Re: VERY Low Dose Naltrexone

[Guest guest]

For those of you in the first 3 to 6 months of LDN therapy, you may experience

temporarilly extra stiffness, headache, numbness, vertigo, sleeplessness,

diuretic effect, loss of appetite, extra fatigue, etc.

Below is by Dr. Bob Lawrence who takes LDN himself

When starting this LDN(Low Dose Naltrexone) therapy in the treatment of

autoimmune illness, there may also be some initial transient, though temporary,

increase in symptoms.

Experience in using this method has demonstrated most commonly, such as

disturbed sleep, occasionally with vivid, bizarre and disturbing dreams,

tiredness, fatigue, spasm and pain.

Rarely, other transient symptoms have included more severe pain and spasm,

headache, diarrhea or vomiting. These additional symptoms would appear to be

associated with the previous frequent use of strong analgesics, which

effectively create an addiction and dependency, thus increasing the body's

sensitivity to pain.

In addition, because LDN stimulates the immune system and many of the drugs

routinely used by the NHS in the treatment of MS and autoimmune disease further

suppress the immune system, LDN cannot be used in company with steroids, beta

interferon, methotrexate, azathioprine or mitozantrone or any other immune

suppressant drug. If there is any doubt, please submit a full list of the drugs

you are presently taking so that their compatibility may be assessed.

In addition, because LDN will also block the analgesic effects of any opiate

drugs (includes codeine, dihydrocodeine, morphine, pethidine or diamorphine)

presently being taken, the use of LDN will initially greatly increase the level

of pain experienced. It is therefore advisable that any opiate-like drugs be

discontinued at least two weeks before this treatment is initiated. When

starting the treatment it is essential that any untoward or adverse side-effects

are reported immediately so that the treatment process can be further assessed

and, if necessary, modified.

============

Below is by Dr. Jaquelyn McCandless

Other reasons of negative responses to LDN by Dr. Jaquelyn McCandless

Re: ldn

As usual, I need to emphasize that seldom is LDN a stand-alone treatment, but

accompanies other strategies their body needs, especially a healthy diet. No

sugar, dairy or gluten.

It takes some people longer to respond to LDN, and they may be colonized with

pathogenic yeast and bacteria that could be slowing response.

There is a phenomenon that happens to some people that as the immune system is

shifting (usually from T2 to T1) right after starting LDN, the immune system

drops and people get an infection, cold, flu, cold sore, etc. which is usually

short lived. Candida tends to overgrow or a virus will flare up. These

infections are usually short-lived unless something like candida and gut

bacteria needs treatment.

Are you a big bread/carbohydrate/sugar eater?

Ever been tested for candida (yeast) or gut bacterial infestation?

Ever been checked for hypothyroidism?

Would you be willing to stop all casein (milk products) and gluten (wheat, rye,

barley and oats) for a week and see if you feel better? A study done several

years ago showed that 30% of us have some degree of celiac disease

(intolerance/allegy to wheat) even though the clinical symptoms may not be

obvious enough to alert most people to that. When anyone in that 30% of persons

stops eating wheat, they feel a lot better. The LDN may be acting like the

opioid antagonist it is and causing a withdrawal reaction from taking away your

fix, even if only for a few hours.

Try to hang in for awhile longer, and it will probably get better. These

setbacks usually do not last long unless something like a yeast infection is

stubborn without specific treatment.

Dr. JM

=====

Q: Dr. JM or anyone- Does LDN cause candida?

A: LDN has been noted to aggravate yeast infections and other latent pathogens,

viruses, etc. as the immune system is making early adjustments. It is good to

have natural yeast remedies on board when LDN is started (grapefruit seed

extract, Candex, lauricidin, hi-potency probiotics, etc) to help offset this

possibility. (And of course a good dietary regime that does not encourage gut

inflammation which is usually the predecessor to pathogen invasion).

Dr. Jaquelyn McCandless

Dr JM responded on the LDN-Autism forum recently regarding anxiety as a

side-effect of LDN. She said that about 30% of the population has celiac disease

to some degree, and that celiac is not an all or nothing thing. Therefore, she

postulates that, like with autistic kids, there is something going on in the gut

with many of us. This would be an allergic response to gluten (in wheat and, I

think, rye barley, oats) and possibly casein (milk protein) in the gut and an

incomplete digestion of these proteins. The result is a release of semi-digested

food polypeptides

into the blood and brain, where they don't belong, and which act as

opiates--they stimulate the autistic kids to act out or to space out! The

autistic kids, and the rest of us who have some degree of allergy to gluten

and/or casein, are " high " on these incompletely digested molecules. When LDN

comes along in the blood stream and blocks the opiate effect, we get anxious.

So Dr JM absolutely recommends addressing diet first with autistic kids, but

also with others who have problems acclimating to LDN.

posted by

There have been approx. 40 plus instances on the many various LDN forums where

LDN caused severe increased pain and the person later found out they had been

misdiagnosed and actually were suffering from chronic lyme. LDN can cause

increase in pain in those with lyme and LDN can also bring chronic lyme to the

forefront, are these herx's, no one knows. Many times a person with lyme will

have to stop taking LDN and get proper lyme treatment for 3 to 4 or more months

and then later try to re-introduce the LDN back into the mix. Some succeed to

continue to take LDN while getting Lyme treatment.

Lyme mimics so many autoimmune system illnesses

http://ldn.proboards.com/index.cgi?board=links & action=display & thread=926

, LDN user over 7 yrs for chronic progressive MS, dx'd 1989, I started on

4.5mg nightly and I continue to take 4.5mg nightly. I experienced extra

stiffness for 3 months, numb hands for 3 weeks and muscle twitching off and on

for 6 months but all that faded away as my body adjusted to the LDN endorphin

boost. The extra symptoms kicked in around the second and 3rd weeks on LDN. Been

in remission for 7yrs on LDN.

[Guest guest]

Hi,

This line concerns me: " LDN cannot be used in company with steroids, beta

interferon, methotrexate, azathioprine or mitozantrone or any other immune

suppressant drug. "

I am currently taking hydrocortisone for adrenal fatigue. Does this apply, or

is he referring to heavy steroids like prednisone, prednisolone, etc.? There's

no way I can discontinue right now, although my hope is that I'll be able to.

Scared...

Thanks,

Tara

>

>

> For those of you in the first 3 to 6 months of LDN therapy, you may experience

temporarilly extra stiffness, headache, numbness, vertigo, sleeplessness,

diuretic effect, loss of appetite, extra fatigue, etc.

>

> Below is by Dr. Bob Lawrence who takes LDN himself

>

> When starting this LDN(Low Dose Naltrexone) therapy in the treatment of

autoimmune illness, there may also be some initial transient, though temporary,

increase in symptoms.

>

> Experience in using this method has demonstrated most commonly, such as

disturbed sleep, occasionally with vivid, bizarre and disturbing dreams,

tiredness, fatigue, spasm and pain.

>

> Rarely, other transient symptoms have included more severe pain and spasm,

headache, diarrhea or vomiting. These additional symptoms would appear to be

associated with the previous frequent use of strong analgesics, which

effectively create an addiction and dependency, thus increasing the body's

sensitivity to pain.

>

> In addition, because LDN stimulates the immune system and many of the drugs

routinely used by the NHS in the treatment of MS and autoimmune disease further

suppress the immune system, LDN cannot be used in company with steroids, beta

interferon, methotrexate, azathioprine or mitozantrone or any other immune

suppressant drug. If there is any doubt, please submit a full list of the drugs

you are presently taking so that their compatibility may be assessed.

>

> In addition, because LDN will also block the analgesic effects of any opiate

drugs (includes codeine, dihydrocodeine, morphine, pethidine or diamorphine)

presently being taken, the use of LDN will initially greatly increase the level

of pain experienced. It is therefore advisable that any opiate-like drugs be

discontinued at least two weeks before this treatment is initiated. When

starting the treatment it is essential that any untoward or adverse side-effects

are reported immediately so that the treatment process can be further assessed

and, if necessary, modified.

> ============

> Below is by Dr. Jaquelyn McCandless

> Other reasons of negative responses to LDN by Dr. Jaquelyn McCandless

>

> Re: ldn

>

> As usual, I need to emphasize that seldom is LDN a stand-alone treatment, but

accompanies other strategies their body needs, especially a healthy diet. No

sugar, dairy or gluten.

>

> It takes some people longer to respond to LDN, and they may be colonized with

pathogenic yeast and bacteria that could be slowing response.

>

> There is a phenomenon that happens to some people that as the immune system is

shifting (usually from T2 to T1) right after starting LDN, the immune system

drops and people get an infection, cold, flu, cold sore, etc. which is usually

short lived. Candida tends to overgrow or a virus will flare up. These

infections are usually short-lived unless something like candida and gut

bacteria needs treatment.

>

> Are you a big bread/carbohydrate/sugar eater?

> Ever been tested for candida (yeast) or gut bacterial infestation?

> Ever been checked for hypothyroidism?

>

> Would you be willing to stop all casein (milk products) and gluten (wheat,

rye, barley and oats) for a week and see if you feel better? A study done

several years ago showed that 30% of us have some degree of celiac disease

(intolerance/allegy to wheat) even though the clinical symptoms may not be

obvious enough to alert most people to that. When anyone in that 30% of persons

stops eating wheat, they feel a lot better. The LDN may be acting like the

opioid antagonist it is and causing a withdrawal reaction from taking away your

fix, even if only for a few hours.

