Re: pathogens in tick saliva

[Guest guest]

Dr Mather has patented a method for culturing pathogens including

Borrelia (Lyme) from tick SALIVA

http://www.patentstorm.us/patents/6312915-claims.html

Dr Mather also wrote a chapter in a book on pathogen transmission

http://books.google.com/books?hl=en & lr= & id=ykHNidUomr4C & oi=fnd & pg=PA68 & dq=thomas\

+mather+pathogen+in+tick+saliva & ots=D4xkTkCN74 & sig=2TlJ7EYu3nGa5nx1Lb2cTRGWXsw#P\

PA76,M1

page 76:

" Pathogens may be transmitted from ticks to animal hosts via saliva (

Borrelia,piroplasms,viruses) , regurgitation (rickettsiae), coxal fluid

(borreliae), and feces ( riskettsiae).Ixodid ticks lack coxal glands and

therefore cannot transmit via coxal fluids, "

[piroplasms are things like babesia]

I mention him as I have an excerpt from a personal communique from him to a Dr

that states: QUOTE

N. Mather, Ph.D.

Professor & Director

Center for Vector-Borne Disease

University of Rhode Island

Dr. ____,

Most certainly the saliva of an infected tick contains one or more of the

pathogens that this tick is capable of transmitting. We have a paper in which we

demonstrated that we could even culture Lyme bacteria from the saliva we

collected from infected adult ticks.

then there are these studies:

http://jcm.highwire.org/cgi/content/abstract/39/11/4145

assays of spirochetes in gut and salivary glands before and after feeding of

nymphal ticks: results show that in glands,

Before feeding there were an average of 1.2 spirochetes that increased to 20.8

at 72 hrs post attachment.

while they DO increase, there are STILL some present at the very beginning of a

feed!!!

http://www.journals.uchicago.edu/doi/pdf/10.1086/318818

this one tested transmission times of Borrelia and Ehrlichia--with infected

nymphal ticks feeding on mice, then seing how and when the mice were

infected.Only 58 mice were used so its a small sample BUT according to this, in

the first 24 hrs NO Borrelia trnasmitted In the next 24-36 hrs a marked increase

occurred.

BUT in 2/3 attempts (66%) transmission of Ehrlichia DID occur!! Researchers

concluded that " daily tick removal may not be adequate to prevent human

infection "

http://www.ncbi.nlm.nih.gov/pubmed/9532263

this one uses gerbils ( poor things) but here is an intersting result

ALL?gerbils that had ticks for more than 47 hrs infected with Borrelia

after 16.7 hrs and 28.9 hrs 50% were infected!!!!

( tick removal methods had no effect on transmission--they tested 3 methods)

Id say this last one shows a faster transmission than whats usually stated!!

and finally

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=266148

states that partially fed ticks will transmit faster than unfed ticks--so that

means that if the tick thats biting you had previously tried to feed on another

animal/human and was scratched off or fell off and then it attached to you--the

safe wait time is invalid and it can be infective far faster!!

http://www.ajtmh.org/cgi/content/abstract/71/3/268?? POW Virus--in 15 min

transmits!!

is this what you needed??? if not let me know and Ill try to find better studies

Finette

[the gene pool could use a little chlorine!]

[Guest guest]

Thanks Finette!

This is great!

Cat

>

> is this what you needed??? if not let me know and Ill try to find better

studies

>

> Finette

>

>