I figured out why I am having waves of Panic feelings.

[Guest guest]

Here is a copy of a post to a guy I just did to him about his Dr. switching him

to Shots from cream doing 100mgs every 3 days.

My Dr. told me doing this has drove up my E2 very high and my needing Arimidex

at very high levels has drove my levels down to low. The waves of panic

feelings I am getting are what I now call Hot Flash's from low E2 levels.

I use to gage my E2 levels by my night time and morning woood but going on Preg.

and Prog. cream this does not work any more. I can now get wood in my sleep

with very low levels of E2. Here is a cut and paste of the post I just did to

this guy.

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Yes go to the shots but I don't feel your using up your T as fast as you take

it. You have a Thyroid problem this can make your skin thicker and the cream is

not getting through your skin. I do 100 mgs of Test C every 3 days this is =

250 mgs./wk. My levels are as follows.

Testosterone, Total 917 range 250 – 1100 ng/dL.

Testosterone, Free 201.0 range 46.0 – 224.0 pg/mL.

Testosterone, Bioavailable 395.9 range 110.0 to 575.0 ng/dL.

SHBG 22 range 17 – 54 nmol/L.

I needed to take .5 to 1 mgs / day of Arimidex to keep my Estradiol in check.

I feel you need to start lower on your Test C shots you can do better doing them

2 x's a week or even every 3 days but start lower do labs and if your not

feeling better and your labs are to low go up on your dose. I would start with

150 mgs /wk. of 70 mgs 2x's / week even 60 mgs every 3 days.

I am now in the process of lowering my Test C dose due to making too much E2 yes

my levels are good but higher levels of E2 give me waves of Panic feeling even

attacks. Now it looks like I drove my E2 down to low. I just read the other

day at Dr. M forum going to low will cause Hot Flash's and this can feel like

waves of Panic.

So I went from 200mgs every 3 days to 80 mgs I was told on my next shot if I

have feeling of Panic or Hot Flash's on my next shot cut down to 60 mgs if this

helps go back up to 80 on he next one.

Well doing this is working I have not needed to take anything to lower my

Estradiol for 2 days now where before I was taking it everyday.

My Dr. use to use a lab with your ranges we stopped using them I now use Quest

labs there top of range is 1100 I feel with a range of 1600 your always going to

look low I did. You can't just go by lab numbers you need to go by how your

feel.

I can tell you doing to much Test C to keep my numbers up drove up my E2 and I

felt like crap from the high levels of Estraidol.

I gage my levels of Estradiol by my night time and morning wood but doing preg.

and prog. cream I can get wood in my sleep with very low levels or Estraidiol

the Prog. cream worked that good on me. So here I am thinking I feel like this

the waves of panic feels because my Estardiol is still to high. But now I read

that going to low can make you feel like this and my labs for Estradol were last

at 8 test before this 7.

Here is what Dr. M says about this.

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Drno

Physician, Psychiatrist

Join Date: Mar 2009

Location: Carmel, California

Posts: 611 Re: Aromatase inhibitors and their effect on mood

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Quote:

Originally Posted by chaos

I use arimidex as part of my regimen. I hear some prefer aromsin (sp?). Is one

better than the other for TRT, especially as it relates to mood?

Before I used the arimidex, I was very moody, but the arimidex resolved that.

Aromasin irreversibly binds to aromatase, knocking out the enzyme completely.

Adjusting dose can be trickier than with Arimidex since the enzyme it binds to

is completely inactivated. It is easy to knock out almost all of estradiol by

having too large a dose with Aromasin. It is almost all excreted in about a

week. Lowering estradiol dose excessively can bring about low estrogen problems

including reduced libido, hot flashes, increased cholesterol, etc.

Arimidex competes with testosterone for binding to aromatase. Adjusting its

effect involves increasing or decreasing the dose to get the desired binding

effect on Aromatase to increase or decrease estradiol levels. The problem for

Arimidex is that the duration of action very long. It takes up to 6 weeks to

stabilize the dose and level of estradiol.

Both are very expensive medications. Aromasin has to be taken every day since

its duration of action is much shorter than Arimidex. Arimidex can be taken once

a week to keep stable blood levels.

I can't vouch for one or the other. Arimidex seems to be the one chosen by most

practitioners. The ability to avoid daily dosing is a nice feature of Arimidex

once steady levels of estradiol are established. One can, for example just take

it on the day of a testosterone injection.

__________________

-

Romeo B. no, MD, physician, psychiatrist

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