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My igenex test said I was positive for lyme but in the Short term, had just one

band in the long term....does that mean that I have not have this very

long....although my symptoms seem chronic and i feel like i could have had it

for two years at least...any thoughts.

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We had the IGG IGM tider that came back negative. We are going to a different

doctor for more testing who will use Igenex lab. Thinking ahead, if this comes

back negative we will be trying to rule out other things beside lyme. I don't

know which tests for sure to ask for in testing for lyme but don't want to rush

off to a lyme specialist unless we're sure it's lyme. Has anyone else been in

the situation where they don't know for sure it's lyme and are ruling out other

things? The testing for lyme seems so complicated...

Our finances are limited and we're trying to think strategically so we don't

spend a lot of money on specialists unnecessarily.

Advice?

Alison

________________________________

From: sw_emigre <fentonscott@...>

Sent: Sat, February 19, 2011 5:43:02 PM

Subject: [ ] Re: Igenex Test

I had a similar situation before, where I'd been sick for 3 years, but when I

took the IGenex test I was positive for short-term and negative for long-term.

My ND and my GP believe that this probably means that my immune system is so so

shot that I'm not producing the antibodies for long-term killing Lyme.

So in my experience, don't worry about the diagnosis, you for sure have Lyme.

Only catch is that you may have a long way back to health. But you'll get there,

we all will!

Paz,

S

>

> My igenex test said I was positive for lyme but in the Short term, had just

one

>band in the long term....does that mean that I have not have this very

>long....although my symptoms seem chronic and i feel like i could have had it

>for two years at least...any thoughts.

>

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>

> We had the IGG IGM tider that came back negative.

If both IgG and IgM are negative, you can still have seronegative Lyme. With a

good Western Blot test like IgeneX the chance of that happening is relatively

small (less than 5% probably), but it does occur.

Theoretically it would be a good idea to try a PCR test if the Western Blot

comes up completely negatieve. But if your finances are strained this is not

such a good idea (small chance of definite outcome, and relatively expensive

test in the US).

Did you have an erythema migrans or other sign of Borrelia infection?

It is always a good idea to be open to other explanations ...

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Regarding testing, I just wanted to make sure everyone was aware of a

recently available approach to lyme and other disease testing. It relies on

DNA rather than antibodies, and tests for dozens of organisms at the same

time, and at a cost similar to the Igenix test for lyme only. The web site

where you can order the test and get information is:

http://www.spirostattech.com <http://www.spirostattech.com/>

This seems to be an increasingly favored testing approach by Doctors. It

provides much more information at a modest cost, and is likely more

accurate.

Bob son

Fairbanks, AK

[ ] Re: Igenex Test

I had a similar situation before, where I'd been sick for 3 years, but when

I

took the IGenex test I was positive for short-term and negative for

long-term.

My ND and my GP believe that this probably means that my immune system is so

so

shot that I'm not producing the antibodies for long-term killing Lyme.

So in my experience, don't worry about the diagnosis, you for sure have

Lyme.

Only catch is that you may have a long way back to health. But you'll get

there,

we all will!

Paz,

S

>

> My igenex test said I was positive for lyme but in the Short term, had

just one

>band in the long term....does that mean that I have not have this very

>long....although my symptoms seem chronic and i feel like i could have had

it

>for two years at least...any thoughts.

>

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>

> http://www.spirostattech.com <http://www.spirostattech.com/>

>

> This seems to be an increasingly favored testing approach by Doctors. It

> provides much more information at a modest cost, and is likely more

> accurate.

thanks for the info, that's interesting. This is a different version of PCR

testing (which normally detects just one strain/species of pathogen). It is a

promising approach IMHO, especially for detecting coinfections, but I doubt it

is 'increasingly favored'.

Many scientists see this approach as extremely sensitive to contamination. If

the lab is not extremely carefull you can get false positives. I don't know any

lab in Europe that is using this for diagnosis, although it is used for

research. So interesting to see that it is on the market now in the US.

To put things into perspective: the amplification technology is similar to that

used for sequencing of whole genomes. Recent estimates say that 25% of the

currently available DNA sequences are contaminated with human DNA, due to

contamination in the lab. And this is not from commercial labs, but from

research labs where one can assume that they use the very best standards.

PCR testing in blood usually has a large chance of false negatives, I guess that

applies just the same for this test. If there is no pathogen DNA in the blood

you will not detect the pathogen. If anyone knows the specifity (risk of false

positive) and sensitivity (risk of false negative) of this labtest, I would be

interested to hear about this.

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Hi ,

 

   I had Lyme ruled out four times by testing before coming back positive on

an IGENEX test.I went untreated for 10-12 years. The standards used were

different for sensitivity. IGENEX has stated that the best way to diagnose lyme

is through symptoms as most testing is more or less unreliable. Take your LLMDs

advice and get treated if he feels you have Lyme disease. The downside of not

being treated is much worse than most admit.

 

  Peace and wellness,

 

         Jeff

From: alison kelly <greatowlherbs@...>

Subject: Re: [ ] Re: Igenex Test

Date: Monday, February 21, 2011, 1:31 PM

 

We had the IGG IGM tider that came back negative. We are going to a different

doctor for more testing who will use Igenex lab. Thinking ahead, if this comes

back negative we will be trying to rule out other things beside lyme. I don't

know which tests for sure to ask for in testing for lyme but don't want to rush

off to a lyme specialist unless we're sure it's lyme. Has anyone else been in

the situation where they don't know for sure it's lyme and are ruling out other

things? The testing for lyme seems so complicated...

Our finances are limited and we're trying to think strategically so we don't

spend a lot of money on specialists unnecessarily.

Advice?

Alison

Paz,

S

>

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What does positive in the short term mean exactly? Short term and long term?

Thank you,

Alison

________________________________

From: sw_emigre <fentonscott@...>

Sent: Sat, February 19, 2011 5:43:02 PM

Subject: [ ] Re: Igenex Test

I had a similar situation before, where I'd been sick for 3 years, but when I

took the IGenex test I was positive for short-term and negative for long-term.

My ND and my GP believe that this probably means that my immune system is so so

shot that I'm not producing the antibodies for long-term killing Lyme.

So in my experience, don't worry about the diagnosis, you for sure have Lyme.

Only catch is that you may have a long way back to health. But you'll get there,

we all will!

Paz,

S

>

> My igenex test said I was positive for lyme but in the Short term, had just

one

>band in the long term....does that mean that I have not have this very

>long....although my symptoms seem chronic and i feel like i could have had it

>for two years at least...any thoughts.

>

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Oh geesh I forgot the link to the article, sorry!!! I will pull it up when I get

to the comp and send it to you.

Sent on the Sprint® Now Network from my BlackBerry®

Re: [ ] Re: Igenex Test

We had the IGG IGM tider that came back negative. We are going to a different

doctor for more testing who will use Igenex lab. Thinking ahead, if this comes

back negative we will be trying to rule out other things beside lyme. I don't

know which tests for sure to ask for in testing for lyme but don't want to rush

off to a lyme specialist unless we're sure it's lyme. Has anyone else been in

the situation where they don't know for sure it's lyme and are ruling out other

things? The testing for lyme seems so complicated...

Our finances are limited and we're trying to think strategically so we don't

spend a lot of money on specialists unnecessarily.

Advice?

Alison

..

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