Re: Latest Testo and E2 results

[Guest guest]

Before someone replies to what I wrote below, I want to add the rest of the

hormone results that I got today:

S-Testosterone 18.3 (8,0 - 35,0 nmol/l)

Free Testosterone Index 8.0 (3,0 – 14,7) NOTE: FTI = testosterone (nmol/l) x

10/SHBG (nmol/l) = result.

Estradiol 0.13 (0,06 - 0,14 nmol/l)

SHBG 23 (8 - 60 nmol/l)

S-Cortisol 665 (138 - 690 nmol/l)

FSH 1.6 (<12,0 IE/l)

LH 3.2 (<12,0 IE/l)

Progesterone 1.4 (< 3,0 nmol/l)

OH-progesterone 3.8 (1,8 - 10,4 nmol/l)

S-Aldosterone - In process

S-Dihydrotestosteron - In process

S-rT3 - In process

Comments? Should I/Do I need Arimidex based on these labs? Or any other changes?

Total T looks a bit lowish to be! Weird!?!?

From: Gibcast <gibcast@...>

Subject: Latest Testo and E2 results

Date: Friday, March 18, 2011, 1:09 AM

 

I just got these real quickly over the phone form my stressed out GP:

Estradiol: 0.13 (0,06 - 0,14 nmol/l)

Total Testosterone 18.3 (8,0 - 35,0 nmol/l)

(I am on 1 pump 10% compounded T-gel daily; 100 mg testosterone pr 1 gram gel in

each pump - I do NOT take Arimidex now!)

So it does look like E2 is a bit highish. Maybe E2 changes a lil up and down

(mostly up, never really down from the point where it is now: High in range!)

because of other factors like Testosterone Gel not getting evenly absorbed from

my shoulders, depending on how long I smear it/how hard, etc. from time to time

I apply it? And.. Maybe other hormones are going up and down controlling E2?

Maybe diary (it does in fact!!!) increase E2, depeing on how much diary I eat?

Total T is not impressive. Shouldn't it be high in range!??! This is the same

number I get when I am not taking TRT. And while I optimal on Tyroid between

1997 and 2007, I remember I got readings for Total T as high as 25 nmol/l. So...

What's up?

All I know is: My penis is not working like it should. I rarely feel desire. It

almost never gets hard " just like that " (except sometimes in the mornings) and I

have weak ejaculate, a lot less volume in the ejaculate and also orgasms that

don't feel so amazing anymore. So TRT is definitely optimal right now.

Would you guys do some Arimidex based on these labs?

Then we have my stomach issues which are still a big

MYSTERY............................... And could very well have caused a lot of

my hormone issues anyway!

[Guest guest]

Hi

How old are you? I am asking as that level of T 18.3 (8-35)

before T replacement looks ok to me.

My reading at age 53 was 4 (8-35) and that was low.

I am not sure why you are on testosterone replacement.

ok now your low sex drive

I would say that is from high E2 at the moment.

Try arimidex split pill in 4 and use every 4 days.

try Zink suplement pill in morning too

never heard of dairy products causing high E2

milk can maybe cause your stomach problems

your " a lot less volume in the ejaculate "

that is caused by replacing T with gels or injections

nothing you can do about it

i have same problem

You have to post your lab results here before any therapy was

started before we can comment

also any medications you are on

>

> I just got these real quickly over the phone form my stressed out GP:

>

> Estradiol: 0.13 (0,06 - 0,14 nmol/l)

> Total Testosterone 18.3 (8,0 - 35,0 nmol/l)

>

> (I am on 1 pump 10% compounded T-gel daily; 100 mg testosterone pr 1 gram gel

in each pump - I do NOT take Arimidex now!)

>

> So it does look like E2 is a bit highish. Maybe E2 changes a lil up and down

(mostly up, never really down from the point where it is now: High in range!)

because of other factors like Testosterone Gel not getting evenly absorbed from

my shoulders, depending on how long I smear it/how hard, etc. from time to time

I apply it? And.. Maybe other hormones are going up and down controlling E2?

