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What is the blue stuff you inject to put dogs to sleep? My vet used it on my

dog, dying of lung cancer at 15, and he said that I was to expect her to

sigh and then collapse as a dead weight in my arms, never heard the sigh but

she was gone quickly enough, I think she died of exhaustion before the juice

even went in myself.

Carpenter

Re: Re: Doxycycline

>Just thought you might be interested to know that as vets we have been

using

>Doxycycline as a drug for respiratory disease in small animals and pigeons

>for sometime under the guise of Ronaxin and ornicure.Might be worth a trip

>to the vets!Only trouble is that we probably get charged even more than the

>medics do for it!

>

>Simon

>P.S. It helps our patients fly faster! any takers?

> Re: Doxycycline

>

>

>>

>> Hi Tony,

>>

>> Exxon Mobil have never insisted that people take doxycycline as malarial

>> prophylaxis - howver it it a requirement for all working in EG to take

>some

>> form of malarial prophylaxis and many prefer doxycycline to mefloquine.

>> Malarone is quickly becoming the prophylactic of choice -don't have to

>take

>> it for a month when you get back etc. Due to its expense (and some GP's

>> haven't heard of it/non UK licensed as a prophylactic) it is still not

>> widely in use.

>>

>> Cheers,

>> Bill

>>

>>

>>

>> _________________________________________________________________________

>> Get Your Private, Free E-mail from MSN Hotmail at http://www.hotmail.com.

>>

>>

>>

>>

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The blue stuff was Pentobarbitone Sodium 20% for euthanasia. It is a

barbiturate with anaesthetic properties at the right dose.At this dose it

will cause euthanasia, passing through anaesthetic levels and beyond in a

few moments.A pleasant way to go if you have to......

The sigh is at the end of induction apnoea, common with all the barbiturate

anaesthetics.

The solution is normally clear but dyes are added to avoid accidental

injection/confusion

with bottles of other barbiturate anaesthetics.The one we use is yellow.

Human equivalents is Nembutal.Good for intractable insomnia........or talk

to a medic! ha ha

Kind regards

Simon

Re: Doxycycline

> >

> >

> >>

> >> Hi Tony,

> >>

> >> Exxon Mobil have never insisted that people take doxycycline as

malarial

> >> prophylaxis - howver it it a requirement for all working in EG to take

> >some

> >> form of malarial prophylaxis and many prefer doxycycline to mefloquine.

> >> Malarone is quickly becoming the prophylactic of choice -don't have to

> >take

> >> it for a month when you get back etc. Due to its expense (and some GP's

> >> haven't heard of it/non UK licensed as a prophylactic) it is still not

> >> widely in use.

> >>

> >> Cheers,

> >> Bill

> >>

> >>

> >>

> >>

_________________________________________________________________________

> >> Get Your Private, Free E-mail from MSN Hotmail at

http://www.hotmail.com.

> >>

> >>

> >>

> >>

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You don't mean that atovaquone and proguanil by any chance.......? I think

by GlaxoWellcome

Simon

Re: Re: Doxycycline

> Very interesting Simon - unfortunately doxycycline costs pennies, don't

> suppose you use Malarone??

>

> Bill

>

>

>

> >

> >Just thought you might be interested to know that as vets we have been

> >using

> >Doxycycline as a drug for respiratory disease in small animals and

pigeons

> >for sometime under the guise of Ronaxin and ornicure.Might be worth a

trip

> >to the vets!Only trouble is that we probably get charged even more than

the

> >medics do for it!

> >

> >Simon

>

>

> _________________________________________________________________________

> Get Your Private, Free E-mail from MSN Hotmail at http://www.hotmail.com.

>

>

>

>

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Much obliged for the information.

You may not want to answer this. As a vet what do you think about the

vaccination of livestock against Foot and Mouth, is there actually a risk to

people from this course of action? I was told that in S.America they just

let it run its course. What is the virus called and does it have any

implications for humans or other animals apart from sheep, cattle and deer

etc?

Carpenter

Re: Re: Doxycycline

>The blue stuff was Pentobarbitone Sodium 20% for euthanasia. It is a

>barbiturate with anaesthetic properties at the right dose.At this dose it

>will cause euthanasia, passing through anaesthetic levels and beyond in a

>few moments.A pleasant way to go if you have to......

>The sigh is at the end of induction apnoea, common with all the

barbiturate

>anaesthetics.

>

>The solution is normally clear but dyes are added to avoid accidental

>injection/confusion

>with bottles of other barbiturate anaesthetics.The one we use is yellow.

