RE: Question -- T Levels & Prostate Cancer

[Guest guest]

Lee men don't get cancer from high levels of T take younger men when T is up

there they don't get cancer. If you have cancer this could be a problem but

it's up in the air for now back in the day they use to say adding T to someone

could make the cancer worse. Yet there are no studies I have seen that prove

this.

Your body likes to be regular if you use a gel or cream everyday and cut back.

Your body is going to go nuts trying to keep your regular buy taking from other

hormones to keep your levels up. She is way off on this and all it will do is

set you back.

Co-Moderator

Phil

> From: Lee <hdbtwnurlegs2001@...>

> Subject: Question -- T Levels & Prostate Cancer

>

> Date: Tuesday, September 21, 2010, 3:31 PM

> My Dr. has changed my compounded

> T-gel prescription (T/Chrysin 10/15%, 0.5 ml/day) from daily

> to 5 days per week because she's concerned about the

> possibility of prostate cancer from elevated T levels.

>

> I'm 66 years young, and my last lab. test results were:

> Total T, 1421, Free 180.9,

> [the lab test results calculated] F/T amount of 1.27%.

> Estradiol was 49 giving a T/E2 ratio of 29:1 vs. what I'd

> like to have of 20:1

>

> I tried to talk her out of that with no luck, but I will be

> having a PSA test, along with a DRE, before I see her again

> on 09/27 to verify there's nothing present to be concerned

> about. 

>

> Is her concern based on current understandings of T levels

> in relation to prostate cancer potential valid, or has there

> been any recent research findings that question the " old

> wisdom " ?

>

> I would certainly appreciate any thoughts you may have on

> this topic.

>

> Lee

>

>

>

>

> ------------------------------------

>

>

[Guest guest]

Thanks Phil,

That's what I thought, but wanted to ask those of you with much more knowledge

than me on this topic. Unfortunately, my Dr. (she's an endocrinologist)

controls my prescription and seems to be (like many in the medical profession)

unwilling to consider anything suggested by an informed patient as some kind of

an assault on her ability to maintain control... I'll see if I can find some

peer-reviewed articles to give her that supports our position.

Lee

>

> > From: Lee <hdbtwnurlegs2001@...>

> > Subject: Question -- T Levels & Prostate Cancer

> >

> > Date: Tuesday, September 21, 2010, 3:31 PM

> > My Dr. has changed my compounded

> > T-gel prescription (T/Chrysin 10/15%, 0.5 ml/day) from daily

> > to 5 days per week because she's concerned about the

> > possibility of prostate cancer from elevated T levels.

> >

> > I'm 66 years young, and my last lab. test results were:

> > Total T, 1421, Free 180.9,

> > [the lab test results calculated] F/T amount of 1.27%.

> > Estradiol was 49 giving a T/E2 ratio of 29:1 vs. what I'd

> > like to have of 20:1

> >

> > I tried to talk her out of that with no luck, but I will be

> > having a PSA test, along with a DRE, before I see her again

> > on 09/27 to verify there's nothing present to be concerned

> > about. 

> >

> > Is her concern based on current understandings of T levels

> > in relation to prostate cancer potential valid, or has there

> > been any recent research findings that question the " old

> > wisdom " ?

> >

> > I would certainly appreciate any thoughts you may have on

> > this topic.

> >

> > Lee

> >

> >

> >

> >

> > ------------------------------------

> >

> >

[Guest guest]

Hi Lee,

Maybe this page from LEF may help your position that higher levels of T do

not cause prostate cancer:

http://www.lef.org/protocols/male_reproductive/male_hormone_restoration_02.h

tm

A Word about Testosterone and Prostate Disease

For more than 50 years, it has been thought that men should avoid

testosterone replacement therapy because testosterone increases the risk of

prostate disease, including BPH and prostate cancer. A look at the published

literature, however, reveals that this long-standing belief is actually a

myth.

In fact, a review of studies on the National Institutes of Health database

reveals that high testosterone levels are not associated with increased risk

of prostate cancer and, conversely, that low testosterone levels are not

protective against prostate cancer (Morgentaler A 2006). In one study (with

a 7-year follow-up) of more than 500 men, high levels of androgens were

associated with a decreased risk of aggressive prostate cancer, while there

was no change in the risk of nonaggressive prostate cancer. Overall, levels

of any steroid hormones (except estrogen) had no correlation to the risk of

prostate cancer (Severi G et al 2006).