Maybe diary (it does in fact!!!) increase E2, depeing on how much diary I eat?

>

> Total T is not impressive. Shouldn't it be high in range!??! This is the same

number I get when I am not taking TRT. And while I optimal on Tyroid between

1997 and 2007, I remember I got readings for Total T as high as 25 nmol/l. So...

What's up?

>

> All I know is: My penis is not working like it should. I rarely feel desire.

It almost never gets hard " just like that " (except sometimes in the mornings)

and I have weak ejaculate, a lot less volume in the ejaculate and also orgasms

that don't feel so amazing anymore. So TRT is definitely optimal right now.

>

> Would you guys do some Arimidex based on these labs?

>

> Then we have my stomach issues which are still a big

MYSTERY............................... And could very well have caused a lot of

my hormone issues anyway!

>

>

>

>

>

>

>

>

[Guest guest]

I am 32, and I was 21 when I came to my dr, Dr. Hertoghe in Brussels, Belgium. I

live in Norway. My Total T was 10 when I was overweight in my teens, not taking

any hormones at all. I was 320 lbs heavy and clearly Hypothyroid, but blood

samples told the endos I was within range. I finally got treated at age 18 at an

outcast of an endo who took my SYMTOMS seriously, not just staring blindly at

blood values. T4-treatment made me drop more than 100 lbs in less than a year,

and my Total T went up to 15-25. But never more than 25 while on optimal

Thyroid. I DID FEEL AMAZING in this period: 1997-2007. I had the best sexlife

possible, erections were never an issue, ejaculate was great, and volume was

huge! In the past 3 years however, I have been put off Thyroid by the first

public endos who once (in 1997) told me I was healthy despite my Hypo-symptoms

and massive overweight, condition worsened, and I have not live a life at all in

the past 3 years. I was put

on TRT, DHEA, ERFA THYROID and HC 1 year ago by Dr. Hertoghe, the worlds

premiere hormone doctor. I have lost almost 40 lbs in this time, and been eating

lowcarb, glutenfree diets. The S-Testosterone (Total Testosterone) value you see

here at 18, is while on TRT, 1 pump daily, that's 1 gram gel with 100 mg

Testosterone in it. I don't know why this value is not higher. Anyway. I was put

on TRT because my Total T was low range when I came to Dr. Hertoghe. However, I

was off the gel for 1 month last summer, and my Total T was at 15 when I was off

the gel. Not high enough, but I think it would've been higher if I had been

optimal in Thyroid. I am not optimal in Thyroid now, but Hertoghe doesn't

believe in treating ONE hormone optimal; He likes to treat ALL hormones and

balance them! I hate my sexlife now. It's non-existent. I feel little to no

desire. I can get a GREAT erection if I try, but I have to try! I don't get them

naturally anymore. I hate

it!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!! I know if I quit TRT, I

will get a normal working penis agian with better ejaculate volume! What's weird

was that when I tried 0.25 mg Arimidex one day, then another dose 2 days later,

I got better erections, I was more horny, and I had better ejaculate! WEIRD huh?

So I don't know what to do now... I also have a stomach issue that no-one has

found out what is in the last 3 1/2 years. Note: My stomach issue (loose/pale

stools) started 1/2 year before my whole body crashed. Maybe the STOMACH is the

ROOT of all evil in me. Whatever's wrong with it. I did visit Russia 3 times and

got issues with the stomach while being over there. So maybe some commie

bacteria, who knows.

From: Leon Eksteen <zorroceasar@...>

Subject: Re: Latest Testo and E2 results

Date: Friday, March 18, 2011, 2:29 PM

 

Hi

How old are you? I am asking as that level of T 18.3 (8-35)

before T replacement looks ok to me.

My reading at age 53 was 4 (8-35) and that was low.

I am not sure why you are on testosterone replacement.

ok now your low sex drive

I would say that is from high E2 at the moment.

