Re: Neuro-muscular Spasm in Multiple Sclerosis and LDN

[Guest guest]

, I'm taking LDN for MS also (and ankylosing spondylitis). I've found that

a dose too large causes me a lot of pain. Right now, anything above 3.5 mg

causes me to have the symptoms you describe. But I have good results at 3.5 mg.

It's odd. I take the liquid version, so it's easy for me to adjust the amount.

--Greg

>

> good day

>  

> my ms is all in my legs and i suffer badly with the above, stiffness, neuro

pain, cramps, etc

>  

> ldn seems to exacerbate my symptoms, any suggestions greatly received

>  

> regards/peter/london/ppms

>

[Guest guest]

Hopefully some MS folks will jump in, but as I recall people have mentioned in the early days of LDN use they sometimes see an exacerbation of symptoms before they settle down.  I cannot recall how long you have been taking LDN and at what dose(s).  Hopefully things will settle down for you soon.

 

ALA has been known to help with neuropathic pain - need B vit with it as ALA depletes the Bs

magnesium helps muscle stiffness and cramps for many as well

 

Just two thoughts if you haven't already looked into them.

 

Jaxi

On Wed, Apr 6, 2011 at 11:26 AM, Nicholls <peter.nicholls@...> wrote:

good day

 

my ms is all in my legs and i suffer badly with the above, stiffness, neuro pain, cramps, etc

 

ldn seems to exacerbate my symptoms, any suggestions greatly received

 

regards/peter/london/ppms

[Guest guest]

, As you’ve again increased your dose, I would go back down to 3mg and stay there for a while to see how you get on. Jaxi reminded me about magnesium, absolutely essential and one way of doing this which at the moment is proving very successful for my partner who has terrible spasms and stiffness in his legs is Epsom Bath Salts. At first he wouldn’t try it but after me receiving some benefit/relief for my stiffness etc., he has given it a go. As I can’t get in and out of the bath, I soak my feet in a bowl of water of Epsom salts for about 15 minutes – very relaxing but I imagine if you can have a bath with it, all the better. It’s more cost effective if you buy it online than the chemist as one tub in the chemist is about the right amount for one bath. I’ve just ordered a 5kg bag here http://www.justasoap.co.uk/catalog/epsom-salt-p-207.html Worth a go! Jayne Crocker www.LDNNow.comImportant! Please sign our LDN petition to the European Parliament by clicking heretel: +44 (0) 7877 492 669Dr Steele MBE, talking about LDNLDNNow are a political/pressure group of individuals dedicated to getting Low Dose Naltrexone (LDN) accepted into modern medicine and trialled for the myriad of uses it shows benefit for. . From: low dose naltrexone [mailto:low dose naltrexone ] On Behalf Of jaxiSent: 06 April 2011 17:55 NichollsCc: low dose naltrexone ; mscured Subject: Re: [low dose naltrexone] Neuro-muscular Spasm in Multiple Sclerosis and LDN Hopefully some MS folks will jump in, but as I recall people have mentioned in the early days of LDN use they sometimes see an exacerbation of symptoms before they settle down. I cannot recall how long you have been taking LDN and at what dose(s). Hopefully things will settle down for you soon. ALA has been known to help with neuropathic pain - need B vit with it as ALA depletes the Bsmagnesium helps muscle stiffness and cramps for many as well Just two thoughts if you haven't already looked into them. JaxiOn Wed, Apr 6, 2011 at 11:26 AM, Nicholls <peter.nicholls@...> wrote: good day my ms is all in my legs and i suffer badly with the above, stiffness, neuro pain, cramps, etc ldn seems to exacerbate my symptoms, any suggestions greatly received regards/peter/london/ppms

[Guest guest]

I have MS too. Try the magnesium. I just started magnesium 250 mg and what a

difference. 70% less spasms @ night when it was severe at times.

Very tolerable now. Give it a shot. It may help you.

