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Need advice - pssd, hypogonadism, gynecomastia

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Hi everyone,

29 y old, PSSD sufferer after 7 years on Zoloft as a help to chronical fatigue

syndrome. During Zoloft I got lower libido, low sensation/pleasure from sexual

act, but not serious sexual problems. After quitting Zoloft, sensation came

back, libido a little better, but I became almost complete impotent. At the

moment 6 months SSRI free. Able to have sex only with Viagra and even that didnt

guarantee long effect. 2 months ago started to take Tyrosine and 5-HTP (this

boosts Serotonine as Zoloft does, but in different mechanisms). After a week

started to take 5-HTP before bedtime on empty stomach and next morning I got my

first morning wood (not after viagra nights) strong as in high schol. Next weeks

I saw much improvement in erections, in mornings at leat half-erections,

sometimes able to have sex without viagra, and even with viagra results were

much better than before. No side effects of lower pleasuer. After a month first

signs of Gynecomastia appeared, I misjudged them as aquiring fat. After second

month I noticed what Gyno is, dropped all drugs - it was a week ago. No

improvement since than. My gino is at least average, ashamed to wear shirts,

left breast is bigger than right and hurts.

What's interesting..

I made two hormonal tests in two different labs, both in the mornings on empty

stomach.

First, one week ago, day after dropping 5-HTP and Tyrosine

Estradiol 20 pg/ml normal value: max 56,00

Prolactine 9,2 ng/ml normal value: 2,5-17,00

Testosteron 648 ng/dl normal value: 262,00-1593,00

Testosteron free (this result got today, as they made the send it to lab in

other city /the same company/ ) 17,32 pg/ml normal value 4,0-42

Two days ago, five days after dropping got such results

LH 2,4 mlU/ml reference value 2,0-12,0

FSH 4,27 mlU/ml reference value 1,0-8,0

Testosterone 2,73 ng/ml reference value 1,95-11,38

Progesterone 0,59 ng/ml reference value <3,37

(reference value is where 95% in this lab are between, so 2,5% are lower than

minimal)

On monday I will get another tests, this time full 6-7 hormons at once and in

the monday evening i'm going to endocrynologist.

is this possible to get 2 such different results in 5 days span (more that 2

times lower test) - first results are almost perfect, second shows hypogonadism?

My hypothesis after analysing this result, is that after long period of Zoloft

in some hard to explain way, I need extra serotonine for pituary gland to have

any production of hormons. 5-htp mimicked this effect and boosted indirectly

testosteron, which normally is not the case. Without extra serotoine, I have

levels and symptoms of hypogonadism.

from my experience I do not expect a lot from my endo on monday, as docs do not

do well with such specifis cases. What should i try to convince him to do, as I

suppose he will advise waiting for gyno to disappear naturally.

Try Tamoxifen or Clomid? May it make gyno smaller or gives guarantee of no

further damage? Month after first sings, 10 days ago it got to current level.

Boost testosterone - androgel, injections or hCG ? Surely will help with

erection but gyno will be worse?

Wait taking nothing for months and than have surgery for months, and live with

Viagra for years hoping it will work not messing with my awful hormon levels?

I know you cant guarantee my anyting, or take responsibility for my further

steps, but I would be very grateful for advice. I see a lot of You with

knowledge and experience, and I m pretty sure, know more about complicated case

that most of endocrynologist in my country.

Thank You in Advance

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