Guest guest Posted July 23, 2000 Report Share Posted July 23, 2000 Adding to Dr The best way to determine adrenal support vis-a-vis DHEA, pregnenalone, progesterone, cortisol, smooth muscle relaxing herbs, Vit C, B5/B6, adaptogens, phosphatidyl serine and lifestyle changes is thru the Adrenal Stress Index. A minimal ASI consists of an AM DHEA, progesterone, and an early AM and late PM cortisol , all via saliva. (Those who wish to know more, and wish to interpret their own results as well, can see the Article Archives at RxforWellness. ) Fortunately , such tests can be ordered on-line. Vitally yours, Dr. H. Maher, A.B.A.A.H.P. Editor, " Longevity News " subscribe@... http://www.RxforWellness.com " Your FREE Anti-Aging Home Study Course On-Line! " Re: prognenolone > DHEA tends to suppress cortisol. Balance of all sterol hormones is > essential. Excess or inadequate both cause dysfunction. They all are > interactive. > R , MD > > ------------------------------------------------------------------------ > Special Offer-Earn 300 Points from MyPoints.com for trying @Backup > Get automatic protection and access to your important computer files. > Install today: > 1/6347/14/_/164625/_/964364047/ > ------------------------------------------------------------------------ > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 23, 2000 Report Share Posted July 23, 2000 Dale, > Gordo, also thanks. I hadn't thought about the cortisol and that > would explain quite a bit. In think so too. At least I can't think of any other reasonable explanation for pregnenolone causing fatigue. My detractors here have offered no better explanation. > On another note--I have been on the hGH for about two months now and > am not getting the quality sleep that others have talked about. ... Any > comments would be appreciated Personally I've never noticed any significant change in my sleeping quality or patterns from GH. However I do notice that doses in excess of 2 iu taken in the evening can keep me awake. It is energizing for me. -gts Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2003 Report Share Posted May 6, 2003 What is it that you all take this for?? ~Leah Love Chinchillas?? Check out Chinchilla Fluff & Stuff for GREAT chinchilla collectibles!!! http://www.cafeshops.com/chinchillastuff Also check out my other online store " Animal Art " http://www.cafeshops.com/petsandwildlife pregnenolone Here's some info I found on pregnenolone Pregnenolone is the ultimate parent steroid compound. All steroid hormones in the body (including cortisone, testosterone, estrogen, progesterone, DHEA, and others) are produced from pregnenolone, which in turn is synthesized from cholesterol. Progesterone and DHEA are also parent steroids in the sense that they can give rise to a number of other steroid species, but only pregnenolone is the ultimate precursor of all other steroid hormones. Levels of endogenous (i. e. made in the body) pregnenolone decline with age, as do levels of DHEA. However, the normal levels of pregnenolone at various ages for each gender in humans have not been as clearly established as with DHEA. The pathways from pregnenolone to the many other steroids (and the interrelationships among these steroids) is complex. While some benefits can be attributed to the relatively direct action of pregnenolone (for example, as a memory enhancer), many other benefits are a result of one or more of pregnenolone's direct or indirect " offspring². There seem to be many factors that determine how much of the pregnenolone in the body is: 1) used as pregnenolone, 2) converted to DHEA and used as DHEA, 3) converted to progesterone and used as progesterone, and 4) converted to either DHEA or progesterone and then converted into one or more other hormones (e.g. cortisol, testosterone and the venous estrogens). One of these factors is one's gender. Other factors are more variable throughout life, such as the many factors referred to collectively as " life-style² (e.g. diet, stress level, exercise habits), the presence of one or more diseases/health conditions, and stage of life (e.g. post-menopausal). Arthritis One health condition is rheumatoid arthritis. Since it is a precursor to the production of cortisol in the body pregnenolone was used as early as the 1940s as a treatment for rheumatoid arthritis. In daily doses ranging from 50 mg to 700 mg, pregnenolone was found to be effective for this condition and to be much safer than the corticoids, salicylates, gold, and other drugs used as treatments at the time. Daily doses of pregnenolone above 200 mg appeared to be more effective than those below 200 mg. (son) Fatigue In the mid 1940s, several studies indicated that a daily dose of 50 mg of pregnenolone reduced fatigue and stress among factory workers, airline pilots and other subjects (Pincus) Today, there are millions of people who suffer from stress and fatigue who may find relief with pregnenolone. Memory Enhancement Pregnenolone has been found to play an important role in the acquisition of knowledge and the long term memory of learned behavior. (DeWied 