Where did you get the info @ abx and our bodies

[Guest guest]

Connie, Where did you get this information? I would love to share this

with my LLMD. Is oral antibiotics for a long time (years) more of a problem

than the IV therapy over 4-6 or more months with follow-up on oral? Does

anyone know? I would prefer research, doctor information, websites, etc. for

verification. Thanks for the help! KC in TX

Re: [ ] abx and our bodies

> Hi Everyone,

> I too think we need to be very careful with abx.......and the damage it

can

> also cause to our bodies.............the lyme bacteria and the abx cause

> major damage to our bodies..........unfortunately.

> Connie nwnj

> Leave no stone unturned.......and ask questions!

>

>

>

>

[Guest guest]

Hi ,

IV many times is a must in treating this disease......8 months of it put me

into remission...........ABX is NEEDED TO TREAT THIS disease..........but

you need to check Liver enzymes and protect yourself..take

supplements......watch for abnormal developments in your body...don't

attribute every symptom to Lyme disease.......If I did that I would still be

on damaging abx.......I held off going back on abx........ I have since

found out I have a sleep disorder perhaps brought on my Lyme.......but also

exits on both sides of my family....

When you can............get off abx........so the body can help

repair...........also your body will go through abx detox......mine

did.........I thought I was herxing and ready to go back on abx.......but

held off.....Thank goodness I did............I'm symptom free, sleeping, and

feeling like myself again........!!

Remember abx is in our food too!!!!!!!!!!!!!!!!

I A NOT AGAINST ABX !!!!!!..........I did six years worth on and

off..........allowing my body to recover........at times..........All I'm am

saying is listen to your body, go with your gut.........and take

precautions, like supplements, and breaks of abx.

Your immune system is being damaged by spirochete and abx!!!

Connie nwnj

----------------------------------------------------

http://www.umich.edu/~newsinfo/Releases/2001/Feb01/r021701.html

Rx for drug toxicity

SAN FRANCISCO---You say the antibiotic that cured your best friend's bladder

infection made you break out in a full body rash? And the hormone therapy

they used to shrink your father's prostate cancer made it grow instead? And

the only drug that ever helped your irritable bowel syndrome was just taken

off the market, because five people died from its side effects?

---------------------------------------------------

http://www.md.ucl.ac.be/entites/farm/facm/cellular_toxicity.htm

Cellular toxicity of antibiotics and other drugs

Senior Investigators: M.P. Mingeot-Leclercq; F. Van Bambeke,

Doctoral fellow (PhD student): D. Tyteca (1996-); H. Servais (1999-)

Non-doctoral fellow (student in nutrition): Miabandu Nyindu (1999-)

View of the mode of assembly of the protonated form of azithromycin (ball

representation) with phosphatidylinositol (skeleton; the polar heads of the

phospholipid are towards the bottom of the picture, and the lipid domain

[fatty acid chains] extend towards the top of the figure). The two atoms in

blue in the drug molecule are the two ionizable nitrogens (in the desosamine

[position 3'] and in the macrocyle [endocyclic nitrogen in position 9a]. As

the model shows, azithromycin deeply penetrates into the monolayer, the 3'

nitrogen atom being parly schielded by the two methyl groups (tertiary

amine). The construction of virtual molecules in which these methyl groups

are removed causes indeed a complete change of orientation by increasing the

global polarity of the desosamine.

From Montenez et. al., 1996, Eur. J. Pharmacol. 314:215-227.

----------------------------------------------------

J Clin Epidemiol 1994 Oct;47(10):1203-10 Related Articles, Books

A case-control study of drugs and other determinants as potential causes of

Guillain-Barre syndrome.

Stricker BH, van der Klauw MM, Ottervanger JP, van der Meche FG.

Netherlands Center for Monitoring of Adverse Reactions to Drugs, Rijswijk.