Try arimidex split pill in 4 and use every 4 days.

try Zink suplement pill in morning too

never heard of dairy products causing high E2

milk can maybe cause your stomach problems

your " a lot less volume in the ejaculate "

that is caused by replacing T with gels or injections

nothing you can do about it

i have same problem

You have to post your lab results here before any therapy was

started before we can comment

also any medications you are on

>

> I just got these real quickly over the phone form my stressed out GP:

>

> Estradiol: 0.13 (0,06 - 0,14 nmol/l)

> Total Testosterone 18.3 (8,0 - 35,0 nmol/l)

>

> (I am on 1 pump 10% compounded T-gel daily; 100 mg testosterone pr 1 gram gel

in each pump - I do NOT take Arimidex now!)

>

> So it does look like E2 is a bit highish. Maybe E2 changes a lil up and down

(mostly up, never really down from the point where it is now: High in range!)

because of other factors like Testosterone Gel not getting evenly absorbed from

my shoulders, depending on how long I smear it/how hard, etc. from time to time

I apply it? And.. Maybe other hormones are going up and down controlling E2?

Maybe diary (it does in fact!!!) increase E2, depeing on how much diary I eat?

>

> Total T is not impressive. Shouldn't it be high in range!??! This is the same

number I get when I am not taking TRT. And while I optimal on Tyroid between

1997 and 2007, I remember I got readings for Total T as high as 25 nmol/l. So...

What's up?

>

> All I know is: My penis is not working like it should. I rarely feel desire.

It almost never gets hard " just like that " (except sometimes in the mornings)

and I have weak ejaculate, a lot less volume in the ejaculate and also orgasms

that don't feel so amazing anymore. So TRT is definitely optimal right now.

>

> Would you guys do some Arimidex based on these labs?

>

> Then we have my stomach issues which are still a big

MYSTERY............................... And could very well have caused a lot of

my hormone issues anyway!

>

>

>

>

>

>

>

>

[Guest guest]

Tom your levels are double what they should be .7 would be normal for you if my

units are right. Here in the USA the sweet spot is 20 pg/ml or 74 pmol/L.

If I were you suffering from this high E2 I would do the Arimidex. You got sick

around the time you took it last so this time try only taking one dose to see

how your stomach feels don't take it every other day or what your Dr. told you

to do just once to see how you feel if you get sick on it then you know. And

doing this low dose once you will not feel bad long.

Co-Moderator

Phil

> From: Gibcast <gibcast@...>

> Subject: Latest Testo and E2 results

>

> Date: Thursday, March 17, 2011, 8:09 PM

> I just got these real quickly over

> the phone form my stressed out GP:

>

> Estradiol: 0.13 (0,06 - 0,14 nmol/l)

> Total Testosterone 18.3 (8,0 - 35,0 nmol/l)

>

> (I am on 1 pump 10% compounded T-gel daily; 100 mg

> testosterone pr 1 gram gel in each pump - I do NOT take

> Arimidex now!)

>

> So it does look like E2 is a bit highish. Maybe E2 changes

> a lil up and down (mostly up, never really down from the

> point where it is now: High in range!) because of other

> factors like Testosterone Gel not getting evenly absorbed

> from my shoulders, depending on how long I smear it/how

> hard, etc. from time to time I apply it? And.. Maybe other

> hormones are going up and down controlling E2? Maybe diary

> (it does in fact!!!) increase E2, depeing on how much diary

> I eat?

>

> Total T is not impressive. Shouldn't it be high in

> range!??! This is the same number I get when I am not taking

> TRT. And while I optimal on Tyroid between 1997 and 2007, I

> remember I got readings for Total T as high as 25 nmol/l.

> So... What's up?

>

> All I know is: My penis is not working like it should. I

> rarely feel desire. It almost never gets hard " just like

> that " (except sometimes in the mornings) and I have weak

> ejaculate, a lot less volume in the ejaculate and also

> orgasms that don't feel so amazing anymore. So TRT is

> definitely optimal right now.

>

> Would you guys do some Arimidex based on these labs?

>

> Then we have my stomach issues which are still a big

> MYSTERY............................... And could very well

> have caused a lot of my hormone issues anyway!

>

>

>

>

>

>      

>

>

[Guest guest]

Tom,

It's hard to get good levels with high E2 levels.

