Autism Causation - Genetic Vs. Mercury

[Guest guest]

Autism - Genetic Vs. Mercury

Would anyone like to have a discovery conversation about genetics and autism as

compared to mercury induced autism symptomatology. Has anyone considered that

certain genetics can predispose an individual to certain sensitivities of and

relating to mercury. I am not a scientist so this may already be common sense to

you.

I understand that speaking in pathological terms might offend at least someone

on this forum. I am trying to figure it out in an observed thinking style.

Young

[Guest guest]

Andy on Genetics and Autism:

Parent wrote: Is this true? I thought the Jill research didn't show MTHFr

mutations at any statistically significant rate in Autistics vs the general

population.

Andy:

There are a few mutations which show a " suceptability " to mercury.

According to the Geiers, MTHFR is one of them. I have read other

doctors disagree with this.

We need to talk about reality versus alternative medicine psychosis here.

" mutation " is a very technical word being used very much out of

context here. If they knew what they were doing they would say

" allele. " Let me explain the proper terminology.

A GENE is some DNA that codes for a protein product and that

occupies a specific slot or slots on a specific chromosome. Humans have 25,000

to 30,000 genes. They have lots of other DNA that does something else. Genes

make proteins, if it doesn't code for a protein it isn't a gene.

As far as is known at present with only a relatively small number

of human beings having been sequenced, there are on average 14

different variants of each gene (no doubt the average will go up as more people

get sequenced). These variants are called ALLELES. Each allele codes for a

protein with a (usually very slightly) different sequence than each other allele

of that gene.

Thus you have, for example, the gene for eye color. Every person

has 2 copies, one from the mother and one from the father. There are

alleles for brown, blue, and green. Depending on what combination

they get they have a specific eye color.

A MUTATION is where the DNA sequence of one allele is changed and

results in another allele. Thus if you think at some point all

humans were brown eyed, the blue and green eye genes are " mutations " of the

brown eyed gene. However the term mutation generally also means

RECENT change, low population incidence, and is generally perceived as

inferior. ALLELES with a high population incidence are those

mutations which are NOT inferior, may even convey some survival

advantage, and come to have a significant incidence in the population.

So all this MTHFR stuff we are talking about is really an issue of

which alleles of it are out there, and whether there is an increased

incidence of some allele in the autistic population.

If there is increased incidence, that has no real implication that

it is causal or increases susceptibility. E. g. what if one allele of

MTHFR just makes parents be more willing to comply with doctor's

orders so they get their kids vaccinated and the other people are

less likely to?

There are genotypes (combinations of alleles) that do very strongly

correlate with autism - two are XY (boys more likely than girls)

and Rh +- (since babies of rhogam receiving mothers are more likely to

be affected).

It is very important to have some perspective and look at the big

picture before getting involved in how everything causes autism and

chasing non-treatments to the exclusion of things that might help.

Given that there are such obvious problems in Dr. ' cysteine

data I would take anything she says with a grain of salt until that is

clarified, but detecting a specific allele is actually pretty black

and white if proper testing is performed so I would think it likely

she did get this one right.

Andy

http://onibasu.com/archives/am/178386.html

>

> Autism - Genetic Vs. Mercury

>

> Would anyone like to have a discovery conversation about genetics and autism

as compared to mercury induced autism symptomatology. Has anyone considered that

certain genetics can predispose an individual to certain sensitivities of and

relating to mercury. I am not a scientist so this may already be common sense to

you.

>

> I understand that speaking in pathological terms might offend at least someone

on this forum. I am trying to figure it out in an observed thinking style.

>

> Young

>

[Guest guest]

No thank you, we are too busy recovering our guy to worry about what genetically

predisposed him to asd.  Maybe when he's recovered............

nancy j

a child is diagnosed with

asd every 20 seconds

From: <nathan@...>

Subject: [ ] Autism Causation - Genetic Vs. Mercury

Date: Monday, July 12, 2010, 11:43 PM

 

Autism - Genetic Vs. Mercury

Would anyone like to have a discovery conversation about genetics and autism as

compared to mercury induced autism symptomatology. Has anyone considered that

certain genetics can predispose an individual to certain sensitivities of and

relating to mercury. I am not a scientist so this may already be common sense to

you.

I understand that speaking in pathological terms might offend at least someone

on this forum. I am trying to figure it out in an observed thinking style.

Young

[Guest guest]

In idea genetic predisposition to mercury sensitivities and even environmental,

dietary and otherwise impurities could result in a gene therapy. Again I'm not a

scientist and this is a discovery conversation.

>

> No thank you, we are too busy recovering our guy to worry about what

genetically predisposed him to asd.  Maybe when he's recovered............

>

> nancy j

>