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I rhink there are some relatively recent opinions posted by Andy which still say

he believes OSR isn't a safe option.

>

> I just got this post from the autism action plan group and thought Id post

here for any one interested.

>

> Karla

>

> -- The following message was posted by Kurt Woeller (DrKurtWoeller) in the

" Other Therapies " category. All replies to this e-mail will be sent to the

group --

>

> For those of you interested in Dr. Haley's response regarding OSR and its 1/2

life. I did receive an email back from Dr. Haley. Here was his response:

>

> * " OSR has a plasma and organ half-life of 6 to 7 hours in test animals (rats).

It peaks at 2 hours after ingestion in the plasma and all organs we tested

(brain, kidney, liver, intestines, bone marrow, epidermal and internal fat

tissues). At 24 hours after ingestion the plasma and organ levels are down to

4-12% of the peak values at 2 hours. I have taken OSR three times daily for over

a year, early morning, noon and evening based on the 6-7 hour plasma half life.

My health analysis is excellent, I have no build up of OSR, no loss of essential

minerals (we checked this out long ago), and I feel quite healthy. I have been

taking OSR 3 ½ years. My blood glutathione is 1580 whereas the average is 669,

so I am in good shape with regards to this oxidative stress marker----and I had

no signs of any other oxidative stress markers at my last physical. This

information has been on our website for quite a long time. I think the comments

of Dr. Cutler are quite old and keep being brought up by those that may not want

OSR to be used. "

> *

>

> I hope this helps,

>

> Dr. Woeller

>

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I would agree. We are doing AC protocol and dont plan on changing that. Id like

to see alot more data beyond the rats and Dr Haley as test subjects.

But I also know the topic comes up periodically here and since this was a recent

response, I wasnt sure if there was anything new to look at.

Karla

> >

> > I just got this post from the autism action plan group and thought Id post

here for any one interested.

> >

> > Karla

> >

> > -- The following message was posted by Kurt Woeller (DrKurtWoeller) in the

" Other Therapies " category. All replies to this e-mail will be sent to the

group --

> >

> > For those of you interested in Dr. Haley's response regarding OSR and its

1/2 life. I did receive an email back from Dr. Haley. Here was his response:

> >

> > * " OSR has a plasma and organ half-life of 6 to 7 hours in test animals

(rats). It peaks at 2 hours after ingestion in the plasma and all organs we

tested (brain, kidney, liver, intestines, bone marrow, epidermal and internal

fat tissues). At 24 hours after ingestion the plasma and organ levels are down

to 4-12% of the peak values at 2 hours. I have taken OSR three times daily for

over a year, early morning, noon and evening based on the 6-7 hour plasma half

life. My health analysis is excellent, I have no build up of OSR, no loss of

essential minerals (we checked this out long ago), and I feel quite healthy. I

have been taking OSR 3 ½ years. My blood glutathione is 1580 whereas the average

is 669, so I am in good shape with regards to this oxidative stress

marker----and I had no signs of any other oxidative stress markers at my last

physical. This information has been on our website for quite a long time. I

think the comments of Dr. Cutler are quite old and keep being brought up by

those that may not want OSR to be used. "

> > *

> >

> > I hope this helps,

> >

> > Dr. Woeller

> >

>

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An unpublished study on a dozen mice does not adequately establish a half life

in humans to make it ethical to use something in them.

Calling information " old " suggests the doctor is a liberal arts major and views

this all as fad and fashion, not as a technical field where he is giving

dangerous chemicals to living humans. This is the attitude that led to the

autism holocaust in the first place - doctors didn't accept that when you

administered a toxic dose of mercury in vaccines it was toxic even if they

didn't mean to hurt anyone.

Otherwise it is a response devoid of information. This is not surprising since

all the points in my prior critique are valid and correct, so there is no

possible legitimate response to them.

