Guest guest Posted February 22, 2011 Report Share Posted February 22, 2011 Good website but it does have some misinformation contained within it. On Tue, Feb 22, 2011 at 7:15 PM, Barb <baba@...> wrote: > > > Check out TiredThyroid.com, a new website that covers the most common > topics discussed on the forums, with medical journal references to convince > your doctor that " you CAN believe what you read on the internet! " > > More info on the rT3 debate: http://tiredthyroid.com/rt3.html > > Why you shouldn't donate blood more than twice a year: > http://tiredthyroid.com/mens-hormones.html > > Why you shouldn't trust a TSH to tell if you're hypothyroid: > http://tiredthyroid.com/tsh.html > > Barb > > > -- Mike Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 22, 2011 Report Share Posted February 22, 2011 Can you elaborate on what you thought was misinformation? > > > > > > > Check out TiredThyroid.com, a new website that covers the most common > > topics discussed on the forums, with medical journal references to convince > > your doctor that " you CAN believe what you read on the internet! " > > > > More info on the rT3 debate: http://tiredthyroid.com/rt3.html > > > > Why you shouldn't donate blood more than twice a year: > > http://tiredthyroid.com/mens-hormones.html > > > > Why you shouldn't trust a TSH to tell if you're hypothyroid: > > http://tiredthyroid.com/tsh.html > > > > Barb > > > > > > > > > > -- > Mike > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 22, 2011 Report Share Posted February 22, 2011 Sure, the only thing I found was the paragraph stating that the brain needs T4. My understanding was that scientists used to think that only T4 crossed the blood brain barrir but they later discovered that T3 does as well. So, theoretically, it would follow logically that the brain wouldn't require T4 supplementation because it would just turn it into T3, which you could just supplement endogenously On Tue, Feb 22, 2011 at 8:09 PM, Barb <baba@...> wrote: > > > Can you elaborate on what you thought was misinformation? > > > > > > > > > > > > > > Check out TiredThyroid.com, a new website that covers the most common > > > topics discussed on the forums, with medical journal references to > convince > > > your doctor that " you CAN believe what you read on the internet! " > > > > > > More info on the rT3 debate: http://tiredthyroid.com/rt3.html > > > > > > Why you shouldn't donate blood more than twice a year: > > > http://tiredthyroid.com/mens-hormones.html > > > > > > Why you shouldn't trust a TSH to tell if you're hypothyroid: > > > http://tiredthyroid.com/tsh.html > > > > > > Barb > > > > > > > > > > > > > > > > > -- > > Mike > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 22, 2011 Report Share Posted February 22, 2011 Yes, both T4 AND T3 cross the barrier, but the brain works best with " fresh T3 " that it just created from T4. There may be more to T4 in the brain than just the conversion aspect, because some people (me included), can attest to being brain-dead without T4 (even with the T3 cranked up). Dr. no discusses T4 in the brain here: Brain thyroid hormone levels and T3 to T4 ratios are going to be determined at several levels. For example, the number and types and location of thyroid transporters determines what amount of thyroid hormone gets through. Variations in the genes for the thyroid transporter molecules will determine how effective they are and how selective they are for T3 or T4 transport - creating a difference between Blood and Brain concentrations of Thyroid hormones. Variations in Astrocyte and Tanycyte Diodinase D2 production will determine T3 to T4 conversions in the brain, which may be different from the blood. etc. --- From my point of view, given the differences that can arise in blood versus brain levels of thyroid hormone and thyroid hormone conversion, it is important to consider in some patients to not only optimize T3 but to also optimize T4 levels. This is important, for example, in mood disorders. Here, the difference between T3 and T4 treatment becomes apparent. In major depressive disorder, historically, T3 is a more effective treatment than T4 in reducing depressive symptoms. Spectulating: perhaps T4 to T3 conversion in the brain's astrocytes and tanycytes is impaired by lack of D2 Diodinase production, among other possible problems in brain thyroid hormone metabolism. In bipolar disorder, historically, T4 is much more effective than T3 in stabilizing mood. T4 may be used medicinally to reach " hyperthyroid " levels - based on TSH measurements - in psychiatry to stabilize mood in bipolar disorder. Speculating: perhaps, in bipolar disorder, there is a gene mutation in one of the thyroid transport molecules which selectively impairs T3 transport. If a person is having problems with a T3 treatment or Armour Thyroid Treatment (which is primarily a T3 treatment), then perhaps adding a T4 treatment would be useful. Some patients benefit from combinations of thyroid treatments (e.g. T3 + T4, Armour Thyroid + Levothyroxine) better than single treatments alone. __________________ Romeo B. no, MD, physician, psychiatrist > > > > > > > > > > > > > > > Check out TiredThyroid.com, a new website that covers the most common > > > > topics discussed on the forums, with medical journal references to > > convince > > > > your doctor that " you CAN believe what you read on the internet! " > > > > > > > > More info on the rT3 debate: http://tiredthyroid.com/rt3.html > > > > > > > > Why you shouldn't donate blood more than twice a year: > > > > http://tiredthyroid.com/mens-hormones.html > > > > > > > > Why you shouldn't trust a TSH to tell if you're hypothyroid: > > > > http://tiredthyroid.com/tsh.html > > > > > > > > Barb > > > > > > > > > > > > > > > > > > > > > > > > -- > > > Mike > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 22, 2011 Report Share Posted February 22, 2011 Thanks. Nice reading, Barb. I read the RT3 article and really liked the compiling of basically everyone's opinion on the matter. I don't know how the ones on T3 only do it. I too was mentally impaired on just T3. But, I keep my mouth shut as I guess plenty on T3 only aren't brain dead!? I also had eyebrows fail to regrow right on T3 only, so the hair/T4 thing was interesting. My father and I both feel tired when we don't have enough T4, in addition. T4 is obviously there for a reason... -Nigel On 22 February 2011 21:23, Barb <baba@...