Guest guest Posted January 11, 2011 Report Share Posted January 11, 2011 > > I get the right effect from anastrozole. But I can't seem to get DIM to work for me. I just don't really respond to it. Like if my estrogen is high enough that I'm starting to get itchy all over I'll try DIM. I get relief for about a couple hours and then it wears off and all the high estrogen symptoms creep back. Or I can take one .25 mg anastrozole dose that fights hard and it's game over for estrogen for at least a day or two. > > I get the funky urine from DIM and respond for a short time to a dose. I think that means I'm absorbing it. But, for what it's worth, I'll note that I can NOT take Indolplex due to the soy in it (I'm extremely reactive to soy). I take Olympian Labs DIM which is just 100 mg DIM in a capsule. Again, the temporary response and dark urine would suggest at least to me I do absorb it. But I guess I'll go ahead and try DIM again specifically put in a spoonful of oil to see if that works better. > > So I'm trying to figure out what else in my body is whacked out for DIM not to really work. I keep reading occasional stuff talking about methylation cycle being broken in ones that don't use DIM well, but haven't been able to apply things to me. I have tested homocysteine when I was just on some methyl B12 sublinguals and it was down to about a 5, which I believe is on the low end. Methyl B12 shots or TMG don't seem to make DIM work better at all. > > Anyway, I just want to be able to fall back on DIM in case I'm without anastrozole in the future. Otherwise I'll just use anastrozole. > > Thanks for any input on this. > > -Nigel > when homocystein levels are under 5 then you have potential issues with detoxifcation of toxins and is increasing your chances of cardiovascular disease. http://www.metametrix.com/files/learning-center/articles/Hypohomocysteinemia.pdf With regular Dim you can use oil as transporter which works perfectly fine. Balacing out the liver and gut will also play into a huge factor into proper metabolisms of estrogens. If its the same nigel from the thyroid boards welcome. Are you still dealing with the same elevated shbg levels? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 11, 2011 Report Share Posted January 11, 2011 All I can say and I think we talked about this before is try the DIM with oil to get pasted your stomach. Hardasnails loves DIM I was doing Arimidex and DIM but it gave me a rash. You can try doing DIM everyday and 1 to 2 x's a week take ..25 mgs of Arimidex see how this work. Yes DIM makes your urine funky. Nigel once again Welcome to the forum. Co-Moderator Phil > From: nachohypo <nachonigel@...> > Subject: How do I get DIM to work for me? > > Date: Monday, January 10, 2011, 5:58 PM > I get the right effect from > anastrozole. But I can't seem to get DIM to work for me. I > just don't really respond to it. Like if my estrogen is high > enough that I'm starting to get itchy all over I'll try DIM. > I get relief for about a couple hours and then it wears off > and all the high estrogen symptoms creep back. Or I can take > one .25 mg anastrozole dose that fights hard and it's game > over for estrogen for at least a day or two. > > I get the funky urine from DIM and respond for a short time > to a dose. I think that means I'm absorbing it. But, for > what it's worth, I'll note that I can NOT take Indolplex due > to the soy in it (I'm extremely reactive to soy). I take > Olympian Labs DIM which is just 100 mg DIM in a capsule. > Again, the temporary response and dark urine would suggest > at least to me I do absorb it. But I guess I'll go ahead and > try DIM again specifically put in a spoonful of oil to see > if that works better. > > So I'm trying to figure out what else in my body is whacked > out for DIM not to really work. I keep reading occasional > stuff talking about methylation cycle being broken in ones > that don't use DIM well, but haven't been able to apply > things to me. I have tested homocysteine when I was just on > some methyl B12 sublinguals and it was down to about a 5, > which I believe is on the low end. Methyl B12 shots or TMG > don't seem to make DIM work better at all. > > Anyway, I just want to be able to fall back on DIM in case > I'm without anastrozole in the future. Otherwise I'll just > use anastrozole. > > Thanks for any input on this. > > -Nigel > > > > ------------------------------------ > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 11, 2011 Report Share Posted January 11, 2011 Sorry to hijack this post but what kind of oil do you recommend Phil? Thanks, Mike On Tue, Jan 11, 2011 at 9:42 AM, philip georgian <pmgamer18@...