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Question re Lab Corp and Quest

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What methods due these labs use to determine total testosterone?

liquid chromatography–tandem mass spectrometry, automated platform immunoassays

or some other method?

I ask because according to this study

http://biomedgerontology.oxfordjournals.org/content/66A/1/122.full

Total testosterone levels by liquid chromatography–tandem mass spectrometry were

on average & #8764;130 ng/dL higher than those obtained by the automated platform

immunoassays. It is possible that serum level targets may differ when other

assays are used to quantify serum testosterone levels.

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But isn't that why each lab has its own range?

>

> What methods due these labs use to determine total testosterone?

>

> liquid chromatography–tandem mass spectrometry, automated platform

immunoassays or some other method?

>

> I ask because according to this study

>

> http://biomedgerontology.oxfordjournals.org/content/66A/1/122.full

>

> Total testosterone levels by liquid chromatography–tandem mass spectrometry

were on average & #8764;130 ng/dL higher than those obtained by the automated

platform immunoassays. It is possible that serum level targets may differ when

other assays are used to quantify serum testosterone levels.

>

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If we know how the levels are determined (what methodology the lab uses) we

might have a better understanding of their ranges

> >

> > What methods due these labs use to determine total testosterone?

> >

> > liquid chromatography–tandem mass spectrometry, automated platform

immunoassays or some other method?

> >

> > I ask because according to this study

> >

> > http://biomedgerontology.oxfordjournals.org/content/66A/1/122.full

> >

> > Total testosterone levels by liquid chromatography–tandem mass spectrometry

were on average & #8764;130 ng/dL higher than those obtained by the automated

platform immunoassays. It is possible that serum level targets may differ when

other assays are used to quantify serum testosterone levels.

> >

>

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