> wrote: > > > Yes, both T4 AND T3 cross the barrier, but the brain works best with " fresh > T3 " that it just created from T4. There may be more to T4 in the brain than > just the conversion aspect, because some people (me included), can attest to > being brain-dead without T4 (even with the T3 cranked up). Dr. no > discusses T4 in the brain here: > > Brain thyroid hormone levels and T3 to T4 ratios are going to be determined > at several levels. > > For example, the number and types and location of thyroid transporters > determines what amount of thyroid hormone gets through. > > Variations in the genes for the thyroid transporter molecules will > determine how effective they are and how selective they are for T3 or T4 > transport - creating a difference between Blood and Brain concentrations of > Thyroid hormones. > > Variations in Astrocyte and Tanycyte Diodinase D2 production will determine > T3 to T4 conversions in the brain, which may be different from the blood. > > etc. > > --- > > From my point of view, given the differences that can arise in blood versus > brain levels of thyroid hormone and thyroid hormone conversion, it is > important to consider in some patients to not only optimize T3 but to also > optimize T4 levels. > > This is important, for example, in mood disorders. Here, the difference > between T3 and T4 treatment becomes apparent. > > In major depressive disorder, historically, T3 is a more effective > treatment than T4 in reducing depressive symptoms. Spectulating: perhaps T4 > to T3 conversion in the brain's astrocytes and tanycytes is impaired by lack > of D2 Diodinase production, among other possible problems in brain thyroid > hormone metabolism. > > In bipolar disorder, historically, T4 is much more effective than T3 in > stabilizing mood. T4 may be used medicinally to reach " hyperthyroid " levels > - based on TSH measurements - in psychiatry to stabilize mood in bipolar > disorder. Speculating: perhaps, in bipolar disorder, there is a gene > mutation in one of the thyroid transport molecules which selectively impairs > T3 transport. > > If a person is having problems with a T3 treatment or Armour Thyroid > Treatment (which is primarily a T3 treatment), then perhaps adding a T4 > treatment would be useful. Some patients benefit from combinations of > thyroid treatments (e.g. T3 + T4, Armour Thyroid + Levothyroxine) better > than single treatments alone. > __________________ > Romeo B. no, MD, physician, psychiatrist > > > > > > > > > > > > > > > > > > > > > > Check out TiredThyroid.com, a new website that covers the most > common > > > > > topics discussed on the forums, with medical journal references to > > > convince > > > > > your doctor that " you CAN believe what you read on the internet! " > > > > > > > > > > More info on the rT3 debate: http://tiredthyroid.com/rt3.html > > > > > > > > > > Why you shouldn't donate blood more than twice a year: > > > > > http://tiredthyroid.com/mens-hormones.html > > > > > > > > > > Why you shouldn't trust a TSH to tell if you're hypothyroid: > > > > > http://tiredthyroid.com/tsh.html > > > > > > > > > > Barb > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > -- > > > > Mike > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 22, 2011 Report Share Posted February 22, 2011 Thanks Nigel. So did your eyebrows come back when you added T4? I still can't figure mine out. Hole in the middle. > > > > > > > > > > > > > > > > > > > > > > > Check out TiredThyroid.com, a new website that covers the most > > common > > > > > > topics discussed on the forums, with medical journal references to > > > > convince > > > > > > your doctor that " you CAN believe what you read on the internet! " > > > > > > > > > > > > More info on the rT3 debate: http://tiredthyroid.com/rt3.html > > > > > > > > > > > > Why you shouldn't donate blood more than twice a year: > > > > > > http://tiredthyroid.com/mens-hormones.html > > > > > > > > > > > > Why you shouldn't trust a TSH to tell if you're hypothyroid: > > > > > > http://tiredthyroid.com/tsh.html > > > > > > > > > > > > Barb > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > -- > > > > > Mike > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 22, 2011 Report Share Posted February 22, 2011 You guys should read up on Dr. Lowes' stuff. He has some really interesting points and research on why T3 only medication can be used alone and for life. However, everyone is different and everyone requires specific treatments for their body chemistry. On Tue, Feb 22, 2011 at 9:47 PM, Nigel <nachonigel@...> wrote: > Thanks. Nice reading, Barb. I read the RT3 article and really liked the > compiling of basically everyone's opinion on the matter. > > I don't know how the ones on T3 only do it. I too was mentally impaired on > just T3. But, I keep my mouth shut as I guess plenty on T3 only aren't > brain > dead!? I also had eyebrows fail to regrow right on T3 only, so the hair/T4 > thing was interesting. My father and I both feel tired when we don't have > enough T4, in addition. T4 is obviously there for a reason... > > -Nigel > > On 22 February 2011 21:23, Barb <baba@...