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Hello,I have had an aggressive MS since 1986. Have been on CaEAP for 23 yrs. That held me in good stead for many years. More trouble in the last 10 yrs. Recently, in the last 2 years been on tysabri. Was hospitalized in February for 5 days with a bleeding ulcer. Stopped tysabri, felt my immune system got too compromised that the h-pylori bacteria took hold to create the bleeding ulcer. I wanted to try the low dose naltrexone to see if that would help me. I started on 4.5 mg and had a bad reaction, dose too high. Then started on 3 mg ldn I took it for a week and have had such serious spasms and was in such terriblepain, felt that dose was too high and will start on 1mg ldn on Monday. I have continued to get much worse. I am at a point now that I am having a hard time getting up and transferring. Question? Does anyone have experience with the severe spasms and ldn and it getting better and having recovering of symptoms and regaining of strength and functioning? Does anyone have experience of taking tysabri and ldn? I am feeling at a crossroads and wondering what I should do next so I don’t become a complete invalid. Thank You so very much for any encouragement and assistance you can offer me,Johanna

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