Guest guest Posted February 23, 2011 Report Share Posted February 23, 2011 This is a good question and VERY important. There are two different problems. One is that when you take LDN, it will block the receptor sites and the opiate that you take then, will not stop the pain that it is being taken for. If you take just one dose, it probably does clear in just a couple of hours. It needs to, to be able to work properly. It is the rebound that you are looking for to boost the endorphins. So, the worst that will happen is that the pain is not alleviated by the opiate. The bigger problem comes when a person who routinely takes opiates (and therefore is addicted, even if minorly) takes LDN. It will block the receptor sites and that person will not only stop having pain relief, but WILL GO INTO WITHDRAWAL, which is NOT fun and can even be life threatening. A person should be withdrawn from opiates for at least two weeks before even considering taking a single dose of LDN. So, there is a difference between taking LDN and then needing to take a major pain reliever, and a person who uses opiates and then takes LDN afterward. The first can be handled. The second is not recommended. Opiates do not block the activity of LDN (your second question.) Francie, who does not have time to cite scientific articles or sources, but you can look them up if you are so inclined. > > I have read on various sites that LDN should not be taken with opiates (e.g. Morphine), but I have never read a definitive answer as to why this is the case. I have read one doctor saying that LDN will block the action of the opiate and increase pain in the patient. This seems plausible. So, my question is this - What is the reasoning behind not taking LDN with opiates: > > 1. Because it will block the action of the opiate and therefore increase the pain, or > > 2. Because it will interact with the opiate rendering the LDN treatment useless. > > Dr. Ian Zagon has stated that LDN exerts its blockade BETWEEN four and six hours after administering the drug and is then cleared from the system, allowing for the body to be duped into producing more endorphins. > > Please cite scientific articles or sources. Dr. Zagon has also stated that there is a lot of misinformation/heresay on the internet about LDN dosing, etc. > > Thank you for your response. My Mom has NSCLC and takes 30 MG of morphine at night (only) and was wondering if giving her LDN at 11:00 a.m. each morning would be effective. I have also read (and believe) that it does not matter what time of day the LDN is taken. > > Thank you > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 23, 2011 Report Share Posted February 23, 2011 One thing I know of that can happen if you mix LDN with Opiates is sudden withdrawal symptoms which can be very dangerous and life threatening. I say this from experience as I had it happen twice trying to take Tramadol with LDN, which is not considered an opiate but it similar in nature. Do a search on cold turkey withdrawal symptoms if you are not familiar with them. It is a very painful, physical and psychologiocal experience and can kill one. Not to scare anyone but to warn. We all act differently to drugs so we will have varied experiences. I get that , but I suspect anyone who has taken opiates habitually could have problems useing LDN. Be careful!! Quote Link to comment Share on other sites More sharing options...
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