>wrote: > > > All I can say and I think we talked about this before is try the DIM with > oil to get pasted your stomach. Hardasnails loves DIM I was doing Arimidex > and DIM but it gave me a rash. You can try doing DIM everyday and 1 to 2 x's > a week take .25 mgs of Arimidex see how this work. Yes DIM makes your urine > funky. > > Nigel once again Welcome to the forum. > > Co-Moderator > Phil > > > > > From: nachohypo <nachonigel@... <nachonigel%40gmail.com>> > > Subject: How do I get DIM to work for me? > > < %40> > > Date: Monday, January 10, 2011, 5:58 PM > > I get the right effect from > > anastrozole. But I can't seem to get DIM to work for me. I > > just don't really respond to it. Like if my estrogen is high > > enough that I'm starting to get itchy all over I'll try DIM. > > I get relief for about a couple hours and then it wears off > > and all the high estrogen symptoms creep back. Or I can take > > one .25 mg anastrozole dose that fights hard and it's game > > over for estrogen for at least a day or two. > > > > I get the funky urine from DIM and respond for a short time > > to a dose. I think that means I'm absorbing it. But, for > > what it's worth, I'll note that I can NOT take Indolplex due > > to the soy in it (I'm extremely reactive to soy). I take > > Olympian Labs DIM which is just 100 mg DIM in a capsule. > > Again, the temporary response and dark urine would suggest > > at least to me I do absorb it. But I guess I'll go ahead and > > try DIM again specifically put in a spoonful of oil to see > > if that works better. > > > > So I'm trying to figure out what else in my body is whacked > > out for DIM not to really work. I keep reading occasional > > stuff talking about methylation cycle being broken in ones > > that don't use DIM well, but haven't been able to apply > > things to me. I have tested homocysteine when I was just on > > some methyl B12 sublinguals and it was down to about a 5, > > which I believe is on the low end. Methyl B12 shots or TMG > > don't seem to make DIM work better at all. > > > > Anyway, I just want to be able to fall back on DIM in case > > I'm without anastrozole in the future. Otherwise I'll just > > use anastrozole. > > > > Thanks for any input on this. > > > > -Nigel > > > > > > > > ------------------------------------ > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 11, 2011 Report Share Posted January 11, 2011 EVO (extravirgin olive oil) works the best. just a tsp is perfect. > > > > > From: nachohypo <nachonigel@... <nachonigel%40gmail.com>> > > > Subject: How do I get DIM to work for me? > > > < %40> > > > Date: Monday, January 10, 2011, 5:58 PM > > > I get the right effect from > > > anastrozole. But I can't seem to get DIM to work for me. I > > > just don't really respond to it. Like if my estrogen is high > > > enough that I'm starting to get itchy all over I'll try DIM. > > > I get relief for about a couple hours and then it wears off > > > and all the high estrogen symptoms creep back. Or I can take > > > one .25 mg anastrozole dose that fights hard and it's game > > > over for estrogen for at least a day or two. > > > > > > I get the funky urine from DIM and respond for a short time > > > to a dose. I think that means I'm absorbing it. But, for > > > what it's worth, I'll note that I can NOT take Indolplex due > > > to the soy in it (I'm extremely reactive to soy). I take > > > Olympian Labs DIM which is just 100 mg DIM in a capsule. > > > Again, the temporary response and dark urine would suggest > > > at least to me I do absorb it. But I guess I'll go ahead and > > > try DIM again specifically put in a spoonful of oil to see > > > if that works better. > > > > > > So I'm trying to figure out what else in my body is whacked > > > out for DIM not to really work. I keep reading occasional > > > stuff talking about methylation cycle being broken in ones > > > that don't use DIM well, but haven't been able to apply > > > things to me. I have tested homocysteine when I was just on > > > some methyl B12 sublinguals and it was down to about a 5, > > > which I believe is on the low end. Methyl B12 shots or TMG > > > don't seem to make DIM work better at all. > > > > > > Anyway, I just want to be able to fall back on DIM in case > > > I'm without anastrozole in the future. Otherwise I'll just > > > use anastrozole. > > > > > > Thanks for any input on this. > > > > > > -Nigel > > > > > > > > > > > > ------------------------------------ > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 11, 2011 Report