For My Guys Who Have Failed the HPTA-Restart

[Guest guest]

This was posted today by Dr. .

http://www.musclechatroom.com/forum/showthread.php?17612-For-My-Guys-Who-Have-Fa\

iled-the-HPTA-Restart

I have been thinking about this for a long time but waiting for this new drug to

come out called Androxal.

http://www.drugs.com/nda/androxal_100208.html

It would be so dam nice to only take a pill everyday to keep TT levels up.

=====================================================================

For My Guys Who Have Failed the HPTA-Restart

After a long Skype session a week ago with Dr. Shippen, I am rethinking the

HPTA-Restart.

A number of my patients have responded well to the clomiphene challenge. This

shows the HPTA is indeed intact. Yet when the SERM-class drug was withdrawn,

testosterone levels once again plummeted.

With the proven benefit of low dose clomiphene, at 12.5mgs (1/4 tablet for

convenience), or even less, I am now willing to maintain treatment, long term,

on same.

Those who did not enjoy the subjective benefit of the on-treatment testosterone

increase may have been sensitive to the estrogen agonism (mimic) half of the

clomiphene, or zuclomiphene. Others experienced a sharp increase in SHBG (again,

from the estrogen half of the drug), and so would have needed

incredible--unattainable--gains in T just to produce bioavailable androgen

levels sufficient to make them feel good.

Others simply have too much estrogen, either way.

For the latter example of therapy failure (by subjective report), we will add in

aromatase inhibition, to hinder the conversion of T to E. For those with

elevated SHBG, we can add in some oral Danazol to lower same. Once resultant

dosages are titrated, we should be able to include all in the same cap, to save

the patient money.

In my talks with Dr. Shippen, and well as Dr. Cabeca (Functional Medicine

physician extraordinaire) it is my belief residual toxic insult is the culprit

behind resumption of the hypogonadal state once clomiphene stimulation of the

HPTA is withdrawn.

Anyone who experienced good increases in T with clomiphene, without persistence

upon drug withdrawal, is now welcome to go on clomiphene long-term. Depending

upon the case, we may add in anastrozole and/or oral Danazol.

Keep in mind, " success " in previous restart attempt is defined merely as

sufficiently increased testosterone production. Whether you felt better at the

time or not is not reason for deferment. We can adjust estrogens and SHBG as

necessary to yield positive subjective response.

My guys will tell you I have always been happy to try a restart. For those with

failure to restart (meaning the system did not keep running once we stopped the

clomiphene) we can try the new protocol. It would be great if we could NOT use

TRT to restore health and happiness. Just call , tell her what you want,

and make an appointment. We'll get started right away.

Last edited by Dr. Crisler; 7 Hours Ago at 05:30 AM.

[Guest guest]

Glad you posted that Phil, as I expect to see the results of my Clomid challenge

this week.

I am printing this off to take with me!

>

> This was posted today by Dr. .

>

http://www.musclechatroom.com/forum/showthread.php?17612-For-My-Guys-Who-Have-Fa\

iled-the-HPTA-Restart

> I have been thinking about this for a long time but waiting for this new drug

to come out called Androxal.

> http://www.drugs.com/nda/androxal_100208.html

> It would be so dam nice to only take a pill everyday to keep TT levels up.

>

> =====================================================================

> For My Guys Who Have Failed the HPTA-Restart

> After a long Skype session a week ago with Dr. Shippen, I am rethinking the

HPTA-Restart.

>

> A number of my patients have responded well to the clomiphene challenge. This

shows the HPTA is indeed intact. Yet when the SERM-class drug was withdrawn,

testosterone levels once again plummeted.

>

> With the proven benefit of low dose clomiphene, at 12.5mgs (1/4 tablet for

convenience), or even less, I am now willing to maintain treatment, long term,

on same.

>

> Those who did not enjoy the subjective benefit of the on-treatment

testosterone increase may have been sensitive to the estrogen agonism (mimic)

half of the clomiphene, or zuclomiphene. Others experienced a sharp increase in

SHBG (again, from the estrogen half of the drug), and so would have needed

incredible--unattainable--gains in T just to produce bioavailable androgen

levels sufficient to make them feel good.

>

> Others simply have too much estrogen, either way.

>

> For the latter example of therapy failure (by subjective report), we will add

in aromatase inhibition, to hinder the conversion of T to E. For those with

elevated SHBG, we can add in some oral Danazol to lower same. Once resultant

dosages are titrated, we should be able to include all in the same cap, to save

the patient money.