>

> Try to hang in for awhile longer, and it will probably get better. These

setbacks usually do not last long unless something like a yeast infection is

stubborn without specific treatment.

> Dr. JM

> =====

>

> Q: Dr. JM or anyone- Does LDN cause candida?

>

> A: LDN has been noted to aggravate yeast infections and other latent

pathogens, viruses, etc. as the immune system is making early adjustments. It is

good to have natural yeast remedies on board when LDN is started (grapefruit

seed extract, Candex, lauricidin, hi-potency probiotics, etc) to help offset

this possibility. (And of course a good dietary regime that does not encourage

gut inflammation which is usually the predecessor to pathogen invasion).

>

> Dr. Jaquelyn McCandless

>

> Dr JM responded on the LDN-Autism forum recently regarding anxiety as a

side-effect of LDN. She said that about 30% of the population has celiac disease

to some degree, and that celiac is not an all or nothing thing. Therefore, she

postulates that, like with autistic kids, there is something going on in the gut

with many of us. This would be an allergic response to gluten (in wheat and, I

think, rye barley, oats) and possibly casein (milk protein) in the gut and an

incomplete digestion of these proteins. The result is a release of semi-digested

food polypeptides

> into the blood and brain, where they don't belong, and which act as

opiates--they stimulate the autistic kids to act out or to space out! The

autistic kids, and the rest of us who have some degree of allergy to gluten

and/or casein, are " high " on these incompletely digested molecules. When LDN

comes along in the blood stream and blocks the opiate effect, we get anxious.

>

> So Dr JM absolutely recommends addressing diet first with autistic kids, but

also with others who have problems acclimating to LDN.

>

> posted by

>

> There have been approx. 40 plus instances on the many various LDN forums where

LDN caused severe increased pain and the person later found out they had been

misdiagnosed and actually were suffering from chronic lyme. LDN can cause

increase in pain in those with lyme and LDN can also bring chronic lyme to the

forefront, are these herx's, no one knows. Many times a person with lyme will

have to stop taking LDN and get proper lyme treatment for 3 to 4 or more months

and then later try to re-introduce the LDN back into the mix. Some succeed to

continue to take LDN while getting Lyme treatment.

>

> Lyme mimics so many autoimmune system illnesses

> http://ldn.proboards.com/index.cgi?board=links & action=display & thread=926

>

> , LDN user over 7 yrs for chronic progressive MS, dx'd 1989, I started

on 4.5mg nightly and I continue to take 4.5mg nightly. I experienced extra

stiffness for 3 months, numb hands for 3 weeks and muscle twitching off and on

for 6 months but all that faded away as my body adjusted to the LDN endorphin

boost. The extra symptoms kicked in around the second and 3rd weeks on LDN. Been

in remission for 7yrs on LDN.

>

[Guest guest]

low doses of steroids are fine and I believe the amounts of hc used are quite low so you would be fineOn Fri, Dec 31, 2010 at 11:06 AM, tcopat <tcopat@...> wrote:

Hi,

This line concerns me:   " LDN cannot be used in company with steroids, beta interferon, methotrexate, azathioprine or mitozantrone or any other immune suppressant drug. "

I am currently taking hydrocortisone for adrenal fatigue.  Does this apply, or is he referring to heavy steroids like prednisone, prednisolone, etc.?  There's no way I can discontinue right now, although my hope is that I'll be able to.

Scared...

Thanks,

Tara

>

>

> For those of you in the first 3 to 6 months of LDN therapy, you may experience temporarilly extra stiffness, headache, numbness, vertigo, sleeplessness, diuretic effect, loss of appetite, extra fatigue, etc.

>

> Below is by Dr. Bob Lawrence who takes LDN himself

>

> When starting this LDN(Low Dose Naltrexone) therapy in the treatment of autoimmune illness, there may also be some initial transient, though temporary, increase in symptoms.

>

> Experience in using this method has demonstrated most commonly, such as disturbed sleep, occasionally with vivid, bizarre and disturbing dreams, tiredness, fatigue, spasm and pain.

>

> Rarely, other transient symptoms have included more severe pain and spasm, headache, diarrhea or vomiting. These additional symptoms would appear to be associated with the previous frequent use of strong analgesics, which effectively create an addiction and dependency, thus increasing the body's sensitivity to pain.

>

> In addition, because LDN stimulates the immune system and many of the drugs routinely used by the NHS in the treatment of MS and autoimmune disease further suppress the immune system, LDN cannot be used in company with steroids, beta interferon, methotrexate, azathioprine or mitozantrone or any other immune suppressant drug. If there is any doubt, please submit a full list of the drugs you are presently taking so that their compatibility may be assessed.

>

> In addition, because LDN will also block the analgesic effects of any opiate drugs (includes codeine, dihydrocodeine, morphine, pethidine or diamorphine) presently being taken, the use of LDN will initially greatly increase the level of pain experienced. It is therefore advisable that any opiate-like drugs be discontinued at least two weeks before this treatment is initiated. When starting the treatment it is essential that any untoward or adverse side-effects are reported immediately so that the treatment process can be further assessed and, if necessary, modified.

> ============

> Below is by Dr. Jaquelyn McCandless

> Other reasons of negative responses to LDN by Dr. Jaquelyn McCandless

>

> Re: ldn

>

> As usual, I need to emphasize that seldom is LDN a stand-alone treatment, but accompanies other strategies their body needs, especially a healthy diet. No sugar, dairy or gluten.

>

> It takes some people longer to respond to LDN, and they may be colonized with pathogenic yeast and bacteria that could be slowing response.

>

> There is a phenomenon that happens to some people that as the immune system is shifting (usually from T2 to T1) right after starting LDN, the immune system drops and people get an infection, cold, flu, cold sore, etc. which is usually short lived. Candida tends to overgrow or a virus will flare up. These infections are usually short-lived unless something like candida and gut bacteria needs treatment.

>

> Are you a big bread/carbohydrate/sugar eater?

> Ever been tested for candida (yeast) or gut bacterial infestation?

> Ever been checked for hypothyroidism?

>

> Would you be willing to stop all casein (milk products) and gluten (wheat, rye, barley and oats) for a week and see if you feel better? A study done several years ago showed that 30% of us have some degree of celiac disease (intolerance/allegy to wheat) even though the clinical symptoms may not be obvious enough to alert most people to that. When anyone in that 30% of persons stops eating wheat, they feel a lot better. The LDN may be acting like the opioid antagonist it is and causing a withdrawal reaction from taking away your fix, even if only for a few hours.

>

> Try to hang in for awhile longer, and it will probably get better. These setbacks usually do not last long unless something like a yeast infection is stubborn without specific treatment.

> Dr. JM

> =====

>

> Q: Dr. JM or anyone- Does LDN cause candida?

>

> A: LDN has been noted to aggravate yeast infections and other latent pathogens, viruses, etc. as the immune system is making early adjustments. It is good to have natural yeast remedies on board when LDN is started (grapefruit seed extract, Candex, lauricidin, hi-potency probiotics, etc) to help offset this possibility. (And of course a good dietary regime that does not encourage gut inflammation which is usually the predecessor to pathogen invasion).

>

> Dr. Jaquelyn McCandless

>

> Dr JM responded on the LDN-Autism forum recently regarding anxiety as a side-effect of LDN. She said that about 30% of the population has celiac disease to some degree, and that celiac is not an all or nothing thing. Therefore, she postulates that, like with autistic kids, there is something going on in the gut with many of us. This would be an allergic response to gluten (in wheat and, I think, rye barley, oats) and possibly casein (milk protein) in the gut and an incomplete digestion of these proteins. The result is a release of semi-digested food polypeptides

> into the blood and brain, where they don't belong, and which act as opiates--they stimulate the autistic kids to act out or to space out! The autistic kids, and the rest of us who have some degree of allergy to gluten and/or casein, are " high " on these incompletely digested molecules. When LDN comes along in the blood stream and blocks the opiate effect, we get anxious.

>

> So Dr JM absolutely recommends addressing diet first with autistic kids, but also with others who have problems acclimating to LDN.

>

> posted by

>

> There have been approx. 40 plus instances on the many various LDN forums where LDN caused severe increased pain and the person later found out they had been misdiagnosed and actually were suffering from chronic lyme. LDN can cause increase in pain in those with lyme and LDN can also bring chronic lyme to the forefront, are these herx's, no one knows. Many times a person with lyme will have to stop taking LDN and get proper lyme treatment for 3 to 4 or more months and then later try to re-introduce the LDN back into the mix.  Some succeed to continue to take LDN while getting Lyme treatment.

>

> Lyme mimics so many autoimmune system illnesses

> http://ldn.proboards.com/index.cgi?board=links & action=display & thread=926

>

> , LDN user over 7 yrs for chronic progressive MS, dx'd 1989, I started on 4.5mg nightly and I continue to take 4.5mg nightly.  I experienced extra stiffness for 3 months, numb hands for 3 weeks and muscle twitching off and on for 6 months but all that faded away as my body adjusted to the LDN endorphin boost. The extra symptoms kicked in around the second and 3rd weeks on LDN. Been in remission for 7yrs on LDN.

