RE: stress-gut bacteria -disease

[Guest guest]

Whoa, Mark Lyte is a member of my golf club, what a quandry? david lubbock tx.

[low dose naltrexone] stress-gut bacteria -disease

Gut reactionSpencer Hunt The Columbus Dispatch, Ohio 04-11-11 April 10--Doctors and scientists know that stress can lead to illness. They just don't know why. But they are starting to understand where it all might begin. Ohio State University researchers say they have found that stress-related illnesses likely start in an unlikely place -- among the hordes of good and bad bacteria that live in our guts. There are as many as 500 species of bacteria living inside our large intestines. With a combined population that approaches 100 trillion, these microbes help transfer nutrients and vitamins to the body while others help break down wastes and kill harmful food-borne bacteria. , an OSU immunologist and animal physiologist, found that stress in mice activates the immune system to fight off illness, even when there is no threat. Other researchers say 's work might be the first to demonstrate a link between gut bacteria and the immune system. And they say it could help lead the way to new treatments for stress-related diseases in people, including heart disease, inflammatory bowel disease and diarrhea. "It identifies a potential signal, or source of a signal, that's responsible for the inflammatory stress response," said Monika Fleshner, an integrative physiologist at the University of Colorado and president-elect of the Psychoneuroimmunology Research Society. Fleshner said stress causes the human immune system to overproduce a class of proteins called cytokines, which are linked to inflammation or swelling in body tissues. These proteins typically emerge when the body is fighting off a disease. "A lot of symptoms of diseases are caused by the inflammatory response," said. "When we feel sick, those are cytokines signaling to the brain that you should feel sick." It's unclear what health risks high concentrations of cytokines pose to people who aren't sick but are stressed out. said some research suggests that cytokines are a factor in heart disease and chronic inflammatory bowel disease. 's research found that stressed-out mice (aggressive mice are placed in their cages) had high concentrations of inflammatory cytokine in their blood. In some cases, levels of this type of cytokine were 100 times more concentrated in stressed mice than in non-stressed mice. Stress also altered the normal balance of gut bacteria. Colonies of clostridium, a class of 100 species of bacteria, grew 28 percent in mice while another class, bacteroides, shrank nearly in half. established the link between the bacteria and the inflammatory cytokine when he treated the mice with antibiotics. The stressed-out mice treated with antibiotics had low concentrations of bacteria and low levels of the inflammatory cytokine. That meant that the changes in bacteria levels and not some other stress-related factor were influencing cytokine production. The research, published late last year in the journal Brain, Behavior and Immunity, show that what happens in the gut has a direct link to health, said Mark Lyte, a microbial endocrinologist at Texas Tech University's Health Sciences Center. Lyte helped design 's experiment and is a co-author of the study. said more work needs to be done to further define how changes in gut bacteria activate the body's immune response. "Is it a single bacteria or a group that affect this response?" he said. "The other thing is trying to understand which immune cells in the body are producing these cytokines." Fleshner said she also will work to find answers to these questions. "If we could understand a little more about potentially using bacteria to quiet those inflammatory processes, we could have a whole new (treatment) strategy," she said. shunt@...

[Guest guest]

