Re: CD57 Test Result

[Guest guest]

The CD57 test is not a test to determine whether or not an individual

has Lyme disease.

The test is a measure of certain specific aspects of your immune

system and it's ability to fight off infection.

Dr. Stricker and a few others are looking at how a patient's immune

system responds/reacts in relapsing and remitting chronic

neuroborreliosis.

Here's a link to a paper:

LONGTERM DECREASE IN THE CD57 LYMPHOCYTE SUBSET IN A PATIENT WITH

CHRONIC LYME DISEASE

http://www.aaem.pl/pdf/aaem0217.htm

The gist is that the CD57 lymphocytes, thought to be a subset of

natural killer cells, are downregulated in chronic infection with

borrelia.

The test could be useful in determining if therapy was effective. For

example, an initial CD57 test during a time of active infection may

indicate a decrease in the CD57 subset. The mechanism for this is

explained in the paper above.

As treatment progressed, and the patient's symptoms improved, a

subsequent CD57 test may show improvement of the numbers back to the

normal range.

Further interpretation of the results are beyond my ability.

Here you can get more details on the test:

http://www.anapsid.org/lyme/strickerpanel.html

Rick

>

> This is my first post. I had a positive Western Blot last August for

> Lyme and Babesia. I have read Buhner's book and just did a

> CD57 test (LabCorp) but do not understand the result. I would

> appreciate anyone who can help me understand this, or guide me to a

> site that does this. HNK1 (CD57) Panel, % CD8-/CD57+ Lymphs was 23 on

> 2 to 17 range. Abs.CD8-CD57+ Lymphs was 552 on 60 to 360 range. I very

> much appreciate any help. Regards,

>

[Guest guest]

There is a certain mathematical calculation to be done. My doctor did

it, but I forgot to ask for a copy of it. I think he took the CD57%

and divided it into the absolute lymphocytes to get the common CD57

value that is related to Lyme when it is below 200. My value ended up

being a 50 which was enough confirmation to my doc that my Lyme from

16 years ago never healed with antibiotics and was probably a chronic

case.

>

> This is my first post. I had a positive Western Blot last August for

> Lyme and Babesia. I have read Buhner's book and just did a

> CD57 test (LabCorp) but do not understand the result. I would

> appreciate anyone who can help me understand this, or guide me to a

> site that does this. HNK1 (CD57) Panel, % CD8-/CD57+ Lymphs was 23 on

> 2 to 17 range. Abs.CD8-CD57+ Lymphs was 552 on 60 to 360 range. I very

> much appreciate any help. Regards,

>