> wrote: > > > > > > > Yes, both T4 AND T3 cross the barrier, but the brain works best with > " fresh > > T3 " that it just created from T4. There may be more to T4 in the brain > than > > just the conversion aspect, because some people (me included), can attest > to > > being brain-dead without T4 (even with the T3 cranked up). Dr. no > > discusses T4 in the brain here: > > > > Brain thyroid hormone levels and T3 to T4 ratios are going to be > determined > > at several levels. > > > > For example, the number and types and location of thyroid transporters > > determines what amount of thyroid hormone gets through. > > > > Variations in the genes for the thyroid transporter molecules will > > determine how effective they are and how selective they are for T3 or T4 > > transport - creating a difference between Blood and Brain concentrations > of > > Thyroid hormones. > > > > Variations in Astrocyte and Tanycyte Diodinase D2 production will > determine > > T3 to T4 conversions in the brain, which may be different from the blood. > > > > etc. > > > > --- > > > > From my point of view, given the differences that can arise in blood > versus > > brain levels of thyroid hormone and thyroid hormone conversion, it is > > important to consider in some patients to not only optimize T3 but to > also > > optimize T4 levels. > > > > This is important, for example, in mood disorders. Here, the difference > > between T3 and T4 treatment becomes apparent. > > > > In major depressive disorder, historically, T3 is a more effective > > treatment than T4 in reducing depressive symptoms. Spectulating: perhaps > T4 > > to T3 conversion in the brain's astrocytes and tanycytes is impaired by > lack > > of D2 Diodinase production, among other possible problems in brain > thyroid > > hormone metabolism. > > > > In bipolar disorder, historically, T4 is much more effective than T3 in > > stabilizing mood. T4 may be used medicinally to reach " hyperthyroid " > levels > > - based on TSH measurements - in psychiatry to stabilize mood in bipolar > > disorder. Speculating: perhaps, in bipolar disorder, there is a gene > > mutation in one of the thyroid transport molecules which selectively > impairs > > T3 transport. > > > > If a person is having problems with a T3 treatment or Armour Thyroid > > Treatment (which is primarily a T3 treatment), then perhaps adding a T4 > > treatment would be useful. Some patients benefit from combinations of > > thyroid treatments (e.g. T3 + T4, Armour Thyroid + Levothyroxine) better > > than single treatments alone. > > __________________ > > Romeo B. no, MD, physician, psychiatrist > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Check out TiredThyroid.com, a new website that covers the most > > common > > > > > > topics discussed on the forums, with medical journal references > to > > > > convince > > > > > > your doctor that " you CAN believe what you read on the internet! " > > > > > > > > > > > > More info on the rT3 debate: http://tiredthyroid.com/rt3.html > > > > > > > > > > > > Why you shouldn't donate blood more than twice a year: > > > > > > http://tiredthyroid.com/mens-hormones.html > > > > > > > > > > > > Why you shouldn't trust a TSH to tell if you're hypothyroid: > > > > > > http://tiredthyroid.com/tsh.html > > > > > > > > > > > > Barb > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > -- > > > > > Mike > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 22, 2011 Report Share Posted February 22, 2011 Its another patient web site and can't be taken for 100% truth. Everyone chemistry is different and everyone needs different things. > > Check out TiredThyroid.com, a new website that covers the most common topics discussed on the forums, with medical journal references to convince your doctor that " you CAN believe what you read on the internet! " > > More info on the rT3 debate: http://tiredthyroid.com/rt3.html > > Why you shouldn't donate blood more than twice a year: > http://tiredthyroid.com/mens-hormones.html > > Why you shouldn't trust a TSH to tell if you're hypothyroid: > http://tiredthyroid.com/tsh.html > > > Barb > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 23, 2011 Report Share Posted February 23, 2011 Thanks Barb, Great wealth of info but I must say I don't agree with what was said about taking HC meds and the sides that were taked about. " The side effects are serious and include osteoporosis [2], glaucoma which can lead to blindness [3], weight gain and “buddha belly†[4], immune suppression that can lead to fungal infections and resistance to some cancer treatments [5,6], cardiovascular disease/ hypertension [7], diabetes [8], insomnia, and inability to tolerate any stress, which can lead to a fatal adrenal crisis [9]. " I don't think she read " Safe Uses of Cortisol " by by McK. Jeffries MD if one is taking a physiological dose of HC this dose not happen. http://www.stopthethyroidmadness.com/safe-uses/ Co-Moderator Phil > From: Barb <baba@...> > Subject: New Website with Medical Journal References for your Doctor > > Date: Tuesday, February 22, 2011, 9:15 PM > Check out TiredThyroid.com, a new > website that covers the most common topics discussed on the > forums, with medical journal references to convince your > doctor that " you CAN believe what you read on the > internet! " >  > More info on the rT3 debate: http://tiredthyroid.com/rt3.html > > Why you shouldn't donate blood more than twice a year: > http://tiredthyroid.com/mens-hormones.html > > Why you shouldn't trust a TSH to tell if you're > hypothyroid: > http://tiredthyroid.com/tsh.html > > > Barb > > > > > ------------------------------------ > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 23, 2011 Report Share Posted February 23, 2011 it helps if you say what the misinformation was I don't agree with what is said about taking HC meds. Co-Moderator Phil > > > > > > > Check out TiredThyroid.com, a new website that covers > the most common > > topics discussed on the forums, with medical journal > references to convince > > your doctor that " you CAN believe what you read on the > internet! " > > > > More info on the rT3 debate: http://tiredthyroid.com/rt3.html > > > > Why you shouldn't donate blood more than twice a > year: > > http://tiredthyroid.com/mens-hormones.html > > > > Why you shouldn't trust a TSH to tell if you're > hypothyroid: > > http://tiredthyroid.com/tsh.html > > > > Barb > > > >Â > > > > > > -- > Mike > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 23, 2011 Report Share Posted February 23, 2011 DH got pre-glaucoma, and so did others on Val's list, but we were put on full moderation after we mentioned it. Many have complained of the buddha belly/weight gain, DH got a squamous cell skin cancer, some on the list have developed diabetes and osteoporosis, and everyone complains of insomnia. Jeffries said it was safe to take 20 mg. Val's group recommends much higher doses to everyone. Barb > > > From: Barb <baba@...