The Guillain-Barre syndrome is an inflammatory demyelinating polyneuropathy

with an acute or subacute onset. The current case-control study was

performed to investigate the possible role of drugs and other determinants

in the causation of the Guillain-Barre syndrome. Patients were included as

cases if they fulfilled the criteria for acute Guillain-Barre syndrome and

were unable to walk 10 m independently and had been admitted to the hospital

within 2 weeks of onset of the neuropathy. For every case, two controls

without the disease were obtained from the general practitioner (GP) of the

patient with Guillain-Barre syndrome. Controls had the same type of health

care insurance, were of the same gender and age (within 5 years), and

resident in the same area. By telephone, the GPs of the patients with

Guillain-Barre syndrome were interviewed. There were 71 female and 75 male

cases and 142 female and 149 male controls. Significantly more cases than

controls had been prescribed drugs in the 3 months prior to the index date

and also diagnoses or symptoms in cases were more common. Case patients used

significantly more frequently antipropulsives (loperamide), penicillins

(amoxicillin with or without clavulanic acid) and vaccines. Female controls

used significantly more often oral contraceptives. More cases than controls

suffered from infections of the respiratory, gastrointestinal or urinary

tract prior to the onset of neurological symptoms. In a logistic regression

analysis, symptoms concerning the gastrointestinal and respiratory system

were strongly associated with the Guillain-Barre syndrome. The use of oral

contraceptives was significantly lower in female cases which could be

compatible with the hypothesis that these drugs are protective.

---------------------------------------------------

http://www.sciam.com/1998/0398issue/0398levy.html

Widespread use of cephalosporin antibiotics, for example, has promoted the

proliferation of the once benign intestinal bacterium E. faecalis, which is

naturally resistant to those drugs. In most people, the immune system is

able to check the growth of even multidrug-resistant E. faecalis, so that it

does not produce illness. But in hospitalized patients with compromised

immunity, the enterococcus can spread to the heart valves and other organs

and establish deadly systemic disease.

Moreover, administration of vancomycin over the years has turned E. faecalis

into a dangerous reservoir of vancomycin-resistance traits. Recall that some

strains of the pathogen S. aureus are multidrug-resistant and are responsive

only to vancomycin. Because vancomycin-resistant E. faecalis has become

quite common, public health experts fear that it will soon deliver strong

vancomycin resistance to those S. aureus strains, making them incurable.

The bystander effect has also enabled multidrug-resistant strains of

Acinetobacter and Xanthomonas to emerge and become agents of potentially

fatal blood-borne infections in hospitalized patients. These formerly

innocuous microbes were virtually unheard of just five years ago.

As I noted earlier, antibiotics affect the mix of resistant and nonresistant

bacteria both in the individual being treated and in the environment. When

resistant bacteria arise in treated individuals, these microbes, like other

bacteria, spread readily to the surrounds and to new hosts. Investigators

have shown that when one member of a household chronically takes an

antibiotic to treat acne, the concentration of antibiotic-resistant bacteria

on the skin of family members rises. Similarly, heavy use of antibiotics in

such settings as hospitals, day care centers and farms (where the drugs are

often given to livestock for nonmedicinal purposes) increases the levels of

resistant bacteria in people and other organisms who are not being

treated--including in individuals who live near those epicenters of high

consumption or who pass through the centers.

----------------------------------------------------

http://www.internethealthlibrary.com/Health-problems/Cervical%20Cancer%20-%2

0researchDiet & Lifestyle.htm

Meat & Cervical Cancer

There are countless studies revealing that meat (ie. red meats and poultry)

are related to all forms of cancers. (9) For instance a 25 year study

conducted in Israel found that as the consumption of animal fat increased,

so too did the rate of cancer deaths(10). Another study in Hawaii

specifically mentions cancer of the uterus and found that there was a

positive correlation with consumption of animal fat and animal protein

(11).Interestingly, many studies are indicating that a vegetarian diet helps

protect against all forms of cancer beause vegetarian populations have lower

rates of common cancer and meat consumption is positively linked to the

incidence and mortality of cancer (see also protective value of vegetables

above). Some of the explanations being offered include the conditions the

animals are reared in intensive farms and the proliferate use of hormones

and antibiotics used in the meat industry. However, many physiologists agree

that humans are not, by nature omnivores but rather herbivores like other

primates and the levels of fat and protein in meat is not conducive to good

health.

---------------------------------------------------

http://www.findarticles.com/cf_dls/g2601/0000/2601000092/p1/article.jhtml

Although all antibiotics can cause this disease, it is most commonly caused

by clindamycin (Cleocin), ampicillin (Omnipen), amoxicillin (Amoxil,

Augmentin, or Wymox), and any in the cephalosporin class (such as cefazolin

or cephalexin). Symptoms of the condition can occur during antibiotic

treatment or within four weeks after the treatment has stopped.