Co-Moderator

Phil

>

> From: Gibcast <gibcast@...>

> Subject: Latest Testo and E2 results

>

> Date: Friday, March 18, 2011, 1:09 AM

>

>

>

>

>

>

>

>  

>

>

>

>  

>

>

>    

>      

>      

>       I just got these real quickly over the

> phone form my stressed out GP:

>

>

>

> Estradiol: 0.13 (0,06 - 0,14 nmol/l)

>

> Total Testosterone 18.3 (8,0 - 35,0 nmol/l)

>

>

>

> (I am on 1 pump 10% compounded T-gel daily; 100 mg

> testosterone pr 1 gram gel in each pump - I do NOT take

> Arimidex now!)

>

>

>

> So it does look like E2 is a bit highish. Maybe E2 changes

> a lil up and down (mostly up, never really down from the

> point where it is now: High in range!) because of other

> factors like Testosterone Gel not getting evenly absorbed

> from my shoulders, depending on how long I smear it/how

> hard, etc. from time to time I apply it? And.. Maybe other

> hormones are going up and down controlling E2? Maybe diary

> (it does in fact!!!) increase E2, depeing on how much diary

> I eat?

>

>

>

> Total T is not impressive. Shouldn't it be high in

> range!??! This is the same number I get when I am not taking

> TRT. And while I optimal on Tyroid between 1997 and 2007, I

> remember I got readings for Total T as high as 25 nmol/l.

> So... What's up?

>

>

>

> All I know is: My penis is not working like it should. I

> rarely feel desire. It almost never gets hard " just like

> that " (except sometimes in the mornings) and I have weak

> ejaculate, a lot less volume in the ejaculate and also

> orgasms that don't feel so amazing anymore. So TRT is

> definitely optimal right now.

>

>

>

> Would you guys do some Arimidex based on these labs?

>

>

>

> Then we have my stomach issues which are still a big

> MYSTERY............................... And could very well

> have caused a lot of my hormone issues anyway!

>

>

>

>

>

>

>

>

[Guest guest]

Really, Phil? So Testosterone does NOT increase well when E2 is high? I do feel

different when I am on TRT. When I am TRT my E2 is higher. I don't feel well

with higher E2. So I guess high E2 is one of the culprits of the Total of All I

feel like right now. Plus the stomach, which has been bad since 2007.

Hopefully I will force myself to do the Coloscopy next week.

>

> From: Gibcast <gibcast@...>

> Subject: Latest Testo and E2 results

>

> Date: Friday, March 18, 2011, 1:09 AM

>

>

>

>

>

>

>

>  

>

>

>

>  

>

>

>    

>      

>      

>       I just got these real quickly over the

> phone form my stressed out GP:

>

>

>

> Estradiol: 0.13 (0,06 - 0,14 nmol/l)

>

> Total Testosterone 18.3 (8,0 - 35,0 nmol/l)

>

>

>

> (I am on 1 pump 10% compounded T-gel daily; 100 mg

> testosterone pr 1 gram gel in each pump - I do NOT take

> Arimidex now!)

>

>

>

> So it does look like E2 is a bit highish. Maybe E2 changes

> a lil up and down (mostly up, never really down from the

> point where it is now: High in range!) because of other

> factors like Testosterone Gel not getting evenly absorbed

> from my shoulders, depending on how long I smear it/how

> hard, etc. from time to time I apply it? And.. Maybe other

> hormones are going up and down controlling E2? Maybe diary

> (it does in fact!!!) increase E2, depeing on how much diary

> I eat?

>

>

>

> Total T is not impressive. Shouldn't it be high in

> range!??! This is the same number I get when I am not taking

> TRT. And while I optimal on Tyroid between 1997 and 2007, I

> remember I got readings for Total T as high as 25 nmol/l.

> So... What's up?

>

>

>

> All I know is: My penis is not working like it should. I

> rarely feel desire. It almost never gets hard " just like

> that " (except sometimes in the mornings) and I have weak

> ejaculate, a lot less volume in the ejaculate and also

> orgasms that don't feel so amazing anymore. So TRT is

> definitely optimal right now.