> > > Subject: New Website with Medical Journal References for your Doctor > > > > Date: Tuesday, February 22, 2011, 9:15 PM > > Check out TiredThyroid.com, a new > > website that covers the most common topics discussed on the > > forums, with medical journal references to convince your > > doctor that " you CAN believe what you read on the > > internet! " > >  > > More info on the rT3 debate: http://tiredthyroid.com/rt3.html > > > > Why you shouldn't donate blood more than twice a year: > > http://tiredthyroid.com/mens-hormones.html > > > > Why you shouldn't trust a TSH to tell if you're > > hypothyroid: > > http://tiredthyroid.com/tsh.html > > > > > > Barb > > > > > > > > > > ------------------------------------ > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 23, 2011 Report Share Posted February 23, 2011 I agree with Dr. M on this and as he says about it you can find a lot more he also says the brain needs T4 so it can make it's own T3 so the T3 you add to your body is not the same as the T3 the brain makes from T4. So adding T3 does very little for ones brain. ========================================== T4 levels are important since the brain does its own conversion of T4 to T3. The brain compartment can have different T4 and T3 levels than the rest of the body. The brain and body are in two different compartments, separated by the blood brain barrier. In Alzheimer's disease, brain thyroid levels are lower than the rest of the body. Co-Moderator Phil > From: Barb <baba@...> > Subject: Re: New Website with Medical Journal References for your Doctor > > Date: Tuesday, February 22, 2011, 10:23 PM > Yes, both T4 AND T3 cross the > barrier, but the brain works best with " fresh T3 " that it > just created from T4. There may be more to T4 in the > brain than just the conversion aspect, because some people > (me included), can attest to being brain-dead without T4 > (even with the T3 cranked up). Dr. no discusses > T4 in the brain here: > > Brain thyroid hormone levels and T3 to T4 ratios are going > to be determined at several levels. > > For example, the number and types and location of thyroid > transporters determines what amount of thyroid hormone gets > through. > > Variations in the genes for the thyroid transporter > molecules will determine how effective they are and how > selective they are for T3 or T4 transport - creating a > difference between Blood and Brain concentrations of Thyroid > hormones. > > Variations in Astrocyte and Tanycyte Diodinase D2 > production will determine T3 to T4 conversions in the brain, > which may be different from the blood. > > etc. > > --- > > From my point of view, given the differences that can arise > in blood versus brain levels of thyroid hormone and thyroid > hormone conversion, it is important to consider in some > patients to not only optimize T3 but to also optimize T4 > levels. > > This is important, for example, in mood disorders. Here, > the difference between T3 and T4 treatment becomes > apparent. > > In major depressive disorder, historically, T3 is a more > effective treatment than T4 in reducing depressive symptoms. > Spectulating: perhaps T4 to T3 conversion in the brain's > astrocytes and tanycytes is impaired by lack of D2 Diodinase > production, among other possible problems in brain thyroid > hormone metabolism. > > In bipolar disorder, historically, T4 is much more > effective than T3 in stabilizing mood. T4 may be used > medicinally to reach " hyperthyroid " levels - based on TSH > measurements - in psychiatry to stabilize mood in bipolar > disorder. Speculating: perhaps, in bipolar disorder, there > is a gene mutation in one of the thyroid transport molecules > which selectively impairs T3 transport. > > If a person is having problems with a T3 treatment or > Armour Thyroid Treatment (which is primarily a T3 > treatment), then perhaps adding a T4 treatment would be > useful. Some patients benefit from combinations of thyroid > treatments (e.g. T3 + T4, Armour Thyroid + Levothyroxine) > better than single treatments alone. > __________________ > Romeo B. no, MD, physician, psychiatrist > > > > > > > > > > > > > > > > > > > > > > Check out TiredThyroid.com, a new > website that covers the most common > > > > > topics discussed on the forums, with > medical journal references to > > > convince > > > > > your doctor that " you CAN believe what > you read on the internet! " > > > > > > > > > > More info on the rT3 debate: http://tiredthyroid.com/rt3.html > > > > > > > > > > Why you shouldn't donate blood more > than twice a year: > > > > > http://tiredthyroid.com/mens-hormones.html > > > > > > > > > > Why you shouldn't trust a TSH to tell > if you're hypothyroid: > > > > > http://tiredthyroid.com/tsh.html > > > > > > > > > > Barb > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > -- > > > > Mike > > > > > > > > > > > > [Non-text portions of this message have been > removed] > > > > > > > > > > > > > > > > > > > > > -- > > Mike > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 23, 2011 Report Share Posted February 23, 2011 Barb and Nigel I still don't get this FT3/RT3 if it's less then <20 one has a problm. My FT3/RT3 comes out to .0815789. One needs to put the units in the same units by divide by 10 to get pg/ml into ng/dl, and multiply by 10 to get ng/dl into pg/ml. ... So puting the units into pg/ml I get 11.78. Or putting the units into ng/dl I get 122.58. I never did see how they get this ratio. Or my mind is gone. TSH, 3RD Generation 2.61 range 0.40 – 4.50 mIU/L. T4 (Thyroxine), Total 7.5 range 4.5 – 12.0 mcg/dL. Free T4 Index (T7) 2.4 range 1.4 – 3.8. T4, Free 1.2 range 0.8 – 1.8 ng/dL. T3 Free 3.1 range 2.3 – 4.2 pg/mL. T3 Total 90 range 76 – 181 ng/dL. T3 Uptake 32 range 76 – 181 ng/dL. RT3 38 ng/dL Co-Moderator Phil > > > > > > > Yes, both T4 AND T3 cross the barrier, but the brain > works best with " fresh > > T3 " that it just created from T4. There may be more to > T4 in the brain than > > just the conversion aspect, because some people (me > included), can attest to > > being brain-dead without T4 (even with the T3 cranked > up). Dr. no > > discusses T4 in the brain here: > > > > Brain thyroid