Re: HLA typing

[Guest guest]

Oh Rich....I feel like you paused in the middle of disseminating a great

piece of information, leaving me to want more ;-) Where do YOU suggest

I do follow up reading on specifics with respect to HLA typing

interpretations--do you have a link to a chart ( okay I am wishful

thinking here ;-) Anyway I just sent a sample to Mayo for HLA Class I &

Class II typing due to suspect AIH and your HLA explanation was very

helpful and clear and now I understand the flagging and would now like

to know the HLA tie in via " disease and genotyping for dummies - HLA I &

II specific " literatue...A link will be just fine..Thanks so much, Carol

[Guest guest]

Carol and ,

The reason I didn't say any more about this is that I don't know any

more! LOL! I'll try to dig up some more information about the

correlation between HLA genotypes and particular disorders. I think

that Dr. Shoemaker has been breaking some new ground here, so some

of his stuff may not be published yet, but he has posted some things

on the Stealth Virus Support Group list, and I'll see what I can

pull together.

Rich

> Oh Rich....I feel like you paused in the middle of disseminating a

great

> piece of information, leaving me to want more ;-) Where do YOU

suggest

> I do follow up reading on specifics with respect to HLA typing

> interpretations--do you have a link to a chart ( okay I am wishful

> thinking here ;-) Anyway I just sent a sample to Mayo for HLA

Class I &

> Class II typing due to suspect AIH and your HLA explanation was

very

> helpful and clear and now I understand the flagging and would now

like

> to know the HLA tie in via " disease and genotyping for dummies -

HLA I &

> II specific " literatue...A link will be just fine..Thanks so much,

Carol

[Guest guest]

Dear Rick,

Don't use up your energy sourcing for me...I found the HLA info for AIH

(Autoimmune Hepatitis) after a few hours searching.....No luck finding a

concise HLA disease association chart. OT, but here is the link for AIH

HLA markers for those interested:

http://www.mayo.edu/proceedings/2001/dec/7612r2.pdf

Thanks for your help and you are officially off the research effort hook

on this one....Have a a good one. Carol

[Guest guest]

this is the way my " HLA-DR by PCR " test result looked when it came

back from LAbCOrp. I believe this should be done by them. there are

alot of HLA tests, but regardless of where you have it done, it needs

to specifically called HLA-DR by PCR. anything else will not help in

diagnosing the source of neurotoxins.

HLA by PCR

DRB1 7

DRB1 13

HLA-DQ 9

HLA-DQ 6

DRB3 52A

DRB3 -

DRB4 53

DRB4 -

DRB5 -

DRB5 -

i don't know very much aboout which results mean what, but i know

that they are put together in groups of three. you take one from

DRB1, one from DQ, and one from DRB3, DRB4 or DRB5.

For me, my triplets were:

7-9-52A and 13-6-53

both are indicative of a suceptibility to mold.

here are some more triplets that i have seen posted, but for full

interpretation they must be sent to Dr Shoemaker. this is really

based on his research alone.

Dioflagenate (ciguatera)

DRB1-4, DQ-8, DRB4-53

triplet 4-8-53

Sick Building Syndrome (mold)

DRB1-7 or 17, DQ-2, DRB3-52A

triplet 7(17)-2-52A

Coag Negative Staph

DRB1-11, DQ-7, DRB3-52B

trpilet 11-7-52B

Post Lyme Syndrome

DRB1-15, DQ-6, DRB5-51

15-6-51

there are probaly many more combos, but this is all i have seen

mention of, and please don't solely rely on me here. i really do not

have full knowledge of this information, and am probably missing some

key pieces.

thanks

bill

> > Oh Rich....I feel like you paused in the middle of disseminating

a

> great

> > piece of information, leaving me to want more ;-) Where do YOU

> suggest

> > I do follow up reading on specifics with respect to HLA typing

> > interpretations--do you have a link to a chart ( okay I am wishful

> > thinking here ;-) Anyway I just sent a sample to Mayo for HLA

> Class I &

> > Class II typing due to suspect AIH and your HLA explanation was

> very

> > helpful and clear and now I understand the flagging and would now

> like

> > to know the HLA tie in via " disease and genotyping for dummies -

> HLA I &

> > II specific " literatue...A link will be just fine..Thanks so

much,

> Carol

[Guest guest]

guess what. i was wrong about some of the numbers

Sick Building Syndrome (mold) should be 7(17)-2-53

and for me my triplets should be 13-6-52A and 7-9-53 (both also mold)

i really must impress again that i don't have the full story here on

these test results, but the stuff i am getting is from posts on the

Stealth Virus Support site.