If anyone enjoys reading the science of all this, a book my partner highly recommends and one that is suggested on the LDNScience website is:- Cytokines: Stress and Immunity, Second Editionby P. PlotnikoffCytokine involvement in the immune system's response to stress is now very well documented. Cytokine activity has been implicated in a variety of mental and physical diseases, and has been shown to have a significant role in fueling the vicious circle of depression and illness.The first edition of Cytokines: Stress and Immunity pointed out that the immune system does not stand alone, but is profoundly affected by other organ systems, especially the central nervous and the neuroendocrine systems, with cytokines being the common tool of communication. This edition continues on the trailblazing path of the original to once again present current research that informs our evolving understanding of how cytokines function and the clinical implications of cytokine activity.Completely rewritten by the top authorities in their fields, this volume includes 16 entirely new chapters, which document dramatic new developments. It provides a comprehensive overview of the role of cytokines in the neuroendocrine and immune systems, while also addressing the interactions between these systems. It examines cytokine activity and clinical implications from a number of perspectives, including those of immunology, pharmacology, oncology, endocrinology, and psychiatry. Researchers involved with the most specific aspects of cell signaling as well clinicians dealing with the effects of immunosuppression-related diseases will find a wealth of interesting and instantly applicable information.This new edition begins with an extended dedication and tribute to the late A. Good, the father of modern immunology. It documents the life and groundbreaking achievements of Dr. Good who served as an editor for both the former and current editions of this work. Jayne Crocker www.LDNNow.comImportant! Please sign our LDN petition to the European Parliament by clicking heretel: +44 (0) 7877 492 669Dr Steele MBE, talking about LDNLDNNow are a political/pressure group of individuals dedicated to getting Low Dose Naltrexone (LDN) accepted into modern medicine and trialled for the myriad of uses it shows benefit for. . From: low dose naltrexone [mailto:low dose naltrexone ] On Behalf Of HollySent: 09 January 2004 07:17low dose naltrexone ; z100a2002Subject: Re: [low dose naltrexone] stress-gut bacteria -disease Whoa, Mark Lyte is a member of my golf club, what a quandry? david lubbock tx. [low dose naltrexone] stress-gut bacteria -disease Gut reactionSpencer Hunt The Columbus Dispatch, Ohio 04-11-11 April 10--Doctors and scientists know that stress can lead to illness. They just don't know why. But they are starting to understand where it all might begin. Ohio State University researchers say they have found that stress-related illnesses likely start in an unlikely place -- among the hordes of good and bad bacteria that live in our guts. There are as many as 500 species of bacteria living inside our large intestines. With a combined population that approaches 100 trillion, these microbes help transfer nutrients and vitamins to the body while others help break down wastes and kill harmful food-borne bacteria. , an OSU immunologist and animal physiologist, found that stress in mice activates the immune system to fight off illness, even when there is no threat. Other researchers say 's work might be the first to demonstrate a link between gut bacteria and the immune system. And they say it could help lead the way to new treatments for stress-related diseases in people, including heart disease, inflammatory bowel disease and diarrhea. " It identifies a potential signal, or source of a signal, that's responsible for the inflammatory stress response, " said Monika Fleshner, an integrative physiologist at the University of Colorado and president-elect of the Psychoneuroimmunology Research Society. Fleshner said stress causes the human immune system to overproduce a class of proteins called cytokines, which are linked to inflammation or swelling in body tissues. These proteins typically emerge when the body is fighting off a disease. " A lot of symptoms of diseases are caused by the inflammatory response, " said. " When we feel sick, those are cytokines signaling to the brain that you should feel sick. " It's unclear what health risks high concentrations of cytokines pose to people who aren't sick but are stressed out. said some research suggests that cytokines are a factor in heart disease and chronic inflammatory bowel disease. 's research found that stressed-out mice (aggressive mice are placed in their cages) had high concentrations of inflammatory cytokine in their blood. In some cases, levels of this type of cytokine were 100 times more concentrated in stressed mice than in non-stressed mice. Stress also altered the normal balance of gut bacteria. Colonies of clostridium, a class of 100 species of bacteria, grew 28 percent in mice while another class, bacteroides, shrank nearly in half. established the link between the bacteria and the inflammatory cytokine when he treated the mice with antibiotics. The stressed-out mice treated with antibiotics had low concentrations of bacteria and low levels of the inflammatory cytokine. That meant that the changes in bacteria levels and not some other stress-related factor were influencing cytokine production. The research, published late last year in the journal Brain, Behavior and Immunity, show that what happens in the gut has a direct link to health, said Mark Lyte, a microbial endocrinologist at Texas Tech University's Health Sciences Center. Lyte helped design 's experiment and is a co-author of the study. said more work needs to be done to further define how changes in gut bacteria activate the body's immune response. " Is it a single bacteria or a group that affect this response? " he said. " The other thing is trying to understand which immune cells in the body are producing these cytokines. " Fleshner said she also will work to find answers to these questions. " If we could understand a little more about potentially using bacteria to quiet those inflammatory processes, we could have a whole new (treatment) strategy, " she said. shunt@...

