve > impulses, wouldn't an allergic reaction effect sensation, and not > just in the brain? The Na pump is what is defective with my genetic disorder. I would love to understand that piece of it better because it may be connected to why I have so many allergies. I used to not be so severely chemically sensitive. I have reason to believe that the nutrition and lifestyle approach I have taken has helped improve the functioning of the Na pump for me and my son with the same disorder. One thing I have concluded is that bringing down the high acid levels inside my cells has helped with that. I believe the mechanism for this is that when the cell is screwed up enough, the high acid levels (and being out of whack in other ways) " cook " the proteins so they wind up as useless string instead of being folded into a useful tool for the cell. Some proteins can be refolded correctly and become useful if the cell atmosphere is corrected. Others cannot but correcting the cell atmosphere means that when new proteins are created they will be more likely to fold properly. FWIW and all that. Michele http://www.healthgazelle.org http://www.kidslikemine.org http://www.solanorail.org Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 12, 2008 Report Share Posted December 12, 2008 OT but do you mind if I ask the name of the genetic disorder? Just curious because I have one that involves defective sodium ion channels too. Where as for me, the sodium/potassium ion channels of the muscles don't function correctly, usually staying open to long and allowing excessive potassium build up in the muscles and then causing muscle disturbances. > > > > The first link I found particularly interesting. Maybe someone with > > more chemistry/science knowledge can shed some light. This is what > > got my attention: I believe histamine levels rise in an allergic > > response (if not, I don't have a point). If histamine levels effect > > the Na+ - K pump, which in turn effects transmission of nerve > > impulses, wouldn't an allergic reaction effect sensation, and not > > just in the brain? > > > The Na pump is what is defective with my genetic disorder. I would > love to understand that piece of it better because it may be connected > to why I have so many allergies. I used to not be so severely > chemically sensitive. I have reason to believe that the nutrition and > lifestyle approach I have taken has helped improve the functioning of > the Na pump for me and my son with the same disorder. > > One thing I have concluded is that bringing down the high acid levels > inside my cells has helped with that. I believe the mechanism for > this is that when the cell is screwed up enough, the high acid levels > (and being out of whack in other ways) " cook " the proteins so they > wind up as useless string instead of being folded into a useful tool > for the cell. Some proteins can be refolded correctly and become > useful if the cell atmosphere is corrected. Others cannot but > correcting the cell atmosphere means that when new proteins are > created they will be more likely to fold properly. > > FWIW and all that. > > Michele > http://www.healthgazelle.org > http://www.kidslikemine.org > http://www.solanorail.org > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 12, 2008 Report Share Posted December 12, 2008 Hmmm.. this is interesting. About 15 yrs ago I was told I have a disorder of muscle metabolism called myoadneylate deaminase deficency- I think that's it. At the time I was in my early 20's suffering from debilitating fatique, pain, muscle spasms, numbness. I was told it was just a fluke thing, genetic, didn't really mean anything, learn to manage. I changed diet and lifestyle and felt better, and haven't even thought about it years. Now I wonder if this has something to do with my son's issues. -- In , " Michele " <talithamichele@...> wrote: > > > > > > The first link I found particularly interesting. Maybe someone with > > more chemistry/science knowledge can shed some light. This is what > > got my attention: I believe histamine levels rise in an allergic > > response (if not, I don't have a point). If histamine levels effect > > the Na+ - K pump, which in turn effects transmission of nerve > > impulses, wouldn't an allergic reaction effect sensation, and not > > just in the brain? > > > The Na pump is what is defective with my genetic disorder. I would > love to understand that piece of it better because it may be connected > to why I have so many allergies. I used to not be so severely > chemically sensitive. I have reason to believe that the nutrition and > lifestyle approach I have taken has helped improve the functioning of > the Na pump for me and my son with the same disorder. > > One thing I have concluded is that bringing down the high acid levels > inside my cells has helped with that. I