>

------------------------------------

[Guest guest]

Hi Tara, This statement from Dr Bob Lawrence was written 5-6 years ago. As when I last saw Dr Lawrence (about 4 weeks ago), he is no longer of the opinion stated below and intends to update this (his views) at his earliest convenience. The only thing you cannot combine LDN with is opiates. I personally have combined prednisone (40mg) with LDN and found it more beneficial than just taking steroids on its own. Dr Lawrence is my LDN prescribing Dr so in my view, I don’t think you have anything to be scared of. Best wishes to you and all for 2011. Jayne Crocker www.LDNNow.comImportant! Please sign our LDN petition to the European Parliament by clicking heretel: +44 (0) 7877 492 669Dr Steele MBE, talking about LDNLDNNow are a political/pressure group of individuals dedicated to getting Low Dose Naltrexone (LDN) accepted into modern medicine and trialled for the myriad of uses it shows benefit for. . From: low dose naltrexone [mailto:low dose naltrexone ] On Behalf Of tcopatSent: 31 December 2010 17:07low dose naltrexone Subject: [low dose naltrexone] Re: VERY Low Dose Naltrexone Hi,This line concerns me: " LDN cannot be used in company with steroids, beta interferon, methotrexate, azathioprine or mitozantrone or any other immune suppressant drug. " I am currently taking hydrocortisone for adrenal fatigue. Does this apply, or is he referring to heavy steroids like prednisone, prednisolone, etc.? There's no way I can discontinue right now, although my hope is that I'll be able to.Scared...Thanks,Tara>> > For those of you in the first 3 to 6 months of LDN therapy, you may experience temporarilly extra stiffness, headache, numbness, vertigo, sleeplessness, diuretic effect, loss of appetite, extra fatigue, etc.> > Below is by Dr. Bob Lawrence who takes LDN himself> > When starting this LDN(Low Dose Naltrexone) therapy in the treatment of autoimmune illness, there may also be some initial transient, though temporary, increase in symptoms. > > Experience in using this method has demonstrated most commonly, such as disturbed sleep, occasionally with vivid, bizarre and disturbing dreams, tiredness, fatigue, spasm and pain. > > Rarely, other transient symptoms have included more severe pain and spasm, headache, diarrhea or vomiting. These additional symptoms would appear to be associated with the previous frequent use of strong analgesics, which effectively create an addiction and dependency, thus increasing the body's sensitivity to pain. > > In addition, because LDN stimulates the immune system and many of the drugs routinely used by the NHS in the treatment of MS and autoimmune disease further suppress the immune system, LDN cannot be used in company with steroids, beta interferon, methotrexate, azathioprine or mitozantrone or any other immune suppressant drug. If there is any doubt, please submit a full list of the drugs you are presently taking so that their compatibility may be assessed. > > In addition, because LDN will also block the analgesic effects of any opiate drugs (includes codeine, dihydrocodeine, morphine, pethidine or diamorphine) presently being taken, the use of LDN will initially greatly increase the level of pain experienced. It is therefore advisable that any opiate-like drugs be discontinued at least two weeks before this treatment is initiated. When starting the treatment it is essential that any untoward or adverse side-effects are reported immediately so that the treatment process can be further assessed and, if necessary, modified. > ============> Below is by Dr. Jaquelyn McCandless> Other reasons of negative responses to LDN by Dr. Jaquelyn McCandless> > Re: ldn > > As usual, I need to emphasize that seldom is LDN a stand-alone treatment, but accompanies other strategies their body needs, especially a healthy diet. No sugar, dairy or gluten.> > It takes some people longer to respond to LDN, and they may be colonized with pathogenic yeast and bacteria that could be slowing response.> > There is a phenomenon that happens to some people that as the immune system is shifting (usually from T2 to T1) right after starting LDN, the immune system drops and people get an infection, cold, flu, cold sore, etc. which is usually short lived. Candida tends to overgrow or a virus will flare up. These infections are usually short-lived unless something like candida and gut bacteria needs treatment. > > Are you a big bread/carbohydrate/sugar eater? > Ever been tested for candida (yeast) or gut bacterial infestation? > Ever been checked for hypothyroidism? > > Would you be willing to stop all casein (milk products) and gluten (wheat, rye, barley and oats) for a week and see if you feel better? A study done several years ago showed that 30% of us have some degree of celiac disease (intolerance/allegy to wheat) even though the clinical symptoms may not be obvious enough to alert most people to that. When anyone in that 30% of persons stops eating wheat, they feel a lot better. The LDN may be acting like the opioid antagonist it is and causing a withdrawal reaction from taking away your fix, even if only for a few hours.> > Try to hang in for awhile longer, and it will probably get better. These setbacks usually do not last long unless something like a yeast infection is stubborn without specific treatment. > Dr. JM> =====> > Q: Dr. JM or anyone- Does LDN cause candida? > > A: LDN has been noted to aggravate yeast infections and other latent pathogens, viruses, etc. as the immune system is making early adjustments. It is good to have natural yeast remedies on board when LDN is started (grapefruit seed extract, Candex, lauricidin, hi-potency probiotics, etc) to help offset this possibility. (And of course a good dietary regime that does not encourage gut inflammation which is usually the predecessor to pathogen invasion). > > Dr. Jaquelyn McCandless> > Dr JM responded on the LDN-Autism forum recently regarding anxiety as a side-effect of LDN. She said that about 30% of the population has celiac disease to some degree, and that celiac is not an all or nothing thing. Therefore, she postulates that, like with autistic kids, there is something going on in the gut with many of us. This would be an allergic response to gluten (in wheat and, I think, rye barley, oats) and possibly casein (milk protein) in the gut and an incomplete digestion of these proteins. The result is a release of semi-digested food polypeptides> into the blood and brain, where they don't belong, and which act as opiates--they stimulate the autistic kids to act out or to space out! The autistic kids, and the rest of us who have some degree of allergy to gluten and/or casein, are " high " on these incompletely digested molecules. When LDN comes along in the blood stream and blocks the opiate effect, we get anxious.> > So Dr JM absolutely recommends addressing diet first with autistic kids, but also with others who have problems acclimating to LDN. > > posted by > > There have been approx. 40 plus instances on the many various LDN forums where LDN caused severe increased pain and the person later found out they had been misdiagnosed and actually were suffering from chronic lyme. LDN can cause increase in pain in those with lyme and LDN can also bring chronic lyme to the forefront, are these herx's, no one knows. Many times a person with lyme will have to stop taking LDN and get proper lyme treatment for 3 to 4 or more months and then later try to re-introduce the LDN back into the mix. Some succeed to continue to take LDN while getting Lyme treatment.> > Lyme mimics so many autoimmune system illnesses> http://ldn.proboards.com/index.cgi?board=links & action=display & thread=926> > , LDN user over 7 yrs for chronic progressive MS, dx'd 1989, I started on 4.5mg nightly and I continue to take 4.5mg nightly. I experienced extra stiffness for 3 months, numb hands for 3 weeks and muscle twitching off and on for 6 months but all that faded away as my body adjusted to the LDN endorphin boost. The extra symptoms kicked in around the second and 3rd weeks on LDN. Been in remission for 7yrs on LDN.>

[Guest guest]

he's referring to heavy steroids

==============================

> >

> >

> > For those of you in the first 3 to 6 months of LDN therapy, you may

experience temporarilly extra stiffness, headache, numbness, vertigo,

sleeplessness, diuretic effect, loss of appetite, extra fatigue, etc.

> >

> > Below is by Dr. Bob Lawrence who takes LDN himself

> >

> > When starting this LDN(Low Dose Naltrexone) therapy in the treatment of

autoimmune illness, there may also be some initial transient, though temporary,

increase in symptoms.

> >

> > Experience in using this method has demonstrated most commonly, such as

disturbed sleep, occasionally with vivid, bizarre and disturbing dreams,

tiredness, fatigue, spasm and pain.

> >

> > Rarely, other transient symptoms have included more severe pain and spasm,

headache, diarrhea or vomiting. These additional symptoms would appear to be

associated with the previous frequent use of strong analgesics, which

effectively create an addiction and dependency, thus increasing the body's

sensitivity to pain.

> >

> > In addition, because LDN stimulates the immune system and many of the drugs

routinely used by the NHS in the treatment of MS and autoimmune disease further

suppress the immune system, LDN cannot be used in company with steroids, beta

interferon, methotrexate, azathioprine or mitozantrone or any other immune

suppressant drug. If there is any doubt, please submit a full list of the drugs

you are presently taking so that their compatibility may be assessed.

> >

> > In addition, because LDN will also block the analgesic effects of any opiate

drugs (includes codeine, dihydrocodeine, morphine, pethidine or diamorphine)

presently being taken, the use of LDN will initially greatly increase the level

of pain experienced. It is therefore advisable that any opiate-like drugs be

discontinued at least two weeks before this treatment is initiated. When

starting the treatment it is essential that any untoward or adverse side-effects

are reported immediately so that the treatment process can be further assessed

and, if necessary, modified.

> > ============

> > Below is by Dr. Jaquelyn McCandless

> > Other reasons of negative responses to LDN by Dr. Jaquelyn McCandless

> >

> > Re: ldn

> >

> > As usual, I need to emphasize that seldom is LDN a stand-alone treatment,

but accompanies other strategies their body needs, especially a healthy diet. No

sugar, dairy or gluten.