Share Posted January 11, 2011 Olive or what ever you like. Co-Moderator Phil > > > > > From: nachohypo <nachonigel@... > <nachonigel%40gmail.com>> > > > Subject: How do I get DIM to work > for me? > > > > < %40> > > > Date: Monday, January 10, 2011, 5:58 PM > > > I get the right effect from > > > anastrozole. But I can't seem to get DIM to work > for me. I > > > just don't really respond to it. Like if my > estrogen is high > > > enough that I'm starting to get itchy all over > I'll try DIM. > > > I get relief for about a couple hours and then it > wears off > > > and all the high estrogen symptoms creep back. Or > I can take > > > one .25 mg anastrozole dose that fights hard and > it's game > > > over for estrogen for at least a day or two. > > > > > > I get the funky urine from DIM and respond for a > short time > > > to a dose. I think that means I'm absorbing it. > But, for > > > what it's worth, I'll note that I can NOT take > Indolplex due > > > to the soy in it (I'm extremely reactive to soy). > I take > > > Olympian Labs DIM which is just 100 mg DIM in a > capsule. > > > Again, the temporary response and dark urine > would suggest > > > at least to me I do absorb it. But I guess I'll > go ahead and > > > try DIM again specifically put in a spoonful of > oil to see > > > if that works better. > > > > > > So I'm trying to figure out what else in my body > is whacked > > > out for DIM not to really work. I keep reading > occasional > > > stuff talking about methylation cycle being > broken in ones > > > that don't use DIM well, but haven't been able to > apply > > > things to me. I have tested homocysteine when I > was just on > > > some methyl B12 sublinguals and it was down to > about a 5, > > > which I believe is on the low end. Methyl B12 > shots or TMG > > > don't seem to make DIM work better at all. > > > > > > Anyway, I just want to be able to fall back on > DIM in case > > > I'm without anastrozole in the future. Otherwise > I'll just > > > use anastrozole. > > > > > > Thanks for any input on this. > > > > > > -Nigel > > > > > > > > > > > > ------------------------------------ > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 12, 2011 Report Share Posted January 12, 2011 Thanks for the welcome. Ah, that link was good as it answered my question as to whether methionine can be realistically used to increase homocysteine. , have you found out if DIM raises or lowers homocysteine levels? I thought I'd read both ways. Any idea how it's changing the level? Yes, I've had the high SHBG levels. However, I understood some of that to be due to very high doses of thyroid hormones that I was taking to get relief from otherwise terrible hypothyroid symptoms. I've been able to reduce thyroid meds after I found out my ferritin was 41 last summer and have been working on getting iron stores up. So less thyroid has no doubt brought down SHBG level and I'll see where it is when I get my new tests results back. -Nigel > > > > > > when homocystein levels are under 5 then you have potential issues with detoxifcation of toxins and is increasing your chances of cardiovascular disease. > > http://www.metametrix.com/files/learning-center/articles/Hypohomocysteinemia.pdf > > With regular Dim you can use oil as transporter which works perfectly fine. Balacing out the liver and gut will also play into a huge factor into proper metabolisms of estrogens. If its the same nigel from the thyroid boards welcome. Are you still dealing with the same elevated shbg levels? > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 13, 2011 Report Share Posted January 13, 2011 Well, I think I can say that I've been able to finally introduce methionine without any drama now! I kept getting hyped up on it and couldn't sleep unless I took it in the morning. It was so bad that just the methionine from one ZMA pill could keep me up with an racing mind. I eventually connected that with symptoms I can get with too much copper (from copper-rich foods or from supplementing). I guess methionine can stir up copper, and I'm sure I have too much in my tissues. So I initially found out about molybdenum to take copper out and a couple milligrams here and there work very quickly to squash high copper symptoms. But that wasn't satisfactory as " low molybdenum " didn't fly as to WHY my copper levels have been high. It's not like sulphites in wine bother me anyway. Finally I found out that bile has to be flowing to get copper out of ya. Therefore, I've been taking taurine (shooting for a few grams a day) and a some glycine (in my chelated mag if no extra on its own) to produce