>

>Human equivalents is Nembutal.Good for intractable insomnia........or talk

>to a medic! ha ha

>

>Kind regards

>Simon

> Re: Doxycycline

>> >

>> >

>> >>

>> >> Hi Tony,

>> >>

>> >> Exxon Mobil have never insisted that people take doxycycline as

>malarial

>> >> prophylaxis - howver it it a requirement for all working in EG to take

>> >some

>> >> form of malarial prophylaxis and many prefer doxycycline to

mefloquine.

>> >> Malarone is quickly becoming the prophylactic of choice -don't have to

>> >take

>> >> it for a month when you get back etc. Due to its expense (and some

GP's

>> >> haven't heard of it/non UK licensed as a prophylactic) it is still

not

>> >> widely in use.

>> >>

>> >> Cheers,

>> >> Bill

>> >>

>> >>

>> >>

>> >>

>_________________________________________________________________________

>> >> Get Your Private, Free E-mail from MSN Hotmail at

>http://www.hotmail.com.

>> >>

>> >>

>> >>

>> >>

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Hi Bill,

Malarone seems to be taking off although our official company stance is

still with Larium. I'm sure you have had the same experince of actually

noticing when the persons Larium day is!!.

My boss in town started Malarone the other month, his first week and ended

up posative PF Malaria!!.

One tip is to make sure they take it the same time as it has been known to

be short acting on the system.

Cheers

Tony

Re: Re: Doxycycline

> Very interesting Simon - unfortunately doxycycline costs pennies, don't

> suppose you use Malarone??

>

> Bill

>

>

>

> >

> >Just thought you might be interested to know that as vets we have been

> >using

> >Doxycycline as a drug for respiratory disease in small animals and

pigeons

> >for sometime under the guise of Ronaxin and ornicure.Might be worth a

trip

> >to the vets!Only trouble is that we probably get charged even more than

the

> >medics do for it!

> >

> >Simon

>

>

> _________________________________________________________________________

> Get Your Private, Free E-mail from MSN Hotmail at http://www.hotmail.com.

>

>

>

>

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  • 3 weeks later...
  • 1 year later...

Doxycycline

> In a message dated 11/23/02 3:39:38 AM Eastern Standard Time,

> writes:

First thing I'm addressing is EBV and that's why I'm doing this BHT

experiment and at the same time I'm taking Chisolm TF which not only covers

BHT but also lyme if I have it and even the lyme coinfections except for

one I think which he'll add to the formula in the near future. Also, he's

going to add mycoplasmas into his next formula several months from now and

he's gonna throw nanobacteria in too just for the heck of it.

>

,

I've lost your chain of thought here. Are you saying that Chisolm is going

to add mycoplasmas to their TF formulations, or did I misread you? If so,

do you know any approximate time frame? I've recently tested positive for m.

fermentans, and exploring treatment options.

Donna in NC

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Yes, you have it right Donna. Chisolm is going to add mycoplasma to

a whole new formula and it should have the nanobacteria in it too.

This formula should be a formula on its own and will not be mixed in

to the current #2 they they put out now for CFS which includes lyme

and most of the lyme coinfections. I would not look forward to it

any earlier than spring. I will alert the group when it comes out

though. Chip said it would be done quicker but the lab they get the

pathogens from is so busy that they actually put them on hold--maybe

b/c of 911 perhaps that the lab is so busy as to not give them the

pathogens they desire in a timely manner. So time is the factor

right now but at least the plan is in effect.

>

> Doxycycline

>

>

> > In a message dated 11/23/02 3:39:38 AM Eastern Standard Time,

> > @y... writes:

> First thing I'm addressing is EBV and that's why I'm doing this BHT

> experiment and at the same time I'm taking Chisolm TF which not

only covers

> BHT but also lyme if I have it and even the lyme coinfections

except for

> one I think which he'll add to the formula in the near future.

Also, he's

> going to add mycoplasmas into his next formula several months from

now and

> he's gonna throw nanobacteria in too just for the heck of it.

> >

>

> ,

> I've lost your chain of thought here. Are you saying that Chisolm

is going

> to add mycoplasmas to their TF formulations, or did I misread you?

If so,

> do you know any approximate time frame? I've recently tested

positive for m.

> fermentans, and exploring treatment options.

> Donna in NC

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  • 2 years later...
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Common Drug Found To Reduce Cartilage Loss In Knee Osteoarthritis

http://medicine.indiana.edu/news_releases/archive_03/doxycycline_knee_osteo03.ht\

ml

A study led by Indiana University scientists found that a common antibiotic

appears to reduce cartilage loss and pain in women whose knees show early signs

of the crippling effects of osteoarthritis.

The results suggest that doxycycline, a prescription medicine used to treat

infections and acne, suppresses enzymes that damage cartilage and may protect

cartilage not yet affected by the degenerative disease, said the scientist who

led the study.

D. Brandt, a professor of medicine and of orthopedic surgery at the

Indiana University School of Medicine, said the study is the first to

convincingly demonstrate a pharmacological effect in slowing cartilage damage in

patients with osteoarthritis.

