treatment for rt3.. read this link.

[Guest guest]

My testosterone levels are good, they are not an issue.

Sometimes you cannot " fix " the problems making RT3 go high when the problem is

prolonged stress (something you can't change, such as both parents having

prolonged cancer at the same time). High stress for prolonged periods can cause

RT3. The remedy in some cases is small doses of t3. Read this:

http://thyroid-rt3.com/howisit1.htm

In the meantime,

> > >

> > > I feel the men on T3 only meds for RT3 need to keep an

> > eye on there SHBG levels.

> > > http://tinyurl.com/36nxzdq

> > >

> > > Structure/function analyses of human sex

> > hormone-binding globulin: effects of zinc on steroid-binding

> > specificity

> > >

> > > In humans, sex hormone-binding globulin (SHBG) binds

> > and transports the biologically most important androgens and

> > estrogens in the blood, and regulates the access of these

> > steroids to their targets tissues. In addition to binding

> > sex steroids, SHBG has specific binding sites for divalent

> > cations including calcium and zinc. Zinc binding to a site

> > at the entrance of the steroid-binding pocket in human SHBG

> > has been shown to reduce its affinity for estrogens, while

> > having no impact on the binding of C19 steroids.

> > Crystallographic studies indicate that C18 and C19 steroids

> > are bound in opposite orientations within the SHBG

> > steroid-binding site, and we have obtained new information

> > that supports a molecular model explaining the mechanism by

> > which zinc alters the affinity of human SHBG for estrogens,

> > by studying directly the estradiol-binding properties SHBG

> > variants created by site-directed mutagenesis. In this

> > model, the coordination of a zinc ion by the side chains of

> > residues Asp65 and His136 eliminates a critical hydrogen

> > bond between Asp65 and the hydroxyl at C3 of estrogens, such

> > as estradiol and 2-methoxyestradiol, and causes disorder in

> > a polypeptide loop segment that covers the steroid-binding

> > site. The combination of these structural changes explains

> > the specific decrease in the affinity of human SHBG for C18

> > steroids in the presence of a zinc ion.

> > >

> >

> >

> >

> >

> > ------------------------------------

> >

> >

[Guest guest]

Clint that link is what got a lot of men in trouble with there SHBG levels and

the link most of the men that posted to me having problems were following this

link they ended up doing very high amounts of T3 only meds and lowering there

Free Testosterone levels.

The link is used by to meany people trying to lower there RT3 with out a Dr.

I feel and so dose Dr. this way is the best way.

http://www.custommedicine.com.au/health-articles/reverse-t3-dominance/

Co-Moderator

Phil

> From: Clint <atlfuzzy@...>

> Subject: treatment for rt3.. read this link.

>

> Date: Tuesday, October 26, 2010, 7:14 PM

> My testosterone levels are good, they

> are not an issue. 

> Sometimes you cannot " fix " the problems making RT3 go high

> when the problem is prolonged stress (something you can't

> change, such as both parents having prolonged cancer at the

> same time).  High stress for prolonged periods can

> cause RT3. The remedy in some cases is small doses of

> t3.  Read this:

>

>

> http://thyroid-rt3.com/howisit1.htm

>

>

>

>

>

> In the meantime,

>

>

> > > >

> > > > I feel the men on T3 only meds for RT3 need

> to keep an

> > > eye on there SHBG levels.

> > > > http://tinyurl.com/36nxzdq

> > > >

> > > > Structure/function analyses of human sex

> > > hormone-binding globulin: effects of zinc on

> steroid-binding

> > > specificity

> > > >

> > > > In humans, sex hormone-binding globulin

> (SHBG) binds

> > > and transports the biologically most important

> androgens and

> > > estrogens in the blood, and regulates the access

> of these

> > > steroids to their targets tissues. In addition to

> binding

> > > sex steroids, SHBG has specific binding sites for

> divalent

> > > cations including calcium and zinc. Zinc binding

> to a site

> > > at the entrance of the steroid-binding pocket in

> human SHBG

> > > has been shown to reduce its affinity for

> estrogens, while

> > > having no impact on the binding of C19 steroids.

> > > Crystallographic studies indicate that C18 and

> C19 steroids

> > > are bound in opposite orientations within the

> SHBG

> > > steroid-binding site, and we have obtained new

> information

> > > that supports a molecular model explaining the

> mechanism by

> > > which zinc alters the affinity of human SHBG for

> estrogens,

> > > by studying directly the estradiol-binding

> properties SHBG

> > > variants created by site-directed mutagenesis. In

> this

> > > model, the coordination of a zinc ion by the side

> chains of

> > > residues Asp65 and His136 eliminates a critical

> hydrogen

> > > bond between Asp65 and the hydroxyl at C3 of

> estrogens, such

> > > as estradiol and 2-methoxyestradiol, and causes

> disorder in

> > > a polypeptide loop segment that covers the

> steroid-binding

> > > site. The combination of these structural changes

> explains

> > > the specific decrease in the affinity of human

> SHBG for C18

> > > steroids in the presence of a zinc ion.

> > > >

> > >

> > >

> > >

> > >

> > > ------------------------------------

> > >

> > >