>

>

>

> Would you guys do some Arimidex based on these labs?

>

>

>

> Then we have my stomach issues which are still a big

> MYSTERY............................... And could very well

> have caused a lot of my hormone issues anyway!

>

>

>

>

>

>

>

>

[Guest guest]

Here is a link from T Nation about how T works in your body read this over a few

times you will see what I am talking about.

===================================================

The Big T

How your lifestyle influences

your Testosterone levels — Part 1

by M. Berardi

Like it or not (and I'm sure T-mag readers really like it), Testosterone is the

hormone of the decade. The granddaddy of the male hormones has gotten more media

attention over the last few years than any other hormone around. Heck, I even

heard a rumor that some crazy bodybuilding media guys were thinking of naming a

magazine after it. Can you imagine that?

While Testosterone (the hormone, of course) has been the target of much bad

press, I think that if you asked this big dog of hormones what he thought of all

of this, he would bark out something to the effect of " What of it? I must be

doing something right if they keep talking about me! Now can't you see I'm

trying to work this shaved little poodle over here? "

Although the popular media has made Testosterone out to be a destructive bad

guy, researchers have been slowly but surely embracing its use. Clinical trials

have been conducted in diverse groups of individuals from HIV wasting patients

and burn victims to people with compromised immunity, along with older men whose

" Testosterone " hasn't been up in years. There have even been a number of recent

trials investigating the use of Testosterone in healthy weight trained men. So

where do I sign up?

The results of these investigations have shown that Testosterone is not the

demon the medical community once thought it to be and that it actually can be of

great benefit to certain individuals and, in certain patients, possesses very

few risks.

I'm pretty positive though, that the use of Testosterone will never be condoned

for use in healthy weight trained males. To this end, us law abiding citizens

have to do the best we can with what we've got to work with. So let's talk about

how our own body provides us with the big T and what we can do, both naturally

and with dietary supplements, to maximize our T levels.

When most people think of steroids, they tend only to think of Testosterone.

This, my friends, is yet another fact which tends to make me believe that T is

the hormone of the decade. Testosterone, however, is only one member of the

steroid family. Some of the other steroids in this family include cholesterol,

progesterone, the estrogens, cortisol, and aldosterone.

Although these molecules are part of the same family and have strikingly similar

structures, their functions differ like night and day. This is important to

recognize because although the steroids tend to act very differently, they are

subject to similar rules with respect to biochemistry and metabolism.

For a simplified view of steroid metabolism in the body, you can assume that all

steroid hormones begin with cholesterol. From cholesterol, steroid metabolites

are formed in various tissues of the body. For example, enzymes in the adrenal

glands are responsible for converting cholesterol into cortisol, while enzymes

in the gonads are responsible for converting cholesterol to Testosterone.

With this simplified view, it's easy to make the mistake of thinking that by

simply providing the body with more cholesterol (make that two large fries,

please), we can make more Testosterone. This is a mistake because the body has

regulatory mechanisms that control hormone production. These regulatory

mechanisms, not your bedtime prayers to the iron gods, are what determine which

steroid metabolites will ultimately be formed.

So the next important questions are, what magic does it take to make

Testosterone out of cholesterol (now don't get too excited, you can't do this in

your bath tub), what regulates this conversion, and ultimately, what regulates

Testosterone production? In order to get the gonads to produce T, the body has a

chain of command that must be dealt with just like any smooth running business.

In business, the action plan comes down from the CEO to upper management, the

plan is solidified and delegated to the production team, and the production team

gets the job done. Well, in the body, a portion of the brain called the

hypothalamus is the CEO, the pituitary gland is the upper management, and the

testes are the production team members.

As in business, the buck stops with the CEO/hypothalamus, which is known as a

" pulse generator, " because during the day it sends out pulses of hormones that

are designed to stimulate other organs. With respect to T, the hypothalamus

sends out numerous daily pulses of GNRH (gonadotropin releasing hormone) through

the blood stream. These pulses are designed to stimulate the pituitary gland to

get to work.

