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Paradoxical to anything calming/ screaming!

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Anyone have any idea why my child has a paradoxical effect to anything that is

to calm him down or help him sleep. We've tried melatonin, gaba, 5htp, valium,

ativan, benadryl, rescue remedy, l-theanine......

Every thing we tried gave himĀ  he had either no effect or the opposite effect.

Constant screaming anyone know why?????

Kate

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