>

> In my talks with Dr. Shippen, and well as Dr. Cabeca (Functional Medicine

physician extraordinaire) it is my belief residual toxic insult is the culprit

behind resumption of the hypogonadal state once clomiphene stimulation of the

HPTA is withdrawn.

>

> Anyone who experienced good increases in T with clomiphene, without

persistence upon drug withdrawal, is now welcome to go on clomiphene long-term.

Depending upon the case, we may add in anastrozole and/or oral Danazol.

>

> Keep in mind, " success " in previous restart attempt is defined merely as

sufficiently increased testosterone production. Whether you felt better at the

time or not is not reason for deferment. We can adjust estrogens and SHBG as

necessary to yield positive subjective response.

>

> My guys will tell you I have always been happy to try a restart. For those

with failure to restart (meaning the system did not keep running once we stopped

the clomiphene) we can try the new protocol. It would be great if we could NOT

use TRT to restore health and happiness. Just call , tell her what you

want, and make an appointment. We'll get started right away.

> Last edited by Dr. Crisler; 7 Hours Ago at 05:30 AM.

>

[Guest guest]

Yes I was thinking about everyone when I seen this. Dr. is a great person

and Dr. you can't find a better guy.

Co-Moderator

Phil

> From: marc200134470 <cfs38@...>

> Subject: Re: For My Guys Who Have Failed the HPTA-Restart

>

> Date: Monday, April 4, 2011, 1:52 PM

> Glad you posted that Phil, as I

> expect to see the results of my Clomid challenge this week.

>

> I am printing this off to take with me!

>

>

> >

> > This was posted today by Dr. .

> >

http://www.musclechatroom.com/forum/showthread.php?17612-For-My-Guys-Who-Have-Fa\

iled-the-HPTA-Restart

> > I have been thinking about this for a long time but

> waiting for this new drug to come out called Androxal.

> > http://www.drugs.com/nda/androxal_100208.html

> > It would be so dam nice to only take a pill everyday

> to keep TT levels up.

> >

> >

> =====================================================================

>

> > For My Guys Who Have Failed the HPTA-Restart

> > After a long Skype session a week ago with Dr.

> Shippen, I am rethinking the HPTA-Restart.

> >

> > A number of my patients have responded well to the

> clomiphene challenge. This shows the HPTA is indeed intact.

> Yet when the SERM-class drug was withdrawn, testosterone

> levels once again plummeted.

> >

> > With the proven benefit of low dose clomiphene, at

> 12.5mgs (1/4 tablet for convenience), or even less, I am now

> willing to maintain treatment, long term, on same.

> >

> > Those who did not enjoy the subjective benefit of the

> on-treatment testosterone increase may have been sensitive

> to the estrogen agonism (mimic) half of the clomiphene, or

> zuclomiphene. Others experienced a sharp increase in SHBG

> (again, from the estrogen half of the drug), and so would

> have needed incredible--unattainable--gains in T just to

> produce bioavailable androgen levels sufficient to make them

> feel good.

> >

> > Others simply have too much estrogen, either way.

> >

> > For the latter example of therapy failure (by

> subjective report), we will add in aromatase inhibition, to

> hinder the conversion of T to E. For those with elevated

> SHBG, we can add in some oral Danazol to lower same. Once

> resultant dosages are titrated, we should be able to include

> all in the same cap, to save the patient money.

> >

> > In my talks with Dr. Shippen, and well as Dr.

> Cabeca (Functional Medicine physician extraordinaire) it is

> my belief residual toxic insult is the culprit behind

> resumption of the hypogonadal state once clomiphene

> stimulation of the HPTA is withdrawn.

> >

> > Anyone who experienced good increases in T with

> clomiphene, without persistence upon drug withdrawal, is now

> welcome to go on clomiphene long-term. Depending upon the

> case, we may add in anastrozole and/or oral Danazol.

> >

> > Keep in mind, " success " in previous restart attempt is

> defined merely as sufficiently increased testosterone

> production. Whether you felt better at the time or not is

> not reason for deferment. We can adjust estrogens and SHBG

> as necessary to yield positive subjective response.

> >

> > My guys will tell you I have always been happy to try

> a restart. For those with failure to restart (meaning the

> system did not keep running once we stopped the clomiphene)

> we can try the new protocol. It would be great if we could

> NOT use TRT to restore health and happiness. Just call

> , tell her what you want, and make an appointment.

> We'll get started right away.

> > Last edited by Dr. Crisler; 7 Hours Ago at 05:30

> AM.

> >

>

>

>

>

> ------------------------------------

>

>