I also don't think an N=1 human study is good enough to rely on when giving what

is in essence an unapproved experimental new drug being sold as a nutritional

supplement to children. After all, the study that caused Heroin to be turned

loose on the world as a nonaddictive substitute for morphine actually had THREE

people in it - who by chance turned out to be among the 7% of the population not

subject to opiate addiction - and you can imagine the havoc that wreaked in the

1920's. It was so bad heroin continues to be illegal in the US to this day.

Dr. Haley admitted lack of relevant technical knowledge (and demonstrated it as

well). Dr. Woeller is not providing any technical information. His assurance

that OSR is safe seems eerily similar to the assurances most of you got that

vaccines are totally safe when your pediatrician turned your kid autistic.

I do hope that someone will bother to respond to my points with relevant

technical details instead of advertizing hype. Until then I hope that parents

have learned from their heartbreaking experiences and won't let yet another

doctor hurt their kid by just promising 'everything is fine' without providing

the technical back-up to support that claim.

Andy

http://www.noamalgam.com/index.html

Amalgam Illness: Diagnosis and Treatment

http://www.noamalgam.com/hairtestbook.html

Hair Test Interpretation: Finding Hidden Toxicities

http://www.noamalgam.com/nourishinghope.html

Nourishing Hope for Autism: Nutrition Intervention for Healing Our Children

http://www.noamalgam.com/biologicaltreatments.html

Biological Treatments for Autism and PDD

>

> I just got this post from the autism action plan group and thought Id post

here for any one interested.

>

> Karla

>

> -- The following message was posted by Kurt Woeller (DrKurtWoeller) in the

" Other Therapies " category. All replies to this e-mail will be sent to the

group --

>

> For those of you interested in Dr. Haley's response regarding OSR and its 1/2

life. I did receive an email back from Dr. Haley. Here was his response:

>

> * " OSR has a plasma and organ half-life of 6 to 7 hours in test animals (rats).

It peaks at 2 hours after ingestion in the plasma and all organs we tested

(brain, kidney, liver, intestines, bone marrow, epidermal and internal fat

tissues). At 24 hours after ingestion the plasma and organ levels are down to

4-12% of the peak values at 2 hours. I have taken OSR three times daily for over

a year, early morning, noon and evening based on the 6-7 hour plasma half life.

My health analysis is excellent, I have no build up of OSR, no loss of essential

minerals (we checked this out long ago), and I feel quite healthy. I have been

taking OSR 3 ½ years. My blood glutathione is 1580 whereas the average is 669,

so I am in good shape with regards to this oxidative stress marker----and I had

no signs of any other oxidative stress markers at my last physical. This

information has been on our website for quite a long time. I think the comments

of Dr. Cutler are quite old and keep being brought up by those that may not want

OSR to be used. "

> *

>

> I hope this helps,

>

> Dr. Woeller

>

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Someone kindly pointed out that I didn't read this carefully enough when I made

my prior reply. I replied as if it was from Dr. Woeller, this actually is Dr.

Haley's response.

> For those of you interested in Dr. Haley's response regarding OSR and its 1/2

life. I did receive an email back from Dr. Haley. Here was his response:

>

> * " OSR has a plasma and organ half-life of 6 to 7 hours in test animals (rats).

In a dozen of them, in one experiment, by one investigator who hasn't published

the results.

This really is not good enough information to assert a half life in humans.

There should be both replication of the rat studies by other investigators,

publication of all studies or at least presentation in a form similarly detailed

to what one would use in publication, and at least some measurements in actual

human beings, e. g. blood concentrations at 2 and 8 hours after oral ingestion

in a dozen people.

>It peaks at 2 hours after ingestion in the plasma and all organs we tested

(brain, kidney, liver, intestines, bone marrow, epidermal and internal fat

tissues). At 24 hours after ingestion the plasma and organ levels are down to

4-12% of the peak values at 2 hours.

Simply repeating information provided earlier does not advance the argument.

