Re: FYI : aromasin info - phil

[Guest guest]

Aromasinis easier on the liver, lowers SHBG and found that it improves my

complexion. I dont know why my complexion is better on Aromasin but many people

report the same. My skin is less oily and pimple outbreaks are much less. Since

it is easier on the liver its better for long term use and general health.

After long research I think aromasin out weights benefits to risk ratio to adex

hands down !!

>

> (aromasin) Exemestane is rapidly and extensively absorbed after

> oral administration, although animal data suggest that

> oral bioavailability might be incomplete due to first-

> pass hepatic metabolism. Food enhances absorption,

> resulting in plasma levels 40% higher than those

> observed under fasting conditions. Exemestane is

> extensively metabolised, viaoxidation (CYP3A4) and

> reduction (aldoketoreductase), to form many secondary

> metabolites, all of which are inactive or less active than

> the parent compound. It has a terminal elimination half-

> life of approximately 24 hours [3]. Both moderate and

> severe hepatic and renal impairment affect the

> pharmacokinetics of exemestane, but dose adjustments

> do not appear to be necessary [3].

>

[Guest guest]

Thanks but to save me time looking up what they are saying can you tell me what

they are saying and is this good or bad.

I am doing very good on this only doing 2 days on and one off.

Co-Moderator

Phil

> From: hardasnails1973 <hardasnails1973@...>

> Subject: FYI : aromasin info - phil

>

> Date: Thursday, January 20, 2011, 9:56 AM

> (aromasin) Exemestane is rapidly and

> extensively absorbed after

> oral administration, although animal data suggest that

> oral bioavailability might be incomplete due to first-

> pass hepatic metabolism. Food enhances absorption,

> resulting in plasma levels 40% higher than those

> observed under fasting conditions. Exemestane is

> extensively metabolised, viaoxidation (CYP3A4) and

> reduction (aldoketoreductase), to form many secondary

> metabolites, all of which are inactive or less active than

>

> the parent compound. It has a terminal elimination half-

> life of approximately 24 hours [3]. Both moderate and

> severe hepatic and renal impairment affect the

> pharmacokinetics of exemestane, but dose adjustments

> do not appear to be necessary [3]. 

>      

>

>

>

>

> ------------------------------------

>

>

[Guest guest]

Wow you had me going I thought this was bad news and you know my skin is not

oily anymore. I am even finding my feet are now very dry and look white.

I can't believe how much better I feel on Armoasin and if I feel low after

taking it in the morning by night time every thing is back to working. I still

have wood every night been on this 9 days now.

I am even seeing less muscle pain from the statin drug damage.

Co-Moderator

Phil

> From: hardasnails1973 <hardasnails1973@...>

> Subject: Re: FYI : aromasin info - phil

>

> Date: Thursday, January 20, 2011, 10:20 AM

> Aromasinis easier on the liver,

> lowers SHBG and found that it improves my complexion. I dont

> know why my complexion is better on Aromasin but many people

> report the same. My skin is less oily and pimple outbreaks

> are much less. Since it is easier on the liver its better

> for long term use and general health.

>

>

> After long research I think aromasin out weights benefits

> to risk ratio to adex hands down !!

>

>

> >

> > (aromasin) Exemestane is rapidly and extensively

> absorbed after

> > oral administration, although animal data suggest that

>

> > oral bioavailability might be incomplete due to first-

>

> > pass hepatic metabolism. Food enhances absorption,

> > resulting in plasma levels 40% higher than those

> > observed under fasting conditions. Exemestane is

> > extensively metabolised, viaoxidation (CYP3A4) and

> > reduction (aldoketoreductase), to form many secondary

>

> > metabolites, all of which are inactive or less active

> than

> > the parent compound. It has a terminal elimination

> half-

> > life of approximately 24 hours [3]. Both moderate and

>

> > severe hepatic and renal impairment affect the

> > pharmacokinetics of exemestane, but dose adjustments

> > do not appear to be necessary [3].

> >

>

>

>

>

> ------------------------------------

>

>

[Guest guest]

Phil,

What dose are you taking?

> > >

> > > (aromasin) Exemestane is rapidly and extensively

> > absorbed after

> > > oral administration, although animal data suggest that

> >

> > > oral bioavailability might be incomplete due to first-

> >

> > > pass hepatic metabolism. Food enhances absorption,

> > > resulting in plasma levels 40% higher than those

> > > observed under fasting conditions. Exemestane is

> > > extensively metabolised, viaoxidation (CYP3A4) and

> > > reduction (aldoketoreductase), to form many secondary

> >

> > > metabolites, all of which are inactive or less active

> > than

> > > the parent compound. It has a terminal elimination

> > half-

> > > life of approximately 24 hours [3]. Both moderate and

> >

> > > severe hepatic and renal impairment affect the

> > > pharmacokinetics of exemestane, but dose adjustments

> > > do not appear to be necessary [3].

> > >

> >

> >

> >

> >

> > ------------------------------------

> >

> >

[Guest guest]

My scirpt is for 25 mgs I use a pill cutter and cut them in half the the days I

take a half of a pill.

I do shots every 3 days of Test C on the morning of my shot I started at 25 mgs.

