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hypogammaglobulinemia

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>I told immunologist about this list since I was looking for info regarding low

IGM. She asked if there were any children on list with it. She has only seen 4

others in Tch with lowIGM and said it's very rare and they don't have much info

on it.

>

from Dale,

Margie, my daughter has low IgG, low IgA, low IgM, low IgD, low IgE --

across the board. What we were told is that IgM is a precursor to IgG

and IgA. In other words, the B-cells make IgM and then IgM becomes

either IgG or IgA -- whichever one the body needs worse. So, if the

IgG or IgA is low -- it will deplete the IgM. But when we gave her IVIG

-- which replaces the IgG she remained low on IgA and IgM. Maybe

because her IgA is so low.

There is a condition where the IgM is high, but as far as I know there's

not a lot of documentation on it being low. So, I can't help you

except to say that, yes, it does happen!

In His service,

Dale

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I do know that When Blake was first tested at age 3 his IgM was

low. IT had always showed up low when he was tested several times.

When he started IVIG he was 6yrs. old. His Igm was <5. This is low.

When he started IVIG, after the first does they did a level & it was

noted as not even detectable.

Blake does IVIG every 2 weeks(15grams Gammagard). His Immuno has ALL

levels drawn once every 6 months. each time it is still

undetectable!!!

Hope this helps!

As far as IgA oges this too is " undetectable " , His last IgG was 657

(951-1700).

Mom to Blake 13, (my Adventure of a LifeTime.......constantly

testing my nerves!! I think the only reason he sleeps these days is

to see what kinds of trouble he can get into & get a way with!!!!)

http://www3.org/sc/blakester

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

> Hi,

> I have posted in a couple of month. I just wanted to post since

Zachary saw the immunologist Friday for repeat IGG, subclasses,

humon panel, ch 50 and other stuff-

> They gave him the pneumoccal vaccine since they said he only

reponded to slightly 3 last time. Whatever that meant. They said

they recheck 10-28 to see if vaccine took.

> I told immunologist about this list since I was looking for info

regarding low IGM. She asked if there were any children on list with

it. She has only seen 4 others in Tch with lowIGM and said it's very

rare and they don't have much info on it. He has been ok this summer

just the usual sinus infection, but he's been tired since August. I

thought maybe the allegra so we switched to singular today.

> I was hoping for some imput of questions I should ask on 10-28.

Also they Dr. said she was concerned with this humoral panel..

> I have 435 emails to read-been along time since I've read the list.

> laughter and sunshine,

> Margie

>

> .

>

>

> ---------------------------------

> for Good

> Click here to donate to the Hurricane Katrina relief effort.

>

>

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Christian, my son, has low IgG and low IgM... IgA is fine We were

originally told he had THI but we're waiting for the latest batch of

blood tests to be analyzed. I'll find more out once the immunologist

gets in touch with us.

I also recently learned his body did not accept the tetanus vaccine.

>

> >I told immunologist about this list since I was looking for info

regarding low IGM. She asked if there were any children on list with

it. She has only seen 4 others in Tch with lowIGM and said it's very

rare and they don't have much info on it.

> >

> from Dale,

>

> Margie, my daughter has low IgG, low IgA, low IgM, low IgD, low

IgE --

> across the board. What we were told is that IgM is a precursor to

IgG

> and IgA. In other words, the B-cells make IgM and then IgM

becomes

> either IgG or IgA -- whichever one the body needs worse. So, if

the

> IgG or IgA is low -- it will deplete the IgM. But when we gave

her IVIG

> -- which replaces the IgG she remained low on IgA and IgM. Maybe

> because her IgA is so low.

>

> There is a condition where the IgM is high, but as far as I know

there's

> not a lot of documentation on it being low. So, I can't help you

> except to say that, yes, it does happen!

>

> In His service,

> Dale

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  • 4 years later...

>

> Dear Bee & folks,

>

> I will soon be beginning Bee's anti-candida diet, but at the moment I am still

studying [and I haven't gone to the store yet. : ) ]

>

> I have a friend who is often very sick and it takes him a while to overcome

any cold or flu. I believe this diet works, but according to his doctors he was

born with hypogammaglobulinemia. This disorder is seemingly caused by a lack of

a gene that helps to resist infection (according to his doctor). It seems to me

that Bee's diet is exactly what he needs, but I wonder about the " lack " of a

gene?

+++Hi . It amazes me at the very complicated and long names the medical

field creates! You can be reassured that proper nutrition plus eliminating

toxins and damaging foods will correct any DNA/genes a person acquires from

their parents. Dr. Weston A. Price writes about this a lot - his book is

Nutrition and Physical Degeneration.

>

> His siblings and mother are also super sensitive to vitamin C and any

probiotics (which cause vomiting/diahrrea). They also have this disorder.

+++Of course vitamin C can cause healing reactions like that, so the answer is

to start with small amounts taken with complete meals containing meats or eggs

and good fats, and slowly increase the amounts. I don't think probiotics are

good anyway, so I'm eliminating them from my program - I'm still re-writing my

article.

All the best, Bee

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  • 8 months later...

Switching brands often solves the problem of reactions. The exception

has to do with IgA antibodies which is one reason doctors do labs

testing for IgA. Doctors, infusion nurses, and providing pharmacies

should be familiar with this issue as well as possible reactions and

should be ready to deal with any reaction.

Pat

On 10/1/10, Ellen <rhudy@...> wrote:

> Found this interesting page from Wikipedia...............look at

> " Reactions, " it says that switching brands of IVIG may be problematical.

>

> http://en.wikipedia.org/wiki/Common_variable_immunodeficiency

> Ellen

>

>

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  • 3 months later...

Has anyone in this group ever heard of hypogammaglobulinemia? Several years ago I had lab tests done by a neurologist for upper back, neck and head pain. Actually, I needed to see a neurosurgeon according to the neuro. She ordered several tests and while recently looking through some of my lab work when cleaning out file cabinets found "Mild hypogammaglobulinemia" and the test for Vitamin B12 result was 1011 [flagged] - the Ranges 180-914. Nothing was mentioned about the tests at the time other than some comment related to the Vitamin B12.

The tests were done because I'd had two spinal fusions for congenital spondylolythesis and when I began having neck and back pain, along with headaches decided to see a neurologist who ordered a lot of lab work.

I checked with Google and much information came up but I would like to hear from someone who can`comment on the Mild hypogammaglobulinemia, especially someone who may have been diagnosed with it; it appears to be a disorder?

Thanks for any information.

Ginny

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  • 2 months later...
Guest guest

Sounds like classic CVID, treatment is IVIG. It can be a scary prospect at 1st

but it will really slow down the rate of illness and keep her from getting so

sick all the time. Illness + FOD is a scary thing and treating the CVID will

help big time. I will say you might want to get her switched to the sub-q method

(you do at home weekly) as soon as possible if you go the IG route so you can

avoid picking up more germs in the hospital and risking crisis with the VLCAD.

(I know you from the FOD group:)

________________________________

From: hessesarah <hessesarah@...>

Sent: Fri, March 11, 2011 9:51:24 AM

Subject: Hypogammaglobulinemia

Ok so i went to my daughters genetics apointment and i found out that the

hemotologist diagnosed her w/ hypogammaglobulinemia . So she has

nuetropenia,hypogammaglobulinemia,and doesnt respond to her titer such as

tetanus,pnuemococi, etc so we are still not sure what the overall diagnoses is

or if it is several different ones but i am waiting for the immunologist to call

me back because she couldnt get us in for an appointment and they are reviewing

her case.

sarah

Dakota 15 months old-VLCAD, nuetropenia,hypogammaglobuinemia,non-responder to

vacc titers etc....

colorado

------------------------------------

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Primary Immune Deficiency. Opinions or medical advice stated here are the sole

responsibility of the poster and should not be taken as professional advice.

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