Generally what Dr. Haley is doing here is to avoid the progressive flow of

thought that constitutes argument in favor of just repeating information already

shown to be flawed.

For progress in understanding to be made, those arguing really need to be

ethical and respond to each other's reasoning point by point, moving the

argument forward until they can reach some points of agreement rather than just

continually reiterating the same point so as to avoid the possiblity of

conceding anything.

>I have taken OSR three times daily for over a year, early morning, noon and

evening based on the 6-7 hour plasma half life. My health analysis is excellent,

I have no build up of OSR, no loss of essential minerals (we checked this out

long ago), and I feel quite healthy. I have been taking OSR 3 ½ years. My blood

glutathione is 1580 whereas the average is 669, so I am in good shape with

regards to this oxidative stress marker----and I had no signs of any other

oxidative stress markers at my last physical.

I admire Dr. Haley's fortitude in choosing to be the first human test subject.

However there is a long history of horrible catastrophes due to release of drugs

where the investigators used themselves as test subjects rather than relying on

a large enough group selected to represent the population who actually would use

the stuff. E. g. thalidomide, heroin.

Information on a couple of dozen more human subjects, including measurement of

OSR blood levels for kinetics, would be very much more convincing.

Also a technical note: OSR is the type of compound that will be an interference

in most assays for glutathione. I'd like to know the details of the assay and

how they are sure the result truly represents glutathione, rather than

(glutathione + OSR).

>This information has been on our website for quite a long time. I think the

comments of Dr. Cutler are quite old and keep being brought up by those that may

not want OSR to be used. "

This is a nice rhetorical device. Dr. Haley admits the information he is

presenting is old (saying it has been on their website for quite a long time)

then accuses me of using " old information, " as if that was relevant.

It doesn't matter if the information is old or new, accuracy is what counts. I

presented accurate information that I believe shows it is not ethical to sell or

prescribe or dispense OSR for many reasons, Dr. Haley has not rebutted or even

addressed any of it. Dr. Haley in his prior communication stated he had no

special expertise regarding chelation (and made it clear that was true). Take

it from someone who DOES have special expertise regarding chelation, there is

not enough information to have any reasonable likelihood of understanding how to

use OSR safely. In my opinion it is not ethical to sell it, prescribe it,

dispense it, or encourage people to use it outside the context of a situation

where they understand they are taking essentially the same risks as someone in a

phase 1 or 2 clinical trial of an experimental new drug.

I understand that ethics involves personal values and opinions may differ on

this, but I find it truly shocking they differ so profoundly in this case. But

then I also find it truly shocking that most physicians continue to administer

mercury laden vaccines to infants even today (e. g. the H1N1 flu shot, which the

health departments made a special exception for even in states like Washington

that legally prohibit the use of mercury preserved vaccines in children).

Obviously, reasoning is not working in conveying my legitimate (and correct)

technical concerns to Dr. Haley and DAN! doctors - they aren't taking any

actions to address these concerns, or to control risks from the unknown factors

that motivate these concerns. If anyone else has a better idea of how to

convince them, please go for it!

Andy

PS, the original interaction between Dr. Haley and myself is reproduced below

for your reference.

++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++

A message purported to be Boyd Haley's response to me is circulating on the

internet. I believe it is appropriate for me to respond to it with some further

useful information. I have cut my responses into this message, and also

appended the message in full at the end of the `discussion' so there can be no

question I have not taken it out of context in any way. It is of course

possible, given the joys of digital communications, that this message has been

forwarded many times and may have been modified so that it does not accurately

convey Dr. Haley's views, or may not have been intended as anything other than a

private message to a single specific recipient (and may thus have been imprecise

and not well wordsmithed for completely reasonable reasons). However all I can

do is respond to it as is and if there have been any modifications or statements

not accurately conveying Dr. Haley's thoughts I hope he will feel free to

correct those. I'll be forwarding him a courtesy copy of this privately, and

to Dr. Flatabø if I can find a valid email address for him, as well as

circulating it publicly.