Then the next day I don't do any kind of shot. So for the first week I needed

to do 25 mgs everyday for about 6 days then I started feeling my levels going

down to low. So the day after my Test C shot I did not take it. I take my

Aromasin in the morning at about 4 to 5 am because E2 and T are the highest in

the morning when one wakes. So when I am to high this is when I feel bad. I do

an HCG shot the day before my Test C shot. So now that I have been on it 9 days

I am finding I get by on one half the pill on the day I do my HCG shots and the

day I do my Test C shot then I am skiping a day. It is still very new for me

and I am adjusting by how I feel I can tell when I go low or start to go high.

Like the first morning day I skipped it I needed to take a 12.5 or half a pill

by dinner time I got this wave of panic and stared sweating with sore and hard

nipples. So I

knew I was going back up it worked in about 20 min.'s.

It is still a work in progress.

Co-Moderator

Phil

> From: master_trancer <master_trancer@...>

> Subject: Re: FYI : aromasin info - phil

>

> Date: Thursday, January 20, 2011, 10:59 AM

> Phil,

>

> What dose are you taking?

>

>

>

> > > >

> > > > (aromasin) Exemestane is rapidly and

> extensively

> > > absorbed after

> > > > oral administration, although animal data

> suggest that

> > >

> > > > oral bioavailability might be incomplete due

> to first-

> > >

> > > > pass hepatic metabolism. Food enhances

> absorption,

> > > > resulting in plasma levels 40% higher than

> those

> > > > observed under fasting conditions.

> Exemestane is

> > > > extensively metabolised, viaoxidation

> (CYP3A4) and

> > > > reduction (aldoketoreductase), to form many

> secondary

> > >

> > > > metabolites, all of which are inactive or

> less active

> > > than

> > > > the parent compound. It has a terminal

> elimination

> > > half-

> > > > life of approximately 24 hours [3]. Both

> moderate and

> > >

> > > > severe hepatic and renal impairment affect

> the

> > > > pharmacokinetics of exemestane, but dose

> adjustments

> > > > do not appear to be necessary [3].

> > > >

> > >

> > >

> > >

> > >

> > > ------------------------------------

> > >

> > >

[Guest guest]

i would do 12.5 EOD for a week then increase or decrease. Smaller dosage daily

is better since drug life is about 9 hours.

> > > > >

> > > > > (aromasin) Exemestane is rapidly and

> > extensively

> > > > absorbed after

> > > > > oral administration, although animal data

> > suggest that

> > > >

> > > > > oral bioavailability might be incomplete due

> > to first-

> > > >

> > > > > pass hepatic metabolism. Food enhances

> > absorption,

> > > > > resulting in plasma levels 40% higher than

> > those

> > > > > observed under fasting conditions.

> > Exemestane is

> > > > > extensively metabolised, viaoxidation

> > (CYP3A4) and

> > > > > reduction (aldoketoreductase), to form many

> > secondary

> > > >

> > > > > metabolites, all of which are inactive or

> > less active

> > > > than

> > > > > the parent compound. It has a terminal

> > elimination

> > > > half-

> > > > > life of approximately 24 hours [3]. Both

> > moderate and

> > > >

> > > > > severe hepatic and renal impairment affect

> > the

> > > > > pharmacokinetics of exemestane, but dose

> > adjustments

> > > > > do not appear to be necessary [3].

> > > > >

> > > >

> > > >

> > > >

> > > >

> > > > ------------------------------------

> > > >

> > > >

[Guest guest]

That was my thinking but trying this when I started 12.5 was not enought to last

the day. This is way after talking to you on the phone how your lowering your

HCG and using it only for LH not T levels I am cutting back on HCG to help lower

E2 levels. And I am going to try to lower my Test C down to what would = 150

mgs / weeks. Or 60 mgs every 3 days if this keeps my TT levels above 600 and I

feel OK I am going to hold at this dose I did very good for a long time but at

that time my Test C was Depo a brand name not sure about all the 1 mls. vials

they are sending me of Generic Test C.

Co-Moderator

Phil

> From: hardasnails1973 <hardasnails1973@...>

> Subject: Re: FYI : aromasin info - phil

>

> Date: Thursday, January 20, 2011, 11:29 AM

> i would do 12.5 EOD  for a week

> then increase or decrease. Smaller dosage daily is better

> since drug life is about 9 hours.

>

>

> > > > > >

> > > > > > (aromasin) Exemestane is rapidly

> and

> > > extensively

> > > > > absorbed after

> > > > > > oral administration, although

> animal data

> > > suggest that

> > > > >

> > > > > > oral bioavailability might be

> incomplete due

> > > to first-

> > > > >

> > > > > > pass hepatic metabolism. Food

> enhances

> > > absorption,

> > > > > > resulting in plasma levels 40%

> higher than

> > > those

> > > > > > observed under fasting

> conditions.

> > > Exemestane is

> > > > > > extensively metabolised,

> viaoxidation

> > > (CYP3A4) and

> > > > > > reduction (aldoketoreductase), to

> form many

> > > secondary

> > > > >

> > > > > > metabolites, all of which are

> inactive or

> > > less active

> > > > > than

> > > > > > the parent compound. It has a

> terminal

> > > elimination

> > > > > half-

> > > > > > life of approximately 24 hours

> [3]. Both

> > > moderate and

> > > > >

> > > > > > severe hepatic and renal

> impairment affect

> > > the

> > > > > > pharmacokinetics of exemestane,

> but dose

> > > adjustments

> > > > > > do not appear to be necessary

> [3].

> > > > > >

> > > > >

> > > > >

> > > > >

> > > > >

> > > > > ------------------------------------

> > > > >

> > > > >