hormone levels and T3 to T4 ratios are > going to be determined > > at several levels. > > > > For example, the number and types and location of > thyroid transporters > > determines what amount of thyroid hormone gets > through. > > > > Variations in the genes for the thyroid transporter > molecules will > > determine how effective they are and how selective > they are for T3 or T4 > > transport - creating a difference between Blood and > Brain concentrations of > > Thyroid hormones. > > > > Variations in Astrocyte and Tanycyte Diodinase D2 > production will determine > > T3 to T4 conversions in the brain, which may be > different from the blood. > > > > etc. > > > > --- > > > > From my point of view, given the differences that can > arise in blood versus > > brain levels of thyroid hormone and thyroid hormone > conversion, it is > > important to consider in some patients to not only > optimize T3 but to also > > optimize T4 levels. > > > > This is important, for example, in mood disorders. > Here, the difference > > between T3 and T4 treatment becomes apparent. > > > > In major depressive disorder, historically, T3 is a > more effective > > treatment than T4 in reducing depressive symptoms. > Spectulating: perhaps T4 > > to T3 conversion in the brain's astrocytes and > tanycytes is impaired by lack > > of D2 Diodinase production, among other possible > problems in brain thyroid > > hormone metabolism. > > > > In bipolar disorder, historically, T4 is much more > effective than T3 in > > stabilizing mood. T4 may be used medicinally to reach > " hyperthyroid " levels > > - based on TSH measurements - in psychiatry to > stabilize mood in bipolar > > disorder. Speculating: perhaps, in bipolar disorder, > there is a gene > > mutation in one of the thyroid transport molecules > which selectively impairs > > T3 transport. > > > > If a person is having problems with a T3 treatment or > Armour Thyroid > > Treatment (which is primarily a T3 treatment), then > perhaps adding a T4 > > treatment would be useful. Some patients benefit from > combinations of > > thyroid treatments (e.g. T3 + T4, Armour Thyroid + > Levothyroxine) better > > than single treatments alone. > > __________________ > > Romeo B. no, MD, physician, psychiatrist > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Check out TiredThyroid.com, a new > website that covers the most > > common > > > > > > topics discussed on the forums, > with medical journal references to > > > > convince > > > > > > your doctor that " you CAN believe > what you read on the internet! " > > > > > > > > > > > > More info on the rT3 debate: http://tiredthyroid.com/rt3.html > > > > > > > > > > > > Why you shouldn't donate blood > more than twice a year: > > > > > > http://tiredthyroid.com/mens-hormones.html > > > > > > > > > > > > Why you shouldn't trust a TSH to > tell if you're hypothyroid: > > > > > > http://tiredthyroid.com/tsh.html > > > > > > > > > > > > Barb > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > -- > > > > > Mike > > > > > > > > > > > > > > > [Non-text portions of this message have > been removed] > > > > > > > > > > > > > > > > > > > > > > > > > > > > > -- > > > Mike > > > > > > > > > [Non-text portions of this message have been > removed] > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 23, 2011 Report Share Posted February 23, 2011 My sides are gone never came back but my heals on my feet are good now. My nails were soft and tore easy now they are every hard and don't break hard to cut. Co-Moderator Phil > From: Barb <baba@...> > Subject: Re: New Website with Medical Journal References for your Doctor > > Date: Tuesday, February 22, 2011, 11:57 PM > Thanks Nigel. So did your > eyebrows come back when you added T4? I still can't figure > mine out. Hole in the middle. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Check out TiredThyroid.com, a > new website that covers the most > > > common > > > > > > > topics discussed on the > forums, with medical journal references to > > > > > convince > > > > > > > your doctor that " you CAN > believe what you read on the internet! " > > > > > > > > > > > > > > More info on the rT3 debate: > http://tiredthyroid.com/rt3.html > > > > > > > > > > > > > > Why you shouldn't donate > blood more than twice a year: > > > > > > > http://tiredthyroid.com/mens-hormones.html > > > > > > > > > > > > > > Why you shouldn't trust a TSH > to tell if you're hypothyroid: > > > > > > > http://tiredthyroid.com/tsh.html > > > > > > > > > > > > > > Barb > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > -- > > > > > > Mike > > > > > > > > > > > > > > > > > > [Non-text portions of this message > have been removed] > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > -- > > > > Mike > > > > > > > > > > > > [Non-text portions of this message have been > removed] > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 23, 2011 Report Share Posted February 23, 2011 You need to link us to the Dr. Lowes your talking about there I think 3 of them out there some of what I read a there sites is way out there. Co-Moderator Phil > > > > > > > > > > > Yes, both T4 AND T3 cross the barrier, but the > brain works best with > > " fresh > > > T3 " that it just created from T4. There may be > more to T4 in the brain > > than > > > just the conversion aspect, because some people > (me included), can attest > > to > > > being brain-dead without T4 (even with the T3 > cranked up). Dr. no > > > discusses T4 in the brain here: > > > > > > Brain thyroid hormone levels and T3 to T4 ratios > are going to be > > determined > > > at several levels. > > > > > > For example, the number and types and location of > thyroid transporters > > > determines what amount of thyroid hormone gets > through. > > > > > > Variations in the genes for the thyroid > transporter molecules will > > > determine how effective they are and how > selective they are for T3 or T4 > > > transport - creating a difference between Blood > and Brain concentrations > > of > > > Thyroid hormones. > > > > > > Variations in Astrocyte and Tanycyte Diodinase D2 > production will > > determine > > > T3 to T4 conversions in the brain, which may be > different