Anyone who wishes may forward this or repost it provided that the entire

message, without any modification is posted and any additional commentary is

clearly identified as such and ONLY appears at the beginning of the message.

++++++++++++++++++++++++++++++++++++++++++++++++++++++

Dr. Haley's original message (preceded by > >) with my comments

++++++++++++++++++++++++++++++++++++++++++++++++++++++

>

>

> Boyd Haleys Response to Andy Cutlers " message "

>

> Geir Flatabø

>

>

> > First, the only claim made for OSR is that it is a lipid soluble, dietary

> > antioxidant that scavenges free radicals and helps maintain a healthy

> > glutathione level. Maintaining a healthy glutathione level can possibly

> > help detox the body of any toxin that is carried out of the body as a

> > glutathione complex, and this includes many heavy metals as well as toxic

> > organic molecules that are attached to glutathione by the enzyme

> > glutathione-S-transferase after the oxidation by the Phase II P-450

> > enzymes.

> >

> >

> >

> > I know of Andy Cutler and have read his book and I agree that he has

> > proposed a detox scheme involving LPA (lipoic acid) that I have found quite

> > reasonable as I am also not a fan of using toxic chelators. However, this

> > detox scheme has not effectively reversed the oxidative stress (as measured

> > by low reduced glutathione levels) in many who have tried it, or so I am

> > told. This may be due to the fact that LPA ( has a disulfide linkage and

> > already in the oxidized form and unable to bind any metal in its delivered

> > form) can add to the oxidized stress level as LPA (lipoic acid) has to be

> > reduced to the dihydrolipoic acid (dihydro-LPA) form before it can bind to

> > any metal. This reduction of LPA to dihydro-LPA requires reducing

> > potential and reduces the body's ability to produce reduced glutathione

> > since both the reduction of oxidized LPA and oxidized Glutathione (GSSG) are

> > biochemical steps that consume reducing equivalents in the form of the basic

> > molecule(s) NAD(P)H. Using a beginning oxidized molecule to treat

> > patients who are already under oxidative stress is not the best approach in

> > my opinion. One big difference between OSR and LPA is one is totally in

> > the reduced form (OSR) and one is in the oxidized form (LPA). Another

> > difference is OSR is without a charge and LPA has a negatively charged acid

> > group on it, this likely could change the partitioning in the cell membrane

> > and fatty tissues. Further, google " lipoic acid MSDS " and the material

> > safety data sheet will give you a LD-50 value, do the same with vitamin E.

> > We could not determine a LD-50 of OSR and the group that tested its safety

> > stated the LD-50 is above 5 grams/kg body weight. Just because something

> > is natural does not mean it is safe.

> >

> >

> >

> > Also, Andy makes some comments about me that are just not true. I have

> > taught graduate level biochemistry/physiology courses since 1974,

> > specializing in biochemical kinetics/thermodynamics and bioenergetics. My

> > area of research expertise for over 30 years was to use novel, chemically

> > synthesized compounds to unravel problems in energy utilizing enzymes and

> > pathways. Without hopefully sounding like a braggart, I was quite

> > successful. I certainly do understand chemical and biochemical

> > kinetics/thermodynamics and how certain compounds pass through the membranes

> > and organs of mammals. I have had a huge amount of NIH funds over many

> > years to study such phenomenon and sat on NIH Study Section Panels for many

> > years helping evaluate federal grants. My past training and experience

> > has played a major role in my research success.

> >

> >

> >

> > No one in medicine totally understands all of the intricacies required for

> > heavy metal detox or movement of chemicals around the body and I am not

> > claiming exceptional knowledge. I just claim to be a solid, well trained

> > scientist that knows how to design and test certain compounds to accomplish

> > specific goals and how to test them to make sure they are as safe as one can

> > possibly predetermine them to be. I then know enough to proceed slow and

> > easy with the help of other well trained associates doing the monitoring

> > until maximum safety and efficiency is established or not. What bothers

> > me about Andy Cutler's article is that he judges my work but does not know

> > what I have done, or what I can disclose and cannot disclose and still be of

> > immediate help to many. He is interpreting going slow and doing careful

> > work as not having done essential studies and this is not the case.