> >

> > It takes some people longer to respond to LDN, and they may be colonized

with pathogenic yeast and bacteria that could be slowing response.

> >

> > There is a phenomenon that happens to some people that as the immune system

is shifting (usually from T2 to T1) right after starting LDN, the immune system

drops and people get an infection, cold, flu, cold sore, etc. which is usually

short lived. Candida tends to overgrow or a virus will flare up. These

infections are usually short-lived unless something like candida and gut

bacteria needs treatment.

> >

> > Are you a big bread/carbohydrate/sugar eater?

> > Ever been tested for candida (yeast) or gut bacterial infestation?

> > Ever been checked for hypothyroidism?

> >

> > Would you be willing to stop all casein (milk products) and gluten (wheat,

rye, barley and oats) for a week and see if you feel better? A study done

several years ago showed that 30% of us have some degree of celiac disease

(intolerance/allegy to wheat) even though the clinical symptoms may not be

obvious enough to alert most people to that. When anyone in that 30% of persons

stops eating wheat, they feel a lot better. The LDN may be acting like the

opioid antagonist it is and causing a withdrawal reaction from taking away your

fix, even if only for a few hours.

> >

> > Try to hang in for awhile longer, and it will probably get better. These

setbacks usually do not last long unless something like a yeast infection is

stubborn without specific treatment.

> > Dr. JM

> > =====

> >

> > Q: Dr. JM or anyone- Does LDN cause candida?

> >

> > A: LDN has been noted to aggravate yeast infections and other latent

pathogens, viruses, etc. as the immune system is making early adjustments. It is

good to have natural yeast remedies on board when LDN is started (grapefruit

seed extract, Candex, lauricidin, hi-potency probiotics, etc) to help offset

this possibility. (And of course a good dietary regime that does not encourage

gut inflammation which is usually the predecessor to pathogen invasion).

> >

> > Dr. Jaquelyn McCandless

> >

> > Dr JM responded on the LDN-Autism forum recently regarding anxiety as

a side-effect of LDN. She said that about 30% of the population has celiac

disease to some degree, and that celiac is not an all or nothing thing.

Therefore, she postulates that, like with autistic kids, there is something

going on in the gut with many of us. This would be an allergic response to

gluten (in wheat and, I think, rye barley, oats) and possibly casein (milk

protein) in the gut and an incomplete digestion of these proteins. The result is

a release of semi-digested food polypeptides

> > into the blood and brain, where they don't belong, and which act as

opiates--they stimulate the autistic kids to act out or to space out! The

autistic kids, and the rest of us who have some degree of allergy to gluten

and/or casein, are " high " on these incompletely digested molecules. When LDN

comes along in the blood stream and blocks the opiate effect, we get anxious.

> >

> > So Dr JM absolutely recommends addressing diet first with autistic kids, but

also with others who have problems acclimating to LDN.

> >

> > posted by

> >

> > There have been approx. 40 plus instances on the many various LDN forums

where LDN caused severe increased pain and the person later found out they had

been misdiagnosed and actually were suffering from chronic lyme. LDN can cause

increase in pain in those with lyme and LDN can also bring chronic lyme to the

forefront, are these herx's, no one knows. Many times a person with lyme will

have to stop taking LDN and get proper lyme treatment for 3 to 4 or more months

and then later try to re-introduce the LDN back into the mix. Some succeed to

continue to take LDN while getting Lyme treatment.

> >

> > Lyme mimics so many autoimmune system illnesses

> > http://ldn.proboards.com/index.cgi?board=links & action=display & thread=926

> >

> > , LDN user over 7 yrs for chronic progressive MS, dx'd 1989, I started

on 4.5mg nightly and I continue to take 4.5mg nightly. I experienced extra

stiffness for 3 months, numb hands for 3 weeks and muscle twitching off and on

for 6 months but all that faded away as my body adjusted to the LDN endorphin

boost. The extra symptoms kicked in around the second and 3rd weeks on LDN. Been

in remission for 7yrs on LDN.

> >

>

[Guest guest]

Dr Bob Lawrence was referring to any dose of steroids in that particular statement. Even in the summer when I reluctantly had to go on steroids at that dose, he was against this. He is very anti steroids no doubt about it, aren’t we all? Unfortunately some times if you’re that ill, LDN and antioxidants just aren’t enough and one is then put into a very unfortunate position where you have to weigh everything up and make a decision - even ones we don’t favour. During the past year a number of patients of Dr Lawrence have had to combine the two and reported benefits by doing so. I believe using LDN as a biotherapy when the going gets tough is currently his way of thinking and taking steroids with LDN certainly won’t do you any harm. I think it’s a crying shame that people are put off starting LDN to better their health when their impressions are:- LDN will only work if you follow a particular diet regimeonce you’re on LDN, you cannot and must not take any other meds you need to get up to 4.5mg to reap full benefitsit will take 18 months before you even start to see any benefits with LDN I know the above isn’t what has actually been said, but for some reason this is how it’s being perceived and shared, therefore putting a stop to others looking into LDN. New evidence about this wonderful treatment we are all taking is appearing all the time. I think we owe it to ourselves and others to bear this in mind, especially when someone wants to share they are trying out a new regime, hoping it may be of benefit to others. Isn’t ‘out of the box’ thinking what we all complain our mainstream Drs aren’t doing re LDN? And yet, it does appear when a LDN user does this by changing their regime, they (as somebody else put it) gets “pounced on”. LDN is the ideal combination therapy as it does NOT conflict with anything else apart from opiates. Tara, from what I’ve been looking at, the reason you take HC for adrenal fatigue is because it is the kidneys that make HC in the body normally. If you have adrenal fatigue you are taking it to make up for the loss of HC in your own system. The risk here, from what I’ve been reading is that you may possibly make the problem worse because your kidneys will not make HC if you are providing it from outside. Therefore I don’t think there’s any problem taking LDN with HC and they do NOT conflict. One of the most damaging thing to LDN, is that we make out LDN is an exclusive therapy. We want Doctors to add it to their toolbox and want them to combine it with other meds that they are use to prescribing. There is no problem with this and they will accept its use more readily in modern medicine if they can combine it with others. Jayne Crocker www.LDNNow.comImportant! Please sign our LDN petition to the European Parliament by clicking heretel: +44 (0) 7877 492 669Dr Steele MBE, talking about LDNLDNNow are a political/pressure group of individuals dedicated to getting Low Dose Naltrexone (LDN) accepted into modern medicine and trialled for the myriad of uses it shows benefit for. . From: low dose naltrexone [mailto:low dose naltrexone ] On Behalf Of bren_ldnSent: 01 January 2011 02:49low dose naltrexone Subject: [low dose naltrexone] Re: VERY Low Dose Naltrexone he's referring to heavy steroids==============================> >> > > > For those of you in the first 3 to 6 months of LDN therapy, you may experience temporarilly extra stiffness, headache, numbness, vertigo, sleeplessness, diuretic effect, loss of appetite, extra fatigue, etc.> > > > Below is by Dr. Bob Lawrence who takes LDN himself> > > > When starting this LDN(Low Dose Naltrexone) therapy in the treatment of autoimmune illness, there may also be some initial transient, though temporary, increase in symptoms. > > > > Experience in using this method has demonstrated most commonly, such as disturbed sleep, occasionally with vivid, bizarre and disturbing dreams, tiredness, fatigue, spasm and pain. > > > > Rarely, other transient symptoms have included more severe pain and spasm, headache, diarrhea or vomiting. These additional symptoms would appear to be associated with the previous frequent use of strong analgesics, which effectively create an addiction and dependency, thus increasing the body's sensitivity to pain. > > > > In addition, because LDN stimulates the immune system and many of the drugs routinely used by the NHS in the treatment of MS and autoimmune disease further suppress the immune system, LDN cannot be used in company with steroids, beta interferon, methotrexate, azathioprine or mitozantrone or any other immune suppressant drug. If there is any doubt, please submit a full list of the drugs you are presently taking so that their compatibility may be assessed. > > > > In addition, because LDN will also block the analgesic effects of any opiate drugs (includes codeine, dihydrocodeine, morphine, pethidine or diamorphine) presently being taken, the use of LDN will initially greatly increase the level of pain experienced. It is therefore advisable that any opiate-like drugs be discontinued at least two weeks before this treatment is initiated. When starting the treatment it is essential that any untoward or adverse side-effects are reported immediately so that the treatment process can be further assessed and, if necessary, modified. > > ============> > Below is by Dr. Jaquelyn McCandless> > Other reasons of negative responses to LDN by Dr. Jaquelyn McCandless> > > > Re: ldn > > > > As usual, I need to emphasize that seldom is LDN a stand-alone treatment, but accompanies other strategies their body needs, especially a healthy diet. No sugar, dairy or gluten.> > > > It takes some people longer to respond to LDN, and they may be colonized with pathogenic yeast and bacteria that could be slowing response.> > > > There is a phenomenon that happens to some people that as the immune system is shifting (usually from T2 to T1) right after starting LDN, the immune system drops and people get an infection, cold, flu, cold sore, etc. which is usually short lived. Candida tends to overgrow or a virus will flare up. These infections are usually short-lived unless something like candida and gut bacteria needs treatment. > > > > Are you a big bread/carbohydrate/sugar eater? > > Ever been tested for candida (yeast) or gut bacterial infestation? > > Ever been checked for hypothyroidism? > > > > Would you be willing to stop all casein (milk products) and gluten (wheat, rye, barley and oats) for a week and see if you feel better? A study done several years ago showed that 30% of us have some degree of celiac disease (intolerance/allegy to wheat) even though the clinical symptoms may not be obvious enough to alert most people to that. When anyone in that 30% of persons stops eating wheat, they feel a lot better. The LDN may be acting like the opioid antagonist it is and causing a withdrawal reaction from taking away your fix, even if only for a few hours.> > > > Try to hang in for awhile longer, and it will probably get better. These setbacks usually do not last long unless something like a yeast infection is stubborn without specific treatment. > > Dr. JM> > =====> > > > Q: Dr. JM or anyone- Does LDN cause candida? > > > > A: LDN has been noted to aggravate yeast infections and other latent pathogens, viruses, etc. as the immune system is making early adjustments. It is good to have natural yeast remedies on board when LDN is started (grapefruit seed extract, Candex, lauricidin, hi-potency probiotics, etc) to help offset this possibility. (And of course a good dietary regime that does not encourage gut inflammation which is usually the predecessor to pathogen invasion). > > > > Dr. Jaquelyn McCandless> > > > Dr JM responded on the LDN-Autism forum recently regarding anxiety as a side-effect of LDN. She said that about 30% of the population has celiac disease to some degree, and that celiac is not an all or nothing thing. Therefore, she postulates that, like with autistic kids, there is something going on in the gut with many of us. This would be an allergic response to gluten (in wheat and, I think, rye barley, oats) and possibly casein (milk protein) in the gut and an incomplete digestion of these proteins. The result is a release of semi-digested food polypeptides> > into the blood and brain, where they don't belong, and which act as opiates--they stimulate the autistic kids to act out or to space out! The autistic kids, and the rest of us who have some degree of allergy to gluten and/or casein, are " high " on these incompletely digested molecules. When LDN comes along in the blood stream and blocks the opiate effect, we get anxious.> > > > So Dr JM absolutely recommends addressing diet first with autistic kids, but also with others who have problems acclimating to LDN. > > > > posted by > > > > There have been approx. 40 plus instances on the many various LDN forums where LDN caused severe increased pain and the person later found out they had been misdiagnosed and actually were suffering from chronic lyme. LDN can cause increase in pain in those with lyme and LDN can also bring chronic lyme to the forefront, are these herx's, no one knows. Many times a person with lyme will have to stop taking LDN and get proper lyme treatment for 3 to 4 or more months and then later try to re-introduce the LDN back into the mix. Some succeed to continue to take LDN while getting Lyme treatment.> > > > Lyme mimics so many autoimmune system illnesses> > http://ldn.proboards.com/index.cgi?board=links & action=display & thread=926> > > > , LDN user over 7 yrs for chronic progressive MS, dx'd 1989, I started on 4.5mg nightly and I continue to take 4.5mg nightly. I experienced extra stiffness for 3 months, numb hands for 3 weeks and muscle twitching off and on for 6 months but all that faded away as my body adjusted to the LDN endorphin boost. The extra symptoms kicked in around the second and 3rd weeks on LDN. Been in remission for 7yrs on LDN.> >>