He said the findings do not necessarily mean doxycycline could be a treatment

for osteoarthritis, but instead suggest a relatively fast method for testing a

wide range of drugs on a condition common among older Americans, especially

women.

" Up until this point there has been a general inhibition of doing this type of

research, " Brandt said. " The question has been, 'Could it demonstrate a drug

effect in people in a study that didn't cost the moon and take 20 years to

show? " '

Brandt, who was the principal investigator for the National Institutes of

Health-funded study, hopes the findings encourage other scientists and the

pharmaceutical industry to develop a variety of agents that can be similarly

tested.

Osteoarthritis is the leading cause of disability among elderly Americans,

afflicting about 70 percent of people over the age of 60.

The study was conducted over a 30-month period at six sites across the nation on

overweight women ranging in age from 45 to 64 years.

Study participants had standard X-ray evidence of osteoarthritis in only one

knee at the start of the trial but were at very high risk for the development of

osteoarthritis in the good knee in the near future, Brandt said.

Half of the 431 participants were randomly assigned to receive a placebo, and

the other half received doxycycline. Both the placebo and the 100 milligrams of

the antibiotic were administered twice daily to each participant.

At the end of the 30 months, X-rays showed that the women who received

doxycycline had an average 33 percent less cartilage loss - about 0.15 of a

millimeter less - in their affected knee, compared with the group that received

the placebo.

There was also preliminary evidence that doxycycline had a beneficial effect on

the participants' unaffected knees.

In addition, Brandt said the results showed that women taking doxycycline were

less likely to report " clinically significant increases " in knee pain compared

with those in the placebo group. And participants with the most frequent

increases in joint pain exhibited the most rapid loss of cartilage, he said.

Brandt said further study is needed to determine whether cartilage loss causes

pain or whether other factors may be to blame.

He said the study's most important contribution was using fluoroscopy - a

technique for obtaining " live " X-ray images of a living patient - to place each

subject's knees in the same position for the series of X-rays that tracked

changes in knee cartilage.

The study's initial results were released in November at the annual scientific

meeting of the American College of Rheumatology.

Marc C. Hochberg, a professor of medicine at the University of land in

Baltimore who was not involved in the study, said the findings are compelling

and add to evidence that certain enzymes produced by the body destroy cartilage.

Similar results with doxycycline had already been shown in animal studies, and

the next step will be to replicate Brandt's findings, he said.

" It would be nice to see a second study to replicate the results before we go

out with this recommendation that our patients take doxycycline, " Hochberg said.

He said some researchers are already trying to chemically modify some

tetracyclines - a family of antibiotics of which doxycycline is a member - to

remove their antibacterial qualities but preserve their ability to suppress the

damaging enzymes.

The goal would be a drug that provides a therapy for osteoarthritis without the

common side effects of antibiotics, including nausea, vomiting and light

sensitivity.

--------------------------------------------------------------------------------\

--------------------

INDIANAPOLIS - A common antibiotic may help control the pain and joint damage of

knee osteoarthritis, according to a recent study led by researchers at the

Indiana University School of Medicine.

Researchers at six sites studied the effect of doxycycline over a 30-month

period on women with knee osteoarthritis. Doxycycline is a member of the

tetracycline family of antibiotics.

D. Brandt, M.D., professor of medicine and of orthopaedic surgery and

director of the Section of Multipurpose Arthritis and Musculoskeletal Diseases

Center at the IU School of Medicine, was the principal investigator for this

National Institutes of Health study.

" This study is particularly noteworthy because it is the first one to

convincingly demonstrate a pharmacologic effect in slowing cartilage damage in

patients with osteoarthritis, " says Dr. Brandt.

The study looked at the progression of osteoarthritic cartilage loss and knee

pain in 431 women between the ages of 45 and 64 years, all of whom were

overweight. Study participants had standard X-ray evidence of osteoarthritis in

only one knee at the beginning of the trial.

Participants were randomly assigned to receive either doxycycline in the amount

of 100 milligrams twice daily or a placebo.

Doxycycline treatment resulted in a 33 percent decrease in the rate of cartilage

loss as shown in the X-rays. Although, doxycycline slowed the progression of

cartilage damage in the arthritic knee, it did not significantly affect the knee

that was not arthritic at the outset of the trial.

That is not surprising, Dr. Brandt says, because the underlying mechanisms of

joint damage respond differently to treatment at different stages of the

disease. He added that the positive effects seen with doxycycline did not

suggest that osteoarthritis was an infectious disease. This drug has a unique

quality among antibiotics that inhibits the enzymes responsible for the

softening and breakdown of joint cartilage in this form of arthritis, he said.