[Guest guest]

Can we have some advantage by practicing Yoga, where the main focus is on to control your stress, and while the exact mechanism to understand that how stress leads to illness takes time we can knowingly or unknowingly get some benefit.RajeevIndiaFrom: z100a2002 <zahavi100@...>low dose naltrexone Sent: Tue, April 12, 2011 1:25:09 AMSubject: [low dose naltrexone] stress-gut bacteria -disease

Gut reaction

Spencer Hunt

The Columbus Dispatch, Ohio

04-11-11

April 10--Doctors and scientists know that stress can lead to illness. They just don't know why.

But they are starting to understand where it all might begin.

Ohio State University researchers say they have found that stress-related illnesses likely start in an unlikely place -- among the hordes of good and bad bacteria that live in our guts.

There are as many as 500 species of bacteria living inside our large intestines. With a combined population that approaches 100 trillion, these microbes help transfer nutrients and vitamins to the body while others help break down wastes and kill harmful food-borne bacteria.

, an OSU immunologist and animal physiologist, found that stress in mice activates the immune system to fight off illness, even when there is no threat.

Other researchers say 's work might be the first to demonstrate a link between gut bacteria and the immune system. And they say it could help lead the way to new treatments for stress-related diseases in people, including heart disease, inflammatory bowel disease and diarrhea.

"It identifies a potential signal, or source of a signal, that's responsible for the inflammatory stress response," said Monika Fleshner, an integrative physiologist at the University of Colorado and president-elect of the Psychoneuroimmunology Research Society.

Fleshner said stress causes the human immune system to overproduce a class of proteins called cytokines, which are linked to inflammation or swelling in body tissues. These proteins typically emerge when the body is fighting off a disease.

"A lot of symptoms of diseases are caused by the inflammatory response," said. "When we feel sick, those are cytokines signaling to the brain that you should feel sick."

It's unclear what health risks high concentrations of cytokines pose to people who aren't sick but are stressed out. said some research suggests that cytokines are a factor in heart disease and chronic inflammatory bowel disease.

's research found that stressed-out mice (aggressive mice are placed in their cages) had high concentrations of inflammatory cytokine in their blood. In some cases, levels of this type of cytokine were 100 times more concentrated in stressed mice than in non-stressed mice.

Stress also altered the normal balance of gut bacteria. Colonies of clostridium, a class of 100 species of bacteria, grew 28 percent in mice while another class, bacteroides, shrank nearly in half.

established the link between the bacteria and the inflammatory cytokine when he treated the mice with antibiotics.

The stressed-out mice treated with antibiotics had low concentrations of bacteria and low levels of the inflammatory cytokine. That meant that the changes in bacteria levels and not some other stress-related factor were influencing cytokine production.

The research, published late last year in the journal Brain, Behavior and Immunity, show that what happens in the gut has a direct link to health, said Mark Lyte, a microbial endocrinologist at Texas Tech University's Health Sciences Center.

Lyte helped design 's experiment and is a co-author of the study.

said more work needs to be done to further define how changes in gut bacteria activate the body's immune response.

"Is it a single bacteria or a group that affect this response?" he said. "The other thing is trying to understand which immune cells in the body are producing these cytokines."

Fleshner said she also will work to find answers to these questions.

"If we could understand a little more about potentially using bacteria to quiet those inflammatory processes, we could have a whole new (treatment) strategy," she said.

shunt@...