fix PDFs: Start of autistic symptoms in infants parallels CDC's vaccination schedule for infants and toddlers

[Guest guest]

Here, Table 3 replaces erroneous reference to Figure 3 - still on page 5.

As you look at Table 3, page 5 of the Ozonoff et al study

<http://download.journals.elsevierhealth.com/pdfs/journals/0890-8567/PIIS0890856\

709000318.pdf>,

compare it with CDC's vaccine table

<http://www.cdc.gov/vaccines/recs/schedules/downloads/child/2010/10_0-6yrs-sched\

ule-pr.pdf>,

both of which should be saved and preserved.

We often hear " coincidence " in regard to vaccination-autism regressions,

but that is merely speculation and needs be proven. In contrast, (as

J.B. Handley noted in a grandly understated blog) the study's findings

match profoundly well with parental reports of vaccination-related

regression, with the original CDC " Generation Zero " findings

(Verstraeten et al 1999 unpublished until after data were deliberately

diluted); with Goodman and Gallagher's more recent findings, with Geier

& Geier et al findings, etc. Given background variables like

locale-pollution, in-home pollution, and family genetics, and other

factors, a range of onsets and gradualistic regressions (see Table 3)

would be anticipated and appears in the small-N but important findings

of Ozonoff et al

<http://download.journals.elsevierhealth.com/pdfs/journals/0890-8567/PIIS0890856\

709000318.pdf>.

Heres the abstract with several additonal comments following the abstract.

*A Prospective Study of the Emergence of Early Behavioral Signs of Autism*

Sally Ozonoff et al.

J. Am. Acad. Child Adolesc. Psychiatry, 2010;49(3):258 --268.

available here

<http://download.journals.elsevierhealth.com/pdfs/journals/0890-8567/PIIS0890856\

709000318.pdf>

Objective: To examine prospectively the emergence of behavioral signs of

autism in the first years of life in infants at low and high risk for

autism. Method: A prospective longitudinal design was used to compare 25

infants later diagnosed with an autism spectrum disorder (ASD) with 25

gender-matched low-risk children later determined to have typical

development. Participants were evaluated at 6, 12, 18, 24, and 36 months

of age. Frequencies of gaze to faces, social smiles, and directed

vocalizations were coded from video and rated by examiners. Results: The

frequency of gaze to faces, shared smiles, and vocalizations to others

were highly comparable between groups at 6 months of age, but

significantly declining trajectories over time were apparent in the

group later diagnosed with ASD. Group differences were significant by 12

months of age on most variables. Although repeated evaluation documented

loss of skills in most infants with ASD, most parents did not report a

regression in their child's development [/**/]. Conclusions: These

results suggest that behavioral signs of autism are not present at

birth, as once suggested by Kanner [/*/], but emerge over time through a

process of diminishment of key social communication behaviors. More

children may present with a regressive course than previously thought,

but parent report methods do not capture this phenomenon well.

Implications for onset classification systems and clinical screening are

also discussed.

*** Rate of autism is different circa this study (2010), in contrast

with Kanner <http://en.wikipedia.org/wiki/Leo_Kanner>'s original

observations. The autism cases Kanner described may have been present

from birth and may have been other than regressive autisms as developed

in more recent decades.

**** Parents learn that individual children develop at a rate different

for each child, although group trends and average stages have been

described. Some physicians may teach young parents that some delay is

normal from some individual children, thereby masking parents'

observations and reports of a child's atypical developmental progress.

At first glance, the study's findings are remarkably parallel to the

CDC's timing of infant vaccinations (here

<http://www.cdc.gov/vaccines/recs/schedules/downloads/child/2010/10_0-6yrs-sched\

ule-pr.pdf>).

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