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Rational Polypharmacy Naltrexone is a remarkable drug for intractable pain

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http://painsandiego.com/2010/03/03/rsd-complex-regional-pain-syndrome-a-case-report/ The above is a fascinating article – check out the doses these people are taking for pain relief (comments section). Here’s an extract from the article itself In October 2008, adding naltrexone 1 mg by mouth, she became pain free. Since then she has not needed anything for breakthrough pain and on 3/5/09, she reported that her last use of ketamine and oxycodone occurred with the addition of low dose naltrexone.~In 2009, she hiked 30 miles down the Grand Canyon and back up in 3 days.~Naltrexone was later increased to 4.5 mg as she completely tapered off lamotrigine.~By December 2009, the RSD was 98% better and she reported that it was not pain anymore. Medications then were naltrexone 12.5 mg at bedtime and Namenda 55 mg daily in divided doses. She had just a “remnant” of a little buzz, but no crushing except when active, late in the day.~A few months later she slowly tapered off Namenda with no increase in pain; and in October 2010, on my advice she tapered naltrexone 12.5 mg from daily to every third day. There has been no increase in pain but she is reluctant to discontinue naltrexone for fear that RSD may recur.She hikes 2 miles 3 to 4 times a week, does Iron Mountain once a week, does “Silver Sneekers” exercise 1 hour 3 times a week and sleeps well 8 to 10 hours a night without a sleeping pill.~~She remains on low dose naltrexone as her sole medication for this previously disabling neuropathic pain syndrome~~She has returned to part time work and spends a few weeks a month traveling the world, hiking, volunteering, sightseeing. Jayne Crocker www.LDNNow.comImportant! Please sign our LDN petition to the European Parliament by clicking heretel: +44 (0) 7877 492 669Dr Steele MBE, talking about LDNLDNNow are a political/pressure group of individuals dedicated to getting Low Dose Naltrexone (LDN) accepted into modern medicine and trialled for the myriad of uses it shows benefit for. .
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