Initially,

> > the compound was not offered to anyone except those who were capable of

> > testing it slowly and carefully. Andy's concerns as mentioned in his

> > missive are those that any careful person would test for, and we did, with

> > safety being the highest priority. I can also assure you that the DAN

> > doctors couldn't have been more cautious in regards to evaluating OSR and it

> > is today not a " DAN " approved procedure. We recently just started and

> > much work was done before any OSR was provided to anyone.

> >

> >

> >

> > In the recent past we have obtained pharmacokinetic studies on OSR, data on

> > OSR's oxygen radical absorbance capacity and identification of the

> > metabolites of OSR in human liver homogenates. We know that OSR peaks in

> > the plasma and all tested organs after two hours post ingestion, at 24 hours

> > post ingestion the levels are between 4 to 12% of the two hour peak values.

> > OSR was found to enter the cells of all tissues tested, and to be excreted,

> > most likely as an oxidized species as indicted by the mass spectrometry data

> > obtained with liver homogenates. This study indicated that the first two

> > main products of OSR modification by liver homogenates were those with 2 and

> > 3 oxygens attached to the arm with the sulfhydryl attached as would be

> > expected for a free radical scavenger.

> >

> >

> >

> > OSR did not concentrate in the brain and was effectively excreted from this

> > organ. While I cannot assure one of the mechanism it is well known that

> > most compounds taken into the body are excreted by mechanisms that protect

> > the brain from excess exposure. I think the same is true of OSR, it is

> > obviously being excreted by a mechanism that is designed to removed

> > compounds with oxidized sulfhydryls. Do note the similarity of the

> > sulfhydryl containing arms of OSR to that of reduced glutathione. This

> > was put in the design of OSR on purpose to take advantage of any

> > characteristic that would allow additional safety and utility.

> >

> >

> >

> > Finally, Andy's comments about LPA being a superior binding agent because

> > it forms a six membered ring is seriously flawed, the affinity of binding

> > any specific metal depends a lot on the angle of binding that specific

> > (coordination chemistry) and a six membered ring is only considered the most

> > stable or sterically favored if the angle is that of a carbon atom, not any

> > metal. For example, the most stable bond angle of the two bonds of Hg2+

> > is 180o, consider that there is no way a 180o bond angle can be formed

> > with Hg2+ in a six membered ring consisting of 5 carbons as found in

> > dihydro-LPA.

> >

> >

> >

> > Boyd E. Haley, PhD

Andy

http://www.noamalgam.com/index.html

Amalgam Illness: Diagnosis and Treatment

http://www.noamalgam.com/hairtestbook.html

Hair Test Interpretation: Finding Hidden Toxicities

http://www.noamalgam.com/nourishinghope.html

Nourishing Hope for Autism: Nutrition Intervention for Healing Our Children

http://www.noamalgam.com/biologicaltreatments.html

Biological Treatments for Autism and PDD

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Talk about a passion for getting to the truth of the matter, (of Understanding,

for our selves?) and for exposing slights of deception, otherwise? .. . Dr.

Cutler, (Andy?) you only have to point out that what the other is saying

(whoever?) isn't properly validated... with what you're doing with respect to

the voluntary/ communication/ ethical thing? (!) of making sense as you do, for

as much, I'd be Feeling.. .