In general, reports of pain at the onset of the study were relatively low. As

the study progressed, participants taking doxycycline were less likely to report

clinically significant increases in knee pain in comparison to the group taking

placebo.

There was a direct correlation between frequency of flares of joint pain and the

rate of cartilage loss in the arthritic knee. Those with the most frequent

increases in joint pain exhibited the most rapid loss of cartilage.

" This raises the question of which is the chicken and which is the egg, " says

Dr. Brandt. " It has not been clear if the loss of cartilage results in joint

pain or whether other mechanisms that cause pain, and perhaps joint

inflammation, result in cartilage loss. This question warrants additional

study. "

The initial results of the study were released in November at the annual

scientific meeting of the American College of Rheumatology. Additional

information on the results of the study will be published in the near future.

IU School of Medicine staff involved with the study include A. Mazzuca,

Ph.D., professor and senior scientists in the Division of Rheumatology; Barry

Katz, director of the Division of Biostatistics in the IU Department of

Medicine, and Kathy Lane, study administrator.

Other participating sites were the University of Alabama at Birmingham,

Rush-Presbyterian-St. Lukes Medical Center, Northwestern University Medical

Center, University of Pittsburgh Medical Center and the Arthritis Research

Center Foundation in Wichita, Kan.

doxycycline

I READ SOMETHING ABOUT DOXY SLOWING THE

RATE OF CARTLIAGE LOSS, ANY INFO ON THIS?

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  • 2 years later...

Hi

last spring i did Doxycyclene for about 2 weeks for

the same thing--possibilty of lyme.

I felt like the bastards were really leaving me.

trying to exit from inside me.

but it made me so sensitive to the sun that i quit

taking it--i was getting fried with blisters.

i still think about taking it--it was the only time i

felt like they were really trying tto leave.

Rmember to take a good probiotic--the antibiotics will

give you candida.

love L

--- fritolay66 <fritolay66@...> wrote:

>

> I have been thinking again......eishhh Nasal

> Membranes.

>

> OK, it would seem when it was considered that I may

> have Lyme, I was put

> on doxy. During that time is when I became very

> ill. High fever,

> chills, body and joint ACHES, downright pain, and a

> headache from the

> black depths, nausea, vomiting, etc. But also

> during that time I

> noticed a change in my mites. I told you all they

> were falling off of

> me, and that I wasn't sure what was going on. At

> the time I didn't

> associate the doxy with the mites. Until yesterday.

> My forehead lesion

> hurt so bad and it was cherry red. Assuming cherry

> red indicated

> infection and the pain also, I took one of my doxy

> capsules and broke it

> apart just like you would with our MSM capsules. I

> dabbed the powder on

> the lesion and then rubbed it in with the MSM

> lotion. I had big ones

> (whatever that means, mites, follicle, I don't know

> things) popping out

> after application. I again tried it on my forehead

> this evening and

> wow. All day today I had black specks dropping out.

> I think I was in

> the bathroom half the day. Tonight I put it on a

> lesion on my arm.

> Same thing. I haven't been able to research the

> possibilities of doxy,

> but I was desperate for something for my nose. I

> didn't want to use

> lotion in my nose and I forgot about the olive oil

> thing, so I wet the

> tip of my finger, dabbed it in the doxy and swiped

> my nose. (Try not to

> visualize this, it isn't very flattering or lady

> like.....ROFL...jammed

> way up there I did....lol) I am still tasting doxy.

> But......it isn't

> poisoness, and it stopped activity in its tracks.

> Seems to dry them up

> and paralyze them. Now, don't all of you go and

> stick your fingers up

> your nose quite yet, I am not sure about this. Will

> observe for a

> couple of days and let you know. Hope you

> smiled......;)

>

>

>

>

>

>

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  • 3 years later...
Guest guest

Years ago, my first rheumy tried a month long course of a couple of

different antibiotics with topicals before we even tried light therapy for

my P. Felt as though it was the least invasive thing to rule out first. I

didn't come down with PA until after Katrina (and we know that wasn't

stressful to residents of New Orleans) and my dermatologist put me on

biologics as soon as he realized what was going on.

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Sometimes, when I get another illness like a cold or flu, I go off my PA meds so

that I can fight the infection with my body. Once the infection has left, I

often have a week or two when the PA symptoms nearly disappear. This has

recently happened to me again, and as i have stopped working, and my stress is

minimal, I find that I am feeling nearly the same without meds and no work as I

did with meds and work. In some ways, I feel better as I am not dealing with the

side effects of the meds. That's how it works for me, et. al. All the best

to everyone.

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Hi, I too stopped almost all of my meds (PsA & others). I've been off the Enbrel

for a month and off the Z-PAK for 2 weeks, I am in alot of pain in most of my

joints. I would really like to try some kind of natural pain relief but I don't

no what. Anyone recommend something cheap & effective.

Lori in AZ

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