The pituitary gland then senses the pulses of GNRH and sends out a work order of

its own, consisting of LH (leutinizing hormone) pulses. The LH message travels

down to the leydig cells of the testis to stimulate the enzymatic conversion of

cholesterol to Testosterone.

Cholesterol conversion to T is no easy process and I'm not going to go into all

of the details (partly because no one really knows them all). One fact that you

should understand, though, is that there's a high level of complexity to this

pathway and that there are many enzymes and intermediates that cholesterol has

to encounter before forming T.

Some of these intermediates include pregnenolone, DHEA, androstenedione, and

other well-known androgens. So, although the hypothalamus might be functioning

well, the pituitary might be doing the right thing, and the testis are getting

the " ball " in motion, ultimately the enzymes in the leydig cells determine

whether you're pumping out loads of muscle building T or simply forming other

intermediates at the expense of the top dog.

As a result of the process I mentioned above, T levels fluctuate wildly. If you

were to measure your Testosterone levels throughout the day, you'd likely be

amazed. One minute you have the hormonal profile of a hyper-muscular bull ready

to " fertilize " an entire herd of cattle? and the next minute your blood profile

is that of a fully menstruating Martha intent on color coordinating your

powder room.

These odd fluctuations occur as a result of the pulsatile nature of hormone

secretion. Again, this begins with the hypothalamic pulse generator's release of

GNRH. Incidentally, researchers now believe that it is this physiologic

pulsatility of Testosterone that makes it anabolic. So if you can mimic this

pattern of hormone release, you can stimulate muscle growth.

With this hormonal cascade in mind, it's important to realize that each step in

the pathway has a regulation point designed to either stimulate or inhibit pulse

release. In this respect, the body is a bit of a control freak as it tends to

like many control points rather than just one.

In this particular case there are three main control points; the hypothalamus,

the pituitary, and the testis. With this type of control, the body can maintain

the Testosterone homeostasis (a sort of hormonal status quo) and prevent us from

any abnormal changes in muscle development and strength. For example, if our

Testosterone levels go way up, the body senses this and the hypothalamus and the

pituitary produce less GNRH and LH in order to slow down T production. This, of

course, is the famous negative feedback. Damn that homeostasis!

Now that I'm certain you're all experts in Testosterone production (and there

will be a test at the end — I'm serious!), I'd like to address one more

important issue that will come up later in the article with regard to

Testosterone in the body. When Testosterone is converted from cholesterol in the

leydig cells of the testis, it's released into the blood stream where it embarks

on an anabolic adventure.

However, when in the blood, 60% of the big T released from the boys down below

is bound up by a protein known as SHBG, or sex-hormone binding globulin. SHBG is

produced and released by the liver. The important point is that the Testosterone

bound to SHBG is biologically inactive and this is why there's an important

distinction between total T and bioavailable T.

Total T represents all the Testosterone in the blood, while bioavailable T

represents the non SHBG bound Testosterone. There are other proteins in the

blood that bind Testosterone, too, but their binding is rather weak, so this T

is bioavailable and these proteins can still enter the cells to produce and

effect all the things we're interested in.

As I said, bioavailable T represents the Testosterone that is not SHBG bound,

while free T represents the Testosterone that's not bound to any blood proteins

at all. It's tricky, I know, but I hope that it's now evident that although only

about 2% of the T in blood is technically considered free T, there is a larger

percentage of T (about 40% or so) that is bioavailable because it's only weakly

bound to non SHBG blood proteins.

I'm taking you through this complex path for good reason. When trying to

increase T levels in the body, one must attempt to not only increase total T.

More importantly, one must attempt to increase bioavailable T. If you increase

total T, but you increase SHBG to a larger extent, they you will actually have

less bioavailable T for muscle building purposes!

A great example of this is the use of both thyroid drugs and tamoxifen

(nolvadex). Both may increase total T levels in the body, but both also increase

SHBG to a large extent. Although you may get a bit of a T surge with each

(hurray!), the increase in SHBG may bind up any extra, and actually decrease

your bioavailable T (boo!).