You simply ! (of so much to simplify, no doubt) That's pretty much the essence

of It! I Feel (of what I Feel we should be doing of one of the dimensions of

Understanding More? if not life..) which I realize the other wouldn't like to

see you get away with, of the/thier problem? somewhat? (no doubt) so easily, of

their self-serving (if not delusional) obfuscating BS? .. . that I need wishful

thinking (guinea-pig expectations?) or hope (inspiration?) like that, if you

know what *I* mean, but I suspect you do.. . (The fine *analyst* you are

I see little in what you're saying and doing (of saying?!.) that doesn't make

sense, of all that I've read, (of your example!) but I'm not of the view that I

*have* to, read everything you've said, to understand as much... of you, of

Everything, so True (of such game if not abuse if not knowledge, otherwise.. .

I find there is really no lie to any part of the truth!

Thanks for sharing (and caring) as much as you do

Best wishes, Thereof

Mike Glavic

I'll stay away from OSR whatever it is.. .

> >

> > Boyd Haleys Response to Andy Cutlers " message "

> >

> > Geir Flatabø

> >

> >

> > > First, the only claim made for OSR is that it is a lipid soluble, dietary

> > > antioxidant that scavenges free radicals and helps maintain a healthy

> > > glutathione level. Maintaining a healthy glutathione level can possibly

> > > help detox the body of any toxin that is carried out of the body as a

> > > glutathione complex, and this includes many heavy metals as well as toxic

> > > organic molecules that are attached to glutathione by the enzyme

> > > glutathione-S-transferase after the oxidation by the Phase II P-450

> > > enzymes.

> > >

> > >

> > >

> > > I know of Andy Cutler and have read his book and I agree that he has

> > > proposed a detox scheme involving LPA (lipoic acid) that I have found

quite

> > > reasonable as I am also not a fan of using toxic chelators. However, this

> > > detox scheme has not effectively reversed the oxidative stress (as

measured

> > > by low reduced glutathione levels) in many who have tried it, or so I am

> > > told. This may be due to the fact that LPA ( has a disulfide linkage and

> > > already in the oxidized form and unable to bind any metal in its delivered

> > > form) can add to the oxidized stress level as LPA (lipoic acid) has to be

> > > reduced to the dihydrolipoic acid (dihydro-LPA) form before it can bind to

> > > any metal. This reduction of LPA to dihydro-LPA requires reducing

> > > potential and reduces the body's ability to produce reduced glutathione

> > > since both the reduction of oxidized LPA and oxidized Glutathione (GSSG)

are

> > > biochemical steps that consume reducing equivalents in the form of the

basic

> > > molecule(s) NAD(P)H. Using a beginning oxidized molecule to treat

> > > patients who are already under oxidative stress is not the best approach

in

> > > my opinion. One big difference between OSR and LPA is one is totally in

> > > the reduced form (OSR) and one is in the oxidized form (LPA). Another

> > > difference is OSR is without a charge and LPA has a negatively charged

acid

> > > group on it, this likely could change the partitioning in the cell

membrane

> > > and fatty tissues. Further, google " lipoic acid MSDS " and the material

> > > safety data sheet will give you a LD-50 value, do the same with vitamin E.

> > > We could not determine a LD-50 of OSR and the group that tested its safety

> > > stated the LD-50 is above 5 grams/kg body weight. Just because something

> > > is natural does not mean it is safe.

> > >

> > >

> > >

> > > Also, Andy makes some comments about me that are just not true. I have

> > > taught graduate level biochemistry/physiology courses since 1974,

> > > specializing in biochemical kinetics/thermodynamics and bioenergetics. My

> > > area of research expertise for over 30 years was to use novel, chemically

> > > synthesized compounds to unravel problems in energy utilizing enzymes and

> > > pathways. Without hopefully sounding like a braggart, I was quite

> > > successful. I certainly do understand chemical and biochemical

> > > kinetics/thermodynamics and how certain compounds pass through the

membranes

> > > and organs of mammals. I have had a huge amount of NIH funds over many

> > > years to study such phenomenon and sat on NIH Study Section Panels for

many

> > > years helping evaluate federal grants. My past training and experience

> > > has played a major role in my research success.