---------------------------------------------------

http://www.umich.edu/~newsinfo/Releases/1997/Oct97/r100697b.html

Discovered in the 1940s, these antibiotics---which include streptomycin,

gentamicin, neomycin and others---are the most widely used antibiotics in

the world. Because they are so effective and rarely produce allergic

reactions, physicians continue to prescribe them, even though they are known

to cause hearing loss and kidney damage in a significant percentage of

individuals who take them. " In the United States, aminoglycosides are most

often used for emergency treatment of people with serious infections who

have not responded to other types of antibiotics, " said Jochen Schacht, a

professor of biological chemistry and otolaryngology in the U-M Medical

School. " Increasing levels of antibiotic-resistant infections associated

with AIDS and a worldwide resurgence of tuberculosis, however, make it

likely that their use will increase in the future.

-------------------------------------------------

http://www.factmonster.com/ce6/sci/A0856637.html

Antibiotics are either injected, given orally, or applied to the skin in

ointment form. Many, while potent anti-infective agents, also cause toxic

side effects. Some, like penicillin, are highly allergenic and can cause

skin rashes, shock, and other manifestations of allergic sensitivity.

Others, such as the tetracyclines, cause major changes in the intestinal

bacterial population and can result in superinfection by fungi and other

microorganisms. Chloramphenicol, which is now restricted in use, produces

severe blood diseases, and use of streptomycin can result in ear and kidney

damage. Many antibiotics are less effective than formerly because

antibiotic-resistant strains of microorganisms have emerged (see drug

resistance).

-----------------------------------------------

http://www.canoe.com/Health0005/25_ecoli.html

They theorized that antibiotics cause the release of toxins from the

bacteria into the intestine.

The E.coli bacteria also causes thousands of cases of food poisoning in

North America annually. The infection often spreads through eating

undercooked contaminated meat and typically causes bloody diarrhea.

The infection spreads throughout the body, said Matsell.

It affects the small blood vessels and can affect the brain, kidneys and

blood. It can also cause small clots, like mini strokes.

There is hope for those who get treatment.

" The kidney can repair itself. (But) there's not many things (that) can or

do alter the course of the disease. "

----------------------------------------------------

http://www.gihealth.com/TREC2/articles/cdifficile.html

Good Versus Evil

The problem is one of imbalance. The digestive tract is sterile at birth.

Within a few hours, bacteria from the environment enter the intestines.

Within a few weeks, these bacterial are well established and are present for

life. The colon, or large intestine, normally contains trillions of bacteria

that live and multiply happily within the colon. In fact, there are more

intestinal bacteria in your colon at this moment than there are human beings

who have ever lived. In fact, an average adults harbors more than 400

distinct species of bacteria. Most of these are considered " healthy

bacteria. " They do not bother you and you don't bother them. All is in

balance. A small percentage of these bacteria are harmful - but they are

kept in check by all of the healthy bacteria.

----------------------------------------------------

http://www.drweil.com/archiveqa/0,2283,184,00.html

(Published 2/6/97) A round of antibiotics is a logical treatment for your

condition. An organism called Borrelia burgdorferi, which is carried by deer

ticks, causes Lyme disease. The disease is poorly understood, but it's

usually treated by up to one month of antibiotics. These should eradicate

the organism if they're administered at the right time.

You're right, though, to be cautious about the side effects of antibiotics.

Along with the harmful invaders, antibiotics also destroy the beneficial

flora in your gut, and can encourage problems like the development of

resistant organisms in your body.

---------------------------------------------------

: Clin Infect Dis 1997 May;24(5):958-64 Related Articles, Books

Relationship of adverse events to serum drug levels in patients receiving

high-dose azithromycin for mycobacterial lung disease.

Brown BA, Griffith DE, Girard W, Levin J, Wallace RJ Jr.

Department of Microbiology, The University of Texas Health Center at Tyler,

75710, USA.

We treated 39 elderly human immunodeficiency virus-noninfected patients with

Mycobacterium avium complex and/or Mycobacterium abscessus lung disease with

azithromycin (600 mg daily), given initially as monotherapy. Adverse events

occurred in 33 of 39 patients (85%) receiving azithromycin alone, most

commonly gastrointestinal (GI) symptoms (32 of 39, or 82%) and hearing

impairment (10 of 39, or 26%). Twenty-four of 39 patients (62%) required a

lower dose or withdrawal of the drug. The mean serum level in patients who

required a dose reduction because of hearing impairment was 0.8 +/- 0.4

microg/mL, and that in patients whose reduction was necessitated by GI

symptoms was 0.7 +/- 0.4 microg/mL; in comparison, the mean serum level was

0.3 +/- 0.16 microg/mL in patients with no adverse events (P = .004 and

..003, respectively). Decreasing the daily dose to 300 mg resulted in

resolution of most adverse events. Serum levels with monotherapy were

comparable to levels after the addition of other antituberculous drugs that

included rifampin or rifabutin. Thus, a 300-mg rather than 600-mg daily dose

of azithromycin is better tolerated by elderly patients, and serum levels

appear unaffected by other antituberculous agents, including rifampin.

