Guest guest Posted January 31, 2011 Report Share Posted January 31, 2011 What methods due these labs use to determine total testosterone? liquid chromatography–tandem mass spectrometry, automated platform immunoassays or some other method? I ask because according to this study http://biomedgerontology.oxfordjournals.org/content/66A/1/122.full Total testosterone levels by liquid chromatography–tandem mass spectrometry were on average & #8764;130 ng/dL higher than those obtained by the automated platform immunoassays. It is possible that serum level targets may differ when other assays are used to quantify serum testosterone levels. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 31, 2011 Report Share Posted January 31, 2011 But isn't that why each lab has its own range? > > What methods due these labs use to determine total testosterone? > > liquid chromatography–tandem mass spectrometry, automated platform immunoassays or some other method? > > I ask because according to this study > > http://biomedgerontology.oxfordjournals.org/content/66A/1/122.full > > Total testosterone levels by liquid chromatography–tandem mass spectrometry were on average & #8764;130 ng/dL higher than those obtained by the automated platform immunoassays. It is possible that serum level targets may differ when other assays are used to quantify serum testosterone levels. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 31, 2011 Report Share Posted January 31, 2011 If we know how the levels are determined (what methodology the lab uses) we might have a better understanding of their ranges > > > > What methods due these labs use to determine total testosterone? > > > > liquid chromatography–tandem mass spectrometry, automated platform immunoassays or some other method? > > > > I ask because according to this study > > > > http://biomedgerontology.oxfordjournals.org/content/66A/1/122.full > > > > Total testosterone levels by liquid chromatography–tandem mass spectrometry were on average & #8764;130 ng/dL higher than those obtained by the automated platform immunoassays. It is possible that serum level targets may differ when other assays are used to quantify serum testosterone levels. > > > Quote Link to comment Share on other sites More sharing options...
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