Guest guest Posted June 9, 2006 Report Share Posted June 9, 2006 Hello Everyone! As most of you know, I don't post often but I *do* frequently study/research thru the archives. I know I've been generously blessed that my " condition " is not as serious as many in this group; that's a given. Now I'd like to impose on your wisdom, advice and experiences. I was forced to return to my rheumatologis because the PA was attacking my hands and feet. It had been 2 years since I'd sought her advice but my PCP wasn't comfortable prescribing DMARDS. During that time, I've been taking Mobic, Elavil, Norco, Soma, Evoxac, Oramorph, etc. while trying other pain meds as well during that time. Rheumy was very concerned about the obvious swelling at the base of the pinky and thumb on the left hand while acknowledging similar but lesser involvement on the right hand. She wanted to inject cortisone into those joints on the left hand to which I replied, " Alright, you get ONE chance. " (I've had other, limited experience with a cortisone injection during Desert Storm with carpal tunnel syndrome in the left hand/wrist which didn't seem to help. Most recently, my PCP gave me an injection of depo medrol which didn't help much other than the generalized swelling, especially in my legs and feet.) Rheumy prescribed methotraxte 2.5 (taking 5 tablets once/week) and folic acid 1 mg taken every day --- and then handed me brochures on Enbrel and Humira to read and decide which one I wanted to try. 1. How do I compare these 2 powerful biologics against each other? 2. Shouldn't I give the methotrexate some time by itself before adding another new drug and how long is enough -- 1-2 months? 3. What can I expect from these medications besides the unpleasant side effects described in all the literature? 4. When I'm eligible for Medicare in Sept., what can I count on from them with such drugs? This list is truly appreciated for its treasure of information, advice and wisdom; it has been a huge help to me over the last 10 years and I know I can count on your help this time, too. Many thanks from Patty in a sweltering Pineywoods of East Texas (Editor's Note: I think it's impossible to compare the two since Humira works for some and not others and the same is true for Enbrel. Enbrel has been around longer but that doesn't mean better. Humira is injected less frequently than Enbrel. I don't think it matters which one you try because if it doesn't work, you'll probably try the other one. Studies have shown that Enbrel and Humira work better with MTX than any of the 3 works by itself. You may not experience ANY of the side effects shown in the literature - many of us don't and you might be shocked by how much better you could end up feeling. Kathy F) Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 11, 2006 Report Share Posted June 11, 2006 Thanks, Kathy F for your comments. It helps to know that others have reached the similar conclusion that my rheumy did when she said MTX works better with one of the other two. I'm leaning toward Enbrel simply because it has been around longer. Patty in the HOT Pineywoods of East Texas > (Editor's Note: I think it's impossible to compare the two since Humira works for some and not others and the same is true for Enbrel. Enbrel has been around longer but that doesn't mean better. Humira is injected less frequently than Enbrel. I don't think it matters which one you try because if it doesn't work, you'll probably try the other one. Studies have shown that Enbrel and Humira work better with MTX than any of the 3 works by itself. You may not experience ANY of the side effects shown in the literature - many of us don't and you might be shocked by how much better you could end up feeling. Kathy F) > Quote Link to comment Share on other sites More sharing options...
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