Re: Tantrum, Meltdown,.. get worse when AC protocol has.....

January 6, 2010

Hi Sue, my son had these kinds of issues and I believe it was ALA lowering blood

sugar which caused the adrenals to be stressed. The episodes of behavior were

just his body's attempts to raise blood sugar (adrenaline) and what helped this

was small doses of lithium orotate during episodes of problem behavior, avoiding

sweets, and feeding him frequent protein snacks. Chromium with meals also helps

regulate blood sugar.

You could do some research on symptoms of low blood sugar and if you think it is

that, you might also want to consider avoiding taurine while he is on ALA

because it also lowers blood sugar. (My son's low blood sugar symptoms were

that he became very anxious, impatient, sometimes impulsive and aggressive and

when he ate, the behavior stopped.)

Liz

>

> Dears,

>

> My son behavior got worse after starting the Andy chelation, he throughs

things, has meltdown,.... more frequently, he gets eassily frustrated these

days, however i am positive that there is no sign of yeast because no dark sign

under his eyes or sillyness behavior.(he is on ChildBrain yeast protocol). I do

this protocol myself too, I feel more relax and positive. we just did the third

round (4 days on & 3 days off) should I just give him time to adjust himself, or

give him a break? Also he used to sleep 9-10 hr@ night, however now sometimes he

wakes up early morning (is that because I give his 6 a.m. dose. Other then that

he is OK. By the way he is 42lb, he is on 5mg DMSA & 5mg ALA plus ACE and other

supllements. I count on your feedback. I did in past three times DMPS IV, I

donot want back to that route again.

> Thanks inn advance.

> Sue

>

January 7, 2010

Liz, I think you're definitely on to something. My son is also having trouble

with reactions to ALA. I know it's mostly phenol related for him, but this

morning when he first awoke he was a nightmare, and then I sat him right down

and ended up feeding him a 3-course breakfast with 500mg chormium in between,

and after he was fine.

I think that early morning crash is the worst. Do you know why ALA lowers blood

sugar, if it gets better if you use lower doses of ALA, and if eventually the

body adjusts and the blood sugar problem is no longer an issue? Are the

adrenals being stressed from the mercury being pulled?

Thanks!

January 7, 2010

> My son behavior got worse after starting the Andy chelation, he throughs

things, has meltdown,.... more frequently, he gets eassily frustrated these

days, however i am positive that there is no sign of yeast because no dark sign

under his eyes or sillyness behavior.

For my son, the meltdowns and throwing things were signs of yeast. So I would

not be so certain he does not have a yeast problem.

>>Also he used to sleep 9-10 hr@ night, however now sometimes he wakes up early

morning

This was also a yeast symptom here.

Dana

January 7, 2010

Elyse, I think that lowering the ALA dose is a good idea. As I understand it,

the adrenals are stressed because they are involved in regulating insulin. My

son has glucose metabolism problems which I think cause insulin resistance.

When you already have high insulin and you are releasing MORE insulin by

chelating the mercury attached to it, you get the surge and crash cycles started

(insulin high, then below normal). I have found that the best way to prevent it

is eating a low sugar, low carb diet (and taking those supplements, lithium

orotate and chromium, as needed).

Here is what I have in my files on my computer about it:

Diabetes. 1999 Oct;48(10):2045-51.

Alpha-lipoic acid: effect on glucose uptake, sorbitol pathway, and energy

metabolism in experimental diabetic neuropathy.

Kishi Y, Schmelzer JD, Yao JK, Zollman PJ, Nickander KK, Tritschler HJ, Low PA.

Department of Neurology, Mayo Clinic and Foundation, Rochester, Minnesota 55905,

USA.

The peripheral nerve of experimental diabetic neuropathy (EDN) is reported to be

ischemic and hypoxic, with an increased dependence on anaerobic metabolism,

requiring increased energy substrate stores. When glucose stores become reduced,

fiber degeneration has been reported. We evaluated glucose uptake, nerve energy

metabolism, the polyol pathway, and protein kinase C (PKC) activity in EDN

induced by streptozotocin. Control and diabetic rats received lipoic acid (0,

10, 25, 50, 100 mg/kg). Duration of diabetes was 1 month, and alpha-lipoic acid

was administered intraperitoneally 5 times per week for the final week of the

experiment. Nerve glucose uptake was reduced to 60, s 37, and 30% of control

values in the sciatic nerve, L5 dorsal root ganglion, and superior cervical

ganglion (SCG), respectively, in rats with EDN. Alpha-lipoic acid

supplementation had no effect on glucose uptake in normal nerves at any dose,

but reversed the deficit in EDN, with a threshold between 10 and 25 mg/kg.

Endoneurial glucose, fructose, sorbitol, and myo-inositol were measured in

sciatic nerve. Alpha-lipoic acid had no significant effect on either energy

metabolism or polyol pathway of normal nerves. In EDN, endoneurial glucose,

fructose, and sorbitol were significantly increased, while myo-inositol was

significantly reduced. Alpha-lipoic acid had a biphasic effect: it

dose-dependently increased fructose, glucose, and sorbitol, peaking at 25 mg/kg,

and then fell beyond that dose, and it dose-dependently increased myo-inositol.

Sciatic nerve cytosolic PKC was increased in EDN. ATP, creatine phosphate, and

lactate were measured in sciatic nerve and SCG. Alpha-lipoic acid prevented the

reduction in SCG creatine phosphate. We conclude that glucose uptake is reduced

in EDN and that this deficit is dose-dependently reversed by alpha-lipoic acid,

a change associated with an improvement in peripheral nerve function.

Title: Reversal of hyperglycemic-induced defects in myo-inositol metabolism and

Na+/K+ pump activity in cultured neuroblastoma cells by normalizing glucose

levels.

Author: Yorek, M A : Dunlap, J A : Stefani, M R : son, E P

Citation: Metabolism. 1993 Sep; 42(9): 1180-9

Abstract: myo-Inositol accumulation and incorporation into phosphoinositides was

decreased in neuroblastoma cells chronically exposed to medium containing 30

mmol/L glucose or 30 mmol/L galactose. In addition, the intracellular content of

myo-inositol and phosphatidylinositol was decreased and the sorbitol or

galactitol content increased in cells cultured for 2 weeks in medium containing

30 mmol/L glucose or 30 mmol/L galactose, respectively. Na+/K+ adenosine

triphosphatase (ATPase) transport activity was also significantly decreased by

long-term exposure of neuroblastoma cells to medium containing 30 mmol/L glucose

or 30 mmol/L galactose. When glucose-conditioned cells were placed in medium

containing a normal glucose concentration for 24 hours, myo-inositol metabolism

and content, phosphatidylinositol levels, and Na+/K+ pump activity were restored

or completely returned to normal values. These functions were also significantly

improved, except for the phosphatidylinositol content, which was increased by

55%, when galactose-conditioned cells were incubated for 24 hours in

unsupplemented medium. The polyol content of the glucose- or

galactose-conditioned cells was also significantly reduced. Returning the cells

to normal glucose levels for 1 to 3 hours did not completely restore

myo-inositol metabolism. Improved myo-inositol metabolism and content, sorbitol

levels, and Na+/K+ ATPase transport activity were also obtained within 24 hours

when cells chronically exposed to medium supplemented with 30 mmol/L glucose

were placed in medium containing 30 mmol/L glucose and 0.4 mmol/L sorbinil. The

phosphatidylinositol content of these cells was improved by approximately 30%.

Cells prelabeled for 24 hours with [u-14C]sorbitol metabolize more than 50% of

the [u-14C]sorbitol during a 24-hour incubation in unsupplemented medium. These

studies conducted at the cellular level suggest that restoration of normal

myo-inositol metabolism, polyol content, and Na+/K+ pump activity altered by

hyperglycemic conditions occurs rapidly following normalization of glucose

concentration.

http://www.articlesbase.com/health-articles/mercury-can-directly-attach-itself-t\

o-insulin-342270.html

Mercury can attach itself directly to Insulin

It is also of importance to realize that this 50 percent response rate of

insulin-resistant patients doesn't take into account the profound effects of

minimizing the levels of toxins being released into your body. For example,

mercury (which is continuously released as vapor from dental amalgams, as I have

explained) has its own effect on insulin metabolism. Mercury can directly attach

itself to insulin, as well as to several other enzymes needed to process insulin

properly. This directly decreases the effect of the insulin that has been

released, causing the pancreas to release even more insulin to get the job done.

Thus the presence of mercury can be one more factor keeping insulin levels high

in the obese patient around the clock. Insulin-dependent diabetics must always

guard against low blood sugar after they have had their amalgams removed, since

the requirement for injected insulin often drops significantly after this

removal. Continuing the same amount of insulin supplementation after amalgam

removal can sometimes result in a dangerously low blood glucose level. It would

appear that mercury from any source can worsen the clinical problem of insulin

resistance that we are trying so hard to avoid. Therefore, it would seem likely

that the removal of toxins such as mercury would allow significantly more than

50 percent of obese people to get a favorable decline in their elevated insulin

levels from the suggestions being made. At this point, it is also crucial to

realize that any agent or factor that damages or lessens immune function will

help mercury and other toxins to exert their toxic effects. Generally, the

immune system acts to neutralize toxins, and anything that compromises the

immune system magnifies the toxic effect. For this reason, immune

system-damaging substances such as refined sugar can have a similar but less

direct toxic effect on the body as mercury, since it allows whatever levels of

mercury are present to be less neutralized and have a greater effect. This does

not mean that sugar is as toxic as mercury. But it does mean that labeling a

container of sugar with a skull and crossbones might not be overdoing it!

>

> Liz, I think you're definitely on to something. My son is also having trouble

with reactions to ALA. I know it's mostly phenol related for him, but this

morning when he first awoke he was a nightmare, and then I sat him right down

and ended up feeding him a 3-course breakfast with 500mg chormium in between,

and after he was fine.

>

> I think that early morning crash is the worst. Do you know why ALA lowers

blood sugar, if it gets better if you use lower doses of ALA, and if eventually

the body adjusts and the blood sugar problem is no longer an issue? Are the

adrenals being stressed from the mercury being pulled?

>

> Thanks!

>

January 7, 2010

I want to also mention that if your child is on too high a dose and experiencing

these kinds of symptoms, the symptoms may be masking any gains being made. For

awhile, I was discouraged that my son was not seeming to be a responder but it

turned out that he did make gains once we took a break and lowered his dosing

when we started up again.

> >

> > Liz, I think you're definitely on to something. My son is also having

trouble with reactions to ALA. I know it's mostly phenol related for him, but

this morning when he first awoke he was a nightmare, and then I sat him right

down and ended up feeding him a 3-course breakfast with 500mg chormium in

between, and after he was fine.

> >

> > I think that early morning crash is the worst. Do you know why ALA lowers

blood sugar, if it gets better if you use lower doses of ALA, and if eventually

the body adjusts and the blood sugar problem is no longer an issue? Are the

adrenals being stressed from the mercury being pulled?

> >

> > Thanks!

> >

January 7, 2010

He probably needs more adrenal cortex. Many children who have stressed adrenals

exhibit a worsening of those symptoms on rounds because chelation is stressful

tot he adrenals. ACE got rid of tantrums for my son kid. I don't know how much

your giving him of this, but I'd give more.

Jan