Guest guest Posted April 17, 2010 Report Share Posted April 17, 2010 The reason you skip the folic acid on the day you take the MTX. The MTX is a folic acid depeleter, that is why it helps autoimmune diseases. You don't want to take the folic acid on the day you take the MTX as you are basically " inactivating " part of the MTX. Hope this helps. Rae Quote Link to comment Share on other sites More sharing options...
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