Re: What is going on with my body?

[Guest guest]

I am lost as to what your talking about because you started a new thread and

anything you posted before this thread is not there so tell me. Are you on TRT

doing 100 mgs per week and them labs are on TRT.

You need to understand now Testosterone works in the body Total T is all the

Testosterone your body's makes Free and % of Free Testosterone every Bio. T are

a small % of your Total Free T is only 2% of your Total T so as your Total T

gets to the upper 1/3 of your labs range then you test your free's becuse the 2%

of your higher Total will be a lot more Free T.

Also if your Estradiol levels are high your SHBG will be high and this will bind

up your Free T levels read this link.

Here is a cut and paste from it.

http://tinyurl.com/yhn3gnm

====================================================

When Testosterone is converted from cholesterol in the leydig cells of the

testis, it's released into the blood stream where it embarks on an anabolic

adventure.

However, when in the blood, 60% of the big T released from the boys down below

is bound up by a protein known as SHBG, or sex-hormone binding globulin. SHBG is

produced and released by the liver. The important point is that the Testosterone

bound to SHBG is biologically inactive and this is why there's an important

distinction between total T and bioavailable T.

Total T represents all the Testosterone in the blood, while bioavailable T

represents the non SHBG bound Testosterone. There are other proteins in the

blood that bind Testosterone, too, but their binding is rather weak, so this T

is bioavailable and these proteins can still enter the cells to produce and

effect all the things we're interested in.

As I said, bioavailable T represents the Testosterone that is not SHBG bound,

while free T represents the Testosterone that's not bound to any blood proteins

at all. It's tricky, I know, but I hope that it's now evident that although only

about 2% of the T in blood is technically considered free T, there is a larger

percentage of T (about 40% or so) that is bioavailable because it's only weakly

bound to non SHBG blood proteins.

I'm taking you through this complex path for good reason. When trying to

increase T levels in the body, one must attempt to not only increase total T.

More importantly, one must attempt to increase bioavailable T. If you increase

total T, but you increase SHBG to a larger extent, they you will actually have

less bioavailable T for muscle building purposes!

Co-Moderator

Phil

> From: csgelber@... <csgelber@...>

> Subject: What is going on with my body?

>

> Date: Friday, February 5, 2010, 1:07 PM

> How can testosterone be  552 ,

> with free testosterone on the low side? My scores  over

> the last few months have been:

>

> September 30, 2009 testosterone, total 552. Testosterone

> free/testosterone 1.46 standard range 1.5-2.20

>

> November 18, 2009 testosterone, total 349. Testosterone

> free/testosterone 1.31    standard range

> 1.5-2.20    FSH 5.63, and LH 2.14.

>

> January 15, 2010 testosterone, total 387. Testosterone

> free/testosterone 1.73     standard range

> 1.5-2.20

> FSH 7.68 and LH 3.79

>

> Additional information-I am a 42 year old male. I have had

> a varicocele for about 10 years. I'm going to mention this

> to a urologist. I also have osteoperosis. I have not had

> prolactin or estridol checked yet.

>

> Any guess as to what might be going on with my body by

> these numbers? A small 100 mg dose of testosterone helped me

> feel much much better. Would this confirm that I am

> hypeogonadal?

>

>

>

>

> ------------------------------------

>

>

[Guest guest]

Hi Phil,

Sorry for any confussion. I am on TRT 100MG every two weeks. My T has not been

checked since I started TRT (have only had one injection so far). So, is it

then possible to be hypogondal becuase of low free T?. I am wondering if this

can be the case with me when my T was 552, but my free T was 1.46 standard range

1.5-2.20.

Appreciate any insight you can shed into what you think might be the case with

what is going on in my body.

Curtis

>

> > From: csgelber@... <csgelber@...>

> > Subject: What is going on with my body?

> >

> > Date: Friday, February 5, 2010, 1:07 PM

> > How can testosterone be  552 ,

> > with free testosterone on the low side? My scores  over

> > the last few months have been:

> >

> > September 30, 2009 testosterone, total 552. Testosterone

> > free/testosterone 1.46 standard range 1.5-2.20

> >

> > November 18, 2009 testosterone, total 349. Testosterone

> > free/testosterone 1.31    standard range

> > 1.5-2.20    FSH 5.63, and LH 2.14.

> >

> > January 15, 2010 testosterone, total 387. Testosterone

> > free/testosterone 1.73     standard range

> > 1.5-2.20

> > FSH 7.68 and LH 3.79

> >

> > Additional information-I am a 42 year old male. I have had

> > a varicocele for about 10 years. I'm going to mention this

> > to a urologist. I also have osteoperosis. I have not had

> > prolactin or estridol checked yet.

> >

> > Any guess as to what might be going on with my body by

> > these numbers? A small 100 mg dose of testosterone helped me

> > feel much much better. Would this confirm that I am

> > hypeogonadal?