Elevated estrogen levels, however, are frequently associated with BPH. As

readers of Life Extension magazine learned in late 1997, estrogen has been

identified as a factor behind the enlargement of the prostate gland that

affects so many older men. Compared to younger males, older males have much

more estradiol (a potent form of estrogen) than free testosterone because of

aromatase activity. These rising estrogen and declining androgen levels are

even more sharply defined in the prostate gland. With aging, estrogen levels

increase significantly in the prostate gland. Estrogen levels in prostate

gland tissues rise even higher in men who have BPH (Shibata Y et al 2000;

Gann PH et al 1995; Krieg M et al 1993).

Based on research, high levels of testosterone are not implicated in an

increased risk of developing either prostate cancer or BPH. However, among

men who already have these conditions, testosterone replacement therapy will

likely cause increased disease activity. For these reasons, it is important

that men who are considering hormone replacement therapy undergo frequent

screening for prostate cancer (with PSA testing and digital rectal exams).

If cancerous cells are present in the prostate, testosterone therapy will

likely produce a spike in PSA levels that will lead to a diagnosis of

prostate cancer.

Once a man actually has prostate cancer, testosterone therapy cannot be

recommended because most prostate cancer cells use testosterone to promote

the growth of the cancerous cells. Similarly, men with BPH should approach

testosterone replacement cautiously. It may be prudent for men with BPH who

are undergoing testosterone replacement therapy to also use a

5-alpha-reductase inhibitor (such as finasteride or dutasteride). These

drugs inhibit the synthesis of dihydrotestosterone (DHT), a metabolite of

testosterone that causes BPH. 5-Alpha-reductase inhibitors are a standard

part of prescription therapy for BPH. For more information on natural ways

to suppress BPH, please see the chapter on Benign Prostatic Hyperplasia.

From: [mailto: ]

On Behalf Of Lee

Sent: Wednesday, September 22, 2010 1:30 AM

Subject: Re: Question -- T Levels & Prostate Cancer

Thanks Phil,

That's what I thought, but wanted to ask those of you with much more

knowledge than me on this topic. Unfortunately, my Dr. (she's an

endocrinologist) controls my prescription and seems to be (like many in the

medical profession) unwilling to consider anything suggested by an informed

patient as some kind of an assault on her ability to maintain control...

I'll see if I can find some peer-reviewed articles to give her that supports

our position.

Lee

>

> > From: Lee <hdbtwnurlegs2001@...>

> > Subject: Question -- T Levels & Prostate Cancer

> >

<mailto: %40>

> > Date: Tuesday, September 21, 2010, 3:31 PM

> > My Dr. has changed my compounded

> > T-gel prescription (T/Chrysin 10/15%, 0.5 ml/day) from daily

> > to 5 days per week because she's concerned about the

> > possibility of prostate cancer from elevated T levels.

> >

> > I'm 66 years young, and my last lab. test results were:

> > Total T, 1421, Free 180.9,

> > [the lab test results calculated] F/T amount of 1.27%.

> > Estradiol was 49 giving a T/E2 ratio of 29:1 vs. what I'd

> > like to have of 20:1

> >

> > I tried to talk her out of that with no luck, but I will be

> > having a PSA test, along with a DRE, before I see her again

> > on 09/27 to verify there's nothing present to be concerned

> > about.

> >

> > Is her concern based on current understandings of T levels

> > in relation to prostate cancer potential valid, or has there

> > been any recent research findings that question the " old

> > wisdom " ?

> >

> > I would certainly appreciate any thoughts you may have on

> > this topic.

> >

> > Lee

> >

> >

> >

> >

> > ------------------------------------

> >

> >

[Guest guest]

Lee I wish you luck if you live in the USA Endo's are not good Dr.'s for this

problem you need to find a better Dr.

From the home page on the left side of the screen we have a Database section in

this we have a " Physician Reference " look in this and see if you can find a Dr.

in your area.

Also in the Files section we have a file " Finding A Male Hormone Dr. " read this

and make calls before seeing a new Dr. find out how many men the Dr. treats for

this problem and ask if he tests to find out why one is low and if he checks for

high Estradiol and treats it with Arimidex. Ask if one is Secondary dose he use

HCG.

Also try calling some Compounding Pharmacy like Collage.

http://www.collegepharmacy.com/menshealth/andropause.asp

Ask for the names of Dr.'s in your area that buy Testosterone from them. A lot

of men have good luck finding a better Dr. doing this.