> > >

> > >

> > >

> > > No one in medicine totally understands all of the intricacies required for

> > > heavy metal detox or movement of chemicals around the body and I am not

> > > claiming exceptional knowledge. I just claim to be a solid, well trained

> > > scientist that knows how to design and test certain compounds to

accomplish

> > > specific goals and how to test them to make sure they are as safe as one

can

> > > possibly predetermine them to be. I then know enough to proceed slow and

> > > easy with the help of other well trained associates doing the monitoring

> > > until maximum safety and efficiency is established or not. What bothers

> > > me about Andy Cutler's article is that he judges my work but does not know

> > > what I have done, or what I can disclose and cannot disclose and still be

of

> > > immediate help to many. He is interpreting going slow and doing careful

> > > work as not having done essential studies and this is not the case.

Initially,

> > > the compound was not offered to anyone except those who were capable of

> > > testing it slowly and carefully. Andy's concerns as mentioned in his

> > > missive are those that any careful person would test for, and we did, with

> > > safety being the highest priority. I can also assure you that the DAN

> > > doctors couldn't have been more cautious in regards to evaluating OSR and

it

> > > is today not a " DAN " approved procedure. We recently just started and

> > > much work was done before any OSR was provided to anyone.

> > >

> > >

> > >

> > > In the recent past we have obtained pharmacokinetic studies on OSR, data

on

> > > OSR's oxygen radical absorbance capacity and identification of the

> > > metabolites of OSR in human liver homogenates. We know that OSR peaks in

> > > the plasma and all tested organs after two hours post ingestion, at 24

hours

> > > post ingestion the levels are between 4 to 12% of the two hour peak

values.

> > > OSR was found to enter the cells of all tissues tested, and to be

excreted,

> > > most likely as an oxidized species as indicted by the mass spectrometry

data

> > > obtained with liver homogenates. This study indicated that the first two

> > > main products of OSR modification by liver homogenates were those with 2

and

> > > 3 oxygens attached to the arm with the sulfhydryl attached as would be

> > > expected for a free radical scavenger.

> > >

> > >

> > >

> > > OSR did not concentrate in the brain and was effectively excreted from

this

> > > organ. While I cannot assure one of the mechanism it is well known that

> > > most compounds taken into the body are excreted by mechanisms that protect

> > > the brain from excess exposure. I think the same is true of OSR, it is

> > > obviously being excreted by a mechanism that is designed to removed

> > > compounds with oxidized sulfhydryls. Do note the similarity of the

> > > sulfhydryl containing arms of OSR to that of reduced glutathione. This

> > > was put in the design of OSR on purpose to take advantage of any

> > > characteristic that would allow additional safety and utility.

> > >

> > >

> > >

> > > Finally, Andy's comments about LPA being a superior binding agent because

> > > it forms a six membered ring is seriously flawed, the affinity of binding

> > > any specific metal depends a lot on the angle of binding that specific

> > > (coordination chemistry) and a six membered ring is only considered the

most

> > > stable or sterically favored if the angle is that of a carbon atom, not

any

> > > metal. For example, the most stable bond angle of the two bonds of Hg2+

> > > is 180o, consider that there is no way a 180o bond angle can be formed

> > > with Hg2+ in a six membered ring consisting of 5 carbons as found in

> > > dihydro-LPA.

> > >

> > >

> > >

> > > Boyd E. Haley, PhD

>

>

> Andy

>

> http://www.noamalgam.com/index.html

> Amalgam Illness: Diagnosis and Treatment

>

> http://www.noamalgam.com/hairtestbook.html

> Hair Test Interpretation: Finding Hidden Toxicities

>

> http://www.noamalgam.com/nourishinghope.html

> Nourishing Hope for Autism: Nutrition Intervention for Healing Our Children

>

> http://www.noamalgam.com/biologicaltreatments.html

> Biological Treatments for Autism and PDD

>

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