Re: Update by Dr Jaquelyn McCandless on transdermal LDN/more

[Guest guest]

I am a chilean doctor, nobody here works with LDN and I would like to contact Dr McCandless in order to be mentored, if that is possibleI work with ASD children, but since nobody here has any experience with LDN, it would be really useful to me to contact her

Also, I would also like to know what should I do to get myself  into her autism LDN listThank you in advance CalderonOn 30 December 2010 02:30, bren_ldn <TwisterAlley2@...> wrote:

 

Hi, Art and :

1) The transdermal cream is helping many thousands of children with autism who cannot swallow capsules and cannot use the liquid sweeteners without adding toxins to their already overburdened systems. Not to mention having to wake difficult to get to sleep children to force some bitter substance or a capsule they cannot swallow down them at the time I have found to be most useful (after

9pm, when most of them are actually asleep). My autism LDN list has almost 3000 autism parents on it, and generally the reports are positive - my database of 200 when I started showed 75% indicated overall benefit of LDN for ASD children.

2) In my private clinical study in 2005, in 16 weeks of adding only LDN to their regular routine, 80% of children and 70% of their parents (both groups of whose range of CD4+ cells were normal to begin with) elevated their CD4+ cell count, which inspired me to take this med to Africa for my clinical research to follow-up and conduct the study initially proposed by Dr. Bihari (which could not get funded). The study is almost completed and indeed is showing the ability of LDN to maintain the CD4+ count over the 9month study period in those with

HIV+, and is far better combined with HAART drugs than those drugs alone for persons who already have AIDS. It may be a matter of semantics or wording, and I cannot officially say whether this would be called immune enhancing, modulating, boosting, stimulating, or what, but in my book it means LDN helps the immune system function better.

3) I try to get all of my patients off steroids as soon as possible, and ask them to start lowering them in anticipation of getting off before giving LDN, finding that if I start LDN before they got their dose down I have poor clinical results, and finally found that around 10mg a day the LDN did not interfere with their clinical process, and the great majority of my patients end up not needing steroids once stabilized on the LDN. I would love to see a study showing just what the relationship is, but I am not able to do that myself right now, so this

will be what I do and recommend until further info comes in.

4) With the children, I learned that if I started low, their adjustment period seemed to drag on, whereas if I started with full dose for their weight, the adjustment was short-lived, after which most made good clinical gains. I use 1.5mg to start for kids 30 pounds, 3mg for kids 30-100 pounds, 3.5mg from 100-115 pounds, 4mg from 115-125 pounds, and 4.5mg for 125 pounds, the same as for adults. The only adult patients I start with 3mg are MS patients who have spasticity, using transdermal and raising very slowly as they can tolerate it.

5) I have many Crohn's patients, and find the transdermal works much better in those and all patients with GI issues. It is also much easier to use in the beginning to establish proper dosage.

6) If anyone has a strong persistent negative (more than 7-10 days) reaction to LDN, I rule out the use of casein and gluten in the diet (and particularly in ASD children who are mostly intolerant of these foods) and candida infestation, (often these go together, as immunotoxic foods cause gut inflammation and propensity to pathogen infestation in everyone). A good stool study and a 90-food IgG hypersensitivity test is invaluable in assessing this, and if patients can afford it, a urinary organic acid test helps a lot in seeing what kind of nutrients they need as well as another indication of pathogen invasion. I also always get a Vit D3 level and try to keep all my patients above 70ng/mL, and with the ASD kids, the closer to 100ng/mL the better.

7) I feel LDN is the best anti-aging substance out there, helping energy, libido, and immunity. I and my husband (both just 79 and on it for over 5 years now) and multiple elder friends, family members, and clients who travel and are very busy active productive people swear by it and many say they have gone for years now (as Jack and I have) without colds or other infections. Feel free to share any or all of this on the group, as there seem to be quite a few listers who want to know what I think about these issues. However, please do not refer more people to me, as I am swamped with the patients and projects I already have, including physicians I mentor, and I really want to finish the book I'm writing! If someone really wants my help the best way is to pay for their doctor to consult me, which helps get more docs into LDN. I'm willing to turn them onto the labs I find most helpful and guide them in the clinical use of LDN (and other anti-aging and gut meds). Thanks so much! Jaquelyn

Posted by

-- Dra Calderón GiadrosicMedicina Gral U de ChileTerapia Floraleve@...

[Guest guest]

This is a group for discussing and reporting treatment results with LDN (low

dose naltrexone) in autism spectrum disorder. This is a new treatment and the

goal is to get as much information as possible to help parents decide if this is

an appropriate and safe treatment for their autistic child

Autism_LDN/

--

>

> >

> >

> >

> > Hi, Art and :

> >

> > 1) The transdermal cream is helping many thousands of children with autism

> > who cannot swallow capsules and cannot use the liquid sweeteners without

> > adding toxins to their already overburdened systems. Not to mention having

> > to wake difficult to get to sleep children to force some bitter substance or

> > a capsule they cannot swallow down them at the time I have found to be most

> > useful (after

> > 9pm, when most of them are actually asleep). My autism LDN list has almost

> > 3000 autism parents on it, and generally the reports are positive - my

> > database of 200 when I started showed 75% indicated overall benefit of LDN

> > for ASD children.

> >

> > 2) In my private clinical study in 2005, in 16 weeks of adding only LDN to

> > their regular routine, 80% of children and 70% of their parents (both groups

> > of whose range of CD4+ cells were normal to begin with) elevated their CD4+

> > cell count, which inspired me to take this med to Africa for my clinical

> > research to follow-up and conduct the study initially proposed by Dr. Bihari

> > (which could not get funded). The study is almost completed and indeed is

> > showing the ability of LDN to maintain the CD4+ count over the 9month study

> > period in those with

> > HIV+, and is far better combined with HAART drugs than those drugs alone

> > for persons who already have AIDS. It may be a matter of semantics or

> > wording, and I cannot officially say whether this would be called immune

> > enhancing, modulating, boosting, stimulating, or what, but in my book it

> > means LDN helps the immune system function better.

> >

> > 3) I try to get all of my patients off steroids as soon as possible, and

> > ask them to start lowering them in anticipation of getting off before giving

> > LDN, finding that if I start LDN before they got their dose down I have poor

> > clinical results, and finally found that around 10mg a day the LDN did not

> > interfere with their clinical process, and the great majority of my patients

> > end up not needing steroids once stabilized on the LDN. I would love to see

> > a study showing just what the relationship is, but I am not able to do that

> > myself right now, so this

> > will be what I do and recommend until further info comes in.

> >

> > 4) With the children, I learned that if I started low, their adjustment

> > period seemed to drag on, whereas if I started with full dose for their

> > weight, the adjustment was short-lived, after which most made good clinical

> > gains. I use 1.5mg to start for kids 30 pounds, 3mg for kids 30-100 pounds,

> > 3.5mg from 100-115 pounds, 4mg from 115-125 pounds, and 4.5mg for 125

> > pounds, the same as for adults. The only adult patients I start with 3mg are

> > MS patients who have spasticity, using transdermal and raising very slowly

> > as they can tolerate it.

> >

> > 5) I have many Crohn's patients, and find the transdermal works much better

> > in those and all patients with GI issues. It is also much easier to use in

> > the beginning to establish proper dosage.

> >

> > 6) If anyone has a strong persistent negative (more than 7-10 days)

> > reaction to LDN, I rule out the use of casein and gluten in the diet (and

> > particularly in ASD children who are mostly intolerant of these foods) and

> > candida infestation, (often these go together, as immunotoxic foods cause

> > gut inflammation and propensity to pathogen infestation in everyone). A good

> > stool study and a 90-food IgG hypersensitivity test is invaluable in

> > assessing this, and if patients can afford it, a urinary organic acid test

> > helps a lot in seeing what kind of nutrients they need as well as another

> > indication of pathogen invasion. I also always get a Vit D3 level and try to

> > keep all my patients above 70ng/mL, and with the ASD kids, the closer to

> > 100ng/mL the better.

> >

> > 7) I feel LDN is the best anti-aging substance out there, helping energy,

> > libido, and immunity. I and my husband (both just 79 and on it for over 5

> > years now) and multiple elder friends, family members, and clients who

> > travel and are very busy active productive people swear by it and many say

> > they have gone for years now (as Jack and I have) without colds or other

> > infections. Feel free to share any or all of this on the group, as there

> > seem to be quite a few listers who want to know what I think about these

> > issues. However, please do not refer more people to me, as I am swamped with

> > the patients and projects I already have, including physicians I mentor, and

> > I really want to finish the book I'm writing! If someone really wants my

> > help the best way is to pay for their doctor to consult me, which helps get

> > more docs into LDN. I'm willing to turn them onto the labs I find most

> > helpful and guide them in the clinical use of LDN (and other anti-aging and

> > gut meds). Thanks so much! Jaquelyn

> >

> > Posted by

> >

> >

> >

>

>

>

> --

> Dra Calderón Giadrosic

> Medicina Gral U de Chile

> Terapia Floral

> eve@...

>