from the blood. > > > > > > etc. > > > > > > --- > > > > > > From my point of view, given the differences that > can arise in blood > > versus > > > brain levels of thyroid hormone and thyroid > hormone conversion, it is > > > important to consider in some patients to not > only optimize T3 but to > > also > > > optimize T4 levels. > > > > > > This is important, for example, in mood > disorders. Here, the difference > > > between T3 and T4 treatment becomes apparent. > > > > > > In major depressive disorder, historically, T3 is > a more effective > > > treatment than T4 in reducing depressive > symptoms. Spectulating: perhaps > > T4 > > > to T3 conversion in the brain's astrocytes and > tanycytes is impaired by > > lack > > > of D2 Diodinase production, among other possible > problems in brain > > thyroid > > > hormone metabolism. > > > > > > In bipolar disorder, historically, T4 is much > more effective than T3 in > > > stabilizing mood. T4 may be used medicinally to > reach " hyperthyroid " > > levels > > > - based on TSH measurements - in psychiatry to > stabilize mood in bipolar > > > disorder. Speculating: perhaps, in bipolar > disorder, there is a gene > > > mutation in one of the thyroid transport > molecules which selectively > > impairs > > > T3 transport. > > > > > > If a person is having problems with a T3 > treatment or Armour Thyroid > > > Treatment (which is primarily a T3 treatment), > then perhaps adding a T4 > > > treatment would be useful. Some patients benefit > from combinations of > > > thyroid treatments (e.g. T3 + T4, Armour Thyroid > + Levothyroxine) better > > > than single treatments alone. > > > __________________ > > > Romeo B. no, MD, physician, psychiatrist > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Check out TiredThyroid.com, a > new website that covers the most > > > common > > > > > > > topics discussed on the > forums, with medical journal references > > to > > > > > convince > > > > > > > your doctor that " you CAN > believe what you read on the internet! " > > > > > > > > > > > > > > More info on the rT3 debate: > http://tiredthyroid.com/rt3.html > > > > > > > > > > > > > > Why you shouldn't donate > blood more than twice a year: > > > > > > > http://tiredthyroid.com/mens-hormones.html > > > > > > > > > > > > > > Why you shouldn't trust a TSH > to tell if you're hypothyroid: > > > > > > > http://tiredthyroid.com/tsh.html > > > > > > > > > > > > > > Barb > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > -- > > > > > > Mike > > > > > > > > > > > > > > > > > > [Non-text portions of this message > have been removed] > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > -- > > > > Mike > > > > > > > > > > > > [Non-text portions of this message have been > removed] > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 23, 2011 Report Share Posted February 23, 2011 Your ratio is 8.1. You know it's probably not .8 or 81. 8.1?!! You'd better go on T3 only treatment! jk Actually I see you low on both T3 and T4. Barb > > > > > > > > > > > > > > > > > > > > > > > > > > > Check out TiredThyroid.com, a new > > website that covers the most > > > common > > > > > > > topics discussed on the forums, > > with medical journal references to > > > > > convince > > > > > > > your doctor that " you CAN believe > > what you read on the internet! " > > > > > > > > > > > > > > More info on the rT3 debate: http://tiredthyroid.com/rt3.html > > > > > > > > > > > > > > Why you shouldn't donate blood > > more than twice a year: > > > > > > > http://tiredthyroid.com/mens-hormones.html > > > > > > > > > > > > > > Why you shouldn't trust a TSH to > > tell if you're hypothyroid: > > > > > > > http://tiredthyroid.com/tsh.html > > > > > > > > > > > > > > Barb > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > -- > > > > > > Mike > > > > > > > > > > > > > > > > > > [Non-text portions of this message have > > been removed] > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > -- > > > > Mike > > > > > > > > > > > > [Non-text portions of this message have been > > removed] > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 23, 2011 Report Share Posted February 23, 2011 I guess some one can blame the meds they are on for other problems they have. If I could prove my muscle damage was from taking Statin Drugs I would be rich. I have talk to ton's of people on HC meds never had a problem on them. And I have talked a to a lot of people that self med them selfs and have all kinds of problems. Before I treated my Secondary Adrenal Insufficiency I was sick all the time with upper restpatory infections,Sinusitis,Bronchitis,Pneumonia and treatment was not working well until I went on HC meds. Now I don't have them problems. The last yr. I suffered from the above it dam near killed me I had Bronchitis all winter and most of the summer doing antibiotics and other meds. I ended up in the hosp. with Pneumonia. When I got out I was in very bad shape until I went on HC meds. Co-Moderator Phil > From: Barb <baba@...> > Subject: Re: New Website with Medical Journal References for your Doctor > > Date: Wednesday, February 23, 2011, 11:06 AM > DH got pre-glaucoma, and so did > others on Val's list, but we were put on full moderation > after we mentioned it. Many have complained of the > buddha belly/weight gain, DH got a squamous cell skin > cancer, some on the list have developed diabetes and > osteoporosis, and everyone complains of insomnia. > Jeffries said it was safe to take 20 mg. Val's group > recommends much higher doses to everyone. > > Barb > > > > > > > From: Barb <baba@...> > > > Subject: New Website with Medical > Journal References for your Doctor > > > > > > Date: Tuesday, February 22, 2011, 9:15 PM > > > Check out TiredThyroid.com, a new > > > website that covers the most common topics > discussed on the > > > forums, with medical journal references to > convince your > > > doctor that " you CAN believe what you read on > the > > > internet! " > > >  > > > More info on the rT3 debate: http://tiredthyroid.com/rt3.html > > > > > > Why you shouldn't donate blood more than twice a > year: > > > http://tiredthyroid.com/mens-hormones.html > > > > > > Why you shouldn't trust a TSH to tell if you're > > > hypothyroid: > > > http://tiredthyroid.com/tsh.html > > > > > > > > > Barb > > > > > > > > > > > > > > > ------------------------------------ > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 23, 2011 Report Share Posted February 23, 2011 Still it's one of the better ones I have seen she did a dam good job here. Co-Moderator Phil > From: antanas_aradas <antanas_aradas@...