Guest guest Posted August 14, 2010 Report Share Posted August 14, 2010 On the Mito Action website, Dr. Irina Anselm, a pediatric neurologist, from Children’s Hospital Boston discussed updates in the approaches to the treatment of mitochondrial disease in an audio webcast. Dr. Anselm advocates starting CoQ10 first, followed by creatine monohydrate for children with mitochondrial disease. 8 To listen to the entire audio of her webcast where she discusses updates on mitochondrial disease treatment approaches, visit www.mitoaction.org where the webcast is available.  1.      Tischon brand CoQ10 – highly recommended by the top pediatric mito. doctors. Tischon CoQ10 is the most bioavailable version available at this time and has recently been awarded an orphan drug designation for treatment of mitochondrial cytopathies. Tischon is much more bioavailable than other over the counter brands of CoQ10.  MitoMedica H2Q (ubiquinone) – available in gel caps and powder form.  MitoMedica is Tischon’s most allergenic free brand.  Cyto Q Qel (ubiquinone) – available in Q Gel Forte (15 mg), Q Gel Mega (60 mg), Q Gel Ultra (100 mg) and Q Gel Double strength (200 mg).   In a recent article written by six of the top mitochondrial doctors in the field of mitochondrial medicine, they outline A Modern Approach to the Treatment of Mitochondrial Disease. In this article, they state that, “Powder formulations of CoQ10 have very poor intestinal absorption.†5 And they further stated that ubiquinol versions of CoQ10 are three to five times better absorbed than ubiquinone.â€Â      Quinogel (ubiquinol) – available in gel caps 50 mg and 100 mg  Liquid QH Liposomal Ubiquinol – this liquid version is one of the most bioavailable versions they sell and is highly recommended by mito doctors if severe fatigue is an issue.  Tischon CoQ10 can be purchased at, www.epic4health.com  In this same article, they also stated that the most solubilized bioavailable formulations of CoQ10 are preferred [which the Tischon brand is] and absorption is improved when taken with a meal. 5   2.     Creatine Monohydrate- The top mito doctors are recommending a product called Neotine which is a form of creatine monohydrate and it is available at www.neotine.com  Solace Nutrition also makes creatine monohydrate. The product is called Cytotine and it is available at www.solacenutrition.com Some experts recommend 1/3 the dose if it’s a Solace brand because it’s super bioavailable.  There have been anecdotal reports of children having increased stimming and diarrhea if the dose of creatine is too high.  When using creatine monohydrate it is very important that AST/ALT (kidney and liver functions) are monitored by your supervising physician regularly.  3.    Carnitor®/ generic levo-carntine – dosed 2-3 times daily, not all in one dose. 5  4.   Riboflavin (B2) – Solace Nutrition makes a riboflavin called Cyto B2 that is highly bioavailable. It may be best given at bedtime.  MitoMedica Riboflavin mini-capsules 100 mg- can be purchased at, www.epic4health.com  5.     ALA (alpha lipoic acid) – an antioxidant  6.     Leucovorin Calcium (in some patients) – which is the folinic acid medication of choice for some mito. docs.  Discuss these with your physician. From: danasview <danasview@...> Subject: [ ] Re: Mito cocktail components? Date: Saturday, August 14, 2010, 2:38 PM  > Can someone please refresh my memory on all the supplement components of the Mito Cocktail? I wrote what my son needed here http://www.danasview.net/mar05.htm Dana Quote Link to comment Share on other sites More sharing options...
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