1976, 1977). In a study with rats by Flood et al. (1995), pregnenolone was found to enhance memory at doses far lower than doses required of other steroids or steroid precursors, including DHEA. Pregnenolone blocks the inhibitory amino acids glycine and gamma-aminobutyric acid (GABA), as well as non-NMDA glutamate. As a result, pregnenolone helps to regulate the balance between excitation and inhibition, a major dynamic in the central nervous system. (Wu) Nerve Regeneration Administration of either pregnenolone or progesterone in mice also promoted myelin formation during nerve regeneration. (Koenig) (The myclin sheath is a membrane that protects or insulates various parts of the nerve cell, preventing short-circuiting or loss of neural transmission.) This suggests a possible role for supplemental pregnenolone in conditions involving demyelination, such as multiple sclerosis. Women's Health Issues Many women have been recently turning to natural products to deal with women's health probLems. Since pregnenolone converts to DHEA and then to estrogens, pregnenolone provides a safe estrogen replacement therapy for post-menopausal women. It also provides a natural source of progesterone, another important hormone for the health of the female reproductive system. Progesterone can help to control PMS. Relative to DHEA (particularly in large amounts), pregnenolone is less likely to create masculinizing effects (e.g. facial hair) in women because it is less likely to increase testosterone levels in women. TOXICITY / SAFETY: Pregnenolone does not seem to have any negative side effects. However, please consult your health care provider if you are pregnant or nursing before using. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2003 Report Share Posted May 6, 2003 Hormonal problems that the doctor believes are caused by a stressed system. Heidi Watterson Hutton Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2003 Report Share Posted May 6, 2003 Bravo,Leah!!!! Thanks for all that info.!! Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 14, 2003 Report Share Posted May 14, 2003 thye have to write that stuff on there. Most likely your doctor will have no clue, usually they tell you the OTC safe stuff is dangerous so here take this prozac and xanax. just try it! I never have though, I take DHEA and progesterone cream. Gracia > I got some pregnenolone today. It says on the bottle to consult a physician before taking and not to take if under 40 years of ago. However this page http://www.reach4life.com/1552a.html says that there are no side affects. Anyone else taking this?? I really want to start but should I ask my doc first, who I haven't seen in over 5 years by the way. > ~Leah > Love Chinchillas?? Check out Chinchilla Fluff & Stuff for GREAT chinchilla collectibles!!! http://www.cafeshops.com/chinchillastuff > Also check out my other online store " Animal Art " http://www.cafeshops.com/petsandwildlife > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 15, 2004 Report Share Posted May 15, 2004 A while back there was a discussion as to whether coconut oil could cause racing heart or palpitations. This is what I found. http://www.mercola.com/2001/mar/24/coconut_oil.htm As far as the evidence goes, it suggests that coconut oil, added regularly to a balanced diet, lowers cholesterol to normal by promoting its conversion into pregnenolone. Lost the reference to this one sorry: Our major uncertainty at this time involves the long-term use of pregnenolone as hormone replacement therapy, especially if high doses are used. Pregnenolone can also cause heart palpitations in high doses. With time, as more and more people use this hormone, we'll have a fuller understanding of its benefits and side effects. Those who have already found pregnenolone to be helpful in terms of mood elevation, stress reduction, arthritis help, visual and auditory enhancement, and so forth, but are concerned about unknown long-term effects, may feel more comfortable using pregnenolone only as needed and frequently taking time off from it. Taking these " hormone holidays " will mitigate any potential unknown risks. Daily use of pregnenolone over prolonged periods should be no more than 1 to 3 mg unless you are closely followed by a health care practitioner familiar with the clinical uses of this hormone. Current dosage available over the counter, such as 25, 50, or 100 mg are TOO high. If you purchase a 10 mg pill or capsule, take a portion of it if you plan to take it on a regular basis. So I guess the answer is yes coconut oil is good for you but too much can cause side effects in some people who are sensitive. I seem to be sensitive. I love coconut oil and will not give it up. . .but now I know I eat to much without without heart palpitations. Take Care Sherry Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 18, 2008 Report Share Posted September 18, 2008 cortisol high by what standard/test? my cortisol test results were blood--normal saliva--high 24 hr urine from http://www.antibodyassay.com ---low my health history of 50 yrs untreated hypo