Dr. Johh at www.allthingsmale.com use's this one.

ANEWrx

523 Parkway View Drive

Pittsburgh, PA 15205

877-788-8908 (ph)

877-788-8948 (fax)

Monday - Friday (9am - 6pm)

Saturday 10am - 2pm

www.ANEWrx.com

And if you can find a Dr. that is willing to work with him over the phone to

test and treat you he dose this.

Co-Moderator

Phil

> From: Lee <hdbtwnurlegs2001@...>

> Subject: Re: Question -- T Levels & Prostate Cancer

>

> Date: Wednesday, September 22, 2010, 2:30 AM

> Thanks Phil,

> That's what I thought, but wanted to ask those of you with

> much more knowledge than me on this topic. 

> Unfortunately, my Dr. (she's an endocrinologist) controls my

> prescription and seems to be (like many in the medical

> profession) unwilling to consider anything suggested by an

> informed patient as some kind of an assault on her ability

> to maintain control... I'll see if I can find some

> peer-reviewed articles to give her that supports our

> position.

> Lee

>

>

> >

> > > From: Lee <hdbtwnurlegs2001@...>

> > > Subject: Question -- T Levels

> & Prostate Cancer

> > >

> > > Date: Tuesday, September 21, 2010, 3:31 PM

> > > My Dr. has changed my compounded

> > > T-gel prescription (T/Chrysin 10/15%, 0.5 ml/day)

> from daily

> > > to 5 days per week because she's concerned about

> the

> > > possibility of prostate cancer from elevated T

> levels.

> > >

> > > I'm 66 years young, and my last lab. test results

> were:

> > > Total T, 1421, Free 180.9,

> > > [the lab test results calculated] F/T amount of

> 1.27%.

> > > Estradiol was 49 giving a T/E2 ratio of 29:1 vs.

> what I'd

> > > like to have of 20:1

> > >

> > > I tried to talk her out of that with no luck, but

> I will be

> > > having a PSA test, along with a DRE, before I see

> her again

> > > on 09/27 to verify there's nothing present to be

> concerned

> > > about. 

> > > 

> > > Is her concern based on current understandings of

> T levels

> > > in relation to prostate cancer potential valid,

> or has there

> > > been any recent research findings that question

> the " old

> > > wisdom " ?

> > > 

> > > I would certainly appreciate any thoughts you may

> have on

> > > this topic.

> > >

> > > Lee

> > >

> > >

> > >

> > >

> > > ------------------------------------

> > >

> > >

[Guest guest]

Men don't get prostate cancer from high testosterone. High estrogen yes;

testosterone no. Your doctor is many years behind on this and there is a lot of

research that offers proof contrary to her thinking. Many older men have higher

estrogen levels than their wives but estrogen levels in men can be controlled.

If high testosterone levels caused prostate cancer then lots of young men in

their 20's would be developing prostate cancer. W

> > >

> > > > From: Lee <hdbtwnurlegs2001@>

> > > > Subject: Question -- T Levels

> > & Prostate Cancer

> > > >

> > > > Date: Tuesday, September 21, 2010, 3:31 PM

> > > > My Dr. has changed my compounded

> > > > T-gel prescription (T/Chrysin 10/15%, 0.5 ml/day)

> > from daily

> > > > to 5 days per week because she's concerned about

> > the

> > > > possibility of prostate cancer from elevated T

> > levels.

> > > >

> > > > I'm 66 years young, and my last lab. test results

> > were:

> > > > Total T, 1421, Free 180.9,

> > > > [the lab test results calculated] F/T amount of

> > 1.27%.

> > > > Estradiol was 49 giving a T/E2 ratio of 29:1 vs.

> > what I'd

> > > > like to have of 20:1

> > > >

> > > > I tried to talk her out of that with no luck, but

> > I will be

> > > > having a PSA test, along with a DRE, before I see

> > her again

> > > > on 09/27 to verify there's nothing present to be

> > concerned

> > > > about. 

> > > > 

> > > > Is her concern based on current understandings of

> > T levels

> > > > in relation to prostate cancer potential valid,

> > or has there

> > > > been any recent research findings that question

> > the " old

> > > > wisdom " ?

> > > > 

> > > > I would certainly appreciate any thoughts you may

> > have on

> > > > this topic.

> > > >

> > > > Lee

> > > >

> > > >

> > > >

> > > >

> > > > ------------------------------------

> > > >

> > > >