thanks

bill

> > > Oh Rich....I feel like you paused in the middle of

disseminating

> a

> > great

> > > piece of information, leaving me to want more ;-) Where do YOU

> > suggest

> > > I do follow up reading on specifics with respect to HLA typing

> > > interpretations--do you have a link to a chart ( okay I am

wishful

> > > thinking here ;-) Anyway I just sent a sample to Mayo for HLA

> > Class I &

> > > Class II typing due to suspect AIH and your HLA explanation was

> > very

> > > helpful and clear and now I understand the flagging and would

now

> > like

> > > to know the HLA tie in via " disease and genotyping for dummies -

> > HLA I &

> > > II specific " literatue...A link will be just fine..Thanks so

> much,

> > Carol

[Guest guest]

finally

Sick Building Syndrome (mold)

7(17)-2-52A(53)

i guess there are many mold combos.

> > > > Oh Rich....I feel like you paused in the middle of

> disseminating

> > a

> > > great

> > > > piece of information, leaving me to want more ;-) Where do

YOU

> > > suggest

> > > > I do follow up reading on specifics with respect to HLA typing

> > > > interpretations--do you have a link to a chart ( okay I am

> wishful

> > > > thinking here ;-) Anyway I just sent a sample to Mayo for

HLA

> > > Class I &

> > > > Class II typing due to suspect AIH and your HLA explanation

was

> > > very

> > > > helpful and clear and now I understand the flagging and would

> now

> > > like

> > > > to know the HLA tie in via " disease and genotyping for

dummies -

>

> > > HLA I &

> > > > II specific " literatue...A link will be just fine..Thanks so

> > much,

> > > Carol

[Guest guest]

, Carol, Bill and the group

Thanks for taking me off the hook, Carol, and thanks to Bill for

posting the combinations of HLA genotypes that Dr. Shoemaker has

reported to be correlated with certain neurotoxin-mediated disorders.

I'm going to go ahead and post a list of correlations that I found

in one of my immunology books:

This is from Roitt's Essential Immunology, 10th edition, 2001, p.

366:

This table gives the disease, the HLA allele it is associated with,

and the relative risk of getting the disease if one has the allele.

I hope everyone knows that just because one has the allele, it

doesn't mean that one will get the disease. It only increases the

chance of getting it.

The asterisks indicate older nomenclature for the alleles.

Class II associated

Hashimoto's disease DR11 3.2

Primary myxedema DR17(*3) 5.7

Thyrotoxicosis (Graves) DR17(*3) 3.7

Insulin-dependent diabetes DQ8 1.4

DQ2/8 20.

DQ6 0.2

's disease (adrenal) DR17(*3) 6.3

Goodpasture's syndrome *DR2 13.1

Rheumatoid arthritis DR4 5.8

Juvenile rhematoid arthritis DR8 8.1

Sjogren's syndrome DR17(*3) 9.7

Chronic active hepatitis (autoimmune) DR17(*3) 17.9

Multiple sclerosis *DR2 *DQ6 12.

Narcolepsy DQ6 38.

Dermatitis herpetiformis DR17(*3) 56.4

Celiac disease DQ2 250.

Tuberculoid leprosy *DR2 8.1

Class I, HLA B27 associated

Ankylosing spondylitis B27 87.4

Reiter's disease B27 37.