believe the mechanism for > this is that when the cell is screwed up enough, the high acid levels > (and being out of whack in other ways) " cook " the proteins so they > wind up as useless string instead of being folded into a useful tool > for the cell. Some proteins can be refolded correctly and become > useful if the cell atmosphere is corrected. Others cannot but > correcting the cell atmosphere means that when new proteins are > created they will be more likely to fold properly. > > FWIW and all that. > > Michele > http://www.healthgazelle.org > http://www.kidslikemine.org > http://www.solanorail.org > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 12, 2008 Report Share Posted December 12, 2008 yes, that's different than what I have. Mine was verified with EMG testing, and some of my relatives have it. Daughter does, but so far we don't think my son does. Mine is a channelopathy. Yours a muscle metabolism disorder. Mine gets severe if I eat potassium. Did they verify with dna or some other test? What I did learn was that mercury made mine worse than it should have been. I had symptoms that were not supposed to be part of my disease. Then I had fillings removed and many things improved. I now have the least symptoms of my family...they still have their amalgams and suffer a lot more than I do. But I did learn that I have to avoid chemicals, junk foods, caffeine, etc. Definitely chemicals like sugar substitutes because those affect the ion channels. The doctor was dumbfounded when I reported what symptoms had gone away and what I did to get rid of them. Even the neuropathy in my legs was gone. I regained better muscle control of my hands and feet. They were really amazed and then when I explained about mercury being a neurotoxin, they said ironically I was not the first one to come into the MDA clinic and say that I had taken out my fillings and was improving. They had one guy cure himself of MS by removing his fillings. Of course, they don't look any further into it. I was also told no cure, deal with it. It could affect him if it is genetic and he has it. What makes this interesting is that according to what I am reading, if my histamine levels were too high..my muscles would be hurting worse....very interesting because my sister tested high on C reactive for inflammation and she has way more symptoms and pain than I do. She still has her amalgams, leaky gut and such. Just a note that I got more chemically sensitive as I got older and it got worse, then I had my amalgams removed and began liver support/chelation. It has improved with that. It's not gone totally yet, but a lot better than it used to be. I had read in Andy's book that chemical sensitivity was due to liver issues. > > > > > > The first link I found particularly interesting. Maybe someone > with > > > more chemistry/science knowledge can shed some light. This is > what > > > got my attention: I believe histamine levels rise in an allergic > > > response (if not, I don't have a point). If histamine levels > effect > > > the Na+ - K pump, which in turn effects transmission of nerve > > > impulses, wouldn't an allergic reaction effect sensation, and not > > > just in the brain? > > > > > > The Na pump is what is defective with my genetic disorder. I would > > love to understand that piece of it better because it may be > connected > > to why I have so many allergies. I used to not be so severely > > chemically sensitive. I have reason to believe that the nutrition > and > > lifestyle approach I have taken has helped improve the functioning > of > > the Na pump for me and my son with the same disorder. > > > > One thing I have concluded is that bringing down the high acid > levels > > inside my cells has helped with that. I believe the mechanism for > > this is that when the cell is screwed up enough, the high acid > levels > > (and being out of whack in other ways) " cook " the proteins so they > > wind up as useless string instead of being folded into a useful tool > > for the cell. Some proteins can be refolded correctly and become > > useful if the cell atmosphere is corrected. Others cannot but > > correcting the cell atmosphere means that when new proteins are > > created they will be more likely to fold properly. > > > > FWIW and all that. > > > > Michele > > http://www.healthgazelle.org > > http://www.kidslikemine.org > > http://www.solanorail.org > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 12, 2008 Report Share Posted December 12, 2008 > > OT but do you mind if I ask the name of the genetic disorder? It's no secret: I and my oldest son both have a form of Cystic Fibrosis. Michele http://www.healthgazelle.org http://www.kidslikemine.org http://www.solanorail.org Quote Link to comment Share on other sites More sharing options...
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