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PSA up from 5 weeks ago

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Any change in your hormone levels until your body stabilizes on that change can

have an effect on PSA labs. Also have sex 48 hrs before the test can change it.

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Phil

> From: gviceman77@... <gviceman77@...>

> Subject: PSA up from 5 weeks ago

>

> Date: Sunday, February 28, 2010, 11:23 AM

> In 5 weeks

>

>

> My estradiol went down from 38 to 25.

>

> My estrogen went down from 189 to 128.

>

> MY PSA went up from 0.7 to 1.1 should I be 

> concerned?????

>

>

>

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On Sun, 28 Feb 2010 11:23:05 EST, you wrote:

>In 5 weeks

>

>

>My estradiol went down from 38 to 25.

>

>My estrogen went down from 189 to 128.

>

>MY PSA went up from 0.7 to 1.1 should I be concerned?????

That's almost with in test range variability. DOn't sweat it. 1.1 is

low.

http://www.labtestsonline.org/understanding/analytes/psa/test.html

PSA test results can be interpreted a number of different ways and

there may be differences in cutoff values between different

laboratories. The normal value for total PSA is considered to be less

than 4.0 ng/ml (nanograms per milliliter of blood). There are some

that feel that this level should be lowered to 2.5 ng/ml in order to

detect more cases of prostate cancer. Others argue that this would

exacerbate over-diagnosing and over-treating cancers that are not

clinically significant.

There is agreement that men with a total PSA level greater than 10.0

ng/ml are at an increased risk for prostate cancer (more than a 67%

chance, according to the ACS). Levels between 4.0 ng/ml and 10.0 ng/ml

may indicate prostate cancer (about a 25% chance, according to the

ACS), BPH, or prostatitis. These conditions are more common in the

elderly, as is a general increase in PSA levels. Concentrations of

total PSA between 4.0 ng/ml and 10.0 ng/ml are often referred to as

the “gray zone.” It is in this range that the free PSA is the most

useful. When men in the gray zone have decreased levels of free PSA,

they have a higher probability of prostate cancer; when they have

elevated levels of free PSA, the risk is diminished. The ratio of free

to total PSA can help the doctor decide whether or not a prostate

biopsy should be performed.

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