Post-salmonella arthritis B27 29.7

Post-shigella arthritis B27 20.7

Post-yersinia arthritis B27 17.6

Post-gonococcal arthritis B27 14.0

Uveitis B27 14.6

Amyloiditis in rhematoid arthritis B27 8.2

Other Class I associations

Subacute thyroiditis B35 13.7

Psoriasis vulgaris Cw6 13.3

Idiopathic hemochromatosis A3 8.2

Myasthenia gravis B8 4.4

Rich

> Dear Rick,

> Don't use up your energy sourcing for me...I found the HLA info

for AIH

> (Autoimmune Hepatitis) after a few hours searching.....No luck

finding a

> concise HLA disease association chart. OT, but here is the link

for AIH

> HLA markers for those interested:

>

> http://www.mayo.edu/proceedings/2001/dec/7612r2.pdf

>

> Thanks for your help and you are officially off the research

effort hook

> on this one....Have a a good one. Carol

[Guest guest]

Limin, I was unable to bring up that page. I wanted to see if it

looked like my results. Reading the results is very confusing, even

if they are complete. Ritchie Shoemaker, in the back of his book Mold

Warriors, gives the instructions for reading the test. I was unable

after multiple attempts to understand his instructions. However, I

had a friend who understands it and did it for me, as well as a doc

later. The doc who ordered the test should be able to read it for

you. Its a very helpful test. I am unable to clear both molds and

lyme toxins; I'm taking CSM. It helps explain why I have been ill so

long.

Again, I would think the doc should know how to decipher the numbers,

or else he/she could contact Shoemaker. He apparently is a very

willing doc to help others. jo

>

> Hi,

>

> I did a test for HLA typing with LabCorp with an attempt to

understand if my 6-year-old autistic child has a genetic makeup that

does not detoxify Lyme toxins or neurotoxins in general. His IGeneX

Lyme Western Blot was inconclusive, but Babesia FISH, IgG to Babesia

duncani, IgG Bartonella, and IgM Ehrlichia were positive. The lab of

HLA typing came back looking funny. One of my friends told me that

the result looks incomplete to her. I have posted the result here:

http://slett.net/reports/2008-09-02-labcorp-hla-typing.png. Can

someone help me to identify which parts are missing? Anything at all

can be interpreted from the partial data? I am clueless in terms of

what to look for. Thank you very much.

>

> Limin

>

>

[Guest guest]

Jo,

Thank you for taking an interest in helping me out. I upload again my son's

HLA typing result with a different file format. Hope it works this time.

Please let me know if you are still unable to bring up the page. Thank you.

http://slett.net/reports/2008-09-02-labcorp-hla-typing.jpg

I asked my son's naturopath doctor to order this test for my son. He

usually orders for me whatever labs I request, and not necessarily

understand what the labs are for. It is good that insurance covers most of

our labs, but I need to make some efforts in understand the implication of

the labs. We just recently have our first consultation with Dr. Klinghardt,

who also does not count on labs to give diagnosis. We have not decided yet

to consult with a LLDM.

I also just added " Mold Warriors " at my Amazon.com shopping cart. Thank

you.

Limin

--------------------------------------------------

From: " judyjo27 " <judyjo44@...>

Sent: Wednesday, October 15, 2008 09:08

< >

Subject: [ ] Re: HLA typing

> Limin, I was unable to bring up that page. I wanted to see if it

> looked like my results. Reading the results is very confusing, even

> if they are complete. Ritchie Shoemaker, in the back of his book Mold

> Warriors, gives the instructions for reading the test. I was unable

> after multiple attempts to understand his instructions. However, I

> had a friend who understands it and did it for me, as well as a doc

> later. The doc who ordered the test should be able to read it for

> you. Its a very helpful test. I am unable to clear both molds and

> lyme toxins; I'm taking CSM. It helps explain why I have been ill so

> long.

>

> Again, I would think the doc should know how to decipher the numbers,

> or else he/she could contact Shoemaker. He apparently is a very

> willing doc to help others. jo

>

>

[Guest guest]

Please e-mail me. jjohnsonnd@...

[ ] HLA typing

Hi,

I did a test for HLA typing with LabCorp with an attempt to understand if my

6-year-old autistic child has a genetic makeup that does not detoxify Lyme

toxins or neurotoxins in general. His IGeneX Lyme Western Blot was inconclusive,

but Babesia FISH, IgG to Babesia duncani, IgG Bartonella, and IgM Ehrlichia were

positive. The lab of HLA typing came back looking funny. One of my friends told

me that the result looks incomplete to her. I have posted the result here:

http://slett.net/reports/2008-09-02-labcorp-hla-typing.png. Can someone help me

to identify which parts are missing? Anything at all can be interpreted from the

partial data? I am clueless in terms of what to look for. Thank you very much.

Limin