ANDY/Help! please read this pubmed publication /white lesions on brain

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My son's MRI showed up with white lesions.He has major regression.Is this

article suggesting that chelation was respinsible or resolved the

issue????jakob's mom thank u for ur help!

Hyperintense lesions in brain MRI after exposure to a mercuric

chloride-containing skin whitening cream.

Benz MR, Lee SH, Kellner L, Döhlemann C, Berweck S.

Dr. von Haunersches Kinderspital, University Children's Hospital,

Ludwigs-Maximilians-University, Munich, Lindwurmstrasse 4, 80337, Munich,

Germany, Marcus.Benz@....

Abstract

Exposure to inorganic mercury (Hg) is a serious problem presenting with a

combination of neurological and psychiatric symptoms along with weight loss,

pruritus, erythema, arterial hypertension, tachycardia, and renal tubular

dysfunction. We report a 4-year-old girl with chronic intoxication of inorganic

mercury secondary to the accidental use of an Hg(2)Cl(2)- and HgCl(2)-containing

skin whitening cream (urine level of Hg, 41.1 & #956;g/l; reference level, <25

& #956;g/l). Under treatment with dimercapto-1-propansulficacid, Hg level in the

urine raised to 1,175.5 & #956;g/l, neurological deterioration occurred, and

brain magnetic resonance imaging (MRI) showed on fluid attenuated inversion

recovery sequences new hyperintense lesions in the subcortical white matter.

After 4 months, clinical signs and symptoms and brain MRI findings resolved.

This is a first case of inorganic mercury poisoning showing hyperintense lesions

in brain MRI and confirms earlier cases showing transient deterioration during

chelation therapy. Although urinary excretion could be enhanced during chelation

therapy, signs and symptoms of intoxication could be worsened.

PMID: 21052738 [PubMed - as supplied by publisher]