Well, now that the class is up to speed with our physiology and endocrinology

(will someone please wake up Mr. Luoma! — he's always falling asleep during my

physiology lectures), we can dive, full force, into how lifestyle factors

including things like diet, training, recreational drugs, over the counter

medications, altitude, and how psychological mood states influence T levels.

There's an abundance of Testosterone literature out there and some of it is

applicable for us while some is not, but to a science geek like me who both

likes facts and likes being big and lean, it's all interesting nevertheless.

Oh wait, I almost forgot! Before we go on, I promised a test didn't I? Settle

down! Although there are no actual grades on this test, I hope that you take

away a few fundamental things from this article. If you can answer these

questions, you're ready to take on next week's article in which I'll review a

number of environmental and lifestyle factors that can influence your levels of

free T, total T, and bioavailable T.

Rest easy, next week's article ties in all that you learned this week and makes

some recommendations about how to up the T levels. And next week there won't be

a test!

Question #1 — True or False

Berardi is the most intelligent man on the face of the earth.

(I thought I'd start off with an easy one — And the answer of course is

" True " )

Question #2 — Short Answer

What are the three main organs/glands that regulate T production and what are

the big three hormones they release?

Question #3 — True or False

Testosterone is synthesized directly from cholesterol.

Question #4 — Short answer

What are the cells that actually produce T and where are they located?

Question #5 — Short answer

All the Testosterone in the body, bound and unbound is referred to as what?

Question #6 — Short answer

All the Testosterone that is not bound to SHBG is referred to as what?

Question #7 — Short answer

All the Testosterone not bound to any blood protein is known as what?

Question #8 — True or False

If you are interested in the anabolic effects of Testosterone, the optimal

situation is to increase total T levels and decrease SHBG.

This concludes Part 1 of " The Big T " . Next week, will conclude the article

with a review of both interesting and applicable Testosterone research.

M Berardi is a former national level competitive bodybuilder and an

exercise biochemist at the University of Western Ontario. He can be reached for

consultation at JMBMUSCLE@....

Co-Moderator

Phil

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> > From: Gibcast <gibcast@...>

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> > Subject: Latest Testo and E2 results

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> > Date: Friday, March 18, 2011, 1:09 AM

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> >       I just got these real quickly over the

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> > phone form my stressed out GP:

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> > Estradiol: 0.13 (0,06 - 0,14 nmol/l)

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> > Total Testosterone 18.3 (8,0 - 35,0 nmol/l)

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> > (I am on 1 pump 10% compounded T-gel daily; 100 mg

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> > testosterone pr 1 gram gel in each pump - I do NOT

> take

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> > Arimidex now!)

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> > So it does look like E2 is a bit highish. Maybe E2

> changes

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> > a lil up and down (mostly up, never really down from

> the

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> > point where it is now: High in range!) because of

> other

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> > factors like Testosterone Gel not getting evenly

> absorbed

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> > from my shoulders, depending on how long I smear

> it/how

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> > hard, etc. from time to time I apply it? And.. Maybe

> other

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> > hormones are going up and down controlling E2? Maybe

> diary

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> > (it does in fact!!!) increase E2, depeing on how much

> diary

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> > I eat?

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> > Total T is not impressive. Shouldn't it be high in

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> > range!??! This is the same number I get when I am not

> taking

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> > TRT. And while I optimal on Tyroid between 1997 and

> 2007, I

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> > remember I got readings for Total T as high as 25

> nmol/l.

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> > So... What's up?

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> > All I know is: My penis is not working like it should.

> I

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> > rarely feel desire. It almost never gets hard " just

> like

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> > that " (except sometimes in the mornings) and I have

> weak

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> > ejaculate, a lot less volume in the ejaculate and

> also

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> > orgasms that don't feel so amazing anymore. So TRT is

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> > definitely optimal right now.

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> > Would you guys do some Arimidex based on these labs?

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> > Then we have my stomach issues which are still a big

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> > MYSTERY............................... And could very

> well

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> > have caused a lot of my hormone issues anyway!

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