Sent from my Verizon Wireless BlackBerry

[Guest guest]

hi greg and thanks your reply

do you take any of the neuro-muscular meds such as baclofen ?

regards peter

From: GAsh <gash@...>low dose naltrexone Sent: Wednesday, 6 April 2011, 17:48Subject: [low dose naltrexone] Re: Neuro-muscular Spasm in Multiple Sclerosis and LDN

, I'm taking LDN for MS also (and ankylosing spondylitis). I've found that a dose too large causes me a lot of pain. Right now, anything above 3.5 mg causes me to have the symptoms you describe. But I have good results at 3.5 mg. It's odd. I take the liquid version, so it's easy for me to adjust the amount.--Greg>> good day> > my ms is all in my legs and i suffer badly with the above, stiffness, neuro pain, cramps, etc> > ldn seems to exacerbate my symptoms, any suggestions greatly received> > regards/peter/london/ppms>

[Guest guest]

hi jaxi and appreciate your comments

started ldn december 2010, took 1ml 1st month and now on 4.5mg [capsules] but got scrip from my doc for solution as i consider 4.5 too high, also take calcium and magnesium as receommended by doc bob lawrence

ala don't know that, tell me more

doc offered monthly injection hydroxocobalamin 1ml that is vit b, ever heard ?

regards peter

Hopefully some MS folks will jump in, but as I recall people have mentioned in the early days of LDN use they sometimes see an exacerbation of symptoms before they settle down. I cannot recall how long you have been taking LDN and at what dose(s). Hopefully things will settle down for you soon.

ALA has been known to help with neuropathic pain - need B vit with it as ALA depletes the Bs

magnesium helps muscle stiffness and cramps for many as well

Just two thoughts if you haven't already looked into them.

Jaxi

[Guest guest]

hi jayne and yet again thanks your advice

looking at my scrip from my nhs/doc for ldn solution that i will mail in the morning to dicksons and should receive back early next week

yes solution best choice so i can regulate dose, currently got 4.5mg capsules that from tonight will spilt and mix 50% in juice for 2 days supply, as long as i don't breath the ldn should'nt blow away :-)

epsom salts, would to have a bath but i am a shower-man and poor mobility [en-suite is MY wet room]

brgds peter

,

As you’ve again increased your dose, I would go back down to 3mg and stay there for a while to see how you get on. Jaxi reminded me about magnesium, absolutely essential and one way of doing this which at the moment is proving very successful for my partner who has terrible spasms and stiffness in his legs is Epsom Bath Salts. At first he wouldn’t try it but after me receiving some benefit/relief for my stiffness etc., he has given it a go. As I can’t get in and out of the bath, I soak my feet in a bowl of water of Epsom salts for about 15 minutes – very relaxing but I imagine if you can have a bath with it, all the better. It’s more cost effective if you buy it online than the chemist as one tub in the chemist is about the right amount for one bath.

I’ve just ordered a 5kg bag here http://www.justasoap.co.uk/catalog/epsom-salt-p-207.html

Worth a go!

Jayne Crocker

www.LDNNow.com

Important! Please sign our LDN petition to the European Parliament by clicking here

tel: +44 (0) 7877 492 669

Dr Steele MBE, talking about LDN

LDNNow are a political/pressure group of individuals dedicated to getting Low Dose Naltrexone (LDN) accepted into modern medicine and trialled for the myriad of uses it shows benefit for

[Guest guest]

thanks george, got magnesium and calcium that may help but will also reduce from 4.5 to 2/3 and fingers X

regards peter

I have MS too. Try the magnesium. I just started magnesium 250 mg and what a difference. 70% less spasms @ night when it was severe at times. Very tolerable now. Give it a shot. It may help you.

[Guest guest]

If you are wanting to half the dose I would suggest using say 10 ml of distilled water and disolving the entire pill contents in the water.  Then draw off 5 ml (or half the amount you pick) for your dose of 2.25 mg, storing the other half in the fridge for the next night.  Trying to eyeball half the powder is far too inexact PLUS you do not know for sure how much LDN you are getting that way as there is no guarentee the LDN is evenly mixed with the filler - you could end up with rather lopsided doses.

 

If you find the taste bitter - some do - just chase it with some juice, or put the 5 ml of liquid into the juice and drink that way.  I personally don't mind the taste that much but I know some people do.