more bile and I'm sure it's working as my copper excess symptoms are slowly subsiding. Although, I think adding methionine in requires some help still from the molybdenum supplements. But at least I could sleep the last couple nights even though I'd taken a couple grams of methionine. Till this point I thought people were CRAZY for suggesting methionine (by raising SAMe) could actually help with sleep. So yeah, you've got to look at your detox pathways 'cause that just might be the source of some problem with you. By the way, I got a clue that my bile production was low because my stool wasn't always that dark. Maybe I'll be able to get my homocysteine up finally. , do you think methionine will enable me to use DIM better and get more benefit from it? Yesterday I took 50 mg DIM that I put directly into a spoonful of cod liver oil and it didn't do anything and so I then took .25 mg anastrozole today to control excess estrogen. I'll still keep tinkering with the DIM to see if it works enough to lower my dependence on anastrozole. Oh, I responded to your question about my SHBG levels on this thread yesterday. I also asked if you recalled DIM raising or lowering homocysteine for any reason. Thanks if you can help on that last question. -Nigel > > > > > > when homocystein levels are under 5 then you have potential issues with detoxifcation of toxins and is increasing your chances of cardiovascular disease. > > http://www.metametrix.com/files/learning-center/articles/Hypohomocysteinemia.pdf > > With regular Dim you can use oil as transporter which works perfectly fine. Balacing out the liver and gut will also play into a huge factor into proper metabolisms of estrogens. If its the same nigel from the thyroid boards welcome. Are you still dealing with the same elevated shbg levels? > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 13, 2011 Report Share Posted January 13, 2011 You have to know what your are doing because if you get the methylation cycle spinning out of control it can make you worse. Sam-e detoxifies copper moly depletes copper and helps metabolize iron, depletes sulfur as well which slows down detoxfication of phase 1 and 2. One can use several things to lower ferritin in hemochromatosis or high ferritin levels beside blood letting. People that can not tolerate DIM have plug liver from slow methylation or phase 2 detoxifaction pathways. I have been preaching about bile and copper extraction for years LOL Get homocysteine up identify the heavy metal, or infection that you are dealing with. Specific mutation in mtfrr which is common for people with stress condition and anglo saxon, celtic background (also these people are rt3 prone due to genetic staravation from potatoe famine in the genees. SHBG is due to your thyroid meds or more so your inflammatory state I use proviron to lower it till I get other things balanced out I would work on lowering inflammation which can be done a few different ways. It really is case specific. > > > > > > > > > > > when homocystein levels are under 5 then you have potential issues with detoxifcation of toxins and is increasing your chances of cardiovascular disease. > > > > http://www.metametrix.com/files/learning-center/articles/Hypohomocysteinemia.pdf > > > > With regular Dim you can use oil as transporter which works perfectly fine. Balacing out the liver and gut will also play into a huge factor into proper metabolisms of estrogens. If its the same nigel from the thyroid boards welcome. Are you still dealing with the same elevated shbg levels? > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 13, 2011 Report Share Posted January 13, 2011 HAHAG then i get booted off thyroid boards because I would not tell them all my trade secrets. Actually I did but they did not pay attention to them unfortunately..Alot of people could be helped, but half of them have deeper issue which thyroid will not address. > > > > > > > > > > > when homocystein levels are under 5 then you have potential issues with detoxifcation of toxins and is increasing your chances of cardiovascular disease. > > > > http://www.metametrix.com/files/learning-center/articles/Hypohomocysteinemia.pdf > > > > With regular Dim you can use oil as transporter which works perfectly fine. Balacing out the liver and gut will also play into a huge factor into proper metabolisms of estrogens. If its the same nigel from the thyroid boards welcome. Are you still dealing with the same elevated shbg levels? > > > Quote Link to comment Share on other sites More sharing options...
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