> > Subject: Re: New Website with Medical Journal References for your Doctor > > Date: Wednesday, February 23, 2011, 1:53 AM > Its another patient web site and > can't be taken for 100% truth. > Everyone chemistry is different and everyone needs > different things. > > > > > > Check out TiredThyroid.com, a new website that covers > the most common topics discussed on the forums, with medical > journal references to convince your doctor that " you CAN > believe what you read on the internet! " > >Â Â Â > > More info on the rT3 debate: http://tiredthyroid.com/rt3.html > > > > Why you shouldn't donate blood more than twice a year: > > > http://tiredthyroid.com/mens-hormones.html > > > > Why you shouldn't trust a TSH to tell if you're > hypothyroid: > > http://tiredthyroid.com/tsh.html > > > > > > Barb > > > > > > > ------------------------------------ > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 23, 2011 Report Share Posted February 23, 2011 Nope I can't do more then 5 mcgs of T3 3x's per day when I did them labs I was on 2x's / day. My RT3 is due to heart surgery and Statin muscle damage causing me a lot of pain. Other then that I feel fine. So when you do the ratio you don't convert into the same units or it's conberting moving the dec. point over. If I do more T3 I go hyper. Co-Moderator Phil > From: Barb <baba@...> > Subject: Re: New Website with Medical Journal References for your Doctor > > Date: Wednesday, February 23, 2011, 11:33 AM > Your ratio is 8.1. You know > it's probably not .8 or 81. 8.1?!! You'd better go on > T3 only treatment! jk Actually I see you low on both > T3 and T4. > > Barb > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Check out > TiredThyroid.com, a new > > > website that covers the most > > > > common > > > > > > > > topics discussed on the > forums, > > > with medical journal references to > > > > > > convince > > > > > > > > your doctor that " you > CAN believe > > > what you read on the internet! " > > > > > > > > > > > > > > > > More info on the rT3 > debate: http://tiredthyroid.com/rt3.html > > > > > > > > > > > > > > > > Why you shouldn't donate > blood > > > more than twice a year: > > > > > > > > http://tiredthyroid.com/mens-hormones.html > > > > > > > > > > > > > > > > Why you shouldn't trust > a TSH to > > > tell if you're hypothyroid: > > > > > > > > http://tiredthyroid.com/tsh.html > > > > > > > > > > > > > > > > Barb > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > -- > > > > > > > Mike > > > > > > > > > > > > > > > > > > > > > [Non-text portions of this > message have > > > been removed] > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > -- > > > > > Mike > > > > > > > > > > > > > > > [Non-text portions of this message have > been > > > removed] > > > > > > > > > > > > > > > > > > > > > > > > > > [Non-text portions of this message have been > removed] > > > > > > > > > > > > ------------------------------------ > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 23, 2011 Report Share Posted February 23, 2011 Glaucoma is a side effect of HC use in about 8% of people called steroid responders. That means 92%, or most people following Val's instructions, won't develop that problem. But if you're in that 8%, wow, blindness? That's a real risk that people should be warned about, and aren't. Regular eye doctor appts are imperative if taking HC. > > > > > > > From: Barb <baba@> > > > > Subject: New Website with Medical > > Journal References for your Doctor > > > > > > > > Date: Tuesday, February 22, 2011, 9:15 PM > > > > Check out TiredThyroid.com, a new > > > > website that covers the most common topics > > discussed on the > > > > forums, with medical journal references to > > convince your > > > > doctor that " you CAN believe what you read on > > the > > > > internet! " > > > >  > > > > More info on the rT3 debate: http://tiredthyroid.com/rt3.html > > > > > > > > Why you shouldn't donate blood more than twice a > > year: > > > > http://tiredthyroid.com/mens-hormones.html > > > > > > > > Why you shouldn't trust a TSH to tell if you're > > > > hypothyroid: > > > > http://tiredthyroid.com/tsh.html > > > > > > > > > > > > Barb > > > > > > > > > > > > > > > > > > > > ------------------------------------ > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 23, 2011 Report Share Posted February 23, 2011 It's an interesting debate here but honestly, my brain is too tired today to even go there today. Barb - great job on the website. I'll definitely keep it in my resource bookmark folder for future reference. It looks like you are being treated by Dr. no - good for you. I am also being treated by him and he is a great doctor. The man is in the process of saving my life, literally. Phil - Sorry for being so lazy but you can google his name and it will take you to his website. He has a FAQ page that goes over all of the stuff I talked about. Mike On Wed, Feb 23, 2011 at 1:19 PM, babalo1234 <baba@...