[Guest guest]

Happy New Year Everyone, I found this comment intriguing.'I personally

have combined prednisone (40mg) with LDN and found it more beneficial

than just taking steroids on its own. Dr Lawrence is my LDN

prescribing Dr so in my view, I don’t think you have anything to be

scared of.'. My doctor told me to stop prednisone (25mg) and Cellcept before starting LDN. I am taking 4.5 mg of pred with my LDN because I couldn't get any lower without being sick. My doc thinks I'm off the pred and I was worried about it.LDN works great on me and I am in better condition than I have been in since getting sick.Someone recently commented that LDN is not a stand alone treatment.What other treatments mix well with LDN? I would so like to improve to a point

whre I could drive a car and go places without supervision.rocket

[Guest guest]

Jayne,

Some people could be actually harming themselves by doing say double dosing,

taking much more LDN that has been recommended by the researching physicians and

scientists or taking LDN twice a day.

Too much LDN could cause cancer to grow, cause multiple sclerosis to worsen(a

clinical trial done many moons ago of higher dose naltrexone was done on MS and

it caused the disease to progress/worsen), we can't just go overboard on all

these new experiments, especially those who have just started LDN and have only

been doing their out of the box experimenting for a few days, weeks or months.

How about the experiment be of 5, 6, 7 years or more in duration and then if

they have succeeded, well okay then but we have to be carefull and remember to

tell people to experiment with double dosing and other out of the box LDN

experiments at their own risk. Encouraging people to experiment could prove

detrimental to one's health and then LDN starts getting a bad rap. We can go

too far with experimenting with LDN, soon, with some of these experiments it

becomes high dose LDN, dangerous to many of the diseases people are taking LDN

for and we will eventually ruin all the good work we've done getting LDN out in

the medical world and as recognized as it is but if experiments cause disease

progression or death then we lose everything we've gained.

, LDN user 7yrs for progressive MS

===================

===================

==============

>

New evidence about this wonderful treatment we are all taking is appearing all

the time. I think we owe it to ourselves and others to bear this in mind,

especially when someone wants to share they are trying out a new regime, hoping

it may be of benefit to others. Isn't `out of the box' thinking what we all

complain our mainstream Drs aren't doing re LDN? And yet, it does appear when a

LDN user does this by changing their regime, they (as somebody else put it) gets

" pounced on " .

[Guest guest]

, I couldn’t agree with you more re twice a day dosing for cancer and MS. When Donnelly posted the question re a friend with cancer to do this, I was sitting at my computer when that was posted and responded immediately that in my opinion it wouldn’t work for cancer. I also posted my opinion about twice a day dosing (see message #99279) of which I do not support this protocol for MS either. However as mentioned in that post perhaps those who are trying to control inflammation and not getting the desired results from once a day dosing with LDN, twice a day dosing (that doesn’t mean double dosing, but dividing the dose into two) may be of more benefit. There already has been a study done on those with IBS issues which was published in March of last year:- http://www.stlouisgastro.com/client_files/file/Naltrexone-Side-Effects-and-Efficacy-in-GI-Disorders.pdf :- Patients (206) with the following GI conditions were given prescriptions for LDN: IBSwithout evidence for small intestinal bacterial overgrowth (SIBO) (i.e., patients with a normallactulose breath test), IBS with evidence of SIBO (using naltrexone as a second phase oftreatment in efforts to improve motility and reduce inflammation), chronic idiopathicconstipation, and patients with inflammatory bowel disease. Patients with diarrhea were given2.5 mg daily, constipation 2.5 mg twice daily, and inflammatory bowel disease 4.5 mg daily. However, when people initially started taking their LDN in the day and/or alternate days dosing this too wasn’t looked favourable upon and yet they are now enjoying the benefits that we, who take LDN once a day at night do. One thing I know we all try to remember to do is ask what people are taking LDN for before sharing our experiences/opinions. In summary, this twice a day dosing is being researched and I know of one girl in the USA wants to try LDN - her Dr agreed to prescribe LDN and has done so on a twice a day basis. More and more people with varying illnesses other than MS and cancer are trying it where lower doses at less frequent intervals may prove more beneficial. Or the daily amount, split into two. Best, Jayne Crocker www.LDNNow.comImportant! Please sign our LDN petition to the European Parliament by clicking heretel: +44 (0) 7877 492 669Dr Steele MBE, talking about LDNLDNNow are a political/pressure group of individuals dedicated to getting Low Dose Naltrexone (LDN) accepted into modern medicine and trialled for the myriad of uses it shows benefit for. . From: low dose naltrexone [mailto:low dose naltrexone ] On Behalf Of bren_ldnSent: 02 January 2011 02:57low dose naltrexone Subject: [low dose naltrexone] Re: VERY Low Dose Naltrexone Jayne, Some people could be actually harming themselves by doing say double dosing, taking much more LDN that has been recommended by the researching physicians and scientists or taking LDN twice a day.Too much LDN could cause cancer to grow, cause multiple sclerosis to worsen(a clinical trial done many moons ago of higher dose naltrexone was done on MS and it caused the disease to progress/worsen), we can't just go overboard on all these new experiments, especially those who have just started LDN and have only been doing their out of the box experimenting for a few days, weeks or months. How about the experiment be of 5, 6, 7 years or more in duration and then if they have succeeded, well okay then but we have to be carefull and remember to tell people to experiment with double dosing and other out of the box LDN experiments at their own risk. Encouraging people to experiment could prove detrimental to one's health and then LDN starts getting a bad rap. We can go too far with experimenting with LDN, soon, with some of these experiments it becomes high dose LDN, dangerous to many of the diseases people are taking LDN for and we will eventually ruin all the good work we've done getting LDN out in the medical world and as recognized as it is but if experiments cause disease progression or death then we lose everything we've gained., LDN user 7yrs for progressive MS====================================================>New evidence about this wonderful treatment we are all taking is appearing all the time. I think we owe it to ourselves and others to bear this in mind, especially when someone wants to share they are trying out a new regime, hoping it may be of benefit to others. Isn't `out of the box' thinking what we all complain our mainstream Drs aren't doing re LDN? And yet, it does appear when a LDN user does this by changing their regime, they (as somebody else put it) gets " pounced on " .

