Guest guest Posted April 9, 2010 Report Share Posted April 9, 2010 I'm guessing I'm an over-methylator with anxiety. I tried SAMe once, but made the mistake of splitting the tablet & gave big time heartburn. Have a history of gastritis, so have to avoid citrus. It made me feel relaxed & lessened joint pain. I have been low in b-12. What is a trusted brand w the lowest dose? Thanks, Kathy From: jeffnteddi <hopefulchild99-asd@...> Subject: [ ] Re: Do you know any natural mood stabilizer for autism? 4/9  Here's supporting information regarding SAMe, B12, folate... http://www.psycom. net/depression. central.same. html EXCERPT: This review focuses on the biochemical and clinical aspects of methylation in neuropsychiatric disorders and the clinical potential of their treatment with ademetionine (S-adenosylmethioni ne; SAMe). SAMe is required in numerous transmethylation reactions involving nucleic acids, proteins, phospholipids, amines and other neurotransmitters. The synthesis of SAMe is intimately linked with folate and vitamin B12 (cyanocobalamin) metabolism, and deficiencies of both these vitamins have been found to reduce CNS SAMe concentrations. Both folate and vitamin B12 deficiency may cause similar neurological and psychiatric disturbances including depression, dementia, myelopathy and peripheral neuropathy. SAMe has a variety of pharmacological effects in the CNS, especially on monoamine neurotransmitter metabolism and receptor systems. SAMe has antidepressant properties, and preliminary studies indicate that it may improve cognitive function in patients with dementia. Treatment with methyl donors (betaine, methionine and SAMe) is associated with remyelination in patients with inborn errors of folate and C-1 (one-carbon) metabolism. These studies support a current theory that impaired methylation may occur by different mechanisms in several neurological and psychiatric disorders. Best wishes! Theodora -m-Mercury, Momlaw@ wrote: > > > > We are also looking for something that works more steadily. SAM-e can be > > wonderful and soothing for many kids (and adults--try it!). It's expensive > > but we have found VERY helpful, particularly for anger, anxiety and > > agitation. > > > > We don't use it everyday, and frankly, given our history with supplements, > > I would be concerned that the good effects would wane if used daily. > > Better to have something effective for those really 'hostile' moments. > > > > > > > > > > In a message dated 4/9/2010 8:32:37 A.M. Central Daylight Time, > > mkpa.us@ writes: > > > > > > > > > > Hello everybody, > > My son is autistic and I am looking for some natural medicine to help the > > behavior - natural mood stabilizer. I would like to know if somebody has > > some suggestion. > > Thanks > > Ana > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 10, 2010 Report Share Posted April 10, 2010 Good Morning Theodora, Thanks your help! I am loving this group. Best Ana (Brazil) > > > > > > We are also looking for something that works more steadily. SAM-e can be > > > wonderful and soothing for many kids (and adults--try it!). It's expensive > > > but we have found VERY helpful, particularly for anger, anxiety and > > > agitation. > > > > > > We don't use it everyday, and frankly, given our history with supplements, > > > I would be concerned that the good effects would wane if used daily. > > > Better to have something effective for those really 'hostile' moments. > > > > > > > > > > > > > > > In a message dated 4/9/2010 8:32:37 A.M. Central Daylight Time, > > > mkpa.us@ writes: > > > > > > > > > > > > > > > Hello everybody, > > > My son is autistic and I am looking for some natural medicine to help the > > > behavior - natural mood stabilizer. I would like to know if somebody has > > > some suggestion. > > > Thanks > > > Ana > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
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