> >

> >

> >

> >

> > ------------------------------------

> >

> >

[Guest guest]

If I were you I would not do anymore shots and have your Estradiol levels

checked if they are high this can lower your Testosterone levels. Estradiol E2

in men is made from Testosterone so as your E2 levels go up your brain will

think it's Testosterone and slow down sending the LH and FSH message to your

testis and you end up with a lower level and E2 at high levels will up your SHBG

levels this will bind up any of your Free Testosterone. So test this if it's

high get on Indoplex/DIM or Arimidex to get your levels back down this will

lower your SHBG and unbind your Free T levels and your Total T can go up some

200 to 300 points and you don't need to be on shots. This low shot is not going

to do much anyway men start on 100 mgs every week not every 2 weeks.

http://www.medibolics.com/ArimidexBoostsTestosterone.htm

In this link it's about older men but I have seen this happen to younger men.

http://jcem.endojournals.org/cgi/content/full/89/3/1174

http://www.lef.org/magazine/mag2008/nov2008_Dangers-of-Excess-Estrogen-in-the-Ag\

ing-Male_01.htm

In this link it tells you everything you need to know about low T and high

Estradiol.

http://www.griffinmedical.com/male_hormone_modulation_therapy.html

Any men with levels in the 500's for Total Testosterone should have there

Estradiol checked first before going on TRT.

Co-Moderator

Phil

> From: csgelber@... <csgelber@...>

> Subject: Re: What is going on with my body?

>

> Date: Friday, February 5, 2010, 3:37 PM

>

>

> Hi Phil,

>

> Sorry for any confussion.  I am on TRT 100MG every two

> weeks.  My T has not been checked since I started TRT

> (have only had one injection so far).  So, is it then

> possible to be hypogondal becuase of low free T?.  I am

> wondering if this can be the case with me when my T was 552,

> but my free T was 1.46 standard range 1.5-2.20. 

>

> Appreciate any insight you can shed into what you think

> might be the case with what is going on in my body.

>

>

> Curtis

>

>

>

> >

> > > From: csgelber@... <csgelber@...>

> > > Subject: What is going on with my

> body?

> > >

> > > Date: Friday, February 5, 2010, 1:07 PM

> > > How can testosterone be  552 ,

> > > with free testosterone on the low side? My

> scores  over

> > > the last few months have been:

> > >

> > > September 30, 2009 testosterone, total 552.

> Testosterone

> > > free/testosterone 1.46 standard range 1.5-2.20

> > >

> > > November 18, 2009 testosterone, total 349.

> Testosterone

> > > free/testosterone 1.31    standard range

> > > 1.5-2.20    FSH 5.63, and LH 2.14.

> > >

> > > January 15, 2010 testosterone, total 387.

> Testosterone

> > > free/testosterone 1.73     standard range

> > > 1.5-2.20

> > > FSH 7.68 and LH 3.79

> > >

> > > Additional information-I am a 42 year old male. I

> have had

> > > a varicocele for about 10 years. I'm going to

> mention this

> > > to a urologist. I also have osteoperosis. I have

> not had

> > > prolactin or estridol checked yet.

> > >

> > > Any guess as to what might be going on with my

> body by

> > > these numbers? A small 100 mg dose of

> testosterone helped me

> > > feel much much better. Would this confirm that I

> am

> > > hypeogonadal?

> > >

> > >

> > >

> > >

> > > ------------------------------------

> > >

> > >

[Guest guest]

Phil, thanks for all the useful information. I am going to read up on the

links. The site has been very helpful!

> > >

> > > > From: csgelber@ <csgelber@>

> > > > Subject: What is going on with my

> > body?

> > > >

> > > > Date: Friday, February 5, 2010, 1:07 PM

> > > > How can testosterone be  552 ,

> > > > with free testosterone on the low side? My

> > scores  over

> > > > the last few months have been:

> > > >

> > > > September 30, 2009 testosterone, total 552.

> > Testosterone

> > > > free/testosterone 1.46 standard range 1.5-2.20

> > > >

> > > > November 18, 2009 testosterone, total 349.

> > Testosterone

> > > > free/testosterone 1.31    standard range

> > > > 1.5-2.20    FSH 5.63, and LH 2.14.

> > > >

> > > > January 15, 2010 testosterone, total 387.

> > Testosterone

> > > > free/testosterone 1.73     standard range

> > > > 1.5-2.20

> > > > FSH 7.68 and LH 3.79

> > > >

> > > > Additional information-I am a 42 year old male. I

> > have had

> > > > a varicocele for about 10 years. I'm going to

> > mention this

> > > > to a urologist. I also have osteoperosis. I have

> > not had

> > > > prolactin or estridol checked yet.

> > > >

> > > > Any guess as to what might be going on with my

> > body by

> > > > these numbers? A small 100 mg dose of

> > testosterone helped me

> > > > feel much much better. Would this confirm that I

> > am

> > > > hypeogonadal?

> > > >

> > > >

> > > >

> > > >

> > > > ------------------------------------

> > > >

> > > >

[Guest guest]

> Sorry for any confussion. I am on TRT 100MG every two weeks. My T has not

been checked since I started TRT (have only had one injection so far).

Hi,

at 100mg every 2 weeks after a month you'll be as low or lower than you were at

the beginning (assuming testing 2 weeks after shot).

after a month your testes will be shut down so it's ALL coming from the shot.

read up on the Dr. Crisler stuff in the files sections.

most common dose seems to be 100mg every week, with a few a little lower, and a

few a LOT higher (some folks are 150+mg/week) plus arimidex (which will keep

testosterone as testosterone instead of converting to estrogens) and many doing

HCG at 250iu twice a week (either days 5-6 just before the weekly shot, or the

day before on the twice a week bunch).

2+ week shots are so old school... but then you're new to this... maybe the doc

doesn't think you can administer your own shots? most here do... with a 25g or

even 27g (smaller than the doc uses) into the thigh... easy... first one is

hardest psychologically but after that it's a piece of cake.