should have automatically qualified me for taking cortisol (which I still take). Gracia , I'm listening to Kurt Woeller's lectures on chronic stress illness and he talks about "pregnenolone steal".The first place to look for more info was on this site for past messages and found some useful info from you. Thank you.Wanted to ask you if my understaning of this is in the ball park: Chronic stresses (my sons and I have pesticides and heavy metals) produce more cortisol which hugely affects hormone balance including thyroid health. The body has a mechanism to lower metabolism when cortisol runs high so your adrenals won't burn out. Is it possible when taking thyroid meds, which revs up your metabolism, you could inadvertantly send your adrenals crashing because the cortisol is still high? No virus found in this incoming message.Checked by AVG - http://www.avg.com Version: 8.0.169 / Virus Database: 270.6.21/1678 - Release Date: 9/18/2008 9:01 AM Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 19, 2008 Report Share Posted September 19, 2008 I think it is possible to send your adrenals crashing because you have increased the metabolic rate with the increase in T3. pregnenolone > , I'm listening to Kurt Woeller's lectures on chronic stress > illness and he talks about " pregnenolone steal " . > The first place to look for more info was on this site for past > messages and found some useful info from you. Thank you. > Wanted to ask you if my understaning of this is in the ball park: > Chronic stresses (my sons and I have pesticides and heavy metals) > produce more cortisol which hugely affects hormone balance including > thyroid health. The body has a mechanism to lower metabolism when > cortisol runs high so your adrenals won't burn out. Is it possible > when taking thyroid meds, which revs up your metabolism, you could > inadvertantly send your adrenals crashing because the cortisol is still > high? > > > > > > ------------------------------------ > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 26, 2009 Report Share Posted November 26, 2009 Pregneolone upregulates the XMVR virus. R. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 26, 2009 Report Share Posted November 26, 2009 , Is the reason pregnenolone upregulates XMRV because it's a hormone? Do you know if Vitamin D has any impact specifically on XMRV? Thanks ________________________________ From: Rice <taxdoc@...> " " < > Sent: Thu, November 26, 2009 1:44:09 PM Subject: Re:Pregnenolone  Pregneolone upregulates the XMVR virus. R. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 2, 2010 Report Share Posted February 2, 2010 depending upon individual biochemistry pregnenolone can go into a number one of path ways DHEA being one of them > > It is my understanding that pregnenolone is a precursor to DHEA, anyone disagree or agree, or is there more. I read Dr. likes it. > thanks, david a > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 4, 2010 Report Share Posted February 4, 2010 I use PREG to " backfill " the pathways, since TRT itself can inhibit same. It's also possible to treat Adrenal Fatigue with PREG only. Use a TD. Orals can 5-AR in the liver to a substance that looks like valium to the brain. Be well! Regards, Crisler, DO Anti-Aging Medicine The information contained in this message is intended only for the personal and confidential use of the recipient(s) named above, and is protected by state and federal law. If the reader of this message is not the intended recipient or an agent responsible for delivering it to the intended recipient, you are hereby notified that you have received this document in error and that any review, dissemination, distribution, or copying of this message is strictly prohibited. If you have received this communication in error, please notify us immediately, and delete the original message. We would certainly do the same for you. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 11, 2010 Report Share Posted November 11, 2010 Please take this topic to the Iodine Off Topic Group, link is posted at the bottom of this page. Thank you. Kathleen Pregnenolone Hi,I had been given a suggestion that pregnenolone might help me. I will receive my order of 10 mg sublingual tomorrow. Can someone please tell me the best way to take it. With food/without. If it should be taken with or not near any specific supplement. I thought I'd start with 1/4 or 1/2 dose or consider any suggestion.I also ordered 's Naturopathic, Adrenal Xtra, an herbal supplement with Ashwagandha Root (Withania somnifera), Rhodiola Rosea Root Extract (3% rosavins), Rhodiola Rosea Root, Licorice Root (Glycyrrhiza glabra) plus 1500 mg B5.Any suggestions on which I should start first? I really appreciate all of your(collective)experience and help. J Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 7, 2010 Report Share Posted December 7, 2010 Hello everyone..Does anyone know if its ok to take Pregnenolone while Im on Androgel?My libido is not enough for me and I thought this may boost it possibly?thanks Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.