> wrote: > > > Glaucoma is a side effect of HC use in about 8% of people called steroid > responders. That means 92%, or most people following Val's instructions, > won't develop that problem. But if you're in that 8%, wow, blindness? That's > a real risk that people should be warned about, and aren't. Regular eye > doctor appts are imperative if taking HC. > > > > > > > > > > > > From: Barb <baba@> > > > > > Subject: New Website with Medical > > > Journal References for your Doctor > > > > > > > > > > Date: Tuesday, February 22, 2011, 9:15 PM > > > > > Check out TiredThyroid.com, a new > > > > > website that covers the most common topics > > > discussed on the > > > > > forums, with medical journal references to > > > convince your > > > > > doctor that " you CAN believe what you read on > > > the > > > > > internet! " > > > > > Â > > > > > More info on the rT3 debate: http://tiredthyroid.com/rt3.html > > > > > > > > > > Why you shouldn't donate blood more than twice a > > > year: > > > > > http://tiredthyroid.com/mens-hormones.html > > > > > > > > > > Why you shouldn't trust a TSH to tell if you're > > > > > hypothyroid: > > > > > http://tiredthyroid.com/tsh.html > > > > > > > > > > > > > > > Barb > > > > > > > > > > > > > > > > > > > > > > > > > ------------------------------------ > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 23, 2011 Report Share Posted February 23, 2011 I only know of Dr. no through his website, but am a huge fan. Finally, someone who really knows their stuff! Just curious, you're his patient and he's ok with T3-only treatment? Barb > > > > > > > > > > > From: Barb <baba@> > > > > > > Subject: New Website with Medical > > > > Journal References for your Doctor > > > > > > > > > > > > Date: Tuesday, February 22, 2011, 9:15 PM > > > > > > Check out TiredThyroid.com, a new > > > > > > website that covers the most common topics > > > > discussed on the > > > > > > forums, with medical journal references to > > > > convince your > > > > > > doctor that " you CAN believe what you read on > > > > the > > > > > > internet! " > > > > > > Â > > > > > > More info on the rT3 debate: http://tiredthyroid.com/rt3.html > > > > > > > > > > > > Why you shouldn't donate blood more than twice a > > > > year: > > > > > > http://tiredthyroid.com/mens-hormones.html > > > > > > > > > > > > Why you shouldn't trust a TSH to tell if you're > > > > > > hypothyroid: > > > > > > http://tiredthyroid.com/tsh.html > > > > > > > > > > > > > > > > > > Barb > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > ------------------------------------ > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 23, 2011 Report Share Posted February 23, 2011 Yes he is okay with me being on T3. He says that every patient is unique and requires unique treatments. He has some patients on T4 only, some on a combo and, as with me, some on T3 only. On Wed, Feb 23, 2011 at 8:45 PM, Barb <baba@...> wrote: > > > I only know of Dr. no through his website, but am a huge fan. Finally, > someone who really knows their stuff! Just curious, you're his patient and > he's ok with T3-only treatment? > > Barb > > > > > > > > > > > > > > > From: Barb <baba@> > > > > > > > Subject: New Website with Medical > > > > > Journal References for your Doctor > > > > > > > > > > > > > > Date: Tuesday, February 22, 2011, 9:15 PM > > > > > > > Check out TiredThyroid.com, a new > > > > > > > website that covers the most common topics > > > > > discussed on the > > > > > > > forums, with medical journal references to > > > > > convince your > > > > > > > doctor that " you CAN believe what you read on > > > > > the > > > > > > > internet! " > > > > > > > Â > > > > > > > More info on the rT3 debate: http://tiredthyroid.com/rt3.html > > > > > > > > > > > > > > Why you shouldn't donate blood more than twice a > > > > > year: > > > > > > > http://tiredthyroid.com/mens-hormones.html > > > > > > > > > > > > > > Why you shouldn't trust a TSH to tell if you're > > > > > > > hypothyroid: > > > > > > > http://tiredthyroid.com/tsh.html > > > > > > > > > > > > > > > > > > > > > Barb > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > ------------------------------------ > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 23, 2011 Report Share Posted February 23, 2011 That's what I like about him--he's open-minded. > > > > > > > > > > > > > > > From: Barb <baba@> > > > > > > > > Subject: New Website with Medical > > > > > > Journal References for your Doctor > > > > > > > > > > > > > > > > Date: Tuesday, February 22, 2011, 9:15 PM > > > > > > > > Check out TiredThyroid.com, a new > > > > > > > > website that covers the most common topics > > > > > > discussed on the > > > > > > > > forums, with medical journal references to > > > > > > convince your > > > > > > > > doctor that " you CAN believe what you read on > > > > > > the > > > > > > > > internet! " > > > > > > > > Â > > > > > > > > More info on the rT3 debate: http://tiredthyroid.com/rt3.html > > > > > > > > > > > > > > > > Why you shouldn't donate blood more than twice a > > > > > > year: > > > > > > > > http://tiredthyroid.com/mens-hormones.html > > > > > > > > > > > > > > > > Why you shouldn't trust a TSH to tell if you're > > > > > > > > hypothyroid: > > > > > > > > http://tiredthyroid.com/tsh.html > > > > > > > > > > > > > > > > > > > > > > > > Barb > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > ------------------------------------ > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 23, 2011 Report Share Posted February 23, 2011 And he is smart enough to know how to prescribe and monitor all three. Very rare these days... On Wed, Feb 23, 2011 at 9:20 PM, Barb <baba@...> wrote: > > > That's what I like about him--he's open-minded. > > > > > > > > > > > > > > > > > > > From: Barb <baba@> > > > > > > > > > Subject: New Website with Medical > > > > > > > Journal References for your Doctor > > > > > > > > > > > > > > > > > > Date: Tuesday, February 22, 2011, 9:15 PM > > > > > > > > > Check out TiredThyroid.com, a new > > > > > > > > > website that covers the most common topics > > > > > > > discussed on the > > > > > > > > > forums, with medical journal references to > > > > > > > convince your > > > > > > > > > doctor that " you CAN believe what you read on > > > > > > > the > > > > > > > > > internet! " > > > > > > > > > Â > > > > > > > > > More info on the rT3 debate: > http://tiredthyroid.com/rt3.html > > > > > > > > > > > > > > > > > > Why you shouldn't donate blood more than twice a > > > > > > > year: > > > > > > > > > http://tiredthyroid.com/mens-hormones.html > > > > > > > > > > > > > > > > > > Why you shouldn't trust a TSH to tell if you're > > > > > > > > > hypothyroid: > > > > > > > > > http://tiredthyroid.com/tsh.html > > > > > > > > > > > > > > > > > > > > > > > > > > > Barb > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > ------------------------------------ > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
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