[Guest guest]

Oops, forgot to post this to the group, as well:

Hi ladies,

What a great email - thanks for the info, Jayne. I haven't been on LDN long,

but I've known of it for years. Now that I'm on it, I'm taking all fo the info

I can get to learn about it. Your comments:

LDN will only work if you follow a particular diet regime

once you’re on LDN, you cannot and must not take any other meds

you need to get up to 4.5mg to reap full benefits

it will take 18 months before you even start to see any benefits with LDN

have posed two questions for me: at what minimum dose can you reap full

benefits, and at what point will you start to see benefits? I've asked that

last one of the group a couple of times, but it has gone unanswered.

As for the HC and adrenals, it actually works like this: the adrenals produce

cortisol, the hormone that helps us handle stress. Under times of stress (from

any source - emotional, physical (including bad diet, allergies, car accident,

public speaking, etc), the adrenals pump out lots of cortisol so that we can

handle the load. For some, and this is my case, that stress is a constant and

never stops, therefore the adrenals get to a point where they can't keep up with

the demand for cortisol, and they shut down. (This can also, as in my case,

cause thyroid problems, as well, as the two work hand in hand.) The theory

behind supplementing with HC is that it will allow the adrenals to rest and

heal, and eventually, hopefully, if the stressors are severely reduced or

elimated, the adrenals will be able to take over once again. Many think that

supplementing with HC will shut down the adrenals completely, and it can;

however, it's believed that that will happen if the supplementing is occuring at

an extremely high dose.

So, that's why, for me, it's extremely important that I heal my gut, as that has

been the one absolute source of stress for me. And it's a vicious cycle,

because the leaky gut and Crohn's are one source of stress, and then the effects

of that - the inflammation, food intolerances and allergies - are yet

another...and it just continues from there. Hence my wish for the LDN to help

out, and I'm really hopeful that it will help with the inflammation that I've

got going on from the Leaky Gut. Hooo boy.

Rocket, I'm sorry that your doc told you to stop the Pred. I know the fear

you're speaking of...I get anxious at the thought of having to stop my HC

because I know what that would do. I hope you feel some relief in knowing that

you're okay, and don't have to stop it. Maybe just let your doc know that

you've done research and you're comfortable with staying at the dose you're at

while on the LDN. I've learned to do that with a lot of my docs, because they

just don't get it. We spend so much time researching our conditions, and they

don't. Unfortunately. Sure would be great if they would/could!

Here's to a healing 2011!

Tara

>

> Dr Bob Lawrence was referring to any dose of steroids in that particular

> statement. Even in the summer when I reluctantly had to go on steroids at

> that dose, he was against this. He is very anti steroids no doubt about it,

> aren't we all? Unfortunately some times if you're that ill, LDN and

> antioxidants just aren't enough and one is then put into a very unfortunate

> position where you have to weigh everything up and make a decision - even

> ones we don't favour. During the past year a number of patients of Dr

> Lawrence have had to combine the two and reported benefits by doing so. I

> believe using LDN as a biotherapy when the going gets tough is currently his

> way of thinking and taking steroids with LDN certainly won't do you any

> harm.

>

>

>

> I think it's a crying shame that people are put off starting LDN to better

> their health when their impressions are:-

>

>

>

> LDN will only work if you follow a particular diet regime

>

> once you're on LDN, you cannot and must not take any other meds

>

> you need to get up to 4.5mg to reap full benefits

>

> it will take 18 months before you even start to see any benefits with LDN

>

>

>

> I know the above isn't what has actually been said, but for some reason this

> is how it's being perceived and shared, therefore putting a stop to others

> looking into LDN.

>

>

>

> New evidence about this wonderful treatment we are all taking is appearing

> all the time. I think we owe it to ourselves and others to bear this in

> mind, especially when someone wants to share they are trying out a new

> regime, hoping it may be of benefit to others. Isn't 'out of the box'

> thinking what we all complain our mainstream Drs aren't doing re LDN? And

> yet, it does appear when a LDN user does this by changing their regime, they

> (as somebody else put it) gets " pounced on " .

>

>

>

> LDN is the ideal combination therapy as it does NOT conflict with anything

> else apart from opiates.

>

>

>

> Tara, from what I've been looking at, the reason you take HC for adrenal

> fatigue is because it is the kidneys that make HC in the body normally. If

> you have adrenal fatigue you are taking it to make up for the loss of HC in

> your own system. The risk here, from what I've been reading is that you may

> possibly make the problem worse because your kidneys will not make HC if you

> are providing it from outside. Therefore I don't think there's any problem

> taking LDN with HC and they do NOT conflict.

>

>

>

> One of the most damaging thing to LDN, is that we make out LDN is an

> exclusive therapy. We want Doctors to add it to their toolbox and want them

> to combine it with other meds that they are use to prescribing. There is no

> problem with this and they will accept its use more readily in modern

> medicine if they can combine it with others.

>

>

>

> Jayne Crocker

>

> LDNNow logo the one to use

>

>

>

> www.LDNNow.com

>

> <http://www.ipetitions.com/petition/ldnnow/> Important! Please sign our

> LDN petition to the European Parliament by clicking here

>

> tel: +44 (0) 7877 492 669

>

> <

Dr Steele MBE, talking

> about LDN

>

> LDNNow are a political/pressure group of individuals dedicated to getting

> Low Dose Naltrexone (LDN) accepted into modern medicine and trialled for the

> myriad of uses it shows benefit for.

>

> .

>

[Guest guest]

For those with MS, taking LDN twice in 1 day may actually cause the disease to

worsen in the long run, until studies are done longterm for 5 years or more of

twice a day dosing for MS, it is more than likely best to not recommend twice a

day dosing for those with MS even if it does make them feel better. Ten or more

years down the road a person could find their MS has actually progressed instead

of halted. IBS and MS are two very different diseases and may need to be

treated by LDN differently from one another. I always tell someone experimenting

with LDN out of the box to do so at their own risk but don't blame LDN if it all

goes wrong.

LDN user 7 1/2 years for chronic progressive MS.

[Guest guest]

, I am not recommending twice a day dosing for MS, because MS is the wrong idea for this approach. IBD however, seems to respond to the naltrexone itself so I believe that is the theory (whilst I am getting it confirmed). So a twice a day regime may be applicable to those scenarios but I am not personally recommending it for MS – glad we agree. Let’s all remember, this is not an MS forum, but a LDN forum where we are discussing an ever growing range of scenarios use of LDN. Thank you. Jayne Crocker www.LDNNow.comImportant! Please sign our LDN petition to the European Parliament by clicking heretel: +44 (0) 7877 492 669Dr Steele MBE, talking about LDNLDNNow are a political/pressure group of individuals dedicated to getting Low Dose Naltrexone (LDN) accepted into modern medicine and trialled for the myriad of uses it shows benefit for. . From: low dose naltrexone [mailto:low dose naltrexone ] On Behalf Of bren_ldnSent: 02 January 2011 19:59low dose naltrexone Subject: [low dose naltrexone] Re: VERY Low Dose Naltrexone For those with MS, taking LDN twice in 1 day may actually cause the disease to worsen in the long run, until studies are done longterm for 5 years or more of twice a day dosing for MS, it is more than likely best to not recommend twice a day dosing for those with MS even if it does make them feel better. Ten or more years down the road a person could find their MS has actually progressed instead of halted. IBS and MS are two very different diseases and may need to be treated by LDN differently from one another. I always tell someone experimenting with LDN out of the box to do so at their own risk but don't blame LDN if it all goes wrong. LDN user 7 1/2 years for chronic progressive MS.

[Guest guest]

Jayne,Thank you for your insight and your positive outlook about looking "outside the box." I am taking LDN during the day and for me it seems to be helping. Dr. Zagon told me I could take it during the day and I could also take it on an empty stomach or with food. I know it is giving me some benefit because I am not as fatigued and my fibro and connective tissue pain seems to be lessened. Thanks.....it is hard to be a firm follower of a certain regime if when you take it you cannot sleep and you feel sick.From: jaynelcrocker <jaynelcrocker@...>low dose naltrexone Sent: Sat, January 1, 2011 11:11:00 AMSubject: RE: [low dose naltrexone] Re: VERY Low Dose Naltrexone Dr Bob Lawrence was referring to any dose of

steroids in that particular statement. Even in the summer when I reluctantly had to go on steroids at that dose, he was against this. He is very anti steroids no doubt about it, aren’t we all? Unfortunately some times if you’re that ill, LDN and antioxidants just aren’t enough and one is then put into a very unfortunate position where you have to weigh everything up and make a decision - even ones we don’t favour. During the past year a number of patients of Dr Lawrence have had to combine the two and reported benefits by doing so. I believe using LDN as a biotherapy when the going gets tough is currently his way of thinking and taking steroids with LDN certainly won’t do you any harm. I think it’s a crying shame that people are put off starting LDN to better their

health when their impressions are:- LDN will only work if you follow a particular diet regimeonce you’re on LDN, you cannot and must not take any other meds you need to get up to 4.5mg to reap full benefitsit will take 18 months before you even start to see any benefits with LDN I know the above isn’t what has actually been said, but for some reason this is how it’s being perceived and shared, therefore putting a stop to others looking into LDN. New evidence about this wonderful treatment we are all taking is appearing all the time. I think we owe it to ourselves and others to bear this in mind, especially when someone wants to share they are trying out a new regime, hoping it may be of benefit to others. Isn’t ‘out of the box’ thinking what we all complain our mainstream Drs aren’t doing re LDN? And yet, it does appear when a LDN user does this by changing their regime, they (as somebody else put it) gets “pounced onâ€. LDN is the ideal combination therapy as it does NOT conflict with anything else apart from opiates. Tara, from what I’ve been looking at, the reason you take HC for adrenal fatigue is because it is the kidneys that make HC in the body normally. If you have adrenal fatigue you are taking it to make up for the loss of HC in your own system. The risk here, from what I’ve been reading is that you may possibly make the problem worse because your kidneys will not make HC if you are providing it from outside. Therefore I don’t think there’s any problem taking LDN with HC and they do NOT conflict. One of the most damaging thing to LDN, is that we make out LDN is an exclusive therapy. We want Doctors to add it to their toolbox and want them to combine it with other meds that they are use to prescribing. There is no problem with this and they will accept its use more readily in modern medicine if they can combine it with others. Jayne CrockerLDNNow logo the one to use"> www.LDNNow.comImportant! Please sign our LDN petition to the European Parliament by clicking heretel: +44 (0) 7877 492 669Dr Steele MBE, talking about

LDNLDNNow are a political/pressure group of individuals dedicated to getting Low Dose Naltrexone (LDN) accepted into modern medicine and trialled for the myriad of uses it shows benefit for. . From: low dose naltrexone [mailto:low dose naltrexone ] On Behalf Of bren_ldnSent: 01 January 2011 02:49low dose naltrexone Subject: [low dose naltrexone] Re: VERY Low Dose Naltrexone he's referring to heavy steroids==============================> >> > > > For those of you in the first 3 to 6 months of LDN therapy, you may experience temporarilly extra stiffness, headache, numbness, vertigo, sleeplessness, diuretic effect, loss of appetite, extra fatigue, etc.> > > > Below is by Dr. Bob Lawrence who takes LDN himself> > > > When starting this LDN(Low Dose Naltrexone) therapy in the treatment of autoimmune illness, there may also be some initial transient, though temporary, increase in symptoms. > > > > Experience in using this method has demonstrated most commonly, such as disturbed sleep, occasionally with vivid, bizarre and disturbing dreams, tiredness, fatigue, spasm and pain. > > > >

Rarely, other transient symptoms have included more severe pain and spasm, headache, diarrhea or vomiting. These additional symptoms would appear to be associated with the previous frequent use of strong analgesics, which effectively create an addiction and dependency, thus increasing the body's sensitivity to pain. > > > > In addition, because LDN stimulates the immune system and many of the drugs routinely used by the NHS in the treatment of MS and autoimmune disease further suppress the immune system, LDN cannot be used in company with steroids, beta interferon, methotrexate, azathioprine or mitozantrone or any other immune suppressant drug. If there is any doubt, please submit a full list of the drugs you are presently taking so that their compatibility may be assessed. > > > > In addition, because LDN will also block the analgesic effects of any opiate drugs (includes codeine, dihydrocodeine, morphine,

pethidine or diamorphine) presently being taken, the use of LDN will initially greatly increase the level of pain experienced. It is therefore advisable that any opiate-like drugs be discontinued at least two weeks before this treatment is initiated. When starting the treatment it is essential that any untoward or adverse side-effects are reported immediately so that the treatment process can be further assessed and, if necessary, modified. > > ============> > Below is by Dr. Jaquelyn McCandless> > Other reasons of negative responses to LDN by Dr. Jaquelyn McCandless> > > > Re: ldn > > > > As usual, I need to emphasize that seldom is LDN a stand-alone treatment, but accompanies other strategies their body needs, especially a healthy diet. No sugar, dairy or gluten.> > > > It takes some people longer to respond to LDN, and they may be colonized with pathogenic yeast

and bacteria that could be slowing response.> > > > There is a phenomenon that happens to some people that as the immune system is shifting (usually from T2 to T1) right after starting LDN, the immune system drops and people get an infection, cold, flu, cold sore, etc. which is usually short lived. Candida tends to overgrow or a virus will flare up. These infections are usually short-lived unless something like candida and gut bacteria needs treatment. > > > > Are you a big bread/carbohydrate/sugar eater? > > Ever been tested for candida (yeast) or gut bacterial infestation? > > Ever been checked for hypothyroidism? > > > > Would you be willing to stop all casein (milk products) and gluten (wheat, rye, barley and oats) for a week and see if you feel better? A study done several years ago showed that 30% of us have some degree of celiac disease (intolerance/allegy to wheat)

even though the clinical symptoms may not be obvious enough to alert most people to that. When anyone in that 30% of persons stops eating wheat, they feel a lot better. The LDN may be acting like the opioid antagonist it is and causing a withdrawal reaction from taking away your fix, even if only for a few hours.> > > > Try to hang in for awhile longer, and it will probably get better. These setbacks usually do not last long unless something like a yeast infection is stubborn without specific treatment. > > Dr. JM> > =====> > > > Q: Dr. JM or anyone- Does LDN cause candida? > > > > A: LDN has been noted to aggravate yeast infections and other latent pathogens, viruses, etc. as the immune system is making early adjustments. It is good to have natural yeast remedies on board when LDN is started (grapefruit seed extract, Candex, lauricidin, hi-potency probiotics, etc) to help

offset this possibility. (And of course a good dietary regime that does not encourage gut inflammation which is usually the predecessor to pathogen invasion). > > > > Dr. Jaquelyn McCandless> > > > Dr JM responded on the LDN-Autism forum recently regarding anxiety as a side-effect of LDN. She said that about 30% of the population has celiac disease to some degree, and that celiac is not an all or nothing thing. Therefore, she postulates that, like with autistic kids, there is something going on in the gut with many of us. This would be an allergic response to gluten (in wheat and, I think, rye barley, oats) and possibly casein (milk protein) in the gut and an incomplete digestion of these proteins. The result is a release of semi-digested food polypeptides> > into the blood and brain, where they don't belong, and which act as opiates--they stimulate the autistic kids to act out or to space out! The

autistic kids, and the rest of us who have some degree of allergy to gluten and/or casein, are "high" on these incompletely digested molecules. When LDN comes along in the blood stream and blocks the opiate effect, we get anxious.> > > > So Dr JM absolutely recommends addressing diet first with autistic kids, but also with others who have problems acclimating to LDN. > > > > posted by > > > > There have been approx. 40 plus instances on the many various LDN forums where LDN caused severe increased pain and the person later found out they had been misdiagnosed and actually were suffering from chronic lyme. LDN can cause increase in pain in those with lyme and LDN can also bring chronic lyme to the forefront, are these herx's, no one knows. Many times a person with lyme will have to stop taking LDN and get proper lyme treatment for 3 to 4 or more months and then later try to re-introduce

the LDN back into the mix. Some succeed to continue to take LDN while getting Lyme treatment.> > > > Lyme mimics so many autoimmune system illnesses> > http://ldn.proboards.com/index.cgi?board=links & action=display & thread=926> > > > , LDN user over 7 yrs for chronic progressive MS, dx'd 1989, I started on 4.5mg nightly and I continue to take 4.5mg nightly. I experienced extra stiffness for 3 months, numb hands for 3 weeks and muscle twitching off and on for 6 months but all that faded away as my body adjusted to the LDN endorphin boost. The extra symptoms kicked in around the second and 3rd weeks on LDN. Been in remission for 7yrs on LDN.> >>

[Guest guest]

Yes let's recall that the doctors with thousands of patients between them

have said that, especially with MS, symptom relief is a nice benefit but

not the first goal. The first goal is to stop disease progression, and we

already know that the traditional, once a day dosing is what stops MS

progression. To me, the protocol for MS is very well established.

--

At 01:58 PM 1/2/2011, you wrote:

>For those with MS, taking LDN twice in 1 day may actually cause the

>disease to worsen in the long run, until studies are done longterm for 5

>years or more of twice a day dosing for MS, it is more than likely best to

>not recommend twice a day dosing for those with MS even if it does make

>them feel better. Ten or more years down the road a person could find

>their MS has actually progressed instead of halted. IBS and MS are two

>very different diseases and may need to be treated by LDN differently from

>one another. I always tell someone experimenting with LDN out of the box

>to do so at their own risk but don't blame LDN if it all goes wrong.

>

> LDN user 7 1/2 years for chronic progressive MS.

>

>

>

>------------------------------------

>

>

[Guest guest]

, It is the Drs with patients on LDN who are now prescribing the twice a day dosing, not patients doing it off their own back and/or experimenting which is being implied. Also, for some with MS, every other day dosing is proving just as effective if not more for those who have been on it for some time. You just need to ask Dr Bob Lawrence who has been taking LDN for his MS for 10 years and/or Dr Zagon from his research. So please, let’s not forget that or try to make ourselves the voices of authority over a Doctor’s advice. Jayne Crocker www.LDNNow.comImportant! Please sign our LDN petition to the European Parliament by clicking heretel: +44 (0) 7877 492 669Dr Steele MBE, talking about LDNLDNNow are a political/pressure group of individuals dedicated to getting Low Dose Naltrexone (LDN) accepted into modern medicine and trialled for the myriad of uses it shows benefit for. . From: low dose naltrexone [mailto:low dose naltrexone ] On Behalf Of BakerSent: 02 January 2011 23:27low dose naltrexone Subject: Re: [low dose naltrexone] Re: VERY Low Dose Naltrexone Yes let's recall that the doctors with thousands of patients between them have said that, especially with MS, symptom relief is a nice benefit but not the first goal. The first goal is to stop disease progression, and we already know that the traditional, once a day dosing is what stops MS progression. To me, the protocol for MS is very well established.--At 01:58 PM 1/2/2011, you wrote:>For those with MS, taking LDN twice in 1 day may actually cause the >disease to worsen in the long run, until studies are done longterm for 5 >years or more of twice a day dosing for MS, it is more than likely best to >not recommend twice a day dosing for those with MS even if it does make >them feel better. Ten or more years down the road a person could find >their MS has actually progressed instead of halted. IBS and MS are two >very different diseases and may need to be treated by LDN differently from >one another. I always tell someone experimenting with LDN out of the box >to do so at their own risk but don't blame LDN if it all goes wrong.>> LDN user 7 1/2 years for chronic progressive MS.>>>>------------------------------------>>

[Guest guest]

Thanks Tara and for your comment re HC and Adrenals, so much to learn so appreciate what you’ve shared. Re your question have posed two questions for me: at what minimum dose can you reap full benefits, and at what point will you start to see benefits? The only answer I can personally come up with is ‘everyone is different’ which I know is beginning to sound like a chorus line here.  I started at 3mg, then 3.7mg and then 4.5mg and went down to 3mg for my IBD issues. In 2009 Boyle Bradley did a blogtalk show radio re LDN and had the founder/researcher of LDN on her show – Dr Ian Zagon.  According to Dr Zagon in this interview one had to take a minimum of 1.75mg in order to reap any benefits of LDN.  This is posted on the LDNNow blog which was edited by Elaine (The Promise of Low Dose Naltrexone) and confirmed by Dr Ian Zagon http://www.ldnnow.co.uk/8601.html?interval=2009-06 Hope this helps. Jayne Crocker www.LDNNow.comImportant! Please sign our LDN petition to the European Parliament by clicking heretel: +44 (0) 7877 492 669Dr Steele MBE, talking about LDNLDNNow are a political/pressure group of individuals dedicated to getting Low Dose Naltrexone (LDN) accepted into modern medicine and trialled for the myriad of uses it shows benefit for. . From: low dose naltrexone [mailto:low dose naltrexone ] On Behalf Of tcopatSent: 02 January 2011 18:17low dose naltrexone Subject: [low dose naltrexone] Re: VERY Low Dose Naltrexone Oops, forgot to post this to the group, as well:Hi ladies,What a great email - thanks for the info, Jayne. I haven't been on LDN long, but I've known of it for years. Now that I'm on it, I'm taking all fo the info I can get to learn about it. Your comments:LDN will only work if you follow a particular diet regimeonce you’re on LDN, you cannot and must not take any other medsyou need to get up to 4.5mg to reap full benefitsit will take 18 months before you even start to see any benefits with LDNhave posed two questions for me: at what minimum dose can you reap full benefits, and at what point will you start to see benefits? I've asked that last one of the group a couple of times, but it has gone unanswered.As for the HC and adrenals, it actually works like this: the adrenals produce cortisol, the hormone that helps us handle stress. Under times of stress (from any source - emotional, physical (including bad diet, allergies, car accident, public speaking, etc), the adrenals pump out lots of cortisol so that we can handle the load. For some, and this is my case, that stress is a constant and never stops, therefore the adrenals get to a point where they can't keep up with the demand for cortisol, and they shut down. (This can also, as in my case, cause thyroid problems, as well, as the two work hand in hand.) The theory behind supplementing with HC is that it will allow the adrenals to rest and heal, and eventually, hopefully, if the stressors are severely reduced or elimated, the adrenals will be able to take over once again. Many think that supplementing with HC will shut down the adrenals completely, and it can; however, it's believed that that will happen if the supplementing is occuring at an extremely high dose. So, that's why, for me, it's extremely important that I heal my gut, as that has been the one absolute source of stress for me. And it's a vicious cycle, because the leaky gut and Crohn's are one source of stress, and then the effects of that - the inflammation, food intolerances and allergies - are yet another...and it just continues from there. Hence my wish for the LDN to help out, and I'm really hopeful that it will help with the inflammation that I've got going on from the Leaky Gut. Hooo boy. :)Rocket, I'm sorry that your doc told you to stop the Pred. I know the fear you're speaking of...I get anxious at the thought of having to stop my HC because I know what that would do. I hope you feel some relief in knowing that you're okay, and don't have to stop it. Maybe just let your doc know that you've done research and you're comfortable with staying at the dose you're at while on the LDN. I've learned to do that with a lot of my docs, because they just don't get it. We spend so much time researching our conditions, and they don't. Unfortunately. Sure would be great if they would/could! :)Here's to a healing 2011!Tara>> Dr Bob Lawrence was referring to any dose of steroids in that particular> statement. Even in the summer when I reluctantly had to go on steroids at> that dose, he was against this. He is very anti steroids no doubt about it,> aren't we all? Unfortunately some times if you're that ill, LDN and> antioxidants just aren't enough and one is then put into a very unfortunate> position where you have to weigh everything up and make a decision - even> ones we don't favour. During the past year a number of patients of Dr> Lawrence have had to combine the two and reported benefits by doing so. I> believe using LDN as a biotherapy when the going gets tough is currently his> way of thinking and taking steroids with LDN certainly won't do you any> harm.> > > > I think it's a crying shame that people are put off starting LDN to better> their health when their impressions are:-> > > > LDN will only work if you follow a particular diet regime> > once you're on LDN, you cannot and must not take any other meds > > you need to get up to 4.5mg to reap full benefits> > it will take 18 months before you even start to see any benefits with LDN> > > > I know the above isn't what has actually been said, but for some reason this> is how it's being perceived and shared, therefore putting a stop to others> looking into LDN.> > > > New evidence about this wonderful treatment we are all taking is appearing> all the time. I think we owe it to ourselves and others to bear this in> mind, especially when someone wants to share they are trying out a new> regime, hoping it may be of benefit to others. Isn't 'out of the box'> thinking what we all complain our mainstream Drs aren't doing re LDN? And> yet, it does appear when a LDN user does this by changing their regime, they> (as somebody else put it) gets " pounced on " . > > > > LDN is the ideal combination therapy as it does NOT conflict with anything> else apart from opiates. > > > > Tara, from what I've been looking at, the reason you take HC for adrenal> fatigue is because it is the kidneys that make HC in the body normally. If> you have adrenal fatigue you are taking it to make up for the loss of HC in> your own system. The risk here, from what I've been reading is that you may> possibly make the problem worse because your kidneys will not make HC if you> are providing it from outside. Therefore I don't think there's any problem> taking LDN with HC and they do NOT conflict.> > > > One of the most damaging thing to LDN, is that we make out LDN is an> exclusive therapy. We want Doctors to add it to their toolbox and want them> to combine it with other meds that they are use to prescribing. There is no> problem with this and they will accept its use more readily in modern> medicine if they can combine it with others. > > > > Jayne Crocker> > LDNNow logo the one to use> > > > www.LDNNow.com> > <http://www.ipetitions.com/petition/ldnnow/> Important! Please sign our> LDN petition to the European Parliament by clicking here> > tel: +44 (0) 7877 492 669> > <

Dr Steele MBE, talking> about LDN> > LDNNow are a political/pressure group of individuals dedicated to getting> Low Dose Naltrexone (LDN) accepted into modern medicine and trialled for the> myriad of uses it shows benefit for. > > .>

[Guest guest]

You have to do saliva test for cortisol x4 over the day to

see how fatigue are your adrenals.

Usually 20-30 mg hc will do it.

you have to learn to use stress dosing

I am using the Free version of SPAMfighter.SPAMfighter has removed 1726 of my spam emails to date.Do you have a slow PC? Try free scan!

[Guest guest]

I have a question. I have been taking LDN since Oct. I have lost weight without

even trying and also have hot flashes is this due to LDN or am I just having a

hormonal crisis??

RE: [low dose naltrexone] Re: VERY Low Dose Naltrexone

 

You have to do saliva test for cortisol x4 over the day to see how fatigue are

your adrenals.

 

Usually 20-30 mg hc will do it.

you have to learn to use stress dosing

I am using the Free version of SPAMfighter .

SPAMfighter has removed 1726 of my spam emails to date.

Do you have a slow PC? Try free scan!

[Guest guest]

Many have experienced weightloss on LDN.

, LDN user over 7 yrs

====================

>

> I have a question. I have been taking LDN since Oct. I have lost weight

without even trying and also have hot flashes is this due to LDN or am I just

having a hormonal crisis??

> RE: [low dose naltrexone] Re: VERY Low Dose Naltrexone

>

>  

>

>

>

>

>

>

>

> You have to do saliva test for cortisol x4 over the day to see how fatigue are

your adrenals.

>

>  

>

> Usually 20-30 mg hc will do it.

>

> you have to learn to use stress dosing

>

> I am using the Free version of SPAMfighter .

> SPAMfighter has removed 1726 of my spam emails to date.

>

> Do you have a slow PC? Try free scan!

>