--------------------------------------------------

Rev Infect Dis 1982 Sep-Oct;4 Suppl:S481-8 Related Articles, Books

Cefotaxime and cephalosporins: adverse reactions in perspective.

CR.

Cefotaxime was used to treat infections in 2,579 patients during phase II

and phase III clinical trials. This paper summarizes the adverse reactions

reported to Hoechst-Roussel Pharmaceuticals (Somerville, NJ) during the

treatment of these infections. Cefotaxime caused adverse reactions that are

caused by all other cephalosporins, including pain at the site of injection

(31.9%), thrombophlebitis (4.9%), skin rash (1.8%), thrombocytopenia (3.8%),

glomerulotubular dysfunction (1.4%), diarrhea (1.2%), and superinfection

(1.1%). Compared with cefazolin, cefotaxime caused pain on injection,

phlebitis, and diarrhea more commonly (P less than 0.05) but caused

superinfection less commonly (P less than 0.04). Since these data were

obtained from many different sources by diverse methods, further controlled

trials are needed to substantiate these differences. However, the adverse

reactions caused by cefotaxime appear to be similar in spectrum and severity

to those caused by other cephalosporins.

--------------------------------------------------

: J Infect Dis 1995 Feb;171(2):356-61 Related Articles, Books, LinkOut

Biliary complications in the treatment of unsubstantiated Lyme disease.

Ettestad PJ, GL, Welbel SF, Genese CA, Spitalny KC, Marchetti CM,

Dennis DT.

Bacterial Zoonoses Branch, Centers for Disease Control and Prevention (CDC),

Fort , Colorado.

Treatment of unsubstantiated Lyme disease has led to serious complications

in some cases. Two case-control studies, based on information in clinical

records of patients discharged with a diagnosis of Lyme disease during

1990-1992, were conducted at a central New Jersey hospital. Twenty-five

patients with biliary disease were identified, and 52 controls were selected

from 1352 patients with suspected Lyme disease. Only 3% of 71 evaluatable

subjects met the study criteria for disseminated Lyme disease. Patients with

biliary disease were more likely than were antibiotic controls to have

received ceftriaxone and more likely than ceftriaxone controls to have

received a daily ceftriaxone dose > or = 40 mg/kg and to be < or = 18 years

old. Fourteen of 25 biliary case-patients underwent cholecystectomy; all had

histopathologic evidence of cholecystitis and 12 had gallstones. Thus,

treatment of unsubstantiated diagnoses of Lyme disease is associated with

biliary complications.

----------------------------------------------------[Ceftriaxone-induced

cholelithiasis--a harmless side-effect]?

Riccabona M, Kerbl R, Schwinger W, Spork D, Millner M, Grubbauer HM.

Univ. Kinderklinik Graz.

43 children suffering from borreliosis, meningitis and septicemia were

treated with ceftriaxone. A six year old boy with acute jaundice due to

ceftriaxone induced cholelithiasis encouraged us to reevaluate the frequency

of ceftriaxone induced cholelithiasis and its' sequelae in children in a

prospective study. Out of 43 children (age 6.3 years, 4 months to 16 years,

male: female 25:18), 20 children (46.5%) showed sonographical evidence for

ceftriaxone induced cholelithiasis after a treatment of at least 10 days.

Two of them even had signs of intrahepatic cholestasis, 3 kids suffered from

severe abdominal pain, non of them showed serologic abnormalities. Another 5

children (11.6%) had sludge in the gallbladder without evidence for

cholelithiasis. In all patients the " pseudocholelithiasis " spontaneously

resolved within at most 2 months. We suggest a sonographical examination of

the gallbladder at the end of the ceftriaxone treatment in order to detect

cholelithiasis, which might call for further monitoring and maybe dietary

treatment.

----------------------------------------------------

Connie nwnj