 

Jaxi

On Thu, Apr 7, 2011 at 10:41 AM, Nicholls <peter.nicholls@...> wrote:

hi jayne and yet again thanks your advice

 

looking at my scrip from my nhs/doc for ldn solution that i will mail in the morning to dicksons and should receive back early next week

 

yes solution best choice so i can regulate dose, currently got 4.5mg capsules that from tonight will spilt and mix 50% in juice for 2 days supply, as long as i don't breath the ldn should'nt blow away :-)

 

epsom salts, would to have a bath but i am a shower-man and poor mobility [en-suite is MY wet room]

 

brgds peter

 

,

 

As you’ve again increased your dose, I would go back down to 3mg and stay there for a while to see how you get on.  Jaxi reminded me about magnesium, absolutely essential and one way of doing this which at the moment is proving very successful for my partner who has terrible spasms and stiffness in his legs is Epsom Bath Salts.  At first he wouldn’t try it but after me receiving some benefit/relief for my stiffness etc., he has given it a go.  As I can’t get in and out of the bath, I soak my feet in a bowl of water of Epsom salts for about 15 minutes – very relaxing but I imagine if you can have a bath with it, all the better.  It’s more cost effective if you buy it online than the chemist as one tub in the chemist is about the right amount for one bath.

 

I’ve just ordered a 5kg bag here http://www.justasoap.co.uk/catalog/epsom-salt-p-207.html

 

Worth a go!

 

Jayne Crocker

 

www.LDNNow.com

Important!  Please sign our LDN petition to the European Parliament by clicking here

tel: +44 (0) 7877 492 669

Dr Steele MBE, talking about LDN

LDNNow are a political/pressure group of individuals dedicated to getting Low Dose Naltrexone (LDN) accepted into modern medicine and trialled for the myriad of uses it shows benefit for

[Guest guest]

thanks jaxi, well noted

regards peter

If you are wanting to half the dose I would suggest using say 10 ml of distilled water and disolving the entire pill contents in the water. Then draw off 5 ml (or half the amount you pick) for your dose of 2.25 mg, storing the other half in the fridge for the next night. Trying to eyeball half the powder is far too inexact PLUS you do not know for sure how much LDN you are getting that way as there is no guarentee the LDN is evenly mixed with the filler - you could end up with rather lopsided doses.

If you find the taste bitter - some do - just chase it with some juice, or put the 5 ml of liquid into the juice and drink that way. I personally don't mind the taste that much but I know some people do.

Jaxi

[Guest guest]

Hi dividing your capsules is not something recommended. I've been an LDN since 2003, and this is been discussed several times.The actual naltrexone in the capsule is only about the size of a couple grains of sand, so you would most likely not get the amountof naltrexone that you think you're getting and getting mostly filler.Hope this helps.Arlene

Re: [low dose naltrexone] Neuro-muscular Spasm in Multiple Sclerosis and LDN

hi jayne and yet again thanks your advice

looking at my scrip from my nhs/doc for ldn solution that i will mail in the morning to dicksons and should receive back early next week

yes solution best choice so i can regulate dose, currently got 4.5mg capsules that from tonight will spilt and mix 50% in juice for 2 days supply, as long as i don't breath the ldn should'nt blow away :-)

epsom salts, would to have a bath but i am a shower-man and poor mobility [en-suite is MY wet room]

brgds peter

,

As you’ve again increased your dose, I would go back down to 3mg and stay there for a while to see how you get on. Jaxi reminded me about magnesium, absolutely essential and one way of doing this which at the moment is proving very successful for my partner who has terrible spasms and stiffness in his legs is Epsom Bath Salts. At first he wouldn’t try it but after me receiving some benefit/relief for my stiffness etc., he has given it a go. As I can’t get in and out of the bath, I soak my feet in a bowl of water of Epsom salts for about 15 minutes – very relaxing but I imagine if you can have a bath with it, all the better. It’s more cost effective if you buy it online than the chemist as one tub in the chemist is about the right amount for one bath.

I’ve just ordered a 5kg bag here http://www.justasoap.co.uk/catalog/epsom-salt-p-207.html

Worth a go!

Jayne Crocker

www.LDNNow.com

Important! Please sign our LDN petition to the European Parliament by clicking here

tel: +44 (0) 7877 492 669

Dr Steele MBE, talking about LDN

LDNNow are a political/pressure group of individuals dedicated to getting Low Dose Naltrexone (LDN) accepted into modern medicine and trialled for the myriad of uses it shows benefit for

[Guest guest]

, I agree with Arlene for reasons she mentioned.  What might be a solution is to take the 4.5mg pill every other night until the liquid LDN arrives.  This won’t do you any harm at all. Good luck. Jayne Crocker www.LDNNow.comImportant! Please sign our LDN petition to the European Parliament by clicking heretel: +44 (0) 7877 492 669Dr Steele MBE, talking about LDNLDNNow are a political/pressure group of individuals dedicated to getting Low Dose Naltrexone (LDN) accepted into modern medicine and trialled for the myriad of uses it shows benefit for. . From: low dose naltrexone [mailto:low dose naltrexone ] On Behalf Of arlizotte@...Sent: 07 April 2011 17:55 NichollsCc: low dose naltrexone Subject: Re: [low dose naltrexone] Neuro-muscular Spasm in Multiple Sclerosis and LDN Hi dividing your capsules is not something recommended. I've been an LDN since 2003, and this is been discussed several times.The actual naltrexone in the capsule is only about the size of a couple grains of sand, so you would most likely not get the amountof naltrexone that you think you're getting and getting mostly filler.Hope this helps.Arlene Re: [low dose naltrexone] Neuro-muscular Spasm in Multiple Sclerosis and LDN hi jayne and yet again thanks your advice looking at my scrip from my nhs/doc for ldn solution that i will mail in the morning to dicksons and should receive back early next week yes solution best choice so i can regulate dose, currently got 4.5mg capsules that from tonight will spilt and mix 50% in juice for 2 days supply, as long as i don't breath the ldn should'nt blow away :-) epsom salts, would to have a bath but i am a shower-man and poor mobility [en-suite is MY wet room] brgds peter , As you’ve again increased your dose, I would go back down to 3mg and stay there for a while to see how you get on. Jaxi reminded me about magnesium, absolutely essential and one way of doing this which at the moment is proving very successful for my partner who has terrible spasms and stiffness in his legs is Epsom Bath Salts. At first he wouldn’t try it but after me receiving some benefit/relief for my stiffness etc., he has given it a go. As I can’t get in and out of the bath, I soak my feet in a bowl of water of Epsom salts for about 15 minutes – very relaxing but I imagine if you can have a bath with it, all the better. It’s more cost effective if you buy it online than the chemist as one tub in the chemist is about the right amount for one bath. I’ve just ordered a 5kg bag here http://www.justasoap.co.uk/catalog/epsom-salt-p-207.html Worth a go! Jayne CrockerError! Filename not specified. www.LDNNow.comImportant! Please sign our LDN petition to the European Parliament by clicking heretel: +44 (0) 7877 492 669Dr Steele MBE, talking about LDNLDNNow are a political/pressure group of individuals dedicated to getting Low Dose Naltrexone (LDN) accepted into modern medicine and trialled for the myriad of uses it shows benefit for

[Guest guest]

, you might want to consider lowering your dose of calcium for a while. I know the rate has always been 2:1 but I think recent studies are showing different results. Unfortunately I can’t find the studies. Also calcium does build up in your body so you might want to give them a miss for a little while. Just another thought. Jayne Crocker www.LDNNow.comImportant! Please sign our LDN petition to the European Parliament by clicking heretel: +44 (0) 7877 492 669Dr Steele MBE, talking about LDNLDNNow are a political/pressure group of individuals dedicated to getting Low Dose Naltrexone (LDN) accepted into modern medicine and trialled for the myriad of uses it shows benefit for. . From: low dose naltrexone [mailto:low dose naltrexone ] On Behalf Of NichollsSent: 07 April 2011 16:44g21avila@...; low dose naltrexone Subject: Re: [low dose naltrexone] Neuro-muscular Spasm in Multiple Sclerosis and LDN thanks george, got magnesium and calcium that may help but will also reduce from 4.5 to 2/3 and fingers Xregards peter I have MS too. Try the magnesium. I just started magnesium 250 mg and what a difference. 70% less spasms @ night when it was severe at times. Very tolerable now. Give it a shot. It may help you.

[Guest guest]

Noooooo, you can soak your feet in them in a bowl of hot/warm water like I do.  Just as effective – try it, a good way of increasing your magnesium too! Jayne Crocker www.LDNNow.comImportant! Please sign our LDN petition to the European Parliament by clicking heretel: +44 (0) 7877 492 669Dr Steele MBE, talking about LDNLDNNow are a political/pressure group of individuals dedicated to getting Low Dose Naltrexone (LDN) accepted into modern medicine and trialled for the myriad of uses it shows benefit for. . From: Nicholls [mailto:peter.nicholls@...] Sent: 07 April 2011 16:42jaynelcrocker; low dose naltrexone Subject: Re: [low dose naltrexone] Neuro-muscular Spasm in Multiple Sclerosis and LDN hi jayne and yet again thanks your advice looking at my scrip from my nhs/doc for ldn solution that i will mail in the morning to dicksons and should receive back early next week yes solution best choice so i can regulate dose, currently got 4.5mg capsules that from tonight will spilt and mix 50% in juice for 2 days supply, as long as i don't breath the ldn should'nt blow away :-) epsom salts, would to have a bath but i am a shower-man and poor mobility [en-suite is MY wet room] brgds peter , As you’ve again increased your dose, I would go back down to 3mg and stay there for a while to see how you get on. Jaxi reminded me about magnesium, absolutely essential and one way of doing this which at the moment is proving very successful for my partner who has terrible spasms and stiffness in his legs is Epsom Bath Salts. At first he wouldn’t try it but after me receiving some benefit/relief for my stiffness etc., he has given it a go. As I can’t get in and out of the bath, I soak my feet in a bowl of water of Epsom salts for about 15 minutes – very relaxing but I imagine if you can have a bath with it, all the better. It’s more cost effective if you buy it online than the chemist as one tub in the chemist is about the right amount for one bath. I’ve just ordered a 5kg bag here http://www.justasoap.co.uk/catalog/epsom-salt-p-207.html Worth a go! Jayne CrockerError! Filename not specified. www.LDNNow.comImportant! Please sign our LDN petition to the European Parliament by clicking heretel: +44 (0) 7877 492 669Dr Steele MBE, talking about LDNLDNNow are a political/pressure group of individuals dedicated to getting Low Dose Naltrexone (LDN) accepted into modern medicine and trialled for the myriad of uses it shows benefit for

[Guest guest]

I agree Jayne, and have seen it somewhere, that a 1:1 ratio of cal/mag is better

for many.

What's meant by it " building up " in your body, is that certain kinds of calcium

can contribute to stone formation. My Mom says, " Rocks in, rocks out " , meaning

that if you take a calcium that is derived from rocks, like Ca carbonate or

dolomite, it will easily make stones in your body if not kept in solution by

enough magnesium. One answer is to use calcium citrate.

I'm now taking 1200 mg. CA/day and approx. 1800 mg. mag./day. I just about have

no spasms at all now. I think this is why.

K.C.

>

> , you might want to consider lowering your dose of calcium for a while.

> I know the rate has always been 2:1 but I think recent studies are showing

> different results. Unfortunately I can't find the studies. Also calcium

> does build up in your body so you might want to give them a miss for a

> little while. Just another thought.

>

>

>

> Jayne Crocker

>

> [mailto:low dose naltrexone ] On Behalf Of Nicholls

> Subject: Re: [low dose naltrexone] Neuro-muscular Spasm in Multiple Sclerosis

> and LDN

> thanks george, got magnesium and calcium that may help but will also reduce

> from 4.5 to 2/3 and fingers X

>

> regards peter

>

>

> I have MS too. Try the magnesium. I just started magnesium 250 mg and what a

> difference. 70% less spasms @ night when it was severe at times.

> Very tolerable now. Give it a shot. It may help you.

>

>

>