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Hi,

My insurance company denied my script for Humira because I have not tried Enbrel yet. Can someone tell me if Enbrel causes pain during injection like Humira? Also any side effects you have experienced.

If Enbrel doesn't start to work after 3 months, my dr can call it a failure and I can get Humira.

Is Humira really that much better than Enbrel?

Thanks for any advice.

Vicki

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Vicki,

I was on Enbrel. It stopped working for me after about nine months...but then again so does everything else.

I took Enbrel twice a week. This is the form you mix fresh every time you inject it. It did not burn or sting like Humira. I was told the preservative in Humira is what makes it burn.

There is also a 50mg once a week pre-mixed form of Enbrel. But again I have heard from many that use it that it also burns just like Enbrel.

If enbrel is the drug you must start on I would pick the twice a week dose that you have to mix. You have the option of starting out taking the shots twice a week...and most docs for convience will let you take both shots on the day of your choice at one time.

The only side effects I had from Enbrel was a site injection reaction. My skin turned red, got a rash and a hard lump like a large insect bite. This happened like two times and then I stopped taking enbrel. It was toward the end of me taking it.

Toni in Texas

In a message dated 9/20/2005 11:10:04 A.M. Central Daylight Time, Rheumatoid Arthritis writes:

Date: Mon, 19 Sep 2005 13:15:31 -0500 (Central Standard Time) From: "Vicki" <hoyt91@...>Subject: EnbrelHi,My insurance company denied my script for Humira because I have not triedEnbrel yet. Can someone tell me if Enbrel causes pain during injection likeHumira? Also any side effects you have experienced.If Enbrel doesn't start to work after 3 months, my dr can call it a failureand I can get Humira.Is Humira really that much better than Enbrel?Thanks for any advice.Vicki

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Hi Vicky,My experience with Enbrel was short, it worked for a short time and then not anymore. I am on Humira now and it is not doing too much either... The two shot Enbrel that you mix yourself is not bad, no pain. The pre-mixed 50 mg was about the same as Humira as far as the burning goes. Good luck on whatever you try.SamOn Sep 19, 2005, at 11:15 AM, Vicki wrote: Hi, My insurance company denied my script for Humira because I have not tried Enbrel yet.  Can someone tell me if Enbrel causes pain during injection like Humira?  Also any side effects you have experienced.   If Enbrel doesn't start to work after 3 months, my dr can call it a failure and I can get Humira.   Is Humira really that much better than Enbrel?   Thanks for any advice. Vicki <IMSTP.gif>

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In a message dated 9/19/2005 1:22:51 P.M. Central Standard Time, hoyt91@... writes:

Hi,

My insurance company denied my script for Humira because I have not tried Enbrel yet. Can someone tell me if Enbrel causes pain during injection like Humira? Also any side effects you have experienced.

If Enbrel doesn't start to work after 3 months, my dr can call it a failure and I can get Humira.

Is Humira really that much better than Enbrel?

Thanks for any advice.

Vicki

Hi,

I just started Enbrel 7 weeks ago, right after I had my first injection of MTX that almost killed me. While I still had MTX in my system the Enbrel worked great. The last couple of injections did burn for a short time, but I was happy that it was working and didn't have the

yucky side effects that MTX and Arava have.

Right now I am flaring in my wrists and elbows as I am ill with my 'Annual Labor Day Weekend Bronchitis'. I am trying to find a doctor who will prescribe an antibiotic for me, as I am allergic to most of them. My Rheumy wouldn't prescribe one for me. : (

Trying to pinch fat, hold the needle still and push the plunger are difficult for me to try to do

at the same time, but since I am only injecting once a week it's not as bad as the pain and

disability that I was in before being diagnosed.

Becky

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In a message dated 9/20/2005 11:26:05 P.M. Central Standard Time, hoyt91@... writes:

-------Original Message-------

From: StarsHutch@...

Date: 09/20/05 22:26:32

Rheumatoid Arthritis

Subject: Re: Enbrel

Does MTX stand for methotrexate or another drug? I take methotrexate but I've been pretty bad all summer. I left a message for my Dr to fax a new script for Enbrel to the pharmacy and he sent the Humira script again! This is so frustrating. I'll have to call again and the lady at the pharmacy said she would call and try to expedite the script. I've been working on this for almost 3 weeks...gggrrrrr

MTX = Methotrexate. Awful stuff, didn't work all that well either.

Becky

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-------Original Message-------

From: StarsHutch@...

Date: 09/20/05 22:26:32

Rheumatoid Arthritis

Subject: Re: Enbrel

Does MTX stand for methotrexate or another drug? I take methotrexate but I've been pretty bad all summer. I left a message for my Dr to fax a new script for Enbrel to the pharmacy and he sent the Humira script again! This is so frustrating. I'll have to call again and the lady at the pharmacy said she would call and try to expedite the script. I've been working on this for almost 3 weeks...gggrrrrr

Vicki

Hi,

I just started Enbrel 7 weeks ago, right after I had my first injection of MTX that almost killed me. While I still had MTX in my system the Enbrel worked great. The last couple of injections did burn for a short time, but I was happy that it was working and didn't have the

yucky side effects that MTX and Arava have.

Right now I am flaring in my wrists and elbows as I am ill with my 'Annual Labor Day Weekend Bronchitis'. I am trying to find a doctor who will prescribe an antibiotic for me, as I am allergic to most of them. My Rheumy wouldn't prescribe one for me. : (

Trying to pinch fat, hold the needle still and push the plunger are difficult for me to try to do

at the same time, but since I am only injecting once a week it's not as bad as the pain and

disability that I was in before being diagnosed.

Becky

--- USFamily.Net - $8.25/mo! -- Highspeed - $19.99/mo! ---

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I don't feel that the MTX does anything for me either, but I am told

that as a DMARD (Disease modifying anti rheumatic drug), its still

important to take to prevent joint destruction. I know with these

abatacept infusions, that still want me to stay on the MTX.

Gentle Hugs to all,

Miriam

>

>

> In a message dated 9/20/2005 11:26:05 P.M. Central Standard Time,

> hoyt91@u... writes:

>

>

>

> -------Original Message-------

>

>

> From: _StarsHutch@a..._ (mailto:StarsHutch@a...)

> Date: 09/20/05 22:26:32

> _Rheumatoid Arthritis _

> (mailto:Rheumatoid Arthritis )

> Subject: Re: Enbrel

>

> Does MTX stand for methotrexate or another drug? I take

methotrexate but

> I've been pretty bad all summer. I left a message for my Dr to

fax a new

> script for Enbrel to the pharmacy and he sent the Humira script

again! This is

> so frustrating. I'll have to call again and the lady at the

pharmacy said she

> would call and try to expedite the script. I've been working on

this for

> almost 3 weeks...gggrrrrr

>

>

> MTX = Methotrexate. Awful stuff, didn't work all that well

either.

>

>

>

> Becky

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I've taken MTX - methotrexate for over 10

years with no problems. It's worked for me up until this summer. Only

side effects were a little fatigue and nausea...and that was only when

I was taking 6 or more pills a week...if I was under 6 pills I didn't

have any fatigue. Like any other drug, some will get good results and

some won't.

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

Maggie

http://www.4HockeyFans.com

http://www.4FloridaHockey.com

MSN: Maggies1429

AOL: Maggies85

StarsHutch@... wrote:

In a message dated 9/20/2005 11:26:05 P.M. Central Standard

Time, hoyt91@... writes:

-------Original

Message-------

From: StarsHutch@...

Date:

09/20/05 22:26:32

Rheumatoid Arthritis

Subject:

Re: Enbrel

Does MTX stand for methotrexate or another drug? I

take methotrexate but I've been pretty bad all summer. I left a

message for my Dr to fax a new script for Enbrel to the pharmacy and he

sent the Humira script again! This is so frustrating. I'll have to

call again and the lady at the pharmacy said she would call and try to

expedite the script. I've been working on this for almost 3

weeks...gggrrrrr

MTX = Methotrexate. Awful stuff, didn't work all that well

either.

Becky

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  • 7 months later...
Guest guest

I take Humira. I do believe it has stopped, or at least slowed, the

erosion in my joints. I haven't had any increase with any kind of

infections.

>

> I'm thinking of asking my rheumy about Enbrel when I see her next

week.

> I think I need something more than the MTX I've been taking. I'm

> nervous about infections, though. I've had one cold in 2 years,

haven't

> missed a day of work. But my hands and feet hurt and I'm SO tired

again.

> My last X-rays revealed an erosion despite being on MTX. Thoughts

about

> biologic safety? Your own experiences with infection?

>

> Sierra

>

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Guest guest

Hi,

I've been on Enbrel for 3 years and have had no serious infections. I

have had to stop the injections a handful of times when I've gotten

colds or upper respiratory bugs but they were no worse than w/o Enbrel

and the drug worked really well for me until just the last few months.

Coicidentally, I'm heading to the rheumy this afternoon and plan to

finally take him up on his offer of remicade. I think it's time.

Enbrel brought me to about 90% of normal, he thinks Remicade will be

the final answer. My concern is after the remicade stops working,

what's next? He indicates Humira is about as effect as Enbrel & that

Remicade is most powerful.

lottie

>

> I'm thinking of asking my rheumy about Enbrel when I see her next week.

> I think I need something more than the MTX I've been taking. I'm

> nervous about infections, though. I've had one cold in 2 years, haven't

> missed a day of work. But my hands and feet hurt and I'm SO tired again.

> My last X-rays revealed an erosion despite being on MTX. Thoughts about

> biologic safety? Your own experiences with infection?

>

> Sierra

>

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Guest guest

I’ve been on Methotrexate for 4

years and Remicade for about 3-1/2 years and so far haven’t had anything

significant in the way of colds and have never had to skip an infusion because

of illness. I don’t get checked regularly for new erosions but my

doctor is satisfied that they have been slowed or stopped.

As for safety of biologicals, I think the

warnings about lymphoma and heart problems do not reflect a comparison with others

with severe RA, but a comparison with the general public. Other studies

of people with severe RA but not on biologicals show about the same increase in

these problems so I don’t think the biologicals are responsible for the

problems stated in the warnings. The problem with activating latent TB

seems to be real, however, and a TB test before starting the biologicals is

good because this activation can be avoided with proper pretreatment. God

bless.

From: Rheumatoid Arthritis [mailto:Rheumatoid Arthritis ] On Behalf Of snowdrift52003

Sent: Wednesday, April 26, 2006

4:30 AM

Rheumatoid Arthritis

Subject:

Enbrel

I'm thinking of asking my rheumy about Enbrel when I see her next week.

I think I need something more than the MTX I've been taking. I'm

nervous about infections, though. I've had one cold in 2 years, haven't

missed a day of work. But my hands and feet hurt and I'm SO tired again.

My last X-rays revealed an erosion despite being on MTX. Thoughts about

biologic safety? Your own experiences with infection?

Sierra

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Guest guest

I love Remicade although it doesnt seem to be working as well as in the past. That is my fault though because I waited far too long to have my last infusion. Almost 16 weeks. I think my body loses memory or TNF binding capacity. I havent had problems with infection, though I am slow to heal from a bruise etc but I am anemic. My benefit originally in 2000 was almost instantaneous. I didnt even take MTX because I felt so much better. It will help with fatigue. Make sure you get a bone scan to be sure you arent suffering from Osteoporosis. MTX can leach folic acid and calcium out of you. Take a super multi. Hugs, Deborah

On 4/26/06, snowdrift52003 <snowdrift52003@...> wrote:

I'm thinking of asking my rheumy about Enbrel when I see her next week.I think I need something more than the MTX I've been taking. I'm

nervous about infections, though. I've had one cold in 2 years, haven'tmissed a day of work. But my hands and feet hurt and I'm SO tired again.My last X-rays revealed an erosion despite being on MTX. Thoughts about

biologic safety? Your own experiences with infection?Sierra

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Guest guest

Hi Sierra, This is Steph in VA. I have had RA for 6.5 years & have been taking Remicade for 6 years. Like Harold, I have not had any infections or allergic reactions to Remicade. I do not have any concerns about the safety of Remicade. I also agree with Harold about the risk of TB. The TB test requirement came out after I started Remicade, but I have since been tested. In the time I have been on Remicade I have delayed treatment only once -- but that was for a car accident. As an aside, we as arthritis patients are at a higher risk for a number of illnesses, no one's safety is guaranteed. Recently my friend's very healthy 28 year old husband had a heart attack & my 48 year old very healthy rheumy just died of a heart attack last month. Weighly the risks vs. benefits of medications is a big decision for us. I chose to take the risk

and I have been very satisfied with the benefits of my treatment. Take care, Steph in VA I'm thinking of asking my rheumy about Enbrel when I see her next week. I think I need something more than the MTX I've been taking. I'm nervous about infections, though. I've had one cold in 2 years, haven't missed a day of work. But my hands and feet hurt and I'm SO tired again.My last X-rays revealed an erosion despite being on MTX. Thoughts about biologic safety? Your own experiences with infection?Sierra

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