Guest guest Posted June 5, 2006 Report Share Posted June 5, 2006 I remember reading this in earlier posts a couple of years ago. Thanks, , for reminding us of this factor. Has there been any more said about the possibility that there is an increased incidence people of Native American and Asian origins lacking these P450 enzymes, as I seem to remember reading? Terry " ...There are certain things in our nation and in the world about which I am proud to be maladjusted and about which I hope all men of good-will will be maladjusted...Through such maladjustment, I believe that we will be able to emerge from the bleak and desolate midnight of man's inhumanity to man into the bright and glittering daybreak of freedom and justice. " - Dr. Luther King, Jr. - December 18, 1963 __________________________________________________ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 1, 2008 Report Share Posted January 1, 2008 Roni, You wrote: > > ... Anybody see a problem with this?... My only concern would be with the relatively large increment of 1/2 grain, although you can " adjust " that by using food to interfere with absorption. The increments of T4 are about 1/3 of that. Chuck Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 1, 2008 Report Share Posted January 1, 2008 I wouldn't normally see a problem with that, but since you think that taking too much is what caused the AF then why don't you try upping your dose at I/4 grain a week. Also, I know we have discussed this before, but have you treated adrenals? cw -- Dosing I think you probably all remember that I have been dealing with Atrial Fibrillation, apparently coming from too much thyroid. It took me a while, but I finally came to the conclusion that it was too much thyroid (T3)in the Thyrolar all at once. So, I split the dose taking one before breakfast and eating after an hour and one before dinner eating after an hour. That seemed better, but not completely. Then, I split 1 and 1 with food, and my heart seems to feel better. What I want to try now is to add 1/2 grain at lunchtime. Anybody see a problem with this? By the way, I am aware of the lowered absorption which is why I am taking, far a total of 2 grains instead of the 1-1/2 he wanted me to take. I am still feeling very cold hands and feet, and cold (on the insides) hair still falling out too, though not as much, very tired, just don't feel good, lots of pains in back and legs. Roni --------------------------------- Looking for last minute shopping deals? Find them fast with Search. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 1, 2008 Report Share Posted January 1, 2008 I'm using Thyrolar, so the increment of 1/2 grain would be less, wouldn't it? Also, I would take it with food too. Roni Chuck B <gumboyaya@...> wrote: Roni, You wrote: > > ... Anybody see a problem with this?... My only concern would be with the relatively large increment of 1/2 grain, although you can " adjust " that by using food to interfere with absorption. The increments of T4 are about 1/3 of that. Chuck --------------------------------- Be a better friend, newshound, and know-it-all with Mobile. Try it now. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 1, 2008 Report Share Posted January 1, 2008 No Crystal, I haven't been to the doc yet, and I do want to check with him, because I have to have blood work done anyway. Roni Crystal <sweetnwright@...> wrote: I wouldn't normally see a problem with that, but since you think that taking too much is what caused the AF then why don't you try upping your dose at I/4 grain a week. Also, I know we have discussed this before, but have you treated adrenals? cw -- Dosing I think you probably all remember that I have been dealing with Atrial Fibrillation, apparently coming from too much thyroid. It took me a while, but I finally came to the conclusion that it was too much thyroid (T3)in the Thyrolar all at once. So, I split the dose taking one before breakfast and eating after an hour and one before dinner eating after an hour. That seemed better, but not completely. Then, I split 1 and 1 with food, and my heart seems to feel better. What I want to try now is to add 1/2 grain at lunchtime. Anybody see a problem with this? By the way, I am aware of the lowered absorption which is why I am taking, far a total of 2 grains instead of the 1-1/2 he wanted me to take. I am still feeling very cold hands and feet, and cold (on the insides) hair still falling out too, though not as much, very tired, just don't feel good, lots of pains in back and legs. Roni --------------------------------- Looking for last minute shopping deals? Find them fast with Search. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 1, 2008 Report Share Posted January 1, 2008 Roni, How long have you been taking the 1 and 1? If you are going to add the 1/2 too soon, you will probably run into the same problem. When I have changed my dose, I do that dose for at least 2 weeks. You say you are taking that with food now. You are not getting the full benefits doing that. If you are feeling better though, that's important. Venizia -- In hypothyroidism , Roni Molin <matchermaam@...> wrote: > > > I think you probably all remember that I have been dealing with Atrial Fibrillation, apparently > coming from too much thyroid. It took me a while, but I finally came to the conclusion that > it was too much thyroid (T3)in the Thyrolar all at once. > > So, I split the dose taking one before breakfast and eating after an hour and one before > dinner eating after an hour. That seemed better, but not completely. > > Then, I split 1 and 1 with food, and my heart seems to feel better. What I want to try > now is to add 1/2 grain at lunchtime. > > Anybody see a problem with this? By the way, I am aware of the lowered absorption > which is why I am taking, far a total of 2 grains instead of the 1-1/2 he wanted me to > take. I am still feeling very cold hands and feet, and cold (on the insides), hair still > falling out too, though not as much, very tired, just don't feel good, lots of pains in > back and legs. > > Roni > > > --------------------------------- > Looking for last minute shopping deals? Find them fast with Search. > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 1, 2008 Report Share Posted January 1, 2008 Roni Molin wrote: > > > I'm using Thyrolar, so the increment of 1/2 grain would be less, > wouldn't it?... That is supposed to be equivalent to 30 mcg of T4, which comes in 12.5 mcg increments. Chuck Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 2, 2008 Report Share Posted January 2, 2008 Roni, I had to start my thyroid all over again. My hair was falling out too, heartbeat skipping (which I can still feel at night sometimes). I was on 3 1/2 grains. I pretty much cut back to 2 grains, and guess what, my hair falling out has pretty much subsided. But, I am still gaining weight, cold, etc. Now, I am back to square one. I am taking 1 grain of armour, and building back up. Adding 1/4 grain each week. I feel better. Have you looked into your adrenals? I went the HFS and got some raw adrenal, but am looking to get Cortef, and adressing my adrenals. It may be in my head, but I kind of think the adrenal from the HFS is helping a little bit. I am also doing a cleanse, www.ariseandshine.com and this seems to be helping too. What you describe sounds like adrenal to me. Blessings, Roni Molin <matchermaam@...> wrote: I think you probably all remember that I have been dealing with Atrial Fibrillation, apparently coming from too much thyroid. It took me a while, but I finally came to the conclusion that it was too much thyroid (T3)in the Thyrolar all at once. So, I split the dose taking one before breakfast and eating after an hour and one before dinner eating after an hour. That seemed better, but not completely. Then, I split 1 and 1 with food, and my heart seems to feel better. What I want to try now is to add 1/2 grain at lunchtime. Anybody see a problem with this? By the way, I am aware of the lowered absorption which is why I am taking, far a total of 2 grains instead of the 1-1/2 he wanted me to take. I am still feeling very cold hands and feet, and cold (on the insides), hair still falling out too, though not as much, very tired, just don't feel good, lots of pains in back and legs. Roni --------------------------------- Looking for last minute shopping deals? Find them fast with Search. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 3, 2008 Report Share Posted January 3, 2008 No, I haven't had the testing yet, but I will get it. I am currently taking two grains, but with food and divided breakfast and dinner. I want to take more, because I know that the food restricts the absorption, but I am going to take it really slow because I don't want the skipping again, especially since the cardio and the internist both said that could cause stroke and/or heart attack. My hair fallins out has subsided but not stopped and I'm still cold. I'm going to ask the internist about a pituitary test too. I actually feel much better as far as my heart is concerned, but of course it could start up at any time. I have cut back on salt, but not out, added magnesium and hawthorn and potassium on the cardio's suggestion. I take a diuretic when needed, and lots more supplements. So at least I am not on coumadin, or statins, or digoxin or cardizem or any other toxic medications, includintg pain pills and anti-depressants. The only thing I'm on (for the FMS) is ambien, and I seem to be fine with that. If I don't sleep right the pain is terrible. Good luck with your regimen. Roni and Irwin <familyirwin@...> wrote: Roni, I had to start my thyroid all over again. My hair was falling out too, heartbeat skipping (which I can still feel at night sometimes). I was on 3 1/2 grains. I pretty much cut back to 2 grains, and guess what, my hair falling out has pretty much subsided. But, I am still gaining weight, cold, etc. Now, I am back to square one. I am taking 1 grain of armour, and building back up. Adding 1/4 grain each week. I feel better. Have you looked into your adrenals? I went the HFS and got some raw adrenal, but am looking to get Cortef, and adressing my adrenals. It may be in my head, but I kind of think the adrenal from the HFS is helping a little bit. I am also doing a cleanse, www.ariseandshine.com and this seems to be helping too. What you describe sounds like adrenal to me. Blessings, Roni Molin <matchermaam@...> wrote: I think you probably all remember that I have been dealing with Atrial Fibrillation, apparently coming from too much thyroid. It took me a while, but I finally came to the conclusion that it was too much thyroid (T3)in the Thyrolar all at once. So, I split the dose taking one before breakfast and eating after an hour and one before dinner eating after an hour. That seemed better, but not completely. Then, I split 1 and 1 with food, and my heart seems to feel better. What I want to try now is to add 1/2 grain at lunchtime. Anybody see a problem with this? By the way, I am aware of the lowered absorption which is why I am taking, far a total of 2 grains instead of the 1-1/2 he wanted me to take. I am still feeling very cold hands and feet, and cold (on the insides), hair still falling out too, though not as much, very tired, just don't feel good, lots of pains in back and legs. Roni --------------------------------- Looking for last minute shopping deals? Find them fast with Search. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 4, 2008 Report Share Posted January 4, 2008 Roni, The big disadvantage of just taking a larger dose so you can take it with food is that the interference with absorption is highly variable depending on what food is involved. You could be absorbing as much as 80% of the medication one time and less than 20% the next. That makes it harder to understand what is going on and to adjust. I will typically drink a cup of coffee 30-60 minutes after taking the pill. Since it is the same size cup every time, that made the absorption issue at least reproducible. Chuck Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 4, 2008 Report Share Posted January 4, 2008 The reason I am taking it with food is that I don't want the atrial fibrillation to start. I think your point is valid, so I will have to think of a way to do this so that the food or drink is consistent and repeatable. Thanks, that's a good idea. Roni Chuck B <gumboyaya@...> wrote: Roni, The big disadvantage of just taking a larger dose so you can take it with food is that the interference with absorption is highly variable depending on what food is involved. You could be absorbing as much as 80% of the medication one time and less than 20% the next. That makes it harder to understand what is going on and to adjust. I will typically drink a cup of coffee 30-60 minutes after taking the pill. Since it is the same size cup every time, that made the absorption issue at least reproducible. Chuck --------------------------------- Looking for last minute shopping deals? Find them fast with Search. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 1, 2008 Report Share Posted May 1, 2008 , I take mine in the morning all at once. Some folks divide theirs between morning and afternoon. ----- Original Message ----- > Hello, > > It is probably in the files somewhere but I have looked around and > can't find it so I am coming to you all. > > I am wondering if I should take my Iodoral all at once, and if so what > time of day is best, or divide the dose up throughout the day? > > Thanks for the input! > > > > > ------------------------------------ > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 1, 2008 Report Share Posted May 1, 2008 Some split breakfast and lunch and others take all at once (like me). Just take it before 2 pm or you will probably be kept awake. Steph Dosing > Hello, > > It is probably in the files somewhere but I have looked around and > can't find it so I am coming to you all. > > I am wondering if I should take my Iodoral all at once, and if so what > time of day is best, or divide the dose up throughout the day? > > Thanks for the input! > > > > > ------------------------------------ > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 2, 2008 Report Share Posted May 2, 2008 Thank you for the reply. I have been taking it in divided doses without much success so I think I will try it all at once and see if I notice any difference. > > , > > I take mine in the morning all at once. Some folks divide theirs between > morning and afternoon. > > > ----- Original Message ----- > > > > > Hello, > > > > It is probably in the files somewhere but I have looked around and > > can't find it so I am coming to you all. > > > > I am wondering if I should take my Iodoral all at once, and if so what > > time of day is best, or divide the dose up throughout the day? > > > > Thanks for the input! > > > > > > > > > > ------------------------------------ > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 14, 2011 Report Share Posted February 14, 2011 One has to look at the diurnal nature of endorphin secretion to understand HOW they are both right. You get your zenith peak during your normal sleep cycle. You get your penultimate peak during your wake cycle. Taking LDN prior to your zenith peak will give you more bang for your buck than prior to your wake cycle peak. Therefore you will get some increase taking LDN at times other than prior to bedtime but they will not be the most you can get. Hello... what, theoretically, is the correct time for daytime dosing.... Regards Ingrid Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 3, 2011 Report Share Posted November 3, 2011 It is often better that when folk take any form of the active thyroid hormone triiodothyronine (T3) whether synthetic or natural thyroid extract, they take it in split doses, usually twice a day, but also some take it three or more times a day, depending on how high a dose they taking. Usually, the higher the dose, the better it is to take it in 3 or more doses. This is because T3 is the ACTIVE thyroid hormone and works pretty quickly in the body, because it has a very short half life. T3 peaks in the blood a couple or so hours after taking it and the effect starts to diminish after about 6 to 8 hours, so taking a split dose keeps the engine 'topped up'. For some of us, if we take the dose all in one go, say first thing in the morning, by the middle of the afternoon, we experience a slump often wanting a nap and start to lose energy. Levothyroxine (T4) on the other hand is a storage hormone, and has a very long half life of about 7 days. It can take up to 6 weeks for T4 to be used by the body and the same time for it to leave the body, so you only need to take your dose once a day. Some people take all their levothyroxine in one go once a week - and it is quite safe to do so. Hope that helps Luv - Sheila Am I right in thinking that when you take erfa you multiple dose?how many times is it recommended ? What is the thinking behind this? Quote Link to comment Share on other sites More sharing options...
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