Guest guest Posted March 11, 2010 Report Share Posted March 11, 2010 There was an interesting thread the MESO board about how men with low SHGB do not respond well to TRT. That is so me. My last SHGB was 12 (18-47). My biggest complaints are no libido and fair to poor erections. Even with a Total T at the top of the range and the same for free T, my desire just is non-existent. I try to keep my E2 in the 20-30 range but maybe it needs to be lower. SHGB prefers T to E2 as far as what it wants to bind to. Currently taking 0.25mg of arimidex 2 times a week and 90 mg of depo-T every 7 days. Total T is 600-1000 ng/dl. Any thoughts? http://forum.mesomorphosis.com/mens-health-forum/testosterone-replacement-therap\ y-men-134237140.html Arkansas Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 11, 2010 Report Share Posted March 11, 2010 Yes how is our sugar levels are they to high Dr. M says this can lower SHBG. If this is not your problem try taking .25 mgs every other day see is you get some wood it should happen in less then week if not stop it for a week see it wood happens going up. ==================================================== I respect what Phil is doing for himself. However, I generally want to maintain SHBG (sex-hormone binding globulin) since it prolongs the duration of action of testosterone. Most of the time, I find SHBG too low rather than too high. Testosterone, itself, will drive SHBG down. Estrogen will increase SHBG. Thus controlling estradiol will lower SHBG. Insulin also will drive SHBG down. Insulin has the strongest effect on SHBG, compared to any other factor. Low SHBG is a good sign that a person has insulin resistance or diabetes - with lowers testosterone production. Insulin resistance or diabetes greatly increases the risk for cardiovascular disease. __________________ - Romeo B. no, MD, physician, psychiatrist Any information provided on www.definitivemind.com is for informational purposes only, is not medical advice, does not create a doctor/patient relationship or liability, is not exhaustive, does not cover all conditions or their treatment, and will change as knowledge progresses. Always seek the advice of your physician or other qualified health provider before undertaking any diet, exercise, supplement, medical, or other health program. Co-Moderator Phil > From: Dan Meatheany <dmeatheany@...> > Subject: Low SHGB > > Date: Thursday, March 11, 2010, 3:14 PM > There was an interesting thread the > MESO board about how men with low SHGB do not respond well > to TRT. That is so me. My last SHGB was 12 (18-47). My > biggest complaints are no libido and fair to poor erections. > Even with a Total T at the top of the range and the same for > free T, my desire just is non-existent. I try to keep my E2 > in the 20-30 range but maybe it needs to be lower. SHGB > prefers T to E2 as far as what it wants to bind to. > Currently taking 0.25mg of arimidex 2 times a week and 90 mg > of depo-T every 7 days. Total T is 600-1000 ng/dl. Any > thoughts? > > http://forum.mesomorphosis.com/mens-health-forum/testosterone-replacement-therap\ y-men-134237140.html > > Arkansas > > > > > > > ------------